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Search results 1 to 100 out of 551 for Trim5

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
85363 | TRIM5
Type: gene
Organism: human
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Gene
308906 | Trim5
Type: gene
Organism: rat
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Gene
503563 | TRIM5
Type: gene
Organism: chimpanzee
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Gene
505265 | TRIM5
Type: gene
Organism: cattle
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Gene
574288 | TRIM5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3646853 | Trim5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032917 | TRIM5
Type: Family
Description: Tripartite motif-containing protein 5 (TRIM5) is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus invasion of the target cell cytoplasm []. It is a regulator of autophagy [].Interestingly, while each primate species has a single TRIM5 gene, mice have at least seven TRIM5 homologues that cluster into two groups, Trim12a, -b, and -c and Trim30a, -b, -c, and -d. The three Trim12 proteins activated innate immune signaling, while the Trim30 proteins did not [].
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Publication
19147168 | J:162981
First Author: Tareen SU
Year: 2009
Journal: Virology
Title: An expanded clade of rodent Trim5 genes.
Volume: 385
Issue: 2
Pages: 473-83
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Publication
19238338 | J:146217
First Author: Johnson WE
Year: 2009
Journal: Immunogenetics
Title: Molecular evolution of the antiretroviral TRIM5 gene.
Volume: 61
Issue: 3
Pages: 163-76
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Publication
21512573 | -
First Author: Pertel T
Year: 2011
Journal: Nature
Title: TRIM5 is an innate immune sensor for the retrovirus capsid lattice.
Volume: 472
Issue: 7343
Pages: 361-5
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Publication
26468522 | -
First Author: Lascano J
Year: 2015
Journal: J Virol
Title: TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.
Volume: 90
Issue: 1
Pages: 308-16
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Publication
25127057 | -
First Author: Mandell MA
Year: 2014
Journal: Dev Cell
Title: TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
Volume: 30
Issue: 4
Pages: 394-409
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Protein
Q3UUU9
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: true
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Protein
Q99PQ1
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
D3YVI1
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
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Protein
Q6P6F6
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
A0A0R4J1B5
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Protein
Q504P5
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
D3YYU4
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
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Protein
Q8CC73
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Publication
38652660 | J:349812
First Author: Schäfer A
Year: 2024
Journal: Cell Rep
Title: Mapping of susceptibility loci for Ebola virus pathogenesis in mice.
Volume: 43
Issue: 5
Pages: 114127
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Protein Coding Gene
MGP_CAROLIEiJ_G0030188 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3646853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032516 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033221 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013404 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031296 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6507606
Assay Type: RT-PCR
Annotation Date: 2021-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6507621
Age: postnatal
Image: 13
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6507606
Assay Type: RT-PCR
Annotation Date: 2021-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6507621
Age: postnatal
Image: 13
Specimen Label: gHO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4945113
Age: embryonic day 11.5
Image: g00568 E11.5
Specimen Label: g00568 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945113
Age: embryonic day 15.5
Image: g00568 E15.5
Specimen Label: g00568 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885293
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945113
Age: postnatal day 7
Image: g00568 P7
Specimen Label: g00568 P7
Detected: true
Specimen Num: 3
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Publication
19706712 | J:248997
First Author: Boon AC
Year: 2009
Journal: J Virol
Title: Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.
Volume: 83
Issue: 20
Pages: 10417-26
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Publication
32099945 | J:282838
First Author: Fan J
Year: 2020
Journal: J Endocr Soc
Title: Amhr2-Cre-Mediated Global Tspo Knockout.
Volume: 4
Issue: 2
Pages: bvaa001
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
26503954 | J:287707
First Author: Chang TH
Year: 2015
Journal: J Immunol
Title: Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6.
Volume: 195
Issue: 11
Pages: 5367-79
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Publication
16445939 | -
First Author: Mateja A
Year: 2006
Journal: J Mol Biol
Title: The dimerization mechanism of LIS1 and its implication for proteins containing the LisH motif.
Volume: 357
Issue: 2
Pages: 621-31
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Protein Domain
IPR027370 | Znf-RING_euk
Type: Domain
Description: This zinc-finger is typical of ubiquitin ligases from eukaryotes [, ]. This domain can also be found in Tripartite motif-containing proteins (TRIM), including TRIM5 from humans, a capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses [, ].
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Publication
22078707 | J:196249
 
First Author: Lukic Z
Year: 2011
Journal: Retrovirology
Title: TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions.
Volume: 8
Pages: 93
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Protein Coding Gene
MGI:4821183 | Trim12c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0030187 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:4821257 | Trim30c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0030190 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:1923931 | Trim12a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0032709 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0032712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0032715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3035181 | Trim30d
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0032717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032690 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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