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Search results 1 to 100 out of 117 for Uba2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
10054 | UBA2
Type: gene
Organism: human
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Gene
549845 | uba2
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR030661 | Uba2
Type: Family
Description: The SUMO activating enzyme E1 enzyme facilitates conjugation of ubiquitin and ubiquitin-like proteins through adenylation, thioester transfer within E1, and thioester transfer from E1 to E2 conjugating proteins []. This entry represents a subunit of the E1 enzyme, including Uba2 from yeasts []and its homologue, SAE2 from animals []. E1 enzymes mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 [, ].
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Gene
308508 | Uba2
Type: gene
Organism: rat
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Gene
476490 | UBA2
Type: gene
Organism: dog, domestic
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Gene
468823 | UBA2
Type: gene
Organism: chimpanzee
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Gene
507005 | UBA2
Type: gene
Organism: cattle
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Gene
415784 | UBA2
Type: gene
Organism: chicken
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Gene
406672 | uba2
Type: gene
Organism: zebrafish
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Gene
705808 | UBA2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1858313 | Uba2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
11481243 | -
First Author: Azuma Y
Year: 2001
Journal: FASEB J
Title: Expression and regulation of the mammalian SUMO-1 E1 enzyme.
Volume: 15
Issue: 10
Pages: 1825-7
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Publication
17643372 | -
First Author: Wang J
Year: 2007
Journal: Mol Cell
Title: The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.
Volume: 27
Issue: 2
Pages: 228-37
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Publication
20164921 | -
First Author: Olsen SK
Year: 2010
Journal: Nature
Title: Active site remodelling accompanies thioester bond formation in the SUMO E1.
Volume: 463
Issue: 7283
Pages: 906-12
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Protein
A2BH29
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Publication
7629121 | J:27427
First Author: Dohmen RJ
Year: 1995
Journal: J Biol Chem
Title: An essential yeast gene encoding a homolog of ubiquitin-activating enzyme.
Volume: 270
Issue: 30
Pages: 18099-109
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Protein
H3BLM2
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: true
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Protein
H3BLR3
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Publication
15660128 | -
First Author: Lois LM
Year: 2005
Journal: EMBO J
Title: Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1.
Volume: 24
Issue: 3
Pages: 439-51
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Protein
Q9Z1F9
Organism: Mus musculus/domesticus
Length: 638  
Fragment?: false
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Publication
10905345 | J:63475
First Author: Schwienhorst I
Year: 2000
Journal: Mol Gen Genet
Title: SUMO conjugation and deconjugation.
Volume: 263
Issue: 5
Pages: 771-86
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Protein Coding Gene
MGP_CAROLIEiJ_G0029569 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032072 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031985 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1858313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031973 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031221 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012804 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030668 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287122
Stage: TS22
Assay Id: MGI:7778438
Age: embryonic day 14.5
Specimen Label: E14.5 Epi
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287124
Stage: TS24
Assay Id: MGI:7778438
Age: embryonic day 16.5
Specimen Label: E16.5 Epi
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287126
Stage: TS26
Assay Id: MGI:7778438
Age: embryonic day 18.5
Specimen Label: E18.5 Epi
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287127
Stage: TS27
Assay Id: MGI:7778438
Age: postnatal day 0.5
Specimen Label: P0.5 Epi
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784122
Stage: TS22
Assay Id: MGI:7778438
Age: embryonic day 14.5
Specimen Label: E14.5 Fiber
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784124
Stage: TS24
Assay Id: MGI:7778438
Age: embryonic day 16.5
Specimen Label: E16.5 Fiber
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784126
Stage: TS26
Assay Id: MGI:7778438
Age: embryonic day 18.5
Specimen Label: E18.5 Fiber
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7778425
Assay Type: RT-PCR
Annotation Date: 2024-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784127
Stage: TS27
Assay Id: MGI:7778438
Age: postnatal day 0.5
Specimen Label: P0.5 Fiber
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5763285
Age: embryonic day 9.5
Image: 1A 9.5dpc
Specimen Label: 1A 9.5dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5763285
Age: embryonic day 10.5
Image: 1A 10.5dpc
Specimen Label: 1A 10.5dpc
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5763285
Age: embryonic day 11.5
Image: 1A 11.5dpc
Specimen Label: 1A 11.5dpc
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Pattern: Widespread
Stage: TS12
Assay Id: MGI:5763285
Age: embryonic day 8.0
Image: 1A 8.0dpc
Specimen Label: 1A 8.0dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Widespread
Stage: TS15
Assay Id: MGI:5763285
Age: embryonic day 9.5
Image: 1A 9.5dpc
Specimen Label: 1A 9.5dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Widespread
Stage: TS17
Assay Id: MGI:5763285
Age: embryonic day 10.5
Image: 1A 10.5dpc
Specimen Label: 1A 10.5dpc
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Widespread
Stage: TS19
Assay Id: MGI:5763285
Age: embryonic day 11.5
Image: 1A 11.5dpc
Specimen Label: 1A 11.5dpc
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Widespread
Stage: TS19
Assay Id: MGI:5763285
Age: embryonic day 11.5
Image: S1 left
Specimen Label: S1 left
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3273212
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:5763285
Age: embryonic day 8.0
Image: 1A 8.0dpc
Specimen Label: 1A 8.0dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5763285
Age: embryonic day 9.5
Image: 1A 9.5dpc
Specimen Label: 1A 9.5dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5763285
Age: embryonic day 10.5
Image: 1A 10.5dpc
Specimen Label: 1A 10.5dpc
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5763271
Assay Type: RNA in situ
Annotation Date: 2016-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611719
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5763285
Age: embryonic day 11.5
Image: 1A 11.5dpc
Specimen Label: 1A 11.5dpc
Detected: true
Specimen Num: 4
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Publication
- | J:62032
   
First Author: Mizunuma N
Year: 1999
Journal: GenBank Submission
Title: Mus musculus anthracycline-associated resistance (Arx) mRNA, complete cds
Pages: U35833
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Publication
23832333 | J:355660
First Author: Kanemaru A
Year: 2013
Journal: Biosci Biotechnol Biochem
Title: High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system.
Volume: 77
Issue: 7
Pages: 1575-8
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Publication
21554500 | J:186944
First Author: Ban R
Year: 2011
Journal: Genes Cells
Title: Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis.
Volume: 16
Issue: 6
Pages: 652-69
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Publication
15094046 | J:359368
First Author: Uchimura Y
Year: 2004
Journal: FEBS Lett
Title: Generation of SUMO-1 modified proteins in E. coli: towards understanding the biochemistry/structural biology of the SUMO-1 pathway.
Volume: 564
Issue: 1-2
Pages: 85-90
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Publication
15569683 | J:96947
First Author: Takahashi H
Year: 2005
Journal: J Biol Chem
Title: Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein.
Volume: 280
Issue: 7
Pages: 5611-21
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Publication
21931855 | J:177922
First Author: Costa MW
Year: 2011
Journal: PLoS One
Title: Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.
Volume: 6
Issue: 9
Pages: e24812
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Publication
29883638 | J:356303
 
First Author: Zhao Y
Year: 2018
Journal: Exp Eye Res
Title: A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells.
Volume: 175
Pages: 56-72
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Publication
15767674 | J:97581
First Author: Gómez-del Arco P
Year: 2005
Journal: Mol Cell Biol
Title: Ikaros SUMOylation: switching out of repression.
Volume: 25
Issue: 7
Pages: 2688-97
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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