| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Vps36 is a subunit of ESCRT-II, a protein complex involved in driving protein sorting from endosomes to lysosomes. The GLUE domain of Vps36 allows for a tight interaction to occur between the protein and Vps28, a subunit of ESCRT-I. This interaction is critical for ubiquitinated cargo progression from early to late endosomes []. The multivesicular body (MVB) protein-sorting pathway targets transmembraneproteins either for degradation or for function in the vacuole/lysosomes. Thesignal for entry into this pathway is monoubiquitination of protein cargo,which results in incorporation of cargo into luminal vesicles at lateendosomes. Another crucial player is phosphatidylinositol 3-phosphate(PtdINS(3)P), which is enriched on early endosomes and on the luminal vesiclesof MVBs. ESCRT (endosomal sorting complex required for transport)-I, -II and -III complexes are critical for MVB budding and sorting ofmonoubiquitinated cargo into the luminal vesicles []. Various Ub-binding domains(UBDs), such as UIM, UEV and NZF are found in suchmachineries [, ].The Vps 36 subunit of the ESCRT-II trafficking complex binds bothphosphoinositides and ubiquitin. All members of the Vps36 family contain adivergent GRAM/PH-like domain; yeast and some other fungi have one or twoNZF domains inserted in the GRAM/PH-like domain [, ]. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
386
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
328
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
386
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Williams RL |
| Year: |
2007 |
| Journal: |
Nat Rev Mol Cell Biol |
| Title: |
The emerging shape of the ESCRT machinery. |
| Volume: |
8 |
| Issue: |
5 |
| Pages: |
355-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Teo H |
| Year: |
2006 |
| Journal: |
Cell |
| Title: |
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. |
| Volume: |
125 |
| Issue: |
1 |
| Pages: |
99-111 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gill DJ |
| Year: |
2007 |
| Journal: |
EMBO J |
| Title: |
Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. |
| Volume: |
26 |
| Issue: |
2 |
| Pages: |
600-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Slagsvold T |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain. |
| Volume: |
280 |
| Issue: |
20 |
| Pages: |
19600-6 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611817 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529404 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
BA1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668117 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529404 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
FNP |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529404 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
Heart |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640517 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529404 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
Limbs |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611819 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529432 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
BA1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668119 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529432 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
FNP |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529432 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
Heart |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529002 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529432 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
Limbs |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611817 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
E10.5 BA1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668117 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
E10.5 FNP |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
E10.5 Heart |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640517 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 10.5 |
| Image: |
7 |
|
| Specimen Label: |
E10.5 Limbs |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611819 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
E11.5 BA1 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668119 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
E11.5 FNP |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
E11.5 Heart |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7529445 |
| Age: |
embryonic day 11.5 |
| Image: |
7 |
|
| Specimen Label: |
E11.5 Limbs |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611813 |
| Pattern: |
Regionally restricted |
| Stage: |
TS13 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 8.25-8.75 |
| Image: |
1A |
| Note: |
Expression was enriched at the distal tip. |
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 9.5 |
| Image: |
1B |
| Note: |
Expression remained strongest at the rostral tip with reduced expression extending as far as its caudal boundary. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668115 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 9.5 |
| Image: |
1B |
| Note: |
High enrichment was present at the rostral tip with attenuated signal caudally; signal persisted along the dorsal anterior-posterior axis. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1677817 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2A |
|
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1680817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2B |
| Note: |
Expression was highest at the rim of the nasal pit perimeter. |
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1680819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3B |
| Note: |
Expression was highest in the posterior edge bordering the oral cavity. |
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640615 |
| Pattern: |
Graded |
| Stage: |
TS15 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 9.5 |
| Image: |
1B |
| Note: |
Expression in a gradient with the highest level at the distal tip. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640617 |
| Pattern: |
Graded |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2A |
| Note: |
Expression was highest in the apical ectodermal ridge and reduced towards the center of the bud. |
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3A |
| Note: |
Expression appeared highest distally, with attenuated signal at the core of the limb buds. |
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1735519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3B |
| Note: |
Signal in the mandibular process was highest in the medial anterior tips. |
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3642217 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529371 |
| Age: |
embryonic day 10.5 |
| Image: |
6E |
| Note: |
Expression was enriched in the cranial neural crest cells (CCNC) of the trigeminal stream. Co-localization was observed with the CCNC marker, Sox10. |
| Specimen Label: |
6E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1647017 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529371 |
| Age: |
embryonic day 10.5 |
| Image: |
6E |
| Note: |
Expression was enriched in neuroepithelium. |
| Specimen Label: |
6E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603913 |
| Pattern: |
Ubiquitous |
| Stage: |
TS13 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 8.25-8.75 |
| Image: |
1A |
|
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603915 |
| Pattern: |
Ubiquitous |
| Stage: |
TS15 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 9.5 |
| Image: |
1B |
|
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
| Pattern: |
Ubiquitous |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2A |
|
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
| Pattern: |
Ubiquitous |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2B |
|
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603919 |
| Pattern: |
Ubiquitous |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3A |
|
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603919 |
| Pattern: |
Ubiquitous |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3B |
|
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528964 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3185817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529371 |
| Age: |
embryonic day 10.5 |
| Image: |
6E |
| Note: |
Expression was enriched in surface cephalic epithelium. |
| Specimen Label: |
6E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1638217 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2B |
| Note: |
Expression was highest in the most anterior edge of the mandibular process. |
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273213 |
| Pattern: |
Widespread |
| Stage: |
TS13 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 8.25-8.75 |
| Image: |
1A |
| Note: |
High enriched expression was detected in the neural folds along the entirety of the dorsal anterior-posterior axis. |
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1627215 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 9.5 |
| Image: |
1B |
|
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1627217 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2B |
| Note: |
Expression was highest in the posterior edge with lower uniform expression seen throughout the rest of the arch. |
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1627219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3B |
|
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1677917 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2A |
| Note: |
Expression in the emerging hindlimb is most apparent at the most distal tip with reduced expression proximally. |
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1677919 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3A |
| Note: |
Expression appeared highest distally, with attenuated signal at the core of the limb buds. |
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1680517 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2B |
| Note: |
Expression was highest at the rim of the nasal pit perimeter. |
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1680519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3B |
| Note: |
Expression was highest in the lateral edges. |
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1638817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 10.5 |
| Image: |
2B |
| Note: |
Expression was highest in the most posterior edge of the maxillary process. |
| Specimen Label: |
2B |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7528817 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1638819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7529109 |
| Age: |
embryonic day 11.5 |
| Image: |
3B |
| Note: |
Expression was highest in the lateral edges. |
| Specimen Label: |
3B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Strausberg R |
| Year: |
2001 |
| Journal: |
GenBank Submission |
| Title: |
Mus musculus, clone MGC: 19122 IMAGE: 4210911, mRNA, complete cds |
|
|
| Pages: |
BC010811 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith J |
| Year: |
2015 |
| Journal: |
J Biomol Tech |
| Title: |
Angiogenesis QTL on Mouse Chromosome 8 Colocalizes with Differential β-Defensin Expression. |
| Volume: |
26 |
| Issue: |
2 |
| Pages: |
45-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hermosilla Aguayo V |
| Year: |
2023 |
| Journal: |
Dev Biol |
| Title: |
ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. |
| Volume: |
503 |
|
| Pages: |
25-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2012 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|