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Search results 1 to 100 out of 462 for Xiap

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
331 | XIAP
Type: gene
Organism: human
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Gene
594971 | xiap
Type: gene
Organism: frog, western clawed
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Gene
63879 | Xiap
Type: gene
Organism: rat
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Gene
442989 | XIAP
Type: gene
Organism: dog, domestic
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Gene
473765 | XIAP
Type: gene
Organism: chimpanzee
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Gene
281647 | XIAP
Type: gene
Organism: cattle
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Gene
373108 | xiap
Type: gene
Organism: zebrafish
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Gene
698057 | XIAP
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:107572 | Xiap
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:5881971
Assay Type: Western blot
Annotation Date: 2017-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5881972
Age: embryonic day 15.0
Image: 7
Specimen Label: XIAP
Detected: true
Specimen Num: 2
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Gene
54739 | XAF1
Type: gene
Organism: human
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Gene
106480735 | XIAP-AS1
Type: gene
Organism: human
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Publication
35687753 | J:328235
First Author: Chiang SCC
Year: 2022
Journal: Blood
Title: Quercetin ameliorates XIAP deficiency-associated hyperinflammation.
Volume: 140
Issue: 7
Pages: 706-715
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Publication
23954782 | J:202766
First Author: Unsain N
Year: 2013
Journal: Cell Rep
Title: XIAP regulates caspase activity in degenerating axons.
Volume: 4
Issue: 4
Pages: 751-63
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Publication
18708583 | J:138979
First Author: Schile AJ
Year: 2008
Journal: Genes Dev
Title: Regulation of apoptosis by XIAP ubiquitin-ligase activity.
Volume: 22
Issue: 16
Pages: 2256-66
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Publication
18769721 | J:162718
First Author: Bauler LD
Year: 2008
Journal: PLoS Pathog
Title: XIAP regulates cytosol-specific innate immunity to Listeria infection.
Volume: 4
Issue: 8
Pages: e1000142
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Publication
8643514 | J:33039
First Author: Uren AG
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.
Volume: 93
Issue: 10
Pages: 4974-8
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Publication
18692482 | J:140321
First Author: Resch U
Year: 2008
Journal: Biochem Biophys Res Commun
Title: XIAP regulates intracellular ROS by enhancing antioxidant gene expression.
Volume: 375
Issue: 1
Pages: 156-61
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Publication
35026350 | J:322618
First Author: Li Y
Year: 2022
Journal: Biochim Biophys Acta Mol Cell Res
Title: Overexpression of XIAP inhibits cisplatin-induced hair cell loss.
Volume: 1869
Issue: 4
Pages: 119204
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Publication
24882010 | J:211783
First Author: Yabal M
Year: 2014
Journal: Cell Rep
Title: XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.
Volume: 7
Issue: 6
Pages: 1796-808
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Publication
35437868 | J:326208
First Author: Daoud M
Year: 2022
Journal: EMBO Rep
Title: XIAP promotes melanoma growth by inducing tumour neutrophil infiltration.
Volume: 23
Issue: 6
Pages: e53608
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Publication
17562856 | J:125016
First Author: Ho AT
Year: 2007
Journal: Mol Cell Biol
Title: XIAP activity dictates Apaf-1 dependency for caspase 9 activation.
Volume: 27
Issue: 16
Pages: 5673-85
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Publication
19626005 | J:151786
First Author: Jost PJ
Year: 2009
Journal: Nature
Title: XIAP discriminates between type I and type II FAS-induced apoptosis.
Volume: 460
Issue: 7258
Pages: 1035-9
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Publication
28656888 | J:257146
   
First Author: Hu W
Year: 2017
Journal: Elife
Title: The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms.
Volume: 6
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Publication
33713642 | J:315696
 
First Author: Gao D
Year: 2021
Journal: Biochem Pharmacol
Title: XIAP inhibits gentamicin-induced hair cell damage and ototoxicity through the caspase-3/9 pathway.
Volume: 186
Pages: 114513
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Publication
16154537 | J:100857
First Author: Kim HS
Year: 2005
Journal: Biochem Biophys Res Commun
Title: IFN-gamma sensitizes MIN6N8 insulinoma cells to TNF-alpha-induced apoptosis by inhibiting NF-kappaB-mediated XIAP upregulation.
Volume: 336
Issue: 3
Pages: 847-53
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Publication
12812761 | J:83979
First Author: Trapp T
Year: 2003
Journal: Mol Cell Neurosci
Title: Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia.
Volume: 23
Issue: 2
Pages: 302-13
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Publication
16543147 | J:108000
First Author: Mufti AR
Year: 2006
Journal: Mol Cell
Title: XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders.
Volume: 21
Issue: 6
Pages: 775-85
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Publication
16566922 | J:111367
First Author: Wootz H
Year: 2006
Journal: Exp Cell Res
Title: XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.
Volume: 312
Issue: 10
Pages: 1890-8
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Publication
29250796 | J:261016
First Author: Yu Y
Year: 2018
Journal: Int J Cancer
Title: XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability.
Volume: 142
Issue: 10
Pages: 2040-2055
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Publication
18055022 | J:130391
First Author: Moore CS
Year: 2008
Journal: J Neuroimmunol
Title: Inhibitor of apoptosis protein (IAP) profiling in experimental autoimmune encephalomyelitis (EAE) implicates increased XIAP in T lymphocytes.
Volume: 193
Issue: 1-2
Pages: 94-105
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Publication
22607974 | J:188020
First Author: Damgaard RB
Year: 2012
Journal: Mol Cell
Title: The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
Volume: 46
Issue: 6
Pages: 746-58
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Publication
19595300 | J:151591
First Author: Rumble JM
Year: 2009
Journal: Cell Immunol
Title: Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP).
Volume: 259
Issue: 1
Pages: 82-9
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Publication
20427267 | J:164544
First Author: Prakash H
Year: 2010
Journal: J Biol Chem
Title: Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice.
Volume: 285
Issue: 26
Pages: 20291-302
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Publication
14623868 | J:86711
First Author: Potts PR
Year: 2003
Journal: J Cell Biol
Title: Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.
Volume: 163
Issue: 4
Pages: 789-99
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Publication
28300832 | J:264861
First Author: Liu Y
Year: 2017
Journal: Cell Death Dis
Title: Deletion Of XIAP reduces the severity of acute pancreatitis via regulation of cell death and nuclear factor-κB activity.
Volume: 8
Issue: 3
Pages: e2685
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Publication
32015347 | J:308690
First Author: Coccia E
Year: 2020
Journal: Cell Death Dis
Title: SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L.
Volume: 11
Issue: 2
Pages: 82
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Publication
30585320 | J:273468
First Author: Müller N
Year: 2019
Journal: Eur J Immunol
Title: XIAP deficiency in hematopoietic recipient cells drives donor T-cell activation and GvHD in mice.
Volume: 49
Issue: 3
Pages: 504-507
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Publication
29899110 | J:267102
First Author: Rijal D
Year: 2018
Journal: J Biol Chem
Title: Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.
Volume: 293
Issue: 30
Pages: 11913-11927
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Publication
28723569 | J:254238
First Author: Lawlor KE
Year: 2017
Journal: Cell Rep
Title: XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Volume: 20
Issue: 3
Pages: 668-682
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Publication
11602612 | J:205682
First Author: Martins LM
Year: 2002
Journal: J Biol Chem
Title: The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif.
Volume: 277
Issue: 1
Pages: 439-44
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Publication
34025452 | J:321257
 
First Author: He L
Year: 2021
Journal: Front Physiol
Title: XIAP Knockdown in Alcohol-Associated Liver Disease Models Exhibits Divergent in vitro and in vivo Phenotypes Owing to a Potential Zonal Inhibitory Role of SMAC.
Volume: 12
Pages: 664222
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Publication
30389919 | J:269496
First Author: Koren E
Year: 2018
Journal: Nat Commun
Title: ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.
Volume: 9
Issue: 1
Pages: 4582
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Publication
19473982 | J:153190
First Author: Van Themsche C
Year: 2009
Journal: J Biol Chem
Title: X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization.
Volume: 284
Issue: 31
Pages: 20462-6
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Publication
23788729 | J:199466
First Author: Fuchs Y
Year: 2013
Journal: Science
Title: Sept4/ARTS regulates stem cell apoptosis and skin regeneration.
Volume: 341
Issue: 6143
Pages: 286-9
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Publication
15207275 | J:91241
First Author: Wang X
Year: 2004
Journal: Neurobiol Dis
Title: X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
Volume: 16
Issue: 1
Pages: 179-89
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Protein Coding Gene
MGI:3772572 | Xaf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
679600 | Xaf1
Type: gene
Organism: rat
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Gene
455244 | XAF1
Type: gene
Organism: chimpanzee
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Gene
509740 | XAF1
Type: gene
Organism: cattle
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Gene
417677 | XAF1
Type: gene
Organism: chicken
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Gene
767709 | xaf1
Type: gene
Organism: zebrafish
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Gene
713425 | XAF1
Type: gene
Organism: macaque, rhesus
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Gene
119871834 | XAF1
Type: gene
Organism: dog, domestic
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Publication
12667469 | J:131674
First Author: Crocker SJ
Year: 2003
Journal: Neurobiol Dis
Title: Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice.
Volume: 12
Issue: 2
Pages: 150-61
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Publication
29386580 | J:258478
First Author: Hsieh WC
Year: 2018
Journal: Nat Commun
Title: IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Volume: 9
Issue: 1
Pages: 463
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Publication
20154138 | J:161716
First Author: Brady GF
Year: 2010
Journal: Mol Cell Biol
Title: Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.
Volume: 30
Issue: 8
Pages: 1923-36
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Publication
20584313 | J:163854
 
First Author: Owens TW
Year: 2010
Journal: BMC Dev Biol
Title: Analysis of inhibitor of apoptosis protein family expression during mammary gland development.
Volume: 10
Pages: 71
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Protein
Q60989
Organism: Mus musculus/domesticus
Length: 496  
Fragment?: false
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Publication
18684108 | J:140404
First Author: Rumble JM
Year: 2008
Journal: Biochem J
Title: Apoptotic sensitivity of murine IAP-deficient cells.
Volume: 415
Issue: 1
Pages: 21-5
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Publication
20129247 | J:156930
First Author: Mehrotra S
Year: 2010
Journal: Cancer Cell
Title: IAP regulation of metastasis.
Volume: 17
Issue: 1
Pages: 53-64
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Publication
11313486 | J:74251
First Author: Harlin H
Year: 2001
Journal: Mol Cell Biol
Title: Characterization of XIAP-deficient mice.
Volume: 21
Issue: 10
Pages: 3604-8
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Publication
18259199 | J:150992
First Author: Hwang C
Year: 2008
Journal: Cell Death Differ
Title: X-linked inhibitor of apoptosis deficiency in the TRAMP mouse prostate cancer model.
Volume: 15
Issue: 5
Pages: 831-40
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Publication
25190756 | J:218694
First Author: Hsieh WC
Year: 2014
Journal: Blood
Title: Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap-/- mice.
Volume: 124
Issue: 18
Pages: 2847-57
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Publication
18025200 | J:154809
First Author: Zehntner SP
Year: 2007
Journal: J Immunol
Title: X-linked inhibitor of apoptosis regulates T cell effector function.
Volume: 179
Issue: 11
Pages: 7553-60
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Publication
19956646 | J:155385
First Author: Kotevski A
Year: 2009
Journal: PLoS One
Title: Identification of an Xiap-like pseudogene on mouse chromosome 7.
Volume: 4
Issue: 11
Pages: e8078
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Publication
18755525 | J:161992
First Author: Wang J
Year: 2010
Journal: Neurobiol Aging
Title: Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice.
Volume: 31
Issue: 7
Pages: 1238-49
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Publication
21709246 | J:174393
First Author: Siegel C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia.
Volume: 108
Issue: 28
Pages: 11662-7
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Publication
20952537 | J:165092
First Author: García-Fernández M
Year: 2010
Journal: Genes Dev
Title: Sept4/ARTS is required for stem cell apoptosis and tumor suppression.
Volume: 24
Issue: 20
Pages: 2282-93
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Publication
22117219 | J:180438
First Author: Oberoi TK
Year: 2012
Journal: EMBO J
Title: IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation.
Volume: 31
Issue: 1
Pages: 14-28
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Publication
23928917 | J:207799
 
First Author: Fadó R
Year: 2013
Journal: Sci Rep
Title: X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.
Volume: 3
Pages: 2397
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Publication
18761086 | -
First Author: Winsauer G
Year: 2008
Journal: Cell Signal
Title: XIAP regulates bi-phasic NF-kappaB induction involving physical interaction and ubiquitination of MEKK2.
Volume: 20
Issue: 11
Pages: 2107-12
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Publication
32060280 | J:286733
First Author: Liao Y
Year: 2020
Journal: Nat Commun
Title: Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis.
Volume: 11
Issue: 1
Pages: 900
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Publication
17148670 | J:116222
First Author: Fessing MY
Year: 2006
Journal: Am J Pathol
Title: Involvement of the Edar signaling in the control of hair follicle involution (catagen).
Volume: 169
Issue: 6
Pages: 2075-84
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Publication
27189977 | J:239645
First Author: Gibon J
Year: 2016
Journal: FASEB J
Title: The X-linked inhibitor of apoptosis regulates long-term depression and learning rate.
Volume: 30
Issue: 9
Pages: 3083-90
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Publication
17218959 | J:139242
First Author: Vaughn AE
Year: 2007
Journal: Cell Death Differ
Title: Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons.
Volume: 14
Issue: 5
Pages: 973-81
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Publication
25292199 | J:218093
First Author: Aoto K
Year: 2015
Journal: Hum Mol Genet
Title: Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.
Volume: 24
Issue: 3
Pages: 698-713
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Publication
25056906 | J:214844
First Author: Andree M
Year: 2014
Journal: EMBO J
Title: BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.
Volume: 33
Issue: 19
Pages: 2171-87
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Publication
20932476 | J:165643
First Author: Wu ZH
Year: 2010
Journal: Mol Cell
Title: ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.
Volume: 40
Issue: 1
Pages: 75-86
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Publication
11604410 | J:182411
First Author: Verhagen AM
Year: 2002
Journal: J Biol Chem
Title: HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.
Volume: 277
Issue: 1
Pages: 445-54
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Publication
16858406 | J:200434
First Author: Kiryu-Seo S
Year: 2006
Journal: EMBO J
Title: Unique anti-apoptotic activity of EAAC1 in injured motor neurons.
Volume: 25
Issue: 14
Pages: 3411-21
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Publication
33845129 | J:307667
 
First Author: Sansa A
Year: 2021
Journal: Neurobiol Dis
Title: Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons.
Volume: 155
Pages: 105366
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Publication
22327219 | J:182515
First Author: Moulin M
Year: 2012
Journal: EMBO J
Title: IAPs limit activation of RIP kinases by TNF receptor 1 during development.
Volume: 31
Issue: 7
Pages: 1679-91
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Publication
28647349 | J:252195
First Author: Anderton H
Year: 2017
Journal: J Invest Dermatol
Title: Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.
Volume: 137
Issue: 11
Pages: 2371-2379
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Publication
12153481 | J:78107
First Author: Ishigaki S
Year: 2002
Journal: J Neurochem
Title: X-Linked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration.
Volume: 82
Issue: 3
Pages: 576-84
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Publication
19875445 | J:161686
First Author: Owens TW
Year: 2010
Journal: J Biol Chem
Title: Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.
Volume: 285
Issue: 2
Pages: 1081-8
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Publication
19735291 | J:153512
First Author: Kairisalo M
Year: 2009
Journal: Eur J Neurosci
Title: NF-kappaB-dependent regulation of brain-derived neurotrophic factor in hippocampal neurons by X-linked inhibitor of apoptosis protein.
Volume: 30
Issue: 6
Pages: 958-66
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Publication
19531477 | J:153170
First Author: Neil JR
Year: 2009
Journal: J Biol Chem
Title: X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression.
Volume: 284
Issue: 32
Pages: 21209-17
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Publication
12011074 | J:78039
First Author: Li S
Year: 2002
Journal: J Biol Chem
Title: Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis.
Volume: 277
Issue: 30
Pages: 26912-20
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Publication
31624230 | J:294981
First Author: Liu X
Year: 2019
Journal: Cell Death Dis
Title: Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development.
Volume: 10
Issue: 11
Pages: 790
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Protein Coding Gene
MGP_CAROLIEiJ_G0033024 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035674 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035643 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035347 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034638 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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