|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 187 out of 187 for Ackr2

<< First    < Previous  |  Next >    Last >>
0.031s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945886
Age: embryonic day 11.5
Image: g01906 E11.5
Specimen Label: g01906 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:7262736
Age: embryonic day 13.5
Image: S3Bi
Specimen Label: S3Bi
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:7262736
Age: embryonic day 13.5
Image: S3Bii
Specimen Label: S3Bii
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7262736
Age: embryonic day 14.5
Image: 6Bi/S3A
Specimen Label: 6Bi/S3A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7262727
Assay Type: RNA in situ
Annotation Date: 2022-04-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3187722
Stage: TS22
Assay Id: MGI:7262736
Age: embryonic day 14.5
Image: 6BII
Specimen Label: 6BII
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 7
Image: g01906 P7
Specimen Label: g01906 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 7
Image: g01906 P7
Specimen Label: g01906 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945886
Age: embryonic day 11.5
Image: g01906 E11.5
Specimen Label: g01906 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 7
Image: g01906 P7
Specimen Label: g01906 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 7
Image: g01906 P7
Specimen Label: g01906 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945886
Age: embryonic day 15.5
Image: g01906 E15.5
Specimen Label: g01906 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 7
Image: g01906 P7
Specimen Label: g01906 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945886
Age: embryonic day 15.5
Image: g01906 E15.5
Specimen Label: g01906 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945886
Age: embryonic day 15.5
Image: g01906 E15.5
Specimen Label: g01906 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 7
Image: g01906 P7
Specimen Label: g01906 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885393
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945886
Age: postnatal day 42
Image: g01906 Adult
Specimen Label: g01906 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
- | J:65071
   
First Author: Nibbs RJB
Year: 1997
Journal: GenBank Submission
Title: M. musculus mRNA for beta-chemokine receptor D6
Pages: Y12879
•
•
•
•
•
Publication
19202130 | J:148427
First Author: McKimmie CS
Year: 2009
Journal: Blood
Title: A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration.
Volume: 113
Issue: 18
Pages: 4224-31
•
•
•
•
•
Publication
24357920 | J:211852
 
First Author: Hajrasouliha AR
Year: 2013
Journal: Mol Vis
Title: Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection.
Volume: 19
Pages: 2517-25
•
•
•
•
•
Publication
14744993 | J:90891
First Author: Pabst O
Year: 2004
Journal: J Exp Med
Title: Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine.
Volume: 199
Issue: 3
Pages: 411-6
•
•
•
•
•
Publication
28674178 | J:250818
First Author: Aswad M
Year: 2017
Journal: J Immunol
Title: CCL5 Promotes Resolution-Phase Macrophage Reprogramming in Concert with the Atypical Chemokine Receptor D6 and Apoptotic Polymorphonuclear Cells.
Volume: 199
Issue: 4
Pages: 1393-1404
•
•
•
•
•
Publication
22796582 | J:201482
First Author: Cochain C
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: The chemokine decoy receptor D6 prevents excessive inflammation and adverse ventricular remodeling after myocardial infarction.
Volume: 32
Issue: 9
Pages: 2206-13
•
•
•
•
•
Publication
18714007 | J:138948
First Author: McKimmie CS
Year: 2008
Journal: J Immunol
Title: Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1.
Volume: 181
Issue: 5
Pages: 3353-63
•
•
•
•
•
Publication
22444632 | J:187035
First Author: Hadeiba H
Year: 2012
Journal: Immunity
Title: Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance.
Volume: 36
Issue: 3
Pages: 438-50
•
•
•
•
•
Publication
27680685 | J:237836
First Author: Loyher PL
Year: 2016
Journal: Cancer Res
Title: CCR2 Influences T Regulatory Cell Migration to Tumors and Serves as a Biomarker of Cyclophosphamide Sensitivity.
Volume: 76
Issue: 22
Pages: 6483-6494
•
•
•
•
•
Publication
9139699 | J:40322
First Author: Nibbs RJ
Year: 1997
Journal: J Biol Chem
Title: Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5.
Volume: 272
Issue: 19
Pages: 12495-504
•
•
•
•
•
Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
•
•
•
•
•
Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Allele
Ackr2<em1Smoc> | MGI:7288068
Name: atypical chemokine receptor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:6474714 | C57BL/6JSmoc-Ackr2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Publication
36591362 | J:344933
First Author: Zheng X
Year: 2022
Journal: Kidney360
Title: Endothelial Cell-Specific Molecule-1 Inhibits Albuminuria in Diabetic Mice.
Volume: 3
Issue: 12
Pages: 2059-2076
•
•
•
•
•
Publication
35677043 | J:325349
 
First Author: Gowhari Shabgah A
Year: 2022
Journal: Front Immunol
Title: The Role of Atypical Chemokine Receptor D6 (ACKR2) in Physiological and Pathological Conditions; Friend, Foe, or Both?
Volume: 13
Pages: 861931
•
•
•
•
•
Publication
9634238 | J:69255
First Author: Zou YR
Year: 1998
Journal: Nature
Title: Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.
Volume: 393
Issue: 6685
Pages: 595-9
•
•
•
•
•
Publication
9261420 | -
First Author: Kitchen SG
Year: 1997
Journal: J Virol
Title: CXCR4 expression during lymphopoiesis: implications for human immunodeficiency virus type 1 infection of the thymus.
Volume: 71
Issue: 9
Pages: 6928-34
•
•
•
•
•
Publication
10985313 | -
First Author: Anton PA
Year: 2000
Journal: AIDS
Title: Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue.
Volume: 14
Issue: 12
Pages: 1761-5
•
•
•
•
•
Publication
11154210 | -
First Author: Inngjerdingen M
Year: 2001
Journal: Blood
Title: Expression and regulation of chemokine receptors in human natural killer cells.
Volume: 97
Issue: 2
Pages: 367-75
•
•
•
•
•
Publication
11435493 | -
First Author: Iikura M
Year: 2001
Journal: J Leukoc Biol
Title: Chemokine receptors in human basophils: inducible expression of functional CXCR4.
Volume: 70
Issue: 1
Pages: 113-20
•
•
•
•
•
Publication
9461627 | -
First Author: Gupta SK
Year: 1998
Journal: J Biol Chem
Title: Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines.
Volume: 273
Issue: 7
Pages: 4282-7
•
•
•
•
•
Publication
11983855 | J:81783
First Author: Lu M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor.
Volume: 99
Issue: 10
Pages: 7090-5
•
•
•
•
•
Publication
18378795 | J:133973
First Author: Nie Y
Year: 2008
Journal: J Exp Med
Title: CXCR4 is required for the quiescence of primitive hematopoietic cells.
Volume: 205
Issue: 4
Pages: 777-83
•
•
•
•
•
Publication
11876757 | -
First Author: Zamarchi R
Year: 2002
Journal: Clin Exp Immunol
Title: Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes.
Volume: 127
Issue: 2
Pages: 321-30
•
•
•
•
•
Publication
12370187 | -
First Author: Sun Y
Year: 2002
Journal: J Biol Chem
Title: Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation.
Volume: 277
Issue: 51
Pages: 49212-9
•
•
•
•
•
Publication
10525044 | -
First Author: Jordan NJ
Year: 1999
Journal: J Clin Invest
Title: Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells.
Volume: 104
Issue: 8
Pages: 1061-9
•
•
•
•
•
Protein Domain
IPR001277 | CXCR4/ACKR2
Type: Family
Description: CXC chemokine receptor 4 (CXCR4), also known as fusin, which is a specific receptor for a CXCL12 (or SDF1). CXCR4 has a wide cellular distribution, with expression on most immature and mature hematopoietic cell types [, , , , ]. In addition, CXCR4 can also be found on vascular endothelial cells and neuronal/nerve cells []. Upon binding to CXCR4, CXCL12 causes mobilisation of intracellular calcium and chemotaxis [, , ]. CXCL12 is known to be important in hematopoietic stem cell homing to the bone marrow and in hematopoietic stem cell quiescence. CXCR4 has a rather broad activity, and has been linked to cardiac, cerebellar gastric vasculature development [, ]and to hematopoiesis []. Atypical chemokine receptor 2 (ACKR2/D6) []is a chemokine-scavenging receptor or chemokine decoy receptor. It is capable of internalising and effectively scavenging its ligands through beta-arrestin-dependent activation of the cofilin pathway [, ]. ACKR2 is highly promiscuous and can bin the majority of (if not all) inflammatory CC-chemokines []. It plays an essential role in the resolution of the inflammatory response [, , ]. Although it lacks the canonical DRYLAIV motif necessary for classical signalling, ACKR2/D6 may be involved in 'atypical' signaling pathways downstream of ligand binding []. It has been shown to be involved in regulating vessel density [].
•
•
•
•
•
Protein
A1E2I3
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
•
•
•
•
•
Protein
E9Q2D4
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: true
•
•
•
•
•
Publication
12055238 | -
First Author: Huber TB
Year: 2002
Journal: J Immunol
Title: Expression of functional CCR and CXCR chemokine receptors in podocytes.
Volume: 168
Issue: 12
Pages: 6244-52
•
•
•
•
•
Protein
P70658
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
•
•
•
•
•
Protein
A0A0R4J0N8
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom