Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280927 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3507929 |
Age: |
postnatal newborn |
Image: |
2 |
Note: |
The tissue was olfactory epithelium and/or bulb. |
Specimen Label: |
2 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3507929 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267927 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3507929 |
Age: |
postnatal newborn |
Image: |
2 |
|
Specimen Label: |
2 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2852723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5728 |
|
Specimen Label: |
GUDMAP:5728 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2874723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5728 |
|
Specimen Label: |
GUDMAP:5728 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2874723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:12273 |
|
Specimen Label: |
GUDMAP:12273 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757721 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3507929 |
Age: |
embryonic day 13.5 |
Image: |
1 |
|
Specimen Label: |
1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757727 |
Pattern: |
Uniform |
Stage: |
TS27 |
Assay Id: |
MGI:3507929 |
Age: |
postnatal newborn |
Image: |
2 |
Note: |
Expression was detected in all cells. |
Specimen Label: |
2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5728 |
|
Specimen Label: |
GUDMAP:5728 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2875323 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:12273 |
|
Specimen Label: |
GUDMAP:12273 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Ambiguous |
Sex: |
Female |
Emaps: |
EMAPS:2860123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:12273 |
|
Specimen Label: |
GUDMAP:12273 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539416 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5728 |
|
Specimen Label: |
GUDMAP:5728 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506406 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3817723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6513159 |
Age: |
embryonic day 15.5 |
|
Note: |
Both sexes were examined; no reproducible differences were detected between them. |
Specimen Label: |
Table 3 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Froidevaux MS |
Year: |
2006 |
Journal: |
EMBO Rep |
Title: |
The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo. |
Volume: |
7 |
Issue: |
10 |
Pages: |
1035-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Petrulis JR |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity. |
Volume: |
278 |
Issue: |
4 |
Pages: |
2677-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Oliveira SK |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor. |
Volume: |
282 |
Issue: |
18 |
Pages: |
13656-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakata A |
Year: |
2009 |
Journal: |
EMBO Rep |
Title: |
G-protein signalling negatively regulates the stability of aryl hydrocarbon receptor. |
Volume: |
10 |
Issue: |
6 |
Pages: |
622-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flaveny C |
Year: |
2009 |
Journal: |
Toxicol Lett |
Title: |
The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo. |
Volume: |
189 |
Issue: |
1 |
Pages: |
57-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marschang P |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. |
Volume: |
24 |
Issue: |
9 |
Pages: |
3782-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX Interspecific Backcross BSS and BSB Public Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Brady KP |
Year: |
1997 |
Journal: |
Genome Res |
Title: |
Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. |
Volume: |
7 |
Issue: |
11 |
Pages: |
1085-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wiese CB |
Year: |
2012 |
Journal: |
Front Neurosci |
Title: |
A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. |
Volume: |
6 |
|
Pages: |
130 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
200
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Morii H |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells. |
Volume: |
284 |
Issue: |
45 |
Pages: |
30766-74 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of archaetidylinositol phosphate synthases (AIP synthases), including MTH1691 from Methanothermobacter thermautotrophicus. AIP synthase catalyses the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate) []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Picht E |
Year: |
2007 |
Journal: |
J Mol Cell Cardiol |
Title: |
CaMKII inhibition targeted to the sarcoplasmic reticulum inhibits frequency-dependent acceleration of relaxation and Ca2+ current facilitation. |
Volume: |
42 |
Issue: |
1 |
Pages: |
196-205 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 46, John R Dedman |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Publication |
First Author: |
Akey DT |
Year: |
2002 |
Journal: |
Hum Mol Genet |
Title: |
The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1. |
Volume: |
11 |
Issue: |
22 |
Pages: |
2723-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vargiolu M |
Year: |
2009 |
Journal: |
J Clin Endocrinol Metab |
Title: |
The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability. |
Volume: |
94 |
Issue: |
7 |
Pages: |
2571-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daly AF |
Year: |
2007 |
Journal: |
J Clin Endocrinol Metab |
Title: |
Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. |
Volume: |
92 |
Issue: |
5 |
Pages: |
1891-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Proteins in this entry have an N-terminal FKBP-type peptidyl-prolyl cis-trans isomerase domain followed by a C-terminal tetratricopeptide repeat-containing domain. Included in this entry are: aryl-hydrocarbon-interacting protein-like 1 (AIPL1), which is associated with inherited blindness and interacts with cell cycle regulator protein NUB1 []; and AH receptor-interacting protein (AIP), which interacts with the tyrosine kinase receptor RET [], and mutations in AIP are associated with familial isolated pituitary adenomas []. |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, transgenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Ji Y |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Targeted inhibition of Ca2+/calmodulin-dependent protein kinase II in cardiac longitudinal sarcoplasmic reticulum results in decreased phospholamban phosphorylation at threonine 17. |
Volume: |
278 |
Issue: |
27 |
Pages: |
25063-71 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(Myh6-AIP/PLN*)46Jded/? |
Background: |
FVB/N-Tg(Myh6-AIP/PLN*)46Jded |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Meagher C |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Spontaneous development of a pancreatic exocrine disease in CD28-deficient NOD mice. |
Volume: |
180 |
Issue: |
12 |
Pages: |
7793-803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade. |
Volume: |
37 |
Issue: |
8 |
Pages: |
110021 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lindberg RL |
Year: |
1996 |
Journal: |
Nat Genet |
Title: |
Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria. |
Volume: |
12 |
Issue: |
2 |
Pages: |
195-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Q |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon. |
Volume: |
290 |
Issue: |
23 |
Pages: |
14729-39 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
179
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Dufour P |
Year: |
2002 |
Journal: |
J Bacteriol |
Title: |
High genetic variability of the agr locus in Staphylococcus species. |
Volume: |
184 |
Issue: |
4 |
Pages: |
1180-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Members of this family of short peptides are precursors to thiolactone (unless Cys is replaced by Ser) cyclic autoinducer peptides, used in quorum-sensing systems in Gram-positive bacteria. The best characterised is the AgrD precursor, processed by the AgrB protein. Nearby proteins regularly encountered include a histidine kinase and a response regulator. The agr locus was initially described in Staphylococcus aureus as an element controlling the production of exoproteins implicated in virulence. Its pattern of action has been shown to be complex, upregulating certain extracellular toxins and enzymes expressed post-exponentially and repressing some exponential-phase surface components. AgrD encodes the precursor of the autoinducing peptide (AIP).The AIP derived from AgrD by the action of AgrB interacts with AgrC in the membrane to activate AgrA, which upregulates transcription both from promoter P2, amplifying the response, and from P3, initiating the production of a novel effector: RNAIII. In S. aureus, delta-hemolysin is the only translation product of RNA III and is not involved in the regulatory functions of the transcript, which is therefore the primary agent for modulating the expression of other operons controlled by agr []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Seleznik GM |
Year: |
2018 |
Journal: |
Gut |
Title: |
Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation. |
Volume: |
67 |
Issue: |
9 |
Pages: |
1663-1673 |
|
•
•
•
•
•
|
Publication |
First Author: |
Louis C |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System. |
Volume: |
195 |
Issue: |
1 |
Pages: |
134-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Uemura M |
Year: |
2010 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis. |
Volume: |
391 |
Issue: |
1 |
Pages: |
357-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Homedan C |
Year: |
2015 |
Journal: |
Hum Mol Genet |
Title: |
Mitochondrial energetic defects in muscle and brain of a Hmbs-/- mouse model of acute intermittent porphyria. |
Volume: |
24 |
Issue: |
17 |
Pages: |
5015-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Unzu C |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice. |
Volume: |
22 |
Issue: |
14 |
Pages: |
2929-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Unzu C |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse. |
Volume: |
7 |
Issue: |
3 |
Pages: |
e32978 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yasuda M |
Year: |
2019 |
Journal: |
Hum Mol Genet |
Title: |
Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria. |
Volume: |
28 |
Issue: |
11 |
Pages: |
1755-1767 |
|
•
•
•
•
•
|
Publication |
First Author: |
Longo M |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
Nutritional Interventions with Bacillus coagulans Improved Glucose Metabolism and Hyperinsulinemia in Mice with Acute Intermittent Porphyria. |
Volume: |
24 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Collantes M |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Glucose metabolism during fasting is altered in experimental porphobilinogen deaminase deficiency. |
Volume: |
25 |
Issue: |
7 |
Pages: |
1318-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansson A |
Year: |
2003 |
Journal: |
Mol Med |
Title: |
Biochemical characterization of porphobilinogen deaminase-deficient mice during phenobarbital induction of heme synthesis and the effect of enzyme replacement. |
Volume: |
9 |
Issue: |
9-12 |
Pages: |
193-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boomershine CS |
Year: |
2009 |
Journal: |
Gut |
Title: |
Autoimmune pancreatitis results from loss of TGFbeta signalling in S100A4-positive dendritic cells. |
Volume: |
58 |
Issue: |
9 |
Pages: |
1267-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiang DY |
Year: |
2014 |
Journal: |
Cardiovasc Res |
Title: |
Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. |
Volume: |
103 |
Issue: |
1 |
Pages: |
178-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broersen R |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Synaptic mechanisms for associative learning in the cerebellar nuclei. |
Volume: |
14 |
Issue: |
1 |
Pages: |
7459 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wagner S |
Year: |
2011 |
Journal: |
Circ Res |
Title: |
Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload. |
Volume: |
108 |
Issue: |
5 |
Pages: |
555-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukuhara T |
Year: |
2015 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Hypermethylation of MST1 in IgG4-related autoimmune pancreatitis and rheumatoid arthritis. |
Volume: |
463 |
Issue: |
4 |
Pages: |
968-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berger S |
Year: |
2020 |
Journal: |
Acta Neuropathol Commun |
Title: |
Severe hydroxymethylbilane synthase deficiency causes depression-like behavior and mitochondrial dysfunction in a mouse model of homozygous dominant acute intermittent porphyria. |
Volume: |
8 |
Issue: |
1 |
Pages: |
38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kiat LS |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Aurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinase. |
Volume: |
277 |
Issue: |
47 |
Pages: |
45558-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li B |
Year: |
2006 |
Journal: |
Biochim Biophys Acta |
Title: |
Nuclear Ca2+/calmodulin-dependent protein kinase II in the murine heart. |
Volume: |
1763 |
Issue: |
11 |
Pages: |
1275-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Camoriano M |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
Phenotype-specific CpG island methylation events in a murine model of prostate cancer. |
Volume: |
68 |
Issue: |
11 |
Pages: |
4173-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asghari F |
Year: |
2011 |
Journal: |
J Med Genet |
Title: |
Identification of quantitative trait loci for murine autoimmune pancreatitis. |
Volume: |
48 |
Issue: |
8 |
Pages: |
557-62 |
|
•
•
•
•
•
|