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Search results 101 to 200 out of 767 for Aire

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274122
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666383
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1776322
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666383
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1776322
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666384
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1609217
Stage: TS17
Assay Id: MGI:2666383
Age: embryonic day 10.5
Image: Aire 10.5dpc
Specimen Label: Aire 10.5dpc
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1609217
Stage: TS17
Assay Id: MGI:2666384
Age: embryonic day 10.5
Image: Aire 10.5dpc
Specimen Label: Aire 10.5dpc
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666383
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666384
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666917
Stage: TS17
Assay Id: MGI:2666383
Age: embryonic day 10.5
Image: Aire 10.5dpc
Specimen Label: Aire 10.5dpc
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1611717
Stage: TS17
Assay Id: MGI:2666384
Age: embryonic day 10.5
Image: Aire 10.5dpc
Specimen Label: Aire 10.5dpc
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666383
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666384
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666384
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666383
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666383
Age: embryonic day 10.5
Image: Aire 10.5dpc
Specimen Label: Aire 10.5dpc
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666384
Age: embryonic day 10.5
Image: Aire 10.5dpc
Specimen Label: Aire 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796222
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666383
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:674349
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796222
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666384
Age: embryonic day 14.5
Image: Aire 14.5dpc
Specimen Label: Aire 14.5dpc
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:6725771
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3801528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6725788
Age: postnatal week 6
Image: 1H AIRE
Note: Expression in medullary thymic epithelial cells.
Specimen Label: 1H AIRE
Specimen Num: 1
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Protein
D6RDQ5
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: false
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GXD Expression
GXD Expression
   
Probe: MGI:6725771
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3801528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6725788
Age: postnatal week 4
Image: 3I -4OHT AIRE
Specimen Label: 3I -4OHT AIRE
Specimen Num: 3
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Protein
E9Q441
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
Q9Z0E3
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
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Protein
Q3ZB65
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
B2MVU6
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
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Publication
36231130 | J:330170
 
First Author: Petrusová J
Year: 2022
Journal: Cells
Title: AIRE in Male Fertility: A New Hypothesis.
Volume: 11
Issue: 19
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Publication
25157574 | J:221079
First Author: Nakajima A
Year: 2014
Journal: PLoS One
Title: Commensal bacteria regulate thymic Aire expression.
Volume: 9
Issue: 8
Pages: e105904
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Publication
26237550 | J:233101
First Author: Meredith M
Year: 2015
Journal: Nat Immunol
Title: Aire controls gene expression in the thymic epithelium with ordered stochasticity.
Volume: 16
Issue: 9
Pages: 942-9
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Publication
19011083 | J:142232
First Author: Lindh E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: AIRE regulates T-cell-independent B-cell responses through BAFF.
Volume: 105
Issue: 47
Pages: 18466-71
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Publication
12612579 | J:128567
First Author: Liston A
Year: 2003
Journal: Nat Immunol
Title: Aire regulates negative selection of organ-specific T cells.
Volume: 4
Issue: 4
Pages: 350-4
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Publication
26503950 | J:311532
First Author: Kawano H
Year: 2015
Journal: J Immunol
Title: Aire Expression Is Inherent to Most Medullary Thymic Epithelial Cells during Their Differentiation Program.
Volume: 195
Issue: 11
Pages: 5149-58
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Publication
16172259 | J:107432
First Author: Jiang W
Year: 2005
Journal: J Exp Med
Title: Modifier loci condition autoimmunity provoked by Aire deficiency.
Volume: 202
Issue: 6
Pages: 805-15
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GXD Expression
GXD Expression
 
Probe: MGI:668109
Assay Type: RNA in situ
Annotation Date: 2003-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:2674634
Age: embryonic day 9.5
Note: The expression was widespread.
Specimen Label: Aire 9.5dpc
Detected: true
Specimen Num: 1
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Publication
23370329 | J:196876
First Author: Zhu ML
Year: 2013
Journal: Cancer Res
Title: Aire deficiency promotes TRP-1-specific immune rejection of melanoma.
Volume: 73
Issue: 7
Pages: 2104-16
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Publication
34930780 | J:331501
First Author: Nishijima H
Year: 2022
Journal: J Immunol
Title: Aire Controls Heterogeneity of Medullary Thymic Epithelial Cells for the Expression of Self-Antigens.
Volume: 208
Issue: 2
Pages: 303-320
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Publication
16111640 | J:100515
First Author: Anderson MS
Year: 2005
Journal: Immunity
Title: The cellular mechanism of Aire control of T cell tolerance.
Volume: 23
Issue: 2
Pages: 227-39
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Publication
26999605 | J:234710
First Author: Dragin N
Year: 2016
Journal: J Clin Invest
Title: Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.
Volume: 126
Issue: 4
Pages: 1525-37
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Publication
22540148 | J:320323
First Author: Bin G
Year: 2012
Journal: Stem Cells Dev
Title: Aire promotes the self-renewal of embryonic stem cells through Lin28.
Volume: 21
Issue: 15
Pages: 2878-90
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Publication
18083234 | J:131642
First Author: Ilmarinen T
Year: 2008
Journal: Mol Immunol
Title: Functional interaction of AIRE with PIAS1 in transcriptional regulation.
Volume: 45
Issue: 7
Pages: 1847-62
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Publication
18780794 | J:139073
First Author: Guerau-de-Arellano M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional impact of Aire varies with cell type.
Volume: 105
Issue: 37
Pages: 14011-6
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Publication
28742026 | J:242967
   
First Author: Gu B
Year: 2017
Journal: Elife
Title: AIRE is a critical spindle-associated protein in embryonic stem cells.
Volume: 6
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Publication
24464130 | J:209441
First Author: Waterfield M
Year: 2014
Journal: Nat Immunol
Title: The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.
Volume: 15
Issue: 3
Pages: 258-65
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Publication
20615959 | J:162311
First Author: Koh AS
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
Volume: 107
Issue: 29
Pages: 13016-21
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Publication
17599412 | J:124288
First Author: Kont V
Year: 2008
Journal: Mol Immunol
Title: Modulation of Aire regulates the expression of tissue-restricted antigens.
Volume: 45
Issue: 1
Pages: 25-33
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Publication
12376594 | J:83422
First Author: Anderson MS
Year: 2002
Journal: Science
Title: Projection of an immunological self shadow within the thymus by the aire protein.
Volume: 298
Issue: 5597
Pages: 1395-401
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Publication
24516201 | J:209922
First Author: Nishikawa Y
Year: 2014
Journal: J Immunol
Title: Temporal lineage tracing of Aire-expressing cells reveals a requirement for Aire in their maturation program.
Volume: 192
Issue: 6
Pages: 2585-92
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Publication
27851927 | J:259743
First Author: Fujikado N
Year: 2016
Journal: Immunity
Title: Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.
Volume: 45
Issue: 5
Pages: 999-1012
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Publication
31023489 | J:289197
First Author: Huo F
Year: 2019
Journal: Immunobiology
Title: Aire deficient dendritic cells promote the T follicular helper cells differentiation.
Volume: 224
Issue: 4
Pages: 539-550
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Publication
29193031 | J:258694
First Author: Dobeš J
Year: 2018
Journal: Eur J Immunol
Title: A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.
Volume: 48
Issue: 3
Pages: 546-548
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Publication
18209027 | J:131354
First Author: Schaller CE
Year: 2008
Journal: J Immunol
Title: Expression of Aire and the early wave of apoptosis in spermatogenesis.
Volume: 180
Issue: 3
Pages: 1338-43
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Publication
19487417 | J:149510
First Author: Guerau-de-Arellano M
Year: 2009
Journal: J Exp Med
Title: Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity.
Volume: 206
Issue: 6
Pages: 1245-52
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Publication
36270546 | J:332080
     
First Author: Maglakelidze N
Year: 2022
Journal: J Invest Dermatol
Title: AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice.
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Publication
20404099 | J:160217
First Author: Nishikawa Y
Year: 2010
Journal: J Exp Med
Title: Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation.
Volume: 207
Issue: 5
Pages: 963-71
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Publication
26168014 | J:231848
First Author: Hobbs RP
Year: 2015
Journal: Nat Genet
Title: Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes.
Volume: 47
Issue: 8
Pages: 933-8
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Publication
10022980 | J:53196
First Author: Blechschmidt K
Year: 1999
Journal: Genome Res
Title: The mouse Aire gene: comparative genomic sequencing, gene organization, and expression.
Volume: 9
Issue: 2
Pages: 158-66
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Publication
35172142 | J:320898
First Author: Morimoto J
Year: 2022
Journal: Cell Rep
Title: Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity.
Volume: 38
Issue: 7
Pages: 110384
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Publication
29335648 | J:282640
First Author: Koh AS
Year: 2018
Journal: Nat Immunol
Title: Rapid chromatin repression by Aire provides precise control of immune tolerance.
Volume: 19
Issue: 2
Pages: 162-172
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Publication
11854172 | J:77873
First Author: Ramsey C
Year: 2002
Journal: Hum Mol Genet
Title: Aire deficient mice develop multiple features of APECED phenotype and show altered immune response.
Volume: 11
Issue: 4
Pages: 397-409
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Publication
26364592 | J:233730
First Author: Haljasorg U
Year: 2015
Journal: Eur J Immunol
Title: A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice.
Volume: 45
Issue: 12
Pages: 3246-56
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Publication
17947641 | J:153012
First Author: Venanzi ES
Year: 2007
Journal: J Immunol
Title: Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected.
Volume: 179
Issue: 9
Pages: 5693-700
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Publication
15492124 | J:93912
First Author: Liston A
Year: 2004
Journal: J Exp Med
Title: Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.
Volume: 200
Issue: 8
Pages: 1015-26
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Publication
32547551 | J:308185
 
First Author: Oliveira EH
Year: 2020
Journal: Front Immunol
Title: Aire Gene Influences the Length of the 3' UTR of mRNAs in Medullary Thymic Epithelial Cells.
Volume: 11
Pages: 1039
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Publication
19744957 | J:154313
First Author: Org T
Year: 2009
Journal: Hum Mol Genet
Title: AIRE activated tissue specific genes have histone modifications associated with inactive chromatin.
Volume: 18
Issue: 24
Pages: 4699-710
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Publication
20483761 | J:161141
First Author: Daniely D
Year: 2010
Journal: J Immunol
Title: Diversity of TCRs on natural Foxp3+ T cells in mice lacking Aire expression.
Volume: 184
Issue: 12
Pages: 6865-73
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Publication
16820279 | J:114934
First Author: Pöntynen N
Year: 2006
Journal: J Autoimmun
Title: Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients.
Volume: 27
Issue: 2
Pages: 96-104
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Publication
17312146 | J:144101
First Author: Gillard GO
Year: 2007
Journal: J Immunol
Title: Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.
Volume: 178
Issue: 5
Pages: 3007-15
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Publication
22203960 | J:179981
First Author: Giraud M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells.
Volume: 109
Issue: 2
Pages: 535-40
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Publication
16628255 | J:108949
First Author: Niki S
Year: 2006
Journal: J Clin Invest
Title: Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.
Volume: 116
Issue: 5
Pages: 1292-301
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Publication
21505196 | J:176949
First Author: Hubert FX
Year: 2011
Journal: Blood
Title: Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.
Volume: 118
Issue: 9
Pages: 2462-72
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Publication
17277780 | J:118669
First Author: Hamazaki Y
Year: 2007
Journal: Nat Immunol
Title: Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.
Volume: 8
Issue: 3
Pages: 304-11
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Publication
36409920 | J:335884
First Author: Michelson DA
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: CTLA-4 on thymic epithelial cells complements Aire for T cell central tolerance.
Volume: 119
Issue: 48
Pages: e2215474119
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Publication
27130899 | J:254633
First Author: Malchow S
Year: 2016
Journal: Immunity
Title: Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage.
Volume: 44
Issue: 5
Pages: 1102-13
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Publication
29285761 | J:262956
First Author: Cowan JE
Year: 2018
Journal: Eur J Immunol
Title: Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.
Volume: 48
Issue: 5
Pages: 844-854
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Publication
16982213 | J:115940
First Author: Brännström J
Year: 2006
Journal: Clin Immunol
Title: Defect internalization and tyrosine kinase activation in Aire deficient antigen presenting cells exposed to Candida albicans antigens.
Volume: 121
Issue: 3
Pages: 265-73
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Publication
19234163 | J:146261
First Author: Fletcher AL
Year: 2009
Journal: J Immunol
Title: Reduced thymic Aire expression and abnormal NF-kappa B2 signaling in a model of systemic autoimmunity.
Volume: 182
Issue: 5
Pages: 2690-9
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Publication
17938200 | J:130071
First Author: Oven I
Year: 2007
Journal: Mol Cell Biol
Title: AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells.
Volume: 27
Issue: 24
Pages: 8815-23
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Publication
35061506 | J:360937
First Author: Heinlein M
Year: 2022
Journal: Sci Immunol
Title: The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance.
Volume: 7
Issue: 67
Pages: eabb6032
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Publication
18322189 | J:133033
First Author: Hubert FX
Year: 2008
Journal: J Immunol
Title: A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery.
Volume: 180
Issue: 6
Pages: 3824-32
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•
•
•
•
Publication
25224068 | J:274436
First Author: Sansom SN
Year: 2014
Journal: Genome Res
Title: Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.
Volume: 24
Issue: 12
Pages: 1918-31
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•
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•
Publication
29101311 | J:252604
First Author: Mouri Y
Year: 2017
Journal: J Immunol
Title: Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen.
Volume: 199
Issue: 12
Pages: 3959-3971
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•
•
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•
Publication
10925280 | J:63747
First Author: Zuklys S
Year: 2000
Journal: J Immunol
Title: Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Volume: 165
Issue: 4
Pages: 1976-83
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Publication
19015306 | J:141379
First Author: Yano M
Year: 2008
Journal: J Exp Med
Title: Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
Volume: 205
Issue: 12
Pages: 2827-38
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•
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Publication
23487421 | J:194890
First Author: Zeng XL
Year: 2013
Journal: J Immunol
Title: Divergent effects of T cell costimulation and inflammatory cytokine production on autoimmune peripheral neuropathy provoked by Aire deficiency.
Volume: 190
Issue: 8
Pages: 3895-904
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Publication
26216992 | J:226509
First Author: Yoshida H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells.
Volume: 112
Issue: 32
Pages: E4448-57
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Publication
34518235 | J:310704
 
First Author: Bansal K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on superenhancers.
Volume: 118
Issue: 38
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Publication
24434558 | J:206446
First Author: Giraud M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.
Volume: 111
Issue: 4
Pages: 1491-6
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Publication
23041971 | J:191104
First Author: Danso-Abeam D
Year: 2013
Journal: Eur J Immunol
Title: Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism.
Volume: 43
Issue: 1
Pages: 75-84
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Publication
19264867 | J:158187
First Author: Misharin AV
Year: 2009
Journal: Endocrinology
Title: Studies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigens.
Volume: 150
Issue: 6
Pages: 2948-56
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Publication
38261611 | J:360275
First Author: Yin M
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model.
Volume: 121
Issue: 5
Pages: e2311487121
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GXD Expression
GXD Expression
 
Probe: MGI:7714906
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3801528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7715225
Age: postnatal adult
Note: Aire staining in mature medullary thymic epithelial cells co-localizes with Krt5, a medullary thymic epithelial cell marker, in those cells.
Specimen Label: 3A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7714906
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3801528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7715225
Age: postnatal adult
Note: Aire staining in mature medullary thymic epithelial cells co-localizes with Krt5, a medullary thymic epithelial cell marker, in those cells.
Specimen Label: 3B WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7714906
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3801528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7715225
Age: postnatal adult
Note: Aire staining in mature medullary thymic epithelial cells was significantly decreased in the mutant compared with wild type.
Specimen Label: 3B RANKL-/-
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7714906
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3801528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7715225
Age: postnatal adult
Note: Aire localized in mature medullary thymic epithelial cells. Expression was observed in a vesicle- like localization in the nucleus that colocalized with the Tbata protein.
Specimen Label: 2C
Detected: true
Specimen Num: 1
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Publication
32845012 | J:302285
First Author: Ferreirinha P
Year: 2021
Journal: Eur J Immunol
Title: A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation.
Volume: 51
Issue: 2
Pages: 311-318
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GXD Expression
GXD Expression
   
Probe: MGI:6725772
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3801428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6725790
Age: postnatal week 4
Image: 3I -4OHT AIRE
Specimen Label: 3I -4OHT AIRE
Specimen Num: 3
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Publication
25791085 | J:221494
First Author: Yang S
Year: 2015
Journal: Science
Title: Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.
Volume: 348
Issue: 6234
Pages: 589-94
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Publication
26006015 | J:259140
First Author: Chuprin A
Year: 2015
Journal: Nat Immunol
Title: The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.
Volume: 16
Issue: 7
Pages: 737-45
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Publication
18687966 | J:154359
First Author: Gardner JM
Year: 2008
Journal: Science
Title: Deletional tolerance mediated by extrathymic Aire-expressing cells.
Volume: 321
Issue: 5890
Pages: 843-7
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Publication
27941786 | J:260180
First Author: Herzig Y
Year: 2017
Journal: Nat Immunol
Title: Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Volume: 18
Issue: 2
Pages: 161-172
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Publication
10049587 | J:53197
First Author: Wang CY
Year: 1999
Journal: Genomics
Title: Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome type 1 (ASP1).
Volume: 55
Issue: 3
Pages: 322-6
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Publication
17513766 | J:147835
First Author: Ruan QG
Year: 2007
Journal: J Immunol
Title: The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function.
Volume: 178
Issue: 11
Pages: 7173-80
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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