Type |
Details |
Score |
Publication |
First Author: |
Feldmann A |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7. |
Volume: |
31 |
Issue: |
15 |
Pages: |
5659-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salazar G |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells. |
Volume: |
279 |
Issue: |
24 |
Pages: |
25430-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salazar G |
Year: |
2005 |
Journal: |
J Cell Sci |
Title: |
Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc stores in PC12 cells. |
Volume: |
118 |
Issue: |
Pt 9 |
Pages: |
1911-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Newell-Litwa K |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus. |
Volume: |
30 |
Issue: |
3 |
Pages: |
820-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasai M |
Year: |
2010 |
Journal: |
Science |
Title: |
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. |
Volume: |
329 |
Issue: |
5998 |
Pages: |
1530-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Theos AC |
Year: |
2005 |
Journal: |
Mol Biol Cell |
Title: |
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. |
Volume: |
16 |
Issue: |
11 |
Pages: |
5356-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muthusamy N |
Year: |
2012 |
Journal: |
J Neurochem |
Title: |
Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes. |
Volume: |
123 |
Issue: |
1 |
Pages: |
60-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simpson F |
Year: |
1997 |
Journal: |
J Cell Biol |
Title: |
Characterization of the adaptor-related protein complex, AP-3. |
Volume: |
137 |
Issue: |
4 |
Pages: |
835-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charles CH |
Year: |
1992 |
Journal: |
Oncogene |
Title: |
cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. |
Volume: |
7 |
Issue: |
1 |
Pages: |
187-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gokhale A |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1. |
Volume: |
32 |
Issue: |
11 |
Pages: |
3697-711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Swank RT |
Year: |
1998 |
Journal: |
Pigment Cell Res |
Title: |
Mouse models of Hermansky Pudlak syndrome: a review. |
Volume: |
11 |
Issue: |
2 |
Pages: |
60-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Swank RT |
Year: |
2000 |
Journal: |
Pigment Cell Res |
Title: |
Abnormal vesicular trafficking in mouse models of Hermansky-Pudlak syndrome. |
Volume: |
13 Suppl 8 |
|
Pages: |
59-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elewaut D |
Year: |
2003 |
Journal: |
J Exp Med |
Title: |
The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. |
Volume: |
198 |
Issue: |
8 |
Pages: |
1133-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Misawa H |
Year: |
2008 |
Journal: |
Eur J Neurosci |
Title: |
Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice. |
Volume: |
27 |
Issue: |
12 |
Pages: |
3109-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu H |
Year: |
2023 |
Journal: |
Nat Neurosci |
Title: |
Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1. |
Volume: |
26 |
Issue: |
10 |
Pages: |
1685-1700 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jain S |
Year: |
2023 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Adaptor protein-3 produces synaptic vesicles that release phasic dopamine. |
Volume: |
120 |
Issue: |
42 |
Pages: |
e2309843120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsuda S |
Year: |
2013 |
Journal: |
Nat Commun |
Title: |
Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression. |
Volume: |
4 |
|
Pages: |
2759 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dell'Angelica EC |
Year: |
1998 |
Journal: |
Science |
Title: |
Association of the AP-3 adaptor complex with clathrin. |
Volume: |
280 |
Issue: |
5362 |
Pages: |
431-4 |
|
•
•
•
•
•
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Publication |
First Author: |
Barclay J |
Year: |
1999 |
Journal: |
Epilepsia |
Title: |
Mouse models of spike-wave epilepsy. |
Volume: |
40 Suppl 3 |
|
Pages: |
17-22 |
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•
•
•
•
•
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Publication |
First Author: |
Friocourt G |
Year: |
2001 |
Journal: |
Mol Cell Neurosci |
Title: |
Doublecortin interacts with mu subunits of clathrin adaptor complexes in the developing nervous system. |
Volume: |
18 |
Issue: |
3 |
Pages: |
307-19 |
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•
•
•
•
•
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Publication |
First Author: |
Salazar G |
Year: |
2006 |
Journal: |
Mol Biol Cell |
Title: |
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. |
Volume: |
17 |
Issue: |
9 |
Pages: |
4014-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salazar G |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. |
Volume: |
284 |
Issue: |
3 |
Pages: |
1790-802 |
|
•
•
•
•
•
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Publication |
First Author: |
Kapfhamer D |
Year: |
1994 |
Journal: |
Genomics |
Title: |
Genetic map of the region around grizzled (gr) and mocha (mh) on mouse chromosome 10, homologous to human 19p13.3. |
Volume: |
23 |
Issue: |
3 |
Pages: |
635-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Concepcion D |
Year: |
2009 |
Journal: |
PLoS Genet |
Title: |
Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing. |
Volume: |
5 |
Issue: |
5 |
Pages: |
e1000484 |
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•
•
•
•
•
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Publication |
First Author: |
Swank RT |
Year: |
1991 |
Journal: |
Blood |
Title: |
Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha. |
Volume: |
78 |
Issue: |
8 |
Pages: |
2036-44 |
|
•
•
•
•
•
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Publication |
First Author: |
Newell-Litwa K |
Year: |
2009 |
Journal: |
Mol Biol Cell |
Title: |
Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles. |
Volume: |
20 |
Issue: |
5 |
Pages: |
1441-53 |
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•
•
•
•
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Publication |
First Author: |
Bultema JJ |
Year: |
2013 |
Journal: |
Small GTPases |
Title: |
Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles. |
Volume: |
4 |
Issue: |
1 |
Pages: |
16-21 |
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Publication |
First Author: |
Larimore J |
Year: |
2011 |
Journal: |
Mol Biol Cell |
Title: |
The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse. |
Volume: |
22 |
Issue: |
24 |
Pages: |
4854-67 |
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Publication |
First Author: |
Meisler MH |
Year: |
2001 |
Journal: |
Annu Rev Genet |
Title: |
Identification of epilepsy genes in human and mouse. |
Volume: |
35 |
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Pages: |
567-88 |
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Publication |
First Author: |
Odorizzi G |
Year: |
1998 |
Journal: |
Trends Cell Biol |
Title: |
The AP-3 complex: a coat of many colours. |
Volume: |
8 |
Issue: |
7 |
Pages: |
282-8 |
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Publication |
First Author: |
Jones SM |
Year: |
2005 |
Journal: |
J Assoc Res Otolaryngol |
Title: |
A quantitative survey of gravity receptor function in mutant mouse strains. |
Volume: |
6 |
Issue: |
4 |
Pages: |
297-310 |
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Publication |
First Author: |
Puttagunta R |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints. |
Volume: |
10 |
Issue: |
9 |
Pages: |
1369-80 |
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•
•
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•
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Publication |
First Author: |
Silvers WK |
Year: |
1979 |
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Title: |
The Coat Colors of Mice; A Model for Mammalian Gene Action and Interaction |
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Publication |
First Author: |
Fairfield H |
Year: |
2015 |
Journal: |
Genome Res |
Title: |
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. |
Volume: |
25 |
Issue: |
7 |
Pages: |
948-57 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
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Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
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Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
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•
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Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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•
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•
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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•
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Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
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4 |
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e86 |
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First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
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Pages: |
14109-14 |
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First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
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Cyagen Biosciences Website. |
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First Author: |
GOA curators |
Year: |
2016 |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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First Author: |
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Year: |
2011 |
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PLoS Biol |
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
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Mouse Genome Informatics Scientific Curators |
Year: |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
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Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
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Journal: |
Database Release |
Title: |
Entrez Gene Load |
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First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
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Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
UniProt Feature |
Begin: |
253 |
Description: |
Lysosomal targeting motif. Required for AP1G1, AP2A2 and AP3D1 interaction |
Type: |
short sequence motif |
End: |
254 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishimura N |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The delta subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surface. |
Volume: |
99 |
Issue: |
10 |
Pages: |
6755-60 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
AP-3 complex subunit delta-1 (AP3D1) is part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. AP3D1 is required for efficient transport of VSV-G (vesicular stomatitis virus glycoprotein) from the trans-Golgi network to the cell surface [].This entry represents the AP-3 complex subunit delta domain found in metazoa. |
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•
•
•
•
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Publication |
First Author: |
Du W |
Year: |
2021 |
Journal: |
Cancer Discov |
Title: |
Loss of optineurin drives cancer immune evasion via palmitoylation-dependent IFNGR1 lysosomal sorting and degradation. |
|
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|
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The adaptor protein complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Adaptor protein complex 3 (AP-3) appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. AP-3 is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2). The subunits of non-clathrin- and clathrin-associated adaptor protein complex 3 play a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or in endosomes. This group represents an adaptor protein complex AP-3, delta subunit. |
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•
•
•
•
•
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Publication |
First Author: |
Hildyard JCW |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy. |
Volume: |
14 |
Issue: |
1 |
Pages: |
e0211384 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1199
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
841
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
740
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
162
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
122
 |
Fragment?: |
true |
|
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•
•
•
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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