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Search results 101 to 200 out of 4757 for Apoe

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Type Details Score
Publication
10479659 | J:59495
First Author: Tsukamoto K
Year: 1999
Journal: Arterioscler Thromb Vasc Biol
Title: Rapid regression of atherosclerosis induced by liver-directed gene transfer of ApoE in ApoE-deficient mice.
Volume: 19
Issue: 9
Pages: 2162-70
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Publication
19474305 | J:149522
First Author: Bales KR
Year: 2009
Journal: J Neurosci
Title: Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice.
Volume: 29
Issue: 21
Pages: 6771-9
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Publication
31972218 | J:293248
First Author: Li Y
Year: 2020
Journal: Exp Cell Res
Title: VX-765 attenuates atherosclerosis in ApoE deficient mice by modulating VSMCs pyroptosis.
Volume: 389
Issue: 1
Pages: 111847
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Publication
10669641 | J:60479
First Author: Desurmont C
Year: 2000
Journal: Arterioscler Thromb Vasc Biol
Title: Complete atherosclerosis regression after human ApoE gene transfer in ApoE-deficient/nude mice.
Volume: 20
Issue: 2
Pages: 435-42
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Publication
20547867 | J:161364
First Author: Chen Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling.
Volume: 107
Issue: 26
Pages: 12011-6
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Publication
32152337 | J:292856
First Author: Area-Gomez E
Year: 2020
Journal: Sci Rep
Title: APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice.
Volume: 10
Issue: 1
Pages: 4277
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Publication
36688151 | J:332839
 
First Author: Huguenard CJC
Year: 2022
Journal: Front Aging Neurosci
Title: Age and APOE affect L-carnitine system metabolites in the brain in the APOE-TR model.
Volume: 14
Pages: 1059017
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Publication
14507923 | J:86768
First Author: Lynch JR
Year: 2003
Journal: J Biol Chem
Title: APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response.
Volume: 278
Issue: 49
Pages: 48529-33
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Publication
35783454 | J:341567
First Author: Foley KE
Year: 2022
Journal: Alzheimers Dement (N Y)
Title: APOE ε4 and exercise interact in a sex-specific manner to modulate dementia risk factors.
Volume: 8
Issue: 1
Pages: e12308
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Publication
35915083 | J:351105
First Author: Zhang H
Year: 2022
Journal: Signal Transduct Target Ther
Title: APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients.
Volume: 7
Issue: 1
Pages: 261
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Publication
30711612 | J:276052
 
First Author: Muza P
Year: 2019
Journal: Neuroscience
Title: APOE Genotype Specific Effects on the Early Neurodegenerative Sequelae Following Chronic Repeated Mild Traumatic Brain Injury.
Volume: 404
Pages: 297-313
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Publication
37944881 | J:350360
 
First Author: Demby T
Year: 2024
Journal: Exp Neurol
Title: The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype.
Volume: 371
Pages: 114609
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Publication
37824329 | J:342177
First Author: Phu TA
Year: 2023
Journal: Cell Rep
Title: ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia.
Volume: 42
Issue: 10
Pages: 113206
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Publication
15708438 | J:101973
First Author: Robertson J
Year: 2005
Journal: Neurobiol Aging
Title: apoE isoforms and measures of anxiety in probable AD patients and Apoe-/- mice.
Volume: 26
Issue: 5
Pages: 637-43
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Publication
36871219 | J:337495
First Author: Lee S
Year: 2023
Journal: Cell Rep
Title: APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge.
Volume: 42
Issue: 3
Pages: 112196
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Publication
21839726 | J:176065
First Author: Mukhamedova N
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Global functional knockdown of ATP binding cassette transporter A1 stimulates development of atherosclerosis in apoE K/O mice.
Volume: 412
Issue: 3
Pages: 446-9
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Publication
22940439 | J:190021
First Author: Fang G
Year: 2012
Journal: Am J Pathol
Title: Chronic intermittent hypoxia exposure induces atherosclerosis in ApoE knockout mice: role of NF-κB p50.
Volume: 181
Issue: 5
Pages: 1530-9
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Publication
12364544 | J:79439
First Author: Fazio S
Year: 2002
Journal: J Lipid Res
Title: Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice.
Volume: 43
Issue: 10
Pages: 1602-9
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Publication
25870274 | J:325919
First Author: Toledo A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia.
Volume: 112
Issue: 17
Pages: 5491-6
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Publication
16339113 | J:107556
First Author: Kypreos KE
Year: 2006
Journal: J Lipid Res
Title: LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mice.
Volume: 47
Issue: 3
Pages: 521-9
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Publication
27559087 | J:235583
First Author: Chung WS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes.
Volume: 113
Issue: 36
Pages: 10186-91
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Publication
12609489 | J:126223
First Author: Ophir G
Year: 2003
Journal: Neurobiol Dis
Title: Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice.
Volume: 12
Issue: 1
Pages: 56-64
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Publication
21659554 | J:175567
First Author: Huebbe P
Year: 2011
Journal: FASEB J
Title: APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans.
Volume: 25
Issue: 9
Pages: 3262-70
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Publication
22735491 | J:187179
First Author: Reverte I
Year: 2012
Journal: Exp Neurol
Title: Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice.
Volume: 237
Issue: 1
Pages: 116-25
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Publication
33597265 | J:304463
 
First Author: Xiong M
Year: 2021
Journal: Sci Transl Med
Title: APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.
Volume: 13
Issue: 581
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Publication
22441102 | J:196923
First Author: Eberlé D
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.
Volume: 32
Issue: 5
Pages: 1116-23
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Publication
21965021 | J:178125
First Author: Di Bartolo BA
Year: 2011
Journal: Diabetologia
Title: TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe ⁻/⁻ mice.
Volume: 54
Issue: 12
Pages: 3157-67
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Publication
11122341 | J:129722
First Author: Horsburgh K
Year: 2000
Journal: Eur J Neurosci
Title: Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia.
Volume: 12
Issue: 12
Pages: 4309-17
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Publication
30201630 | J:267447
First Author: Anantharamaiah GM
Year: 2018
Journal: J Lipid Res
Title: Novel fatty acyl apoE mimetic peptides have increased potency to reduce plasma cholesterol in mice and macaques.
Volume: 59
Issue: 11
Pages: 2075-2083
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Publication
35281895 | J:321886
 
First Author: Yao L
Year: 2022
Journal: Front Pharmacol
Title: Induction of Heme Oxygenase-1 Modifies the Systemic Immunity and Reduces Atherosclerotic Lesion Development in ApoE Deficient Mice.
Volume: 13
Pages: 809469
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Publication
34385572 | J:313878
First Author: Agergaard J
Year: 2021
Journal: Sci Rep
Title: Impaired skeletal muscle hypertrophy signaling and amino acid deprivation response in Apoe knockout mice with an unhealthy lipoprotein distribution.
Volume: 11
Issue: 1
Pages: 16423
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Publication
24755147 | J:283480
First Author: Sui Y
Year: 2014
Journal: J Am Heart Assoc
Title: Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice.
Volume: 3
Issue: 2
Pages: e000492
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Publication
36634180 | J:343013
First Author: Seo DO
Year: 2023
Journal: Science
Title: ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.
Volume: 379
Issue: 6628
Pages: eadd1236
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Publication
32004344 | J:284870
First Author: Rhea EM
Year: 2020
Journal: PLoS One
Title: Insulin BBB pharmacokinetics in young apoE male and female transgenic mice.
Volume: 15
Issue: 1
Pages: e0228455
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Publication
27866224 | J:238722
First Author: Han JH
Year: 2017
Journal: Diabetologia
Title: The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE -/- mice fed a western diet.
Volume: 60
Issue: 2
Pages: 364-376
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Publication
9649566 | J:48565
First Author: Sullivan PM
Year: 1998
Journal: J Clin Invest
Title: Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2.
Volume: 102
Issue: 1
Pages: 130-5
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10938015 | J:130658
First Author: Thorngate FE
Year: 2000
Journal: Arterioscler Thromb Vasc Biol
Title: Low levels of extrahepatic nonmacrophage ApoE inhibit atherosclerosis without correcting hypercholesterolemia in ApoE-deficient mice.
Volume: 20
Issue: 8
Pages: 1939-45
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Publication
38020764 | J:343135
 
First Author: Balu D
Year: 2023
Journal: Front Aging Neurosci
Title: APOE genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice.
Volume: 15
Pages: 1279343
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22159114 | J:178910
First Author: Kim J
Year: 2011
Journal: J Neurosci
Title: Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis.
Volume: 31
Issue: 49
Pages: 18007-12
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Publication
30509127 | J:288004
First Author: Christensen A
Year: 2019
Journal: FASEB J
Title: APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice.
Volume: 33
Issue: 3
Pages: 4054-4066
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Protein
Q921B5
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
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Publication
39532095 | J:360629
First Author: Guo JL
Year: 2025
Journal: Cell
Title: Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.
Volume: 188
Issue: 1
Pages: 187-206.e26
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Publication
29038051 | J:255655
First Author: Nam KN
Year: 2018
Journal: Biochim Biophys Acta
Title: Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.
Volume: 1864
Issue: 1
Pages: 152-161
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Publication
31623648 | J:311531
First Author: Huynh TV
Year: 2019
Journal: Mol Neurodegener
Title: Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model.
Volume: 14
Issue: 1
Pages: 37
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Publication
37337279 | J:348690
First Author: Williams T
Year: 2023
Journal: Acta Neuropathol Commun
Title: Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.
Volume: 11
Issue: 1
Pages: 99
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Publication
34643971 | J:325639
First Author: Henningfield CM
Year: 2022
Journal: Glia
Title: Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression.
Volume: 70
Issue: 2
Pages: 287-302
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Publication
11950276 | J:127846
First Author: Fagan AM
Year: 2002
Journal: Neurobiol Dis
Title: Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.
Volume: 9
Issue: 3
Pages: 305-18
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Publication
20877628 | J:165109
First Author: Hoving S
Year: 2010
Journal: PLoS One
Title: NO-donating aspirin and aspirin partially inhibit age-related atherosclerosis but not radiation-induced atherosclerosis in ApoE null mice.
Volume: 5
Issue: 9
Pages: e12874
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Publication
21159735 | J:169320
First Author: Becker LE
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Effect of paricalcitol and calcitriol on aortic wall remodeling in uninephrectomized ApoE knockout mice.
Volume: 300
Issue: 3
Pages: F772-82
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Publication
14738889 | J:105285
First Author: Vliegen I
Year: 2004
Journal: Microbes Infect
Title: Cytomegalovirus infection aggravates atherogenesis in apoE knockout mice by both local and systemic immune activation.
Volume: 6
Issue: 1
Pages: 17-24
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Publication
25666507 | J:223831
First Author: Sorrentino R
Year: 2015
Journal: Cell Immunol
Title: A single infection with Chlamydia pneumoniae is sufficient to exacerbate atherosclerosis in ApoE deficient mice.
Volume: 294
Issue: 1
Pages: 25-32
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Publication
11116057 | J:102940
First Author: Rosenfeld ME
Year: 2000
Journal: Arterioscler Thromb Vasc Biol
Title: Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse.
Volume: 20
Issue: 12
Pages: 2587-92
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Publication
23620513 | J:359709
First Author: Verghese PB
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions.
Volume: 110
Issue: 19
Pages: E1807-16
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Publication
17079794 | J:118226
First Author: Lucic D
Year: 2007
Journal: J Lipid Res
Title: Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor.
Volume: 48
Issue: 2
Pages: 366-72
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Publication
31917799 | J:285153
First Author: Shang Y
Year: 2020
Journal: PLoS One
Title: Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice.
Volume: 15
Issue: 1
Pages: e0225392
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Publication
31207469 | J:281528
 
First Author: Jiang C
Year: 2019
Journal: Neurobiol Aging
Title: Cyclic O3 exposure synergizes with aging leading to memory impairment in male APOE ε3, but not APOE ε4, targeted replacement mice.
Volume: 81
Pages: 9-21
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Publication
28212814 | J:241590
First Author: Postupna N
Year: 2017
Journal: Am J Pathol
Title: Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE ε4.
Volume: 187
Issue: 4
Pages: 884-895
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Publication
31861986 | J:292924
First Author: Maldonado Weng J
Year: 2019
Journal: Mol Neurodegener
Title: Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice.
Volume: 14
Issue: 1
Pages: 47
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Publication
25178844 | J:230478
First Author: Xie P
Year: 2014
Journal: Biochim Biophys Acta
Title: Transgenic CGI-58 expression in macrophages alleviates the atherosclerotic lesion development in ApoE knockout mice.
Volume: 1841
Issue: 12
Pages: 1683-90
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Publication
30776415 | J:275537
First Author: Hoekstra M
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Inhibition of PRMT3 activity reduces hepatic steatosis without altering atherosclerosis susceptibility in apoE knockout mice.
Volume: 1865
Issue: 6
Pages: 1402-1409
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Publication
26400930 | J:226389
First Author: Segev Y
Year: 2015
Journal: J Neurosci
Title: PKR Inhibition Rescues Memory Deficit and ATF4 Overexpression in ApoE ε4 Human Replacement Mice.
Volume: 35
Issue: 38
Pages: 12986-93
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Publication
27683909 | J:235715
First Author: Lane-Donovan C
Year: 2016
Journal: J Neurosci
Title: Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice.
Volume: 36
Issue: 39
Pages: 10141-50
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Publication
36206387 | J:341023
First Author: McLean JW
Year: 2022
Journal: Learn Mem
Title: Contributions of sex and genotype to exploratory behavior differences in an aged humanized APOE mouse model of late-onset Alzheimer's disease.
Volume: 29
Issue: 9
Pages: 321-331
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Publication
22848551 | J:189699
First Author: Hawkes CA
Year: 2012
Journal: PLoS One
Title: Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele.
Volume: 7
Issue: 7
Pages: e41636
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Publication
18778362 | J:142416
First Author: Smook ML
Year: 2008
Journal: Clin Exp Immunol
Title: Anti-oxLDL antibody isotype levels, as potential markers for progressive atherosclerosis in APOE and APOECD40L mice.
Volume: 154
Issue: 2
Pages: 264-9
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Publication
22956628 | J:192764
First Author: Ngalame NN
Year: 2013
Journal: Toxicol Sci
Title: Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.
Volume: 131
Issue: 1
Pages: 225-33
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Publication
21968112 | J:178453
First Author: Murphy AJ
Year: 2011
Journal: J Clin Invest
Title: ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.
Volume: 121
Issue: 10
Pages: 4138-49
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Publication
18160459 | J:133453
First Author: Lloyd DJ
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr.
Volume: 294
Issue: 3
Pages: E496-505
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Publication
15794991 | J:97643
First Author: Grootendorst J
Year: 2005
Journal: Behav Brain Res
Title: Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior.
Volume: 159
Issue: 1
Pages: 1-14
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Publication
23018124 | J:197084
 
First Author: Yeiser LA
Year: 2013
Journal: Behav Brain Res
Title: ApoE isoform modulates effects of cranial ⁵⁶Fe irradiation on spatial learning and memory in the water maze.
Volume: 237
Pages: 207-14
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Publication
34687487 | J:314722
First Author: Zhang Z
Year: 2021
Journal: Aging Cell
Title: Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?
Volume: 20
Issue: 11
Pages: e13501
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Publication
15229191 | J:92095
First Author: Mann KM
Year: 2004
Journal: Hum Mol Genet
Title: Independent effects of APOE on cholesterol metabolism and brain Abeta levels in an Alzheimer disease mouse model.
Volume: 13
Issue: 17
Pages: 1959-68
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Publication
19457069 | J:152822
First Author: Chan A
Year: 2009
Journal: J Neurochem
Title: Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: potentiation by ApoE genotype and alleviation by S-adenosyl methionine.
Volume: 110
Issue: 3
Pages: 831-6
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Publication
34099706 | J:322192
First Author: Fitz NF
Year: 2021
Journal: Nat Commun
Title: Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 3416
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Publication
31275318 | J:297230
 
First Author: Lee YS
Year: 2019
Journal: Front Immunol
Title: Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.
Volume: 10
Pages: 1379
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Publication
12951361 | J:193807
First Author: Thorngate FE
Year: 2003
Journal: J Lipid Res
Title: Testing the role of apoA-I, HDL, and cholesterol efflux in the atheroprotective action of low-level apoE expression.
Volume: 44
Issue: 12
Pages: 2331-8
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Publication
19033669 | J:144730
First Author: Deane R
Year: 2008
Journal: J Clin Invest
Title: apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Volume: 118
Issue: 12
Pages: 4002-13
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Publication
8696940 | J:111962
First Author: Roselaar SE
Year: 1996
Journal: Arterioscler Thromb Vasc Biol
Title: Lymphocyte populations in atherosclerotic lesions of apoE -/- and LDL receptor -/- mice. Decreasing density with disease progression.
Volume: 16
Issue: 8
Pages: 1013-8
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Publication
15287908 | J:107867
First Author: Yao J
Year: 2004
Journal: J Neurochem
Title: Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.
Volume: 90
Issue: 4
Pages: 1011-8
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Publication
15746445 | J:107632
First Author: Mercer J
Year: 2005
Journal: Circ Res
Title: Endogenous p53 protects vascular smooth muscle cells from apoptosis and reduces atherosclerosis in ApoE knockout mice.
Volume: 96
Issue: 6
Pages: 667-74
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Publication
38713704 | J:351101
First Author: Onos KD
Year: 2024
Journal: Alzheimers Dement
Title: Assessment of neurovascular uncoupling: APOE status is a key driver of early metabolic and vascular dysfunction.
Volume: 20
Issue: 7
Pages: 4951-4969
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Publication
20416362 | J:165367
First Author: Jenner AM
Year: 2010
Journal: Neuroscience
Title: The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice.
Volume: 169
Issue: 1
Pages: 109-15
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Publication
31294626 | J:307448
First Author: Ortega R
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Angiotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice.
Volume: 39
Issue: 8
Pages: 1614-1628
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•
•
•
•
Publication
35838553 | J:351121
First Author: Sepulveda J
Year: 2022
Journal: J Neurochem
Title: Independent APOE4 knock-in mouse models display reduced brain APOE protein, altered neuroinflammation, and simplification of dendritic spines.
Volume: 163
Issue: 3
Pages: 247-259
•
•
•
•
•
Publication
10195942 | J:55980
First Author: Plump AS
Year: 1999
Journal: Arterioscler Thromb Vasc Biol
Title: Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.
Volume: 19
Issue: 4
Pages: 1105-10
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•
•
•
•
Publication
28502803 | J:259161
 
First Author: Castranio EL
Year: 2017
Journal: Neurobiol Dis
Title: Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury.
Volume: 105
Pages: 1-14
•
•
•
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Publication
22291917 | J:224062
First Author: Ponnuswamy P
Year: 2012
Journal: PLoS One
Title: eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice.
Volume: 7
Issue: 1
Pages: e30193
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•
•
•
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Publication
29967007 | J:265702
First Author: Wu L
Year: 2018
Journal: J Neurosci
Title: Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention.
Volume: 38
Issue: 30
Pages: 6665-6681
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•
•
•
•
Publication
37620511 | J:341085
First Author: Jin S
Year: 2023
Journal: Nat Commun
Title: Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation.
Volume: 14
Issue: 1
Pages: 5150
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•
•
•
•
Publication
30082275 | J:266690
First Author: Kang SS
Year: 2018
Journal: J Exp Med
Title: Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau.
Volume: 215
Issue: 9
Pages: 2235-2245
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•
•
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•
Publication
21347323 | J:171093
First Author: To AW
Year: 2011
Journal: PLoS One
Title: The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice.
Volume: 6
Issue: 2
Pages: e16991
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•
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Publication
22883908 | J:194428
First Author: Segev Y
Year: 2013
Journal: Neurobiol Aging
Title: ApoE ε4 is associated with eIF2α phosphorylation and impaired learning in young mice.
Volume: 34
Issue: 3
Pages: 863-72
•
•
•
•
•
Publication
12576523 | J:82073
First Author: Gerritsen G
Year: 2003
Journal: J Lipid Res
Title: Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain.
Volume: 44
Issue: 2
Pages: 408-14
•
•
•
•
•
Publication
25421060 | J:219838
First Author: Huang ZH
Year: 2015
Journal: J Lipid Res
Title: Selective suppression of adipose tissue apoE expression impacts systemic metabolic phenotype and adipose tissue inflammation.
Volume: 56
Issue: 2
Pages: 215-26
•
•
•
•
•
Publication
34795427 | J:317743
First Author: Yu TS
Year: 2021
Journal: Commun Biol
Title: Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice.
Volume: 4
Issue: 1
Pages: 1303
•
•
•
•
•
Publication
11120597 | J:66874
First Author: Harry GJ
Year: 2000
Journal: Brain Behav Immun
Title: Age-dependent cytokine responses: trimethyltin hippocampal injury in wild-type, APOE knockout, and APOE4 mice.
Volume: 14
Issue: 4
Pages: 288-304
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•
•
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Publication
17101197 | J:130695
First Author: Miller RM
Year: 2008
Journal: Neurobiol Aging
Title: Isoform-specific effects of ApoE on HSV immediate early gene expression and establishment of latency.
Volume: 29
Issue: 1
Pages: 71-7
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•
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Publication
26073697 | J:225432
 
First Author: Jiang L
Year: 2015
Journal: Neuroscience
Title: Effects of ApoE on intracellular calcium levels and apoptosis of neurons after mechanical injury.
Volume: 301
Pages: 375-83
•
•
•
•
•
Publication
30284204 | J:295609
First Author: Speidell AP
Year: 2019
Journal: Neurotox Res
Title: Development of a Human APOE Knock-in Mouse Model for Study of Cognitive Function After Cancer Chemotherapy.
Volume: 35
Issue: 2
Pages: 291-303
•
•
•
•
•
Publication
38054039 | J:343302
 
First Author: Brojakowska A
Year: 2023
Journal: Front Physiol
Title: Lifetime evaluation of left ventricular structure and function in male ApoE null mice after gamma and space-type radiation exposure.
Volume: 14
Pages: 1292033
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