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Search results 101 to 200 out of 1150 for Arx

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450750
Age: embryonic day 12.5
Image: Arx - E12.5
Note: There is strong staining in the mantle zone of the dorsal and ventral POAs. Staining is either absent or ubiquitous in the mantle zone of the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Arx - E12.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: Staining is very strong in the MZ of the dorsal POA, strong in the ventral POA & ARH nucleus, strong & scattered in the AVH & the DAH & moderate & scattered in the PH. Staining is either absent or ubiquitous in the MZ of the PVH, SCH, DMH & VMH nuclei.
Specimen Label: Arx - E16.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: There is strong staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones.
Specimen Label: Arx - E16.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450750
Age: embryonic day 12.5
Image: Arx - E12.5
Note: There is strong staining in the ventricular zone of the anterior and posterior IDs. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and the AVH.
Specimen Label: Arx - E12.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450750
Age: embryonic day 14.5
Image: Arx - E14.5
Note: There is strong, scattered staining in the ventricular zone of the posterior ID. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior ID.
Specimen Label: Arx - E14.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: There is moderate, scattered staining in the ventricular zone of the DMH nucleus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Arx - E16.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3724556
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826236
Age: embryonic day 14.5
Image: Additional file 4 Arx
Specimen Label: Additional file 4 Arx
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450750
Age: embryonic day 12.5
Image: Arx - E12.5
Note: There is moderate staining in the ventricular zone of the cerebral cortex.
Specimen Label: Arx - E12.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: There is very strong, scattered staining in the ventricular zone of the cerebral cortex.
Specimen Label: Arx - E16.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Arx - E16.5
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Arx - E16.5
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450750
Age: embryonic day 11.5
Image: Arx - E11.5
Note: Staining is strong in the MZ of anterior & posterior IDs & TT, moderate in the dorsal POA, weak & scattered in the dorsal thalamus & either absent or ubiquitous in the prethalamus, ventral POA, PVH, VMH & ARH nuclei, AVH & premam, mam & supramam zones.
Specimen Label: Arx - E11.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442703
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450750
Age: embryonic day 16.5
Image: Arx - E16.5
Note: There is very strong staining in the mantle zone of the prethalamus. Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus.
Specimen Label: Arx - E16.5
Detected: true
Specimen Num: 7
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Publication
9256348 | J:42033
First Author: Miura H
Year: 1997
Journal: Mech Dev
Title: Expression of a novel aristaless related homeobox gene 'Arx' in the vertebrate telencephalon, diencephalon and floor plate.
Volume: 65
Issue: 1-2
Pages: 99-109
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Publication
24968361 | J:214968
First Author: Cho G
Year: 2014
Journal: Dev Biol
Title: Arx together with FoxA2, regulates Shh floor plate expression.
Volume: 393
Issue: 1
Pages: 137-48
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Publication
35656878 | J:335087
First Author: Lim Y
Year: 2022
Journal: Genesis
Title: Generation of FLAG-tagged Arx knock-in mouse model.
Volume: 60
Issue: 6-7
Pages: e23479
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Publication
30659230 | J:275488
First Author: Lim Y
Year: 2019
Journal: Sci Rep
Title: Arx Expression Suppresses Ventralization of the Developing Dorsal Forebrain.
Volume: 9
Issue: 1
Pages: 226
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Publication
18799476 | J:138839
First Author: Fulp CT
Year: 2008
Journal: Hum Mol Genet
Title: Identification of Arx transcriptional targets in the developing basal forebrain.
Volume: 17
Issue: 23
Pages: 3740-60
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Publication
23785486 | J:203476
First Author: Wilcox CL
Year: 2013
Journal: PLoS One
Title: Pancreatic α-cell specific deletion of mouse Arx leads to α-cell identity loss.
Volume: 8
Issue: 6
Pages: e66214
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Publication
22565167 | J:197588
First Author: Olivetti PR
Year: 2012
Journal: Curr Opin Neurobiol
Title: Interneuron, interrupted: molecular pathogenesis of ARX mutations and X-linked infantile spasms.
Volume: 22
Issue: 5
Pages: 859-65
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Publication
22108177 | J:180595
First Author: Nasrallah MP
Year: 2012
Journal: Hum Mol Genet
Title: Differential effects of a polyalanine tract expansion in Arx on neural development and gene expression.
Volume: 21
Issue: 5
Pages: 1090-8
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Publication
12536326 | J:82137
First Author: El-Hodiri HM
Year: 2003
Journal: Dev Genes Evol
Title: The Xenopus arx gene is expressed in the developing rostral forebrain.
Volume: 212
Issue: 12
Pages: 608-12
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Publication
31923647 | J:306907
First Author: Kodani N
Year: 2020
Journal: iScience
Title: FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression.
Volume: 23
Issue: 1
Pages: 100798
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Publication
24487799 | J:306019
First Author: Sunnen CN
Year: 2014
Journal: J Neuropathol Exp Neurol
Title: Arx is required for specification of the zona incerta and reticular nucleus of the thalamus.
Volume: 73
Issue: 3
Pages: 253-61
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Publication
24204325 | J:205133
First Author: Courtney M
Year: 2013
Journal: PLoS Genet
Title: The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Volume: 9
Issue: 10
Pages: e1003934
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Publication
21388963 | J:172083
First Author: Liu J
Year: 2011
Journal: J Biol Chem
Title: Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development.
Volume: 286
Issue: 17
Pages: 15352-60
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Publication
14561778 | J:86206
First Author: Collombat P
Year: 2003
Journal: Genes Dev
Title: Opposing actions of Arx and Pax4 in endocrine pancreas development.
Volume: 17
Issue: 20
Pages: 2591-603
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Publication
19439424 | J:148311
First Author: Marsh E
Year: 2009
Journal: Brain
Title: Targeted loss of Arx results in a developmental epilepsy mouse model and recapitulates the human phenotype in heterozygous females.
Volume: 132
Issue: Pt 6
Pages: 1563-76
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Publication
22387004 | J:184887
First Author: Du A
Year: 2012
Journal: Dev Biol
Title: Arx is required for normal enteroendocrine cell development in mice and humans.
Volume: 365
Issue: 1
Pages: 175-88
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Publication
23968833 | J:229227
First Author: Colasante G
Year: 2015
Journal: Cereb Cortex
Title: ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c.
Volume: 25
Issue: 2
Pages: 322-35
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Publication
21856296 | J:178173
First Author: Mastracci TL
Year: 2011
Journal: Dev Biol
Title: Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression.
Volume: 359
Issue: 1
Pages: 1-11
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Publication
18509041 | J:136386
First Author: Friocourt G
Year: 2008
Journal: J Neurosci
Title: Cell-autonomous roles of ARX in cell proliferation and neuronal migration during corticogenesis.
Volume: 28
Issue: 22
Pages: 5794-805
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Publication
24452264 | J:213527
First Author: Olivetti PR
Year: 2014
Journal: Sci Transl Med
Title: Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome.
Volume: 6
Issue: 220
Pages: 220ra12
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Publication
15677725 | J:96969
First Author: Yoshihara S
Year: 2005
Journal: Development
Title: Arx homeobox gene is essential for development of mouse olfactory system.
Volume: 132
Issue: 4
Pages: 751-62
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Publication
35094084 | J:334646
First Author: Drongitis D
Year: 2022
Journal: Hum Mol Genet
Title: Deregulation of microtubule organization and RNA metabolism in Arx models for lissencephaly and developmental epileptic encephalopathy.
Volume: 31
Issue: 11
Pages: 1884-1908
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Publication
17404619 | J:121231
First Author: Collombat P
Year: 2007
Journal: J Clin Invest
Title: Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.
Volume: 117
Issue: 4
Pages: 961-70
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Publication
22570716 | J:187259
First Author: Beucher A
Year: 2012
Journal: PLoS One
Title: The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice.
Volume: 7
Issue: 5
Pages: e36449
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Publication
17932502 | J:141473
First Author: Biressi S
Year: 2008
Journal: Cell Death Differ
Title: The homeobox gene Arx is a novel positive regulator of embryonic myogenesis.
Volume: 15
Issue: 1
Pages: 94-104
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Publication
24122442 | J:206228
First Author: Lee K
Year: 2014
Journal: Hum Mol Genet
Title: Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation.
Volume: 23
Issue: 4
Pages: 1084-94
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Publication
14992814 | J:88461
First Author: Poirier K
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons.
Volume: 122
Issue: 1
Pages: 35-46
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Publication
19605412 | J:152416
First Author: Kitamura K
Year: 2009
Journal: Hum Mol Genet
Title: Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice.
Volume: 18
Issue: 19
Pages: 3708-24
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Publication
24236044 | J:209317
First Author: Wilcox CL
Year: 2013
Journal: PLoS One
Title: Arx polyalanine expansion in mice leads to reduced pancreatic α-cell specification and increased α-cell death.
Volume: 8
Issue: 11
Pages: e78741
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Publication
29659809 | J:262482
First Author: Dubos A
Year: 2018
Journal: Hum Mol Genet
Title: A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.
Volume: 27
Issue: 12
Pages: 2138-2153
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Publication
27798109 | J:241394
First Author: Mattiske T
Year: 2016
Journal: Hum Mol Genet
Title: Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.
Volume: 25
Issue: 24
Pages: 5433-5443
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Publication
28602636 | J:260340
 
First Author: Jackson MR
Year: 2017
Journal: Neurobiol Dis
Title: Extensive phenotyping of two ARX polyalanine expansion mutation mouse models that span clinical spectrum of intellectual disability and epilepsy.
Volume: 105
Pages: 245-256
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Publication
12379852 | J:79871
First Author: Kitamura K
Year: 2002
Journal: Nat Genet
Title: Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans.
Volume: 32
Issue: 3
Pages: 359-69
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Publication
18923043 | J:141087
First Author: Colasante G
Year: 2008
Journal: J Neurosci
Title: Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons.
Volume: 28
Issue: 42
Pages: 10674-86
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Publication
19627984 | J:153556
First Author: Colasante G
Year: 2009
Journal: Dev Biol
Title: Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity.
Volume: 334
Issue: 1
Pages: 59-71
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Publication
21880149 | J:176201
 
First Author: Kordowich S
Year: 2011
Journal: BMC Dev Biol
Title: Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage.
Volume: 11
Pages: 52
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Publication
22628459 | J:210152
First Author: Beguin S
Year: 2013
Journal: Cereb Cortex
Title: An epilepsy-related ARX polyalanine expansion modifies glutamatergic neurons excitability and morphology without affecting GABAergic neurons development.
Volume: 23
Issue: 6
Pages: 1484-94
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Publication
28627419 | J:243952
 
First Author: Lee K
Year: 2017
Journal: Neuroscience
Title: ARX polyalanine expansion mutations lead to migration impediment in the rostral cortex coupled with a developmental deficit of calbindin-positive cortical GABAergic interneurons.
Volume: 357
Pages: 220-231
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Publication
15930104 | J:98803
First Author: Collombat P
Year: 2005
Journal: Development
Title: The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.
Volume: 132
Issue: 13
Pages: 2969-80
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Publication
9347917 | J:43579
First Author: Kitamura K
Year: 1997
Journal: Mech Dev
Title: Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation.
Volume: 67
Issue: 1
Pages: 83-96
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Publication
33490907 | J:314770
First Author: Joseph DJ
Year: 2021
Journal: iScience
Title: Postnatal Arx transcriptional activity regulates functional properties of PV interneurons.
Volume: 24
Issue: 1
Pages: 101999
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189811
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Arx
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189811
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Arx
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189811
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Arx
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189811
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Arx
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189811
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Arx
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189811
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Arx
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6167811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189811
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Arx
Detected: true
Specimen Num: 7
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Publication
29358049 | J:254531
First Author: Dickel DE
Year: 2018
Journal: Cell
Title: Ultraconserved Enhancers Are Required for Normal Development.
Volume: 172
Issue: 3
Pages: 491-499.e15
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GXD Expression
GXD Expression
 
Probe: MGI:6468293
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468309
Age: embryonic day 10.5
Image: 5A Alcam Arx +/y
Specimen Label: 5A Alcam Arx +/y
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6468293
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468309
Age: embryonic day 10.5
Image: 5A Alcam Arx -/y
Note: Reduced expression in floor plate of spinal cord.
Specimen Label: 5A Alcam Arx -/y
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6468294
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468310
Age: embryonic day 10.5
Image: 5A Shh Arx +/y
Specimen Label: 5A Shh Arx +/y
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:6468294
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468310
Age: embryonic day 10.5
Image: 5A Shh Arx -/y
Note: Reduced intensity and overall area of expression.
Specimen Label: 5A Shh Arx -/y
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468295
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6468312
Age: embryonic day 12.5
Image: S1 Arx +/y (upper)
Specimen Label: S1 Arx +/y (upper)
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6468295
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6468312
Age: embryonic day 12.5
Image: S1 Arx -/y (upper)
Note: Expression levels and number of expresing cells are slightly reduced in mutant compared to wild type.
Specimen Label: S1 Arx -/y (upper)
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468295
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6468312
Age: embryonic day 12.5
Image: S1 Arx +/y (lower)
Specimen Label: S1 Arx +/y (lower)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468295
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6468312
Age: embryonic day 12.5
Image: S1 Arx -/y (lower)
Specimen Label: S1 Arx -/y (lower)
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468297
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6468314
Age: embryonic day 11.5
Image: 5B E11.5 Arx +/y
Specimen Label: 5B E11.5 Arx +/y
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6468297
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6468314
Age: embryonic day 11.5
Image: 5B E11.5 Arx -/y
Note: Reduced number of expressing cells.
Specimen Label: 5B E11.5 Arx -/y
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468293
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468309
Age: embryonic day 10.5
Image: 5A Alcam Arx +/y
Specimen Label: 5A Alcam Arx +/y
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468293
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468309
Age: embryonic day 10.5
Image: 5A Alcam Arx -/y
Specimen Label: 5A Alcam Arx -/y
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468294
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468310
Age: embryonic day 10.5
Image: 5A Shh Arx +/y
Specimen Label: 5A Shh Arx +/y
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468294
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619117
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6468310
Age: embryonic day 10.5
Image: 5A Shh Arx -/y
Specimen Label: 5A Shh Arx -/y
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6468297
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6468314
Age: embryonic day 14.5
Image: 5B E14.5 Arx +/y
Specimen Label: 5B E14.5 Arx +/y
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6468297
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6468314
Age: embryonic day 14.5
Image: 5B E14.5 Arx -/y
Note: Reduced number of expressing cells.
Specimen Label: 5B E14.5 Arx -/y
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
32033960 | J:289976
 
First Author: Siehr MS
Year: 2020
Journal: Dis Model Mech
Title: Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome.
Volume: 13
Issue: 3
•
•
•
•
•
Publication
19553693 | J:151395
First Author: Marsh ED
Year: 2009
Journal: Dis Model Mech
Title: Developing an animal model for infantile spasms: pathogenesis, problems and progress.
Volume: 2
Issue: 7-8
Pages: 329-35
•
•
•
•
•
Publication
29953253 | J:273403
First Author: Terry NA
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Lipid malabsorption from altered hormonal signaling changes early gut microbial responses.
Volume: 315
Issue: 4
Pages: G580-G591
•
•
•
•
•
Publication
25259520 | J:224575
First Author: Bourgeois EB
Year: 2014
Journal: PLoS One
Title: A toolbox for spatiotemporal analysis of voltage-sensitive dye imaging data in brain slices.
Volume: 9
Issue: 9
Pages: e108686
•
•
•
•
•
Publication
11956759 | J:76080
First Author: Cunningham D
Year: 2002
Journal: Mamm Genome
Title: exma: an X-linked insertional mutation that disrupts forebrain and eye development.
Volume: 13
Issue: 4
Pages: 179-85
•
•
•
•
•
Publication
32608477 | J:309608
 
First Author: Shi X
Year: 2020
Journal: Biosci Rep
Title: Identification and validation of the phosphorylation sites on Aristaless-related homeobox protein.
Volume: 40
Issue: 7
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1
Description: Homeobox protein ARX
Type: chain
End: 564
•
•
•
•
•
Publication
28215845 | J:251955
First Author: Chakravarthy H
Year: 2017
Journal: Cell Metab
Title: Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
Volume: 25
Issue: 3
Pages: 622-634
•
•
•
•
•
Publication
20592160 | J:182855
First Author: Hancock AS
Year: 2010
Journal: Mol Endocrinol
Title: Glucagon deficiency reduces hepatic glucose production and improves glucose tolerance in adult mice.
Volume: 24
Issue: 8
Pages: 1605-14
•
•
•
•
•
Publication
17803355 | J:128347
First Author: Ahituv N
Year: 2007
Journal: PLoS Biol
Title: Deletion of ultraconserved elements yields viable mice.
Volume: 5
Issue: 9
Pages: e234
•
•
•
•
•
Publication
27287386 | J:316111
First Author: Marsh ED
Year: 2016
Journal: BMC Neurosci
Title: Developmental interneuron subtype deficits after targeted loss of Arx.
Volume: 17
Issue: 1
Pages: 35
•
•
•
•
•
Publication
22056672 | J:177838
First Author: Papizan JB
Year: 2011
Journal: Genes Dev
Title: Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.
Volume: 25
Issue: 21
Pages: 2291-305
•
•
•
•
•
Publication
11971879 | J:76798
First Author: Bienvenu T
Year: 2002
Journal: Hum Mol Genet
Title: ARX, a novel Prd-class-homeobox gene highly expressed in the telencephalon, is mutated in X-linked mental retardation.
Volume: 11
Issue: 8
Pages: 981-91
•
•
•
•
•
Publication
36167470 | J:333068
First Author: Burgess RJ
Year: 2022
Journal: Genes Dev
Title: Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells.
Volume: 36
Issue: 15-16
Pages: 887-900
•
•
•
•
•
Publication
21497756 | J:171614
First Author: Dhawan S
Year: 2011
Journal: Dev Cell
Title: Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.
Volume: 20
Issue: 4
Pages: 419-29
•
•
•
•
•
Publication
19587282 | J:151082
First Author: Price MG
Year: 2009
Journal: J Neurosci
Title: A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment.
Volume: 29
Issue: 27
Pages: 8752-63
•
•
•
•
•
Publication
11889467 | J:75810
First Author: Strømme P
Year: 2002
Journal: Nat Genet
Title: Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy.
Volume: 30
Issue: 4
Pages: 441-5
•
•
•
•
•
Publication
17331656 | J:122008
First Author: McKenzie O
Year: 2007
Journal: Neuroscience
Title: Aristaless-related homeobox gene, the gene responsible for West syndrome and related disorders, is a Groucho/transducin-like enhancer of split dependent transcriptional repressor.
Volume: 146
Issue: 1
Pages: 236-47
•
•
•
•
•
Author
Von Arx A
•
•
•
•
•
Author
Von Arx F
•
•
•
•
•
Publication
23246292 | J:203650
First Author: Poeta L
Year: 2013
Journal: Am J Hum Genet
Title: A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARX.
Volume: 92
Issue: 1
Pages: 114-25
•
•
•
•
•
Publication
19494118 | J:152732
First Author: Lin W
Year: 2009
Journal: J Biol Chem
Title: The roles of multiple importins for nuclear import of murine aristaless-related homeobox protein.
Volume: 284
Issue: 30
Pages: 20428-39
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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