|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 154 out of 154 for Astn1

<< First    < Previous  |  Next >    Last >>
0.019s

Categories

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4462464
Assay Type: RNA in situ
Annotation Date: 2010-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4462477
Age: postnatal day 6
Image: 2K
Specimen Label: 2K
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
10444330 | J:54765
First Author: Bergstrom DE
Year: 1999
Journal: Genomics
Title: Genetic and physical mapping of the dreher locus on mouse chromosome 1.
Volume: 59
Issue: 3
Pages: 291-9
•
•
•
•
•
Publication
15520881 | J:93967
First Author: Cheung CC
Year: 2004
Journal: Mamm Genome
Title: Quantitative trait loci for steady-state platelet count in mice.
Volume: 15
Issue: 10
Pages: 784-97
•
•
•
•
•
Publication
27452274 | J:258293
 
First Author: Divya TS
Year: 2016
Journal: Sci Rep
Title: Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development.
Volume: 6
Pages: 30337
•
•
•
•
•
Publication
20151419 | J:162273
First Author: Faux C
Year: 2010
Journal: J Comp Neurol
Title: Differential gene expression in migrating cortical interneurons during mouse forebrain development.
Volume: 518
Issue: 8
Pages: 1232-48
•
•
•
•
•
Publication
30250269 | J:279065
First Author: Liu W
Year: 2018
Journal: Cell Death Dis
Title: MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development.
Volume: 9
Issue: 10
Pages: 999
•
•
•
•
•
Publication
21800304 | J:187345
First Author: Piper M
Year: 2011
Journal: J Comp Neurol
Title: Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum.
Volume: 519
Issue: 17
Pages: 3532-48
•
•
•
•
•
Publication
12465718 | J:86755
First Author: Okazaki N
Year: 2002
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 9
Issue: 5
Pages: 179-88
•
•
•
•
•
Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
•
•
•
•
•
Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Protein Domain
IPR026995 | Astrotactin
Type: Family
Description: Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
•
•
•
•
•
Protein Domain
IPR045575 | ASTN_1_2_N
Type: Domain
Description: This entry represents the N-terminal domain of ASTN1/2. This domain includes the transmembrane and cytosolic regions [].Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
•
•
•
•
•
Protein
A0A0A6YWD1
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
•
•
•
•
•
Protein
A0A0A6YWJ9
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
•
•
•
•
•
Protein Domain
IPR045574 | ASTN1_2_EGF_Fn
Type: Domain
Description: This domain localises to the middle of the C-terminal region of ASTN1 and 2, which comprises a EGF- like domain (EGF4) and a fibronectin type III (Fn(III)) domain []. These subdomains are located between the MACPF and annexin-like domains. The structure of Fn(III) from ASTN2 revealed an unexpected feature which has two additional beta strands folded across the core. The junction between EGF-4 and Fn(III) domains in ASTN2 (but not in ASTN1) is thought to be an inositol triphosphate binding site [].Astrotactin-1 and 2 (ASTN1/2) are integral membrane perforin-like, vertebrate-specific proteins that play critical roles in neurodevelopment [, ]. They consist of an N-terminal cytosolic domain suspended between two transmembrane α-helices with a large C-terminal domain, extracellular for ASTN1 and endosome luminal for ASTN2. ASTN1 acts as a neuronal receptor for granule neuron migration along astroglial fibres []. ASTN2 forms a complex with ASTN1, which regulates the surface expression of ASTN1. It mediates ASTN1 recycling by promoting its internalisation and transport during endocytosis []. ASTN2 is also involved in the planar cell polarity pathway in hair cells [].
•
•
•
•
•
Publication
27249642 | -
 
First Author: Ni T
Year: 2016
Journal: Open Biol
Title: Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Volume: 6
Issue: 5
•
•
•
•
•
Protein
A0A0A6YXJ4
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
•
•
•
•
•
Protein
Q3TPU9
Organism: Mus musculus/domesticus
Length: 840  
Fragment?: false
•
•
•
•
•
Publication
30242134 | J:266179
First Author: Behesti H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.
Volume: 115
Issue: 41
Pages: E9717-E9726
•
•
•
•
•
Publication
30262652 | J:354099
First Author: Horn Z
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: N-cadherin provides a cis and trans ligand for astrotactin that functions in glial-guided neuronal migration.
Volume: 115
Issue: 42
Pages: 10556-10563
•
•
•
•
•
Protein
A0A0A6YVT7
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
•
•
•
•
•
Protein
Q61137
Organism: Mus musculus/domesticus
Length: 1302  
Fragment?: false
•
•
•
•
•
Protein
Q80Z10
Organism: Mus musculus/domesticus
Length: 1352  
Fragment?: false
•
•
•
•
•
Protein
Q9QY74
Organism: Mus musculus/domesticus
Length: 891  
Fragment?: false
•
•
•
•
•
Protein
Q3UHD7
Organism: Mus musculus/domesticus
Length: 1294  
Fragment?: false
•
•
•
•
•
Protein
A0A0A6YWE6
Organism: Mus musculus/domesticus
Length: 1172  
Fragment?: false
•
•
•
•
•
Protein
Q8BRX1
Organism: Mus musculus/domesticus
Length: 891  
Fragment?: false
•
•
•
•
•
Publication
27042284 | J:231288
 
First Author: Berkowicz SR
Year: 2016
Journal: Mol Autism
Title: Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
Volume: 7
Pages: 22
•
•
•
•
•
Publication
31169361 | J:292826
First Author: Hirose H
Year: 2019
Journal: Chembiochem
Title: A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display.
Volume: 20
Issue: 16
Pages: 2089-2100
•
•
•
•
•
Publication
28100779 | J:241080
First Author: Chang H
Year: 2017
Journal: J Biol Chem
Title: Intramembrane Proteolysis of Astrotactins.
Volume: 292
Issue: 8
Pages: 3506-3516
•
•
•
•
•
Publication
35729251 | J:326584
First Author: Delpero M
Year: 2022
Journal: Sci Rep
Title: QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease.
Volume: 12
Issue: 1
Pages: 10471
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom