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Search results 101 to 200 out of 900 for Atg12

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_06
Specimen Label: euxassay_005505_06
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_07
Specimen Label: euxassay_005505_07
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_08
Specimen Label: euxassay_005505_08
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_09
Specimen Label: euxassay_005505_09
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_16
Specimen Label: euxassay_005505_16
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_17
Specimen Label: euxassay_005505_17
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_18
Specimen Label: euxassay_005505_18
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_19
Specimen Label: euxassay_005505_19
Detected: true
Specimen Num: 15
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_20
Specimen Label: euxassay_005505_20
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_21
Specimen Label: euxassay_005505_21
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945778
Age: postnatal day 7
Image: g01512 P7
Specimen Label: g01512 P7
Detected: true
Specimen Num: 3
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945778
Age: postnatal day 42
Image: g01512 Adult
Specimen Label: g01512 Adult
Detected: true
Specimen Num: 4
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945778
Age: embryonic day 15.5
Image: g01512 E15.5
Specimen Label: g01512 E15.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945778
Age: postnatal day 7
Image: g01512 P7
Specimen Label: g01512 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945778
Age: postnatal day 42
Image: g01512 Adult
Specimen Label: g01512 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945778
Age: embryonic day 15.5
Image: g01512 E15.5
Specimen Label: g01512 E15.5
Detected: true
Specimen Num: 2
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_07
Specimen Label: euxassay_005505_07
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_16
Specimen Label: euxassay_005505_16
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_17
Specimen Label: euxassay_005505_17
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945778
Age: embryonic day 15.5
Image: g01512 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01512 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945778
Age: postnatal day 7
Image: g01512 P7
Specimen Label: g01512 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885594
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945778
Age: postnatal day 42
Image: g01512 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01512 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_08
Specimen Label: euxassay_005505_08
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3278285
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823294
Age: embryonic day 14.5
Image: euxassay_005505_16
Specimen Label: euxassay_005505_16
Detected: true
Specimen Num: 12
•
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GO Term
GO:0061651 | Atg12 conjugating enzyme activity
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GO Term
GO:0061660 | Atg12 ligase activity
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Publication
34168038 | J:316882
First Author: Rudnick JA
Year: 2021
Journal: Genes Dev
Title: Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis.
Volume: 35
Issue: 13-14
Pages: 963-975
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•
•
Publication
32084360 | J:297254
First Author: Marsh T
Year: 2020
Journal: Dev Cell
Title: Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.
Volume: 52
Issue: 5
Pages: 591-604.e6
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Publication
25484072 | J:319961
First Author: Kim JH
Year: 2015
Journal: Autophagy
Title: Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners.
Volume: 11
Issue: 1
Pages: 75-87
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Publication
11890701 | J:75687
First Author: Tanida I
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs.
Volume: 292
Issue: 1
Pages: 256-62
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Publication
35537042 | J:329190
First Author: Yang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival.
Volume: 119
Issue: 21
Pages: e2202016119
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Publication
22520467 | J:236442
First Author: Hwang S
Year: 2012
Journal: Cell Host Microbe
Title: Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma.
Volume: 11
Issue: 4
Pages: 397-409
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Publication
23052835 | J:190998
First Author: Yang JW
Year: 2013
Journal: Histochem Cell Biol
Title: Autophagy appears during the development of the mouse lower first molar.
Volume: 139
Issue: 1
Pages: 109-18
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Publication
26098576 | J:261225
First Author: Martinez J
Year: 2015
Journal: Nat Cell Biol
Title: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.
Volume: 17
Issue: 7
Pages: 893-906
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Publication
18448665 | J:190086
First Author: Itoh T
Year: 2008
Journal: Mol Biol Cell
Title: Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation.
Volume: 19
Issue: 7
Pages: 2916-25
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Publication
18946037 | J:248272
First Author: Bell BD
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.
Volume: 105
Issue: 43
Pages: 16677-82
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Publication
24954904 | J:215480
First Author: Dooley HC
Year: 2014
Journal: Mol Cell
Title: WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.
Volume: 55
Issue: 2
Pages: 238-52
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Publication
20080761 | J:156519
First Author: Mortensen M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo.
Volume: 107
Issue: 2
Pages: 832-7
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Publication
38754428 | J:349169
     
First Author: Dellorusso PV
Year: 2024
Journal: Cell Stem Cell
Title: Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells.
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Publication
23431188 | J:196073
First Author: Tasaki T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy.
Volume: 110
Issue: 10
Pages: 3800-5
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Publication
32313051 | J:287101
First Author: Park S
Year: 2020
Journal: Nat Commun
Title: The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates.
Volume: 11
Issue: 1
Pages: 1914
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Publication
26905199 | J:301660
First Author: Li M
Year: 2016
Journal: Stem Cell Reports
Title: EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy.
Volume: 6
Issue: 3
Pages: 396-410
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Publication
27021405 | J:233601
First Author: Akinduro O
Year: 2016
Journal: J Invest Dermatol
Title: Constitutive Autophagy and Nucleophagy during Epidermal Differentiation.
Volume: 136
Issue: 7
Pages: 1460-1470
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Publication
21551061 | J:172364
First Author: Kim BH
Year: 2011
Journal: Science
Title: A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.
Volume: 332
Issue: 6030
Pages: 717-21
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Publication
23907538 | J:203690
First Author: Martinez-Lopez N
Year: 2013
Journal: EMBO Rep
Title: Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development.
Volume: 14
Issue: 9
Pages: 795-803
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Publication
38218976 | J:344311
First Author: Yan W
Year: 2024
Journal: Commun Biol
Title: Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy.
Volume: 7
Issue: 1
Pages: 94
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Publication
33436499 | J:308926
 
First Author: Yang J
Year: 2021
Journal: Sci Signal
Title: Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.
Volume: 14
Issue: 665
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Publication
22904094 | J:212629
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
25131634 | J:238190
First Author: Alldred MJ
Year: 2015
Journal: J Comp Neurol
Title: Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
Volume: 523
Issue: 1
Pages: 61-74
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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UniProt Feature
UniProt Feature
Begin: 1
Description: Ubiquitin-like protein ATG12
Type: chain
End: 141
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Gene
743425 | LOC743425
Type: gene
Organism: chimpanzee
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GO Term
GO:0019778 | Atg12 activating enzyme activity
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Publication
19417210 | J:150289
First Author: Zhang J
Year: 2009
Journal: Blood
Title: Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation.
Volume: 114
Issue: 1
Pages: 157-64
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Interaction Experiment
Radoshevich L (2010)
Description: ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.
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Publication
18768753 | J:215884
First Author: Sou YS
Year: 2008
Journal: Mol Biol Cell
Title: The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.
Volume: 19
Issue: 11
Pages: 4762-75
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Publication
12890687 | J:85938
First Author: Nemoto T
Year: 2003
Journal: J Biol Chem
Title: The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.
Volume: 278
Issue: 41
Pages: 39517-26
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Protein Coding Gene
MGI:1914045 | Atg10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915091 | Atg3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10508157 | -
First Author: Shintani T
Year: 1999
Journal: EMBO J
Title: Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.
Volume: 18
Issue: 19
Pages: 5234-41
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Protein Domain
IPR016524 | Atg10
Type: Family
Description: Atg10 is an E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. It catalyses the conjugation of Atg12 to Atg5, which is required for proper localisation of Atg8 to the preautophagosomal structure (PAS) [].
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Protein Coding Gene
MGI:1921494 | Atg7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8R1P4
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q9CPX6
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
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Protein
A0A0R4J029
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
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Publication
18398292 | -
First Author: Noda T
Year: 2008
Journal: Autophagy
Title: The Ubi brothers reunited.
Volume: 4
Issue: 4
Pages: 540-1
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Publication
17227760 | -
First Author: Yamada Y
Year: 2007
Journal: J Biol Chem
Title: The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation.
Volume: 282
Issue: 11
Pages: 8036-43
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Publication
23255127 | -
First Author: Flanagan MD
Year: 2013
Journal: Cell Cycle
Title: An Atg10-like E2 enzyme is essential for cell cycle progression but not autophagy in Schizosaccharomyces pombe.
Volume: 12
Issue: 2
Pages: 271-7
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Protein Domain
IPR007135 | Atg3/Atg10
Type: Family
Description: This entry represents a group of ubiquitin-like-conjugating enzymes, including Atg3 and Atg10.Atg3 is the E2 enzyme for the LC3 lipidation process []. It is essential for autophagocytosis. The super protein complex, the Atg16L complex, consists of multiple Atg12-Atg5 conjugates. Atg16L has an E3-like role in the LC3 lipidation reaction. The activated intermediate, LC3-Atg3 (E2), is recruited to the site where the lipidation takes place []. Atg3 catalyses the conjugation of Atg8 and phosphatidylethanolamine (PE). Atg3 has an alpha/β-fold, and its core region is topologically similar to canonical E2 enzymes. Atg3 has two regions inserted in the core region and another with a long α-helical structure that protrudes from the core region as far as 30 A []. It interacts with atg8 through an intermediate thioester bond between Cys-288 and the C-terminal Gly of atg8. It also interacts with the C-terminal region of the E1-like atg7 enzyme.Atg10 acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5 [].
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Publication
33033362 | J:301439
First Author: Yang L
Year: 2020
Journal: Commun Biol
Title: Macrophage scavenger receptor 1 controls Chikungunya virus infection through autophagy in mice.
Volume: 3
Issue: 1
Pages: 556
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