| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 42 |
| Image: |
g01516 Adult |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g01516 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689619 |
| Pattern: |
Widespread |
| Stage: |
TS19 |
| Assay Id: |
MGI:4945781 |
| Age: |
embryonic day 11.5 |
| Image: |
g01516 E11.5 |
|
| Specimen Label: |
g01516 E11.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267328 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 7 |
| Image: |
g01516 P7 |
|
| Specimen Label: |
g01516 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267328 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 42 |
| Image: |
g01516 Adult |
|
| Specimen Label: |
g01516 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133496 |
|
| Specimen Label: |
MRC Harwell_2133496 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274128 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 7 |
| Image: |
g01516 P7 |
|
| Specimen Label: |
g01516 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274128 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 42 |
| Image: |
g01516 Adult |
|
| Specimen Label: |
g01516 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1609219 |
| Pattern: |
Widespread |
| Stage: |
TS19 |
| Assay Id: |
MGI:4945781 |
| Age: |
embryonic day 11.5 |
| Image: |
g01516 E11.5 |
|
| Specimen Label: |
g01516 E11.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1683328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133499 |
|
| Specimen Label: |
MRC Harwell_2133499 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754028 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 7 |
| Image: |
g01516 P7 |
|
| Specimen Label: |
g01516 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754028 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 42 |
| Image: |
g01516 Adult |
|
| Specimen Label: |
g01516 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280923 |
| Pattern: |
Widespread |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945781 |
| Age: |
embryonic day 15.5 |
| Image: |
g01516 E15.5 |
|
| Specimen Label: |
g01516 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 7 |
| Image: |
g01516 P7 |
|
| Specimen Label: |
g01516 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 42 |
| Image: |
g01516 Adult |
|
| Specimen Label: |
g01516 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266523 |
| Pattern: |
Widespread |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945781 |
| Age: |
embryonic day 15.5 |
| Image: |
g01516 E15.5 |
|
| Specimen Label: |
g01516 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133494 |
|
| Specimen Label: |
MRC Harwell_2133494 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945781 |
| Age: |
embryonic day 15.5 |
| Image: |
g01516 E15.5 |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g01516 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 7 |
| Image: |
g01516 P7 |
|
| Specimen Label: |
g01516 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884438 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945781 |
| Age: |
postnatal day 42 |
| Image: |
g01516 Adult |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g01516 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3281228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133498 |
|
| Specimen Label: |
MRC Harwell_2133498 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133491 |
|
| Specimen Label: |
MRC Harwell_2133491 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133492 |
|
| Specimen Label: |
MRC Harwell_2133492 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133495 |
|
| Specimen Label: |
MRC Harwell_2133495 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691687 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133497 |
|
| Specimen Label: |
MRC Harwell_2133497 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
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Vicinanza M |
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2015 |
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Mol Cell |
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•
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•
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| UniProt Feature |
| Begin: |
1 |
| Description: |
Cysteine protease ATG4B |
| Type: |
chain |
| End: |
393 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
120 |
| Description: |
Cleavage; by ATG4B |
| Type: |
site |
| End: |
121 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
116 |
| Description: |
Cleavage; by ATG4B |
| Type: |
site |
| End: |
117 |
|
•
•
•
•
•
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| UniProt Feature |
| Begin: |
116 |
| Description: |
Cleavage; by ATG4B |
| Type: |
site |
| End: |
117 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
120 |
| Description: |
Cleavage; by ATG4B |
| Type: |
site |
| End: |
121 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
116 |
| Description: |
Cleavage; by ATG4B |
| Type: |
site |
| End: |
117 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
393
 |
| Fragment?: |
false |
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Biochem Pharmacol |
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Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia. |
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13 |
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7 |
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| Interaction Experiment |
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Transactivation of Atg4b by C/EBP promotes autophagy to facilitate adipogenesis. |
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Mariño G |
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Bosc D |
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2018 |
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Sci Rep |
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81 |
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9 |
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2031-2040.e8 |
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| Protein Domain |
| Type: |
Family |
| Description: |
ATG4B is one of the four mammalian Atg4 homologues, also known as autophagins, mediating both proteolytic activation and delipidation of ATG8 family proteins [, ]. It is required for Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy []. ATG4B is a cysteine protease required for autophagy and acts to proteolytically prime and recycle its substrate MAP1LC3B (also referred to as LC3), where cleavage generates a C-terminal glycine required for LC3 conjugation to lipids in autophagosomes [, ]. |
|
•
•
•
•
•
|
| Allele |
| Name: |
collagen, type I, alpha 1; targeted mutation 1.1, Bjorn Knollmann |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Inserted expressed sequence, Reporter |
|
•
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•
•
•
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| Strain |
| Attribute String: |
mutant stock, targeted mutation |
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| Year: |
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19 |
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11 |
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2912-2933 |
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Noguera-Ortega E |
| Year: |
2018 |
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Cancer Discov |
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Autophagy in the Tumor or in the Host: Which Plays a Greater Supportive Role? |
| Volume: |
8 |
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3 |
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266-268 |
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Yang A |
| Year: |
2018 |
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Cancer Discov |
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Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. |
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J Biol Chem |
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Structural basis for Ufm1 processing by UfSP1. |
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283 |
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21 |
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| Year: |
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Autophagy |
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