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Search results 101 to 200 out of 1910 for Atoh1

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Type Details Score
Publication
26274331 | J:242777
First Author: Men Y
Year: 2015
Journal: PLoS One
Title: LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice.
Volume: 10
Issue: 8
Pages: e0135841
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Publication
19439493 | J:149533
First Author: Fujiyama T
Year: 2009
Journal: Development
Title: Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1.
Volume: 136
Issue: 12
Pages: 2049-58
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Publication
19782676 | J:154915
First Author: Morrison KM
Year: 2009
Journal: Dev Biol
Title: Mammalian Merkel cells are descended from the epidermal lineage.
Volume: 336
Issue: 1
Pages: 76-83
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Publication
22185794 | J:180770
First Author: Bjerknes M
Year: 2012
Journal: Dev Biol
Title: Origin of the brush cell lineage in the mouse intestinal epithelium.
Volume: 362
Issue: 2
Pages: 194-218
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Publication
26549569 | J:250173
 
First Author: Men Y
Year: 2015
Journal: Sci Rep
Title: LKB1 Regulates Cerebellar Development by Controlling Sonic Hedgehog-mediated Granule Cell Precursor Proliferation and Granule Cell Migration.
Volume: 5
Pages: 16232
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Publication
10383648 | J:56248
First Author: Isaka F
Year: 1999
Journal: Eur J Neurosci
Title: Ectopic expression of the bHLH gene Math1 disturbs neural development.
Volume: 11
Issue: 7
Pages: 2582-8
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Publication
31033441 | J:275835
   
First Author: Jen HI
Year: 2019
Journal: Elife
Title: Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1.
Volume: 8
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Publication
30618612 | J:285518
 
First Author: Zhai X
Year: 2018
Journal: Front Mol Neurosci
Title: Inactivation of Cyclin-Dependent Kinase 5 in Hair Cells Causes Hearing Loss in Mice.
Volume: 11
Pages: 461
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Publication
19243219 | J:145954
First Author: Bossuyt W
Year: 2009
Journal: PLoS Biol
Title: Atonal homolog 1 is a tumor suppressor gene.
Volume: 7
Issue: 2
Pages: e39
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Publication
30063705 | J:265498
First Author: Yamashita T
Year: 2018
Journal: PLoS Genet
Title: High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor.
Volume: 14
Issue: 7
Pages: e1007552
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Publication
27255603 | J:251806
 
First Author: Jin Y
Year: 2016
Journal: Sci Rep
Title: Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea.
Volume: 6
Pages: 27124
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Publication
26988140 | J:251644
 
First Author: Kempfle JS
Year: 2016
Journal: Sci Rep
Title: Sox2 in the differentiation of cochlear progenitor cells.
Volume: 6
Pages: 23293
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Publication
8938455 | J:36536
First Author: Isaka F
Year: 1996
Journal: Genomics
Title: Genetic mapping of four mouse bHLH genes related to Drosophila proneural gene atonal.
Volume: 37
Issue: 3
Pages: 400-2
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Publication
29233556 | J:258780
First Author: Ishibashi F
Year: 2018
Journal: Stem Cell Reports
Title: Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium.
Volume: 10
Issue: 1
Pages: 27-42
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Publication
28450830 | J:274513
 
First Author: Elliott KL
Year: 2017
Journal: Front Neural Circuits
Title: Spiral Ganglion Neuron Projection Development to the Hindbrain in Mice Lacking Peripheral and/or Central Target Differentiation.
Volume: 11
Pages: 25
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Publication
19541997 | J:149981
First Author: Maricich SM
Year: 2009
Journal: Science
Title: Merkel cells are essential for light-touch responses.
Volume: 324
Issue: 5934
Pages: 1580-2
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Publication
19741118 | J:152678
First Author: Maricich SM
Year: 2009
Journal: J Neurosci
Title: Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei.
Volume: 29
Issue: 36
Pages: 11123-33
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Publication
22922422 | J:310681
First Author: Farin HF
Year: 2012
Journal: Gastroenterology
Title: Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells.
Volume: 143
Issue: 6
Pages: 1518-1529.e7
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Publication
35551236 | J:324691
First Author: Jen HI
Year: 2022
Journal: Sci Rep
Title: GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor.
Volume: 12
Issue: 1
Pages: 7793
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Publication
9449674 | J:47081
First Author: Helms AW
Year: 1998
Journal: Development
Title: Progenitors of dorsal commissural interneurons are defined by MATH1 expression.
Volume: 125
Issue: 5
Pages: 919-28
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Publication
28402854 | J:250813
First Author: Walters BJ
Year: 2017
Journal: Cell Rep
Title: In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.
Volume: 19
Issue: 2
Pages: 307-320
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Publication
36445327 | J:339290
   
First Author: Iyer AA
Year: 2022
Journal: Elife
Title: Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals.
Volume: 11
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Publication
18212062 | J:132646
First Author: Chellappa R
Year: 2008
Journal: Mol Cell Biol
Title: Barhl1 regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system.
Volume: 28
Issue: 6
Pages: 1905-14
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Publication
22609550 | J:185870
First Author: Hazen VM
Year: 2012
Journal: Dev Biol
Title: BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord.
Volume: 367
Issue: 2
Pages: 216-27
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Publication
33475140 | J:326576
First Author: Zhang M
Year: 2021
Journal: J Mol Cell Biol
Title: Ablation of Zfhx4 results in early postnatal lethality by disrupting the respiratory center in mice.
Volume: 13
Issue: 3
Pages: 210-224
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Publication
25624394 | J:223960
First Author: Wright MC
Year: 2015
Journal: J Cell Biol
Title: Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.
Volume: 208
Issue: 3
Pages: 367-79
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Publication
19668217 | J:152710
First Author: Aldinger KA
Year: 2009
Journal: Nat Genet
Title: FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.
Volume: 41
Issue: 9
Pages: 1037-42
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Publication
22190634 | J:179656
First Author: VanDussen KL
Year: 2012
Journal: Development
Title: Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.
Volume: 139
Issue: 3
Pages: 488-97
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Publication
23318633 | J:195176
First Author: Driver EC
Year: 2013
Journal: Dev Biol
Title: The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.
Volume: 376
Issue: 1
Pages: 86-98
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Publication
28304405 | J:268432
First Author: Almohazey D
Year: 2017
Journal: Cell Death Differ
Title: The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.
Volume: 24
Issue: 5
Pages: 855-865
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Publication
28892484 | J:264213
First Author: Zhang T
Year: 2017
Journal: PLoS Genet
Title: Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium.
Volume: 13
Issue: 9
Pages: e1006967
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Publication
23533177 | J:195272
First Author: Sipe CW
Year: 2013
Journal: Development
Title: Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.
Volume: 140
Issue: 8
Pages: 1785-95
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Publication
24141309 | J:207638
First Author: Li P
Year: 2013
Journal: Nat Neurosci
Title: A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity.
Volume: 16
Issue: 12
Pages: 1737-44
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Publication
31292434 | J:278397
First Author: Penas C
Year: 2019
Journal: Nat Commun
Title: Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis.
Volume: 10
Issue: 1
Pages: 3028
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Publication
24413398 | J:207494
First Author: Kim TH
Year: 2014
Journal: Nature
Title: Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity.
Volume: 506
Issue: 7489
Pages: 511-5
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Publication
26680304 | J:227404
First Author: Hernandez-Enriquez B
Year: 2015
Journal: Genes Dev
Title: Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing.
Volume: 29
Issue: 24
Pages: 2617-32
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Publication
18272594 | J:132151
First Author: Yamauchi K
Year: 2008
Journal: Development
Title: BMP type I receptor complexes have distinct activities mediating cell fate and axon guidance decisions.
Volume: 135
Issue: 6
Pages: 1119-28
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Publication
30055169 | J:310920
First Author: Gracz AD
Year: 2018
Journal: Gastroenterology
Title: Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates.
Volume: 155
Issue: 5
Pages: 1508-1523.e10
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Publication
15846349 | J:98458
First Author: Kiernan AE
Year: 2005
Journal: Nature
Title: Sox2 is required for sensory organ development in the mammalian inner ear.
Volume: 434
Issue: 7036
Pages: 1031-5
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Publication
31932950 | J:313342
First Author: Nichols DH
Year: 2020
Journal: Cell Tissue Res
Title: Interaction with ectopic cochlear crista sensory epithelium disrupts basal cochlear sensory epithelium development in Lmx1a mutant mice.
Volume: 380
Issue: 3
Pages: 435-448
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Publication
30302725 | J:277666
First Author: Bovio PP
Year: 2019
Journal: Mol Neurobiol
Title: Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo.
Volume: 56
Issue: 6
Pages: 4273-4287
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Publication
35731926 | J:327858
First Author: Yi J
Year: 2022
Journal: Cancer Res
Title: PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma.
Volume: 82
Issue: 16
Pages: 2874-2886
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Publication
36252002 | J:335097
First Author: Qin T
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation.
Volume: 119
Issue: 43
Pages: e2206571119
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Publication
21307253 | J:169455
First Author: Kim D
Year: 2011
Journal: J Neurosci
Title: The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons.
Volume: 31
Issue: 6
Pages: 2167-79
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Publication
33246067 | J:301713
 
First Author: Chizhikov VV
Year: 2021
Journal: Neuroscience
Title: Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System.
Volume: 452
Pages: 247-264
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Publication
25468937 | J:217588
First Author: Perdigoto CN
Year: 2014
Journal: Development
Title: Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network.
Volume: 141
Issue: 24
Pages: 4690-6
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Publication
37585469 | J:345358
First Author: Wang X
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti.
Volume: 120
Issue: 34
Pages: e2301301120
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Publication
25050931 | J:216076
First Author: Hou C
Year: 2014
Journal: Dev Biol
Title: Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.
Volume: 395
Issue: 1
Pages: 167-81
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Publication
37982489 | J:345149
   
First Author: Zhou LY
Year: 2023
Journal: Elife
Title: Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB.
Volume: 12
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Publication
26999738 | J:236644
First Author: Li L
Year: 2016
Journal: Nat Cell Biol
Title: Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.
Volume: 18
Issue: 4
Pages: 418-30
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Publication
33253789 | J:300364
 
First Author: Yi J
Year: 2021
Journal: Cancer Lett
Title: Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma.
Volume: 499
Pages: 188-200
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Publication
22159122 | J:178908
First Author: Okano T
Year: 2011
Journal: J Neurosci
Title: Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.
Volume: 31
Issue: 49
Pages: 18104-18
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Publication
23459943 | J:203750
First Author: Tong KK
Year: 2013
Journal: Mol Cell Biol
Title: Common partner Smad-independent canonical bone morphogenetic protein signaling in the specification process of the anterior rhombic lip during cerebellum development.
Volume: 33
Issue: 10
Pages: 1925-37
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Publication
27559308 | J:273440
 
First Author: Żak M
Year: 2016
Journal: Front Cell Neurosci
Title: LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.
Volume: 10
Pages: 186
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Publication
24431450 | J:205567
First Author: Li K
Year: 2014
Journal: J Neurosci
Title: Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum.
Volume: 34
Issue: 3
Pages: 922-31
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Publication
15186480 | J:91317
First Author: Okubo T
Year: 2004
Journal: J Biol
Title: Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm.
Volume: 3
Issue: 3
Pages: 11
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Publication
21420948 | J:173796
First Author: Yamamoto N
Year: 2011
Journal: Dev Biol
Title: Rbpj regulates development of prosensory cells in the mammalian inner ear.
Volume: 353
Issue: 2
Pages: 367-79
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Publication
26224861 | J:225888
First Author: Kuo BR
Year: 2015
Journal: J Neurosci
Title: In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1.
Volume: 35
Issue: 30
Pages: 10786-98
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Publication
21360794 | J:169673
First Author: Weston MD
Year: 2011
Journal: Dev Dyn
Title: MicroRNA-183 family expression in hair cell development and requirement of microRNAs for hair cell maintenance and survival.
Volume: 240
Issue: 4
Pages: 808-19
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Publication
38688721 | J:351380
 
First Author: Bi Z
Year: 2024
Journal: J Neurosci
Title: Revisiting the Potency of Tbx2 Expression in Transforming Outer Hair Cells into Inner Hair Cells at Multiple Ages In Vivo.
Volume: 44
Issue: 23
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Publication
28729444 | J:248783
First Author: Xie WR
Year: 2017
Journal: J Neurosci
Title: An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.
Volume: 37
Issue: 36
Pages: 8583-8594
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Publication
20661473 | J:220948
First Author: Jahan I
Year: 2010
Journal: PLoS One
Title: Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.
Volume: 5
Issue: 7
Pages: e11661
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Publication
29724954 | J:272030
First Author: Feng J
Year: 2018
Journal: Science
Title: Piezo2 channel-Merkel cell signaling modulates the conversion of touch to itch.
Volume: 360
Issue: 6388
Pages: 530-533
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Publication
38246872 | J:346028
First Author: Tong CK
Year: 2024
Journal: Physiol Rep
Title: Merkel cells and keratinocytes in oral mucosa are activated by mechanical stimulation.
Volume: 12
Issue: 2
Pages: e15826
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Publication
37188723 | J:350052
First Author: van der Heijden ME
Year: 2023
Journal: Nat Commun
Title: Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors.
Volume: 14
Issue: 1
Pages: 2771
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Publication
35238644 | J:321934
First Author: Fu X
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss.
Volume: 119
Issue: 10
Pages: e2107357119
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Publication
30247156 | J:271009
First Author: Fu X
Year: 2018
Journal: J Clin Invest
Title: Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.
Volume: 128
Issue: 11
Pages: 4938-4955
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Publication
23614009 | J:200106
First Author: Duncan JS
Year: 2013
Journal: PLoS One
Title: Continued expression of GATA3 is necessary for cochlear neurosensory development.
Volume: 8
Issue: 4
Pages: e62046
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Publication
23177959 | J:196985
First Author: Yam PT
Year: 2012
Journal: Neuron
Title: 14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing.
Volume: 76
Issue: 4
Pages: 735-49
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Publication
30455179 | J:267832
 
First Author: McInturff S
Year: 2018
Journal: Biol Open
Title: Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers.
Volume: 7
Issue: 11
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Publication
37171961 | J:336865
First Author: Li S
Year: 2023
Journal: Cell Rep
Title: Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development.
Volume: 42
Issue: 5
Pages: 112504
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Publication
37738262 | J:340779
First Author: Di Bonito M
Year: 2023
Journal: PLoS Genet
Title: Abnormal outer hair cell efferent innervation in Hoxb1-dependent sensorineural hearing loss.
Volume: 19
Issue: 9
Pages: e1010933
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Publication
25535838 | J:228845
   
First Author: Kim E
Year: 2014
Journal: Elife
Title: Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.
Volume: 3
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Publication
34857649 | J:352554
First Author: Pop IV
Year: 2022
Journal: J Neurosci
Title: Structure of Long-Range Direct and Indirect Spinocerebellar Pathways as Well as Local Spinal Circuits Mediating Proprioception.
Volume: 42
Issue: 4
Pages: 581-600
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Publication
38627062 | J:349475
 
First Author: Espinosa F
Year: 2024
Journal: eNeuro
Title: Electrophysiological Properties of Proprioception-Related Neurons in the Intermediate Thoracolumbar Spinal Cord.
Volume: 11
Issue: 4
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Publication
30470704 | J:293331
 
First Author: Martinez-Chavez E
Year: 2018
Journal: Development
Title: The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration.
Volume: 145
Issue: 24
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Publication
21693512 | J:173529
First Author: Yu T
Year: 2011
Journal: Development
Title: Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum.
Volume: 138
Issue: 14
Pages: 2957-68
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Publication
29386106 | J:270726
First Author: Shimada IS
Year: 2018
Journal: Cell Rep
Title: Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.
Volume: 22
Issue: 5
Pages: 1169-1184
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Publication
34244441 | J:320548
 
First Author: Li J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.
Volume: 118
Issue: 28
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Publication
30338292 | J:287702
First Author: Zheng H
Year: 2018
Journal: Sci Adv
Title: Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development.
Volume: 4
Issue: 10
Pages: eaat2681
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Protein Coding Gene
MGP_CAROLIEiJ_G0028457 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030806 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_104654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031264 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030493 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030645 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGP_NODShiLtJ_G0030633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGP_NZOHlLtJ_G0031290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
•
•
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Protein Coding Gene
MGP_PWKPhJ_G0029633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGP_WSBEiJ_G0030000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
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Protein Coding Gene
MGP_PahariEiJ_G0022197 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029461 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11918690 | J:75357
First Author: Zhang Y
Year: 2002
Journal: Immunology
Title: Immunoglobulin A-deficient mice exhibit altered T helper 1-type immune responses but retain mucosal immunity to influenza virus.
Volume: 105
Issue: 3
Pages: 286-94
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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