Type |
Details |
Score |
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Andrew Nesbit M |
Year: |
2004 |
Journal: |
Genomics |
Title: |
X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase. |
Volume: |
84 |
Issue: |
6 |
Pages: |
1060-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Q |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
P4-ATPase ATP8A2 acts in synergy with CDC50A to enhance neurite outgrowth. |
Volume: |
586 |
Issue: |
13 |
Pages: |
1803-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Folmer DE |
Year: |
2012 |
Journal: |
J Histochem Cytochem |
Title: |
Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases. |
Volume: |
60 |
Issue: |
3 |
Pages: |
205-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muñoz-MartÃnez F |
Year: |
2010 |
Journal: |
Biochem Pharmacol |
Title: |
CDC50A plays a key role in the uptake of the anticancer drug perifosine in human carcinoma cells. |
Volume: |
80 |
Issue: |
6 |
Pages: |
793-800 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Cell cycle control protein 50A (CDC50A, also known as TMEM30A) is an accessory component of the phospholipid-transporting ATPase (P4-ATPase) complex which catalyses the hydrolysis of ATP coupled to the transport of phospholipids across the membrane []. It can interact with several P4-ATPases, such as ATP8A1, ATP8A2, ATP8B1, ATP8B2, ATP11A, ATP11B and ATP11C [, , ]. CDC50A is a terminal-glycosylated glycoprotein and is expressed in hepatocytes and liver sinusoidal endothelial cells. In pancreas and stomach, it localises to secretory vesicles, while in kidney, it localises to the apical region of proximal convoluted tubules of the cortex []. In human carcinoma cells, CDC50A plays a key role in the uptake of the anticancer drug perifosine []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Liou AY |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. |
Volume: |
294 |
Issue: |
17 |
Pages: |
6809-6821 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyata Y |
Year: |
2022 |
Journal: |
J Biol Chem |
Title: |
Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes. |
Volume: |
298 |
Issue: |
11 |
Pages: |
102527 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kato U |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Role for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migration. |
Volume: |
288 |
Issue: |
7 |
Pages: |
4922-34 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
364
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
328
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Velden LM |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases. |
Volume: |
285 |
Issue: |
51 |
Pages: |
40088-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|