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Search results 101 to 162 out of 162 for Bcar3

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_10
Specimen Label: euxassay_006211_10
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_11
Specimen Label: euxassay_006211_11
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_12
Specimen Label: euxassay_006211_12
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_13
Specimen Label: euxassay_006211_13
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_14
Specimen Label: euxassay_006211_14
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5433068
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5433153
Age: embryonic day 13.5
Specimen Label: 3C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5433068
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5433153
Age: embryonic day 12.0
Specimen Label: 3D - XY
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_08
Specimen Label: euxassay_006211_08
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_09
Specimen Label: euxassay_006211_09
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_10
Specimen Label: euxassay_006211_10
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_15
Specimen Label: euxassay_006211_15
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_16
Specimen Label: euxassay_006211_16
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:936525
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823439
Age: embryonic day 14.5
Image: euxassay_006211_17
Specimen Label: euxassay_006211_17
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
     
Probe: MGI:5433125
Assay Type: RNA in situ
Annotation Date: 2012-09-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5433131
Age: embryonic day 11.5
Specimen Label: XY
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5433125
Assay Type: RNA in situ
Annotation Date: 2012-09-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5433131
Age: embryonic day 11.5
Specimen Label: XX
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5433125
Assay Type: RNA in situ
Annotation Date: 2012-09-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5433131
Age: embryonic day 12.5
Specimen Label: XX
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5433125
Assay Type: RNA in situ
Annotation Date: 2012-09-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5433131
Age: embryonic day 13.5
Specimen Label: XX
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5433152
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5433159
Age: embryonic day 12.5
Specimen Label: 3B - X
Detected: false
Specimen Num: 2
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Publication
10438950 | J:56740
First Author: Cai D
Year: 1999
Journal: J Immunol
Title: AND-34, a novel p130Cas-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines.
Volume: 163
Issue: 4
Pages: 2104-12
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
17270363 | -
First Author: Vervoort VS
Year: 2007
Journal: Gene
Title: Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling.
Volume: 391
Issue: 1-2
Pages: 161-70
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Publication
9817027 | -
First Author: Sawyer TK
Year: 1998
Journal: Biopolymers
Title: Src homology-2 domains: structure, mechanisms, and drug discovery.
Volume: 47
Issue: 3
Pages: 243-61
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Protein Domain
IPR044102 | SH2_SHEP1/BCAR3/NSP1
Type: Domain
Description: Breast cancer anti-estrogen resistance protein 3 (BCAR3) is an SH2-containing signal transducer that regulates the proliferation in breast cancer cells []. BCAR3 binds to the adaptor molecule p130Cas (also known as BCAR1), which function as key signalling nodes with important regulatory roles in normal and pathological cells []. BCAR3 promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells []. It also promotes interactions between p130Cas and the protein tyrosine kinase c-Src, leading to increased c-Src kinase activity and p130Cas phosphorylation [].This entry represents the SH2 domain found in SHEP1 (also known as SH2D3C), BCAR3 and NSP1 (also known as SH2D3A). SHEP1, BCAR3 and NSP1 are cytoplasmic proteins involved in cell adhesion/migration and antiestrogen resistance. All three proteins contain an SH2 domain and an exchange factor-like domain that binds both Ras GTPases and the scaffolding protein Cas []. In general, SH2 domains are involved in signal transduction. They typically bind pTyr-containing ligands via two surface pockets, a pTyr and hydrophobic binding pocket, allowing proteins with SH2 domains to localize to tyrosine phosphorylated sites [].
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Protein
Q9QZS8
Organism: Mus musculus/domesticus
Length: 854  
Fragment?: false
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