|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 169 out of 169 for Bckdk

<< First    < Previous  |  Next >    Last >>
0.026s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
•
•
•
•
•
Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
39709505 | J:360799
First Author: Jishi A
Year: 2024
Journal: Acta Neuropathol Commun
Title: BCKDK loss impairs mitochondrial Complex I activity and drives alpha-synuclein aggregation in models of Parkinson's disease.
Volume: 12
Issue: 1
Pages: 198
•
•
•
•
•
Allele
Bckdk<em2Smoc> | MGI:7288449
Name: branched chain ketoacid dehydrogenase kinase; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Publication
24449431 | -
First Author: García-Cazorla A
Year: 2014
Journal: Hum Mutat
Title: Two novel mutations in the BCKDK (branched-chain keto-acid dehydrogenase kinase) gene are responsible for a neurobehavioral deficit in two pediatric unrelated patients.
Volume: 35
Issue: 4
Pages: 470-7
•
•
•
•
•
DO Term
DOID:0090126 | branched-chain keto acid dehydrogenase kinase deficiency
•
•
•
•
•
Allele
Bckdk<em1Smoc> | MGI:7288448
Name: branched chain ketoacid dehydrogenase kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
HT Experiment
E-GEOD-39447 | Mutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsy
Series Id: GSE39447
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Strain
MGI:6474851 | C57BL/6JSmoc-Bckdk<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Publication
11486000 | -
First Author: Korotchkina LG
Year: 2001
Journal: J Biol Chem
Title: Site specificity of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase.
Volume: 276
Issue: 40
Pages: 37223-9
•
•
•
•
•
Protein Domain
IPR039028 | BCKD/PDK
Type: Family
Description: This entry includes [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]]kinase (BCKDK) and [Pyruvate dehydrogenase (acetyl-transferring)]kinase (PDK). BCKDK catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways [].Pyruvatedehydrogenase kinase inhibits the pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism [].
•
•
•
•
•
Protein
Q8BFP4
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
•
•
•
•
•
Protein
G3BKC4
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
•
•
•
•
•
Protein
A0A0U1RQ50
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
•
•
•
•
•
Publication
31167878 | J:278918
First Author: Zhou M
Year: 2019
Journal: Diabetes
Title: Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance.
Volume: 68
Issue: 9
Pages: 1730-1746
•
•
•
•
•
Publication
30808755 | J:273879
First Author: Cheon S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The ubiquitin ligase UBE3B, disrupted in intellectual disability and absent speech, regulates metabolic pathways by targeting BCKDK.
Volume: 116
Issue: 9
Pages: 3662-3667
•
•
•
•
•
Publication
32878988 | J:300470
First Author: Biswas D
Year: 2020
Journal: J Biol Chem
Title: Branched-chain ketoacid overload inhibits insulin action in the muscle.
Volume: 295
Issue: 46
Pages: 15597-15621
•
•
•
•
•
Protein
A0A0N4SW53
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: true
•
•
•
•
•
Protein
D3Z7R0
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
•
•
•
•
•
Protein
A0A0U1RQ97
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: true
•
•
•
•
•
Protein
Q3V250
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
•
•
•
•
•
Protein
A0A0U1RPT4
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
•
•
•
•
•
Protein
A0A0U1RNL7
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
•
•
•
•
•
Protein
Q922H2
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
•
•
•
•
•
Protein
Q9JK42
Organism: Mus musculus/domesticus
Length: 407  
Fragment?: false
•
•
•
•
•
Protein
O70571
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
•
•
•
•
•
Protein
Q8BFP9
Organism: Mus musculus/domesticus
Length: 434  
Fragment?: false
•
•
•
•
•
Protein
Q8R2U8
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: false
•
•
•
•
•
Protein
Q544J2
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
•
•
•
•
•
Protein
Q4FJR4
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
•
•
•
•
•
Protein
O55028
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
•
•
•
•
•
Protein
Q99KP1
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: true
•
•
•
•
•
Protein
Q3UCB5
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
•
•
•
•
•
Protein
Q8C6H9
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
•
•
•
•
•
Protein
Q3UC13
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom