Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:4417718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:2760523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4823453 |
Age: |
embryonic day 14.5 |
Image: |
5A |
|
Specimen Label: |
5A |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1897623 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4823453 |
Age: |
embryonic day 14.5 |
Image: |
5A |
Note: |
Expression was not detected in the proximal tubules. |
Specimen Label: |
5A |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:4823453 |
Age: |
embryonic day 14.5 |
Image: |
Table S8 |
|
Specimen Label: |
Table S8 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:4823453 |
Age: |
embryonic day 14.5 |
Image: |
Table S8 |
|
Specimen Label: |
Table S8 |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6468560 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-26 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6469290 |
Age: |
postnatal day 24-28 |
Image: |
S2D cKO |
Note: |
Expression is seen in the Golgi complex of metaphase II (MII) oocytes. |
Specimen Label: |
S2D cKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6468560 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-10-26 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6469290 |
Age: |
postnatal day 24-28 |
Image: |
S2D Control |
Note: |
Expression is seen in the Golgi complex of metaphase II (MII) oocytes. |
Specimen Label: |
S2D Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1821523 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:4823453 |
Age: |
embryonic day 14.5 |
Image: |
Table S8 |
|
Specimen Label: |
Table S8 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4417718 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:4823453 |
Age: |
embryonic day 14.5 |
Image: |
Table S8 |
|
Specimen Label: |
Table S8 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6506634 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-02-17 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3670517 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6506827 |
Age: |
embryonic day 10.5 |
|
Note: |
Highly expressed in invaginating head surface ectoderm. |
Specimen Label: |
S4 Bcl9-IHC E10.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6506634 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2021-02-17 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3670517 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:6506827 |
Age: |
embryonic day 10.5 |
|
Note: |
Ectodermal expression strongly reduced compared with wild-type embryos. |
Specimen Label: |
Pax6-Sey not shown |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lerer-Goldshtein T |
Year: |
2010 |
Journal: |
Dev Biol |
Title: |
TMF/ARA160: A key regulator of sperm development. |
Volume: |
348 |
Issue: |
1 |
Pages: |
12-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deka J |
Year: |
2010 |
Journal: |
Cancer Res |
Title: |
Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. |
Volume: |
70 |
Issue: |
16 |
Pages: |
6619-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei JH |
Year: |
2015 |
Journal: |
Cell |
Title: |
GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules. |
Volume: |
162 |
Issue: |
2 |
Pages: |
287-299 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borrelli C |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells. |
Volume: |
12 |
Issue: |
1 |
Pages: |
1368 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ahmedli NB |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa. |
Volume: |
288 |
Issue: |
14 |
Pages: |
9742-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adachi S |
Year: |
2004 |
Journal: |
Cancer Res |
Title: |
Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. |
Volume: |
64 |
Issue: |
23 |
Pages: |
8496-501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liegel RP |
Year: |
2013 |
Journal: |
Am J Hum Genet |
Title: |
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. |
Volume: |
93 |
Issue: |
6 |
Pages: |
1001-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gay DM |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer. |
Volume: |
10 |
Issue: |
1 |
Pages: |
723 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki T |
Year: |
2023 |
Journal: |
Cancer Immunol Res |
Title: |
β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer. |
Volume: |
11 |
Issue: |
8 |
Pages: |
1137-1155 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fusco C |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. |
Volume: |
7 |
Issue: |
7 |
Pages: |
e40440 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu C |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes. |
Volume: |
20 |
Issue: |
5 |
Pages: |
1161-1172 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shull LC |
Year: |
2022 |
Journal: |
Development |
Title: |
PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation. |
Volume: |
149 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Brici D |
Year: |
2017 |
Journal: |
Development |
Title: |
Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program. |
Volume: |
144 |
Issue: |
14 |
Pages: |
2606-2617 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weberling A |
Year: |
2025 |
Journal: |
iScience |
Title: |
Primitive to visceral endoderm maturation is essential for mouse epiblast survival beyond implantation. |
Volume: |
28 |
Issue: |
1 |
Pages: |
111671 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thuret S |
Year: |
2004 |
Journal: |
Mol Cell Neurosci |
Title: |
Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. |
Volume: |
25 |
Issue: |
3 |
Pages: |
394-405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martinez G |
Year: |
2009 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. |
Volume: |
50 |
Issue: |
10 |
Pages: |
4794-806 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang M |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins. |
Volume: |
11 |
Issue: |
1 |
Pages: |
19 |
|
•
•
•
•
•
|
Allele |
Name: |
B cell CLL/lymphoma 9; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Sampietro J |
Year: |
2006 |
Journal: |
Mol Cell |
Title: |
Crystal structure of a beta-catenin/BCL9/Tcf4 complex. |
Volume: |
24 |
Issue: |
2 |
Pages: |
293-300 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
259
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
90
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Willis TG |
Year: |
1998 |
Journal: |
Blood |
Title: |
Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21. |
Volume: |
91 |
Issue: |
6 |
Pages: |
1873-81 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
BCL9 is associated with B-cell acute lymphoblastic leukemia []. This entry includes BCL9 and BCL9L. They are tissue-specific transcriptional cofactors that cooperate with beta-catenin. In the nucleus, Bcl9 and Bcl9l simultaneously bind beta-catenin and the transcriptional activator Pygo2 to promote the transcription of a subset of Wnt target genes. They may also have a cytoplasmic role []. |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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Protein Domain |
Type: |
Domain |
Description: |
The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis.B-cell lymphoma 9 (BCL9) associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes [].This entry represents a beta-catenin binding domain found in BCL9 and BCL9 homologues. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1494
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1425
 |
Fragment?: |
false |
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Publication |
First Author: |
Kennedy JC |
Year: |
2019 |
Journal: |
Hum Mol Genet |
Title: |
Loss of FLCN inhibits canonical WNT signaling via TFE3. |
Volume: |
28 |
Issue: |
19 |
Pages: |
3270-3281 |
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Publication |
First Author: |
Buechel D |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Parsing β-catenin's cell adhesion and Wnt signaling functions in malignant mammary tumor progression. |
Volume: |
118 |
Issue: |
34 |
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