Type |
Details |
Score |
Publication |
First Author: |
Vince JE |
Year: |
2012 |
Journal: |
Immunity |
Title: |
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. |
Volume: |
36 |
Issue: |
2 |
Pages: |
215-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lawlor KE |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. |
Volume: |
6 |
|
Pages: |
6282 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song H |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. |
Volume: |
107 |
Issue: |
4 |
Pages: |
1431-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Götz R |
Year: |
2005 |
Journal: |
Nat Neurosci |
Title: |
Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells. |
Volume: |
8 |
Issue: |
9 |
Pages: |
1169-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koide M |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells. |
Volume: |
108 |
Issue: |
23 |
Pages: |
9472-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu X |
Year: |
2009 |
Journal: |
Diabetologia |
Title: |
Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice. |
Volume: |
52 |
Issue: |
10 |
Pages: |
2130-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robert-Moreno A |
Year: |
2007 |
Journal: |
Leukemia |
Title: |
The notch pathway positively regulates programmed cell death during erythroid differentiation. |
Volume: |
21 |
Issue: |
7 |
Pages: |
1496-503 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soma S |
Year: |
2024 |
Journal: |
Stem Cells |
Title: |
O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. |
Volume: |
42 |
Issue: |
1 |
Pages: |
55-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reed JC |
Year: |
2003 |
Journal: |
Genome Res |
Title: |
Comparative analysis of apoptosis and inflammation genes of mice and humans. |
Volume: |
13 |
Issue: |
6B |
Pages: |
1376-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Papin J |
Year: |
2004 |
Journal: |
Curr Opin Biotechnol |
Title: |
Bioinformatics and cellular signaling. |
Volume: |
15 |
Issue: |
1 |
Pages: |
78-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain is found in TNF receptor-associated factor 1 and 2 (TRAF1 and TRAF2), where it binds to Baculoviral IAP repeat-containing protein 3 (BIRC3) (cIAP2) []. |
|
•
•
•
•
•
|
Allele |
Name: |
baculoviral IAP repeat-containing 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
600
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
255
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng C |
Year: |
2010 |
Journal: |
Mol Cell |
Title: |
Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. |
Volume: |
38 |
Issue: |
1 |
Pages: |
101-13 |
|
•
•
•
•
•
|
Allele |
Name: |
baculoviral IAP repeat-containing 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
409
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
baculoviral IAP repeat-containing 2; endonuclease-mediated mutation 1, Hamid Kashkar |
Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
Allele |
Name: |
baculoviral IAP repeat-containing 3; endonuclease-mediated mutation 1, Hamid Kashkar |
Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Yasuma T |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
Amelioration of Diabetes by Protein S. |
Volume: |
65 |
Issue: |
7 |
Pages: |
1940-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Puto LA |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation. |
Volume: |
22 |
Issue: |
8 |
Pages: |
998-1010 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim TH |
Year: |
2013 |
Journal: |
Cancer Res |
Title: |
Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer. |
Volume: |
73 |
Issue: |
16 |
Pages: |
5090-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dubrez-Daloz L |
Year: |
2008 |
Journal: |
Cell Cycle |
Title: |
IAPs: more than just inhibitors of apoptosis proteins. |
Volume: |
7 |
Issue: |
8 |
Pages: |
1036-46 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
138
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kulathila R |
Year: |
2009 |
Journal: |
Acta Crystallogr D Biol Crystallogr |
Title: |
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9. |
Volume: |
65 |
Issue: |
Pt 1 |
Pages: |
58-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dueber EC |
Year: |
2011 |
Journal: |
Science |
Title: |
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. |
Volume: |
334 |
Issue: |
6054 |
Pages: |
376-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Damgaard RB |
Year: |
2011 |
Journal: |
Discov Med |
Title: |
Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity. |
Volume: |
11 |
Issue: |
58 |
Pages: |
221-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cartier J |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription. |
Volume: |
286 |
Issue: |
30 |
Pages: |
26406-17 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
The entry represents the UBA domain found in c-IAPs, including BIRC2 (also known as C-IAP1) and BIRC3 (also known as C-IAP2). c-IAPs function as ubiquitin E3 ligases that mediate the ubiquitination of the substrates involved in apoptosis, nuclear factor-kappaB (NF-kappaB) signaling, and oncogenesis [, ]. Unlike other apoptosis proteins such as XIAP, c-IAPs exhibit minimal binding to caspases and may not play an important role in the inhibition of these proteases. c-IAP1 is a potent regulator of the tumor necrosis factor (TNF) receptor family and NF-kappaB signaling pathways in the cytoplasm. It can also regulate E2F1 transcription factor-mediated control of cyclin transcription in the nucleus []. c-IAP2 also influences ubiquitin-dependent pathways that modulate innate immune signalling by activation of NF-kappaB []. c-IAPs contain three N-terminal baculoviral IAP repeat (BIR) domains that enable interactions with proteins, a ubiquitin-association (UBA) domain that is responsible for the binding of polyubiquitin (polyUb), a caspase activation and recruitment domain (CARD) that serves as a protein interaction surface, and a RING domain at the carboxyl terminus that is required for ubiquitin ligase activity [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Gyrd-Hansen M |
Year: |
2010 |
Journal: |
Nat Rev Cancer |
Title: |
IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. |
Volume: |
10 |
Issue: |
8 |
Pages: |
561-74 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
542
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
545
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
612
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
602
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|