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Search results 101 to 193 out of 193 for Blnk

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1800267
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823479
Age: embryonic day 14.5
Image: euxassay_002437_18
Specimen Label: euxassay_002437_18
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1800267
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823479
Age: embryonic day 14.5
Image: euxassay_002437_19
Specimen Label: euxassay_002437_19
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:1800267
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823479
Age: embryonic day 14.5
Image: euxassay_002437_20
Specimen Label: euxassay_002437_20
Detected: true
Specimen Num: 12
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Publication
- | J:66177
   
First Author: Kitamura D
Year: 1999
Journal: GenBank Submission
Title: Mus musculus mRNA for BASH, complete cds
Pages: AB015290
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Publication
15549729 | J:94601
First Author: Su YW
Year: 2004
Journal: Eur J Immunol
Title: The molecular requirements for LAT-mediated differentiation and the role of LAT in limiting pre-B cell expansion.
Volume: 34
Issue: 12
Pages: 3614-22
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Publication
12932362 | J:85187
First Author: Su YW
Year: 2003
Journal: Immunity
Title: LAT links the pre-BCR to calcium signaling.
Volume: 19
Issue: 2
Pages: 295-305
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Publication
12818163 | J:84040
First Author: Hayashi K
Year: 2003
Journal: Immunity
Title: Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors.
Volume: 18
Issue: 6
Pages: 825-36
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Publication
20133609 | J:157575
First Author: Duchez S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.
Volume: 107
Issue: 7
Pages: 3064-9
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Publication
14694181 | J:88628
First Author: Nichols KE
Year: 2004
Journal: J Leukoc Biol
Title: Macrophage activation and Fcgamma receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors.
Volume: 75
Issue: 3
Pages: 541-52
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Publication
20818374 | J:164431
First Author: Yang J
Year: 2010
Journal: Nature
Title: Oligomeric organization of the B-cell antigen receptor on resting cells.
Volume: 467
Issue: 7314
Pages: 465-9
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Publication
21822214 | J:175996
First Author: Oellerich T
Year: 2011
Journal: EMBO J
Title: The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.
Volume: 30
Issue: 17
Pages: 3620-34
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Publication
11449370 | J:70406
First Author: Jumaa H
Year: 2001
Journal: Eur J Immunol
Title: The absence of SLP65 and Btk blocks B cell development at the preB cell receptor-positive stage.
Volume: 31
Issue: 7
Pages: 2164-9
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Publication
14638847 | J:86804
First Author: Su YW
Year: 2003
Journal: J Exp Med
Title: Identification of a pre-BCR lacking surrogate light chain.
Volume: 198
Issue: 11
Pages: 1699-706
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Publication
19620627 | J:151545
First Author: Trageser D
Year: 2009
Journal: J Exp Med
Title: Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.
Volume: 206
Issue: 8
Pages: 1739-53
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Publication
16481047 | J:143854
First Author: Nojima T
Year: 2006
Journal: Immunol Lett
Title: Double knockout mice show BASH and PKCdelta have different epistatic relationships in B cell maturation and CD40-mediated activation.
Volume: 105
Issue: 1
Pages: 48-54
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Publication
23066158 | J:190706
First Author: Ta VB
Year: 2012
Journal: J Immunol
Title: Highly restricted usage of Ig H chain VH14 family gene segments in Slp65-deficient pre-B cell leukemia in mice.
Volume: 189
Issue: 10
Pages: 4842-51
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Publication
12835482 | J:84461
First Author: Kersseboom R
Year: 2003
Journal: J Exp Med
Title: Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.
Volume: 198
Issue: 1
Pages: 91-8
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Publication
15331445 | J:94768
First Author: Middendorp S
Year: 2005
Journal: Blood
Title: Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity.
Volume: 105
Issue: 1
Pages: 259-65
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Publication
21930792 | J:178776
First Author: Draber P
Year: 2011
Journal: Mol Cell Biol
Title: SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Volume: 31
Issue: 22
Pages: 4550-62
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Publication
17164342 | J:145344
First Author: Xu S
Year: 2007
Journal: Blood
Title: Combined deficiencies in Bruton tyrosine kinase and phospholipase Cgamma2 arrest B-cell development at a pre-BCR+ stage.
Volume: 109
Issue: 8
Pages: 3377-84
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Publication
16585544 | J:131167
First Author: Kersseboom R
Year: 2006
Journal: J Immunol
Title: Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.
Volume: 176
Issue: 8
Pages: 4543-52
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Publication
22949502 | J:189244
First Author: Kawano Y
Year: 2012
Journal: Mol Cell Biol
Title: A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 5.
Volume: 32
Issue: 21
Pages: 4462-71
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Publication
24888588 | J:211639
First Author: Rosenbaum M
Year: 2014
Journal: Genes Dev
Title: MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress.
Volume: 28
Issue: 11
Pages: 1165-78
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Publication
24558349 | J:208412
First Author: Stadhouders R
Year: 2014
Journal: PLoS Biol
Title: Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.
Volume: 12
Issue: 2
Pages: e1001791
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Publication
27428827 | J:258702
First Author: Haniuda K
Year: 2016
Journal: Nat Immunol
Title: Autonomous membrane IgE signaling prevents IgE-memory formation.
Volume: 17
Issue: 9
Pages: 1109-17
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Publication
20008789 | J:157728
First Author: Ta VB
Year: 2010
Journal: Blood
Title: Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway.
Volume: 115
Issue: 7
Pages: 1385-93
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Publication
17681949 | J:125381
First Author: Abudula A
Year: 2007
Journal: J Biol Chem
Title: SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk.
Volume: 282
Issue: 39
Pages: 29059-66
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Publication
17277139 | J:143982
First Author: Herzog S
Year: 2007
Journal: J Immunol
Title: The N terminus of the non-T cell activation linker (NTAL) confers inhibitory effects on pre-B cell differentiation.
Volume: 178
Issue: 4
Pages: 2336-43
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Publication
28290451 | J:276512
First Author: Luo L
Year: 2017
Journal: Immunol Cell Biol
Title: Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP.
Volume: 95
Issue: 6
Pages: 564-570
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Publication
15879130 | J:99047
First Author: Borsutzky S
Year: 2005
Journal: J Immunol
Title: The mucosal adjuvant macrophage-activating lipopeptide-2 directly stimulates B lymphocytes via the TLR2 without the need of accessory cells.
Volume: 174
Issue: 10
Pages: 6308-13
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Publication
21030983 | J:167638
First Author: Ta VB
Year: 2011
Journal: Leukemia
Title: Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.
Volume: 25
Issue: 1
Pages: 48-56
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Publication
28628091 | J:258991
First Author: Dolezal E
Year: 2017
Journal: Nat Immunol
Title: The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.
Volume: 18
Issue: 8
Pages: 911-920
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Publication
20498019 | J:163422
First Author: Duy C
Year: 2010
Journal: J Exp Med
Title: BCL6 is critical for the development of a diverse primary B cell repertoire.
Volume: 207
Issue: 6
Pages: 1209-21
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Publication
26522721 | J:227904
First Author: Hiratsuka T
Year: 2016
Journal: Oncogene
Title: ZFP521 contributes to pre-B-cell lymphomagenesis through modulation of the pre-B-cell receptor signaling pathway.
Volume: 35
Issue: 25
Pages: 3227-38
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Publication
18329366 | J:135537
First Author: Shinohara M
Year: 2008
Journal: Cell
Title: Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.
Volume: 132
Issue: 5
Pages: 794-806
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Publication
25759025 | J:219919
First Author: Geng H
Year: 2015
Journal: Cancer Cell
Title: Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.
Volume: 27
Issue: 3
Pages: 409-25
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Publication
21856866 | J:178400
First Author: Nahar R
Year: 2011
Journal: Blood
Title: Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.
Volume: 118
Issue: 15
Pages: 4174-8
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Publication
12176364 | J:230362
First Author: Berry DM
Year: 2002
Journal: Curr Biol
Title: A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.
Volume: 12
Issue: 15
Pages: 1336-41
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Publication
21464221 | J:177319
First Author: Bhattacharyya S
Year: 2011
Journal: J Exp Med
Title: NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network.
Volume: 208
Issue: 4
Pages: 823-39
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Publication
1460423 | J:3304
First Author: Watson ML
Year: 1992
Journal: J Exp Med
Title: Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
Volume: 176
Issue: 6
Pages: 1645-56
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Publication
1358795 | J:2171
First Author: Rochelle JM
Year: 1992
Journal: Genomics
Title: A linkage map of mouse chromosome 19: definition of comparative mapping relationships with human chromosomes 10 and 11 including the MEN1 locus.
Volume: 14
Issue: 1
Pages: 26-31
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Publication
8499657 | J:4593
First Author: Eicher EM
Year: 1993
Journal: Mamm Genome
Title: Corrected centromere orientation for mouse chromosome 19 MIT markers.
Volume: 4
Issue: 4
Pages: 223-5
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Publication
15733672 | J:96550
First Author: Williams TM
Year: 2005
Journal: Dev Biol
Title: Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.
Volume: 279
Issue: 2
Pages: 462-80
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Publication
25331958 | J:218799
First Author: Yoon J
Year: 2014
Journal: J Biol Chem
Title: Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR.
Volume: 289
Issue: 49
Pages: 34250-7
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Publication
15196959 | J:91443
First Author: Wilm B
Year: 2004
Journal: Dev Biol
Title: The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate.
Volume: 271
Issue: 1
Pages: 176-89
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Publication
22761313 | J:185495
First Author: Arnold CN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Volume: 109
Issue: 31
Pages: 12286-93
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Publication
1431091 | J:3170
First Author: Morse HC 3rd
Year: 1992
Journal: J Immunol
Title: Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells.
Volume: 149
Issue: 10
Pages: 3129-34
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0060027 | agammaglobulinemia 4
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UniProt Feature
UniProt Feature
Begin: 204
Description: Required for binding to BLNK
Type: site
End: 204
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Publication
11909947 | -
First Author: Kabak S
Year: 2002
Journal: Mol Cell Biol
Title: The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways.
Volume: 22
Issue: 8
Pages: 2524-35
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Allele
Blnk<tm1Achn> | MGI:2389137
Name: B cell linker; targeted mutation 1, Andrew C Chan
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:2389139 | B6.129-Blnk<tm1Achn>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Blnk/Blnk
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Blnk/Blnk<+>
Background: involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Blnk/Blnk<+> Btk/Btk Tg(IGH-Btk)1Witt/?
Background: involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
10229183 | J:88257
First Author: Garrett-Sinha LA
Year: 1999
Journal: Immunity
Title: PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction.
Volume: 10
Issue: 4
Pages: 399-408
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Publication
17493844 | J:123596
First Author: Kitaura Y
Year: 2007
Journal: Immunity
Title: Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.
Volume: 26
Issue: 5
Pages: 567-78
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Publication
26834154 | J:232629
First Author: Bednarski JJ
Year: 2016
Journal: J Exp Med
Title: RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.
Volume: 213
Issue: 2
Pages: 209-23
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Publication
22267219 | J:181283
First Author: Ochiai K
Year: 2012
Journal: Nat Immunol
Title: A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Volume: 13
Issue: 3
Pages: 300-7
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Publication
15199160 | J:91590
First Author: Utting O
Year: 2004
Journal: Mol Cell Biol
Title: Immune functions in mice lacking Clnk, an SLP-76-related adaptor expressed in a subset of immune cells.
Volume: 24
Issue: 13
Pages: 6067-75
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Publication
20876806 | J:164646
First Author: Gruber TA
Year: 2010
Journal: Cancer Res
Title: Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.
Volume: 70
Issue: 19
Pages: 7411-20
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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