Type |
Details |
Score |
Publication |
First Author: |
Wang L |
Year: |
2013 |
Journal: |
EMBO J |
Title: |
BRCA1 is a negative modulator of the PRC2 complex. |
Volume: |
32 |
Issue: |
11 |
Pages: |
1584-97 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Khavari PA |
Year: |
1993 |
Journal: |
Nature |
Title: |
BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. |
Volume: |
366 |
Issue: |
6451 |
Pages: |
170-4 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
462
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
462
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu X |
Year: |
2003 |
Journal: |
Science |
Title: |
The BRCT domain is a phospho-protein binding domain. |
Volume: |
302 |
Issue: |
5645 |
Pages: |
639-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dong Y |
Year: |
2003 |
Journal: |
Mol Cell |
Title: |
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. |
Volume: |
12 |
Issue: |
5 |
Pages: |
1087-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miao K |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. |
Volume: |
11 |
Issue: |
1 |
Pages: |
3256 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nacson J |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance. |
Volume: |
24 |
Issue: |
13 |
Pages: |
3513-3527.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gowen LC |
Year: |
1996 |
Journal: |
Nat Genet |
Title: |
Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. |
Volume: |
12 |
Issue: |
2 |
Pages: |
191-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vasanthakumar A |
Year: |
2016 |
Journal: |
Blood |
Title: |
Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice. |
Volume: |
127 |
Issue: |
3 |
Pages: |
310-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng CX |
Year: |
2001 |
Journal: |
Mutat Res |
Title: |
Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice. |
Volume: |
477 |
Issue: |
1-2 |
Pages: |
183-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao VN |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts. |
Volume: |
12 |
Issue: |
3 |
Pages: |
523-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berton TR |
Year: |
2003 |
Journal: |
Oncogene |
Title: |
Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues. |
Volume: |
22 |
Issue: |
35 |
Pages: |
5415-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Phillips KW |
Year: |
1997 |
Journal: |
Lab Invest |
Title: |
Brca1 is expressed independently of hormonal stimulation in the mouse ovary. |
Volume: |
76 |
Issue: |
3 |
Pages: |
419-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moynahan ME |
Year: |
2002 |
Journal: |
Oncogene |
Title: |
The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans. |
Volume: |
21 |
Issue: |
58 |
Pages: |
8994-9007 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2019 |
Journal: |
Cell |
Title: |
Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer. |
Volume: |
178 |
Issue: |
1 |
Pages: |
135-151.e19 |
|
•
•
•
•
•
|
Publication |
First Author: |
McAllister KA |
Year: |
2002 |
Journal: |
Breast Cancer Res |
Title: |
Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related? |
Volume: |
4 |
Issue: |
2 |
Pages: |
54-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng CX |
Year: |
2003 |
Journal: |
Hum Mol Genet |
Title: |
Roles of BRCA1 in DNA damage repair: a link between development and cancer. |
Volume: |
12 Spec No 1 |
|
Pages: |
R113-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen KS |
Year: |
1996 |
Journal: |
Carcinogenesis |
Title: |
Cloning, genetic mapping and expression studies of the rat Brca1 gene. |
Volume: |
17 |
Issue: |
8 |
Pages: |
1561-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arlt MF |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function. |
Volume: |
24 |
Issue: |
15 |
Pages: |
6701-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bennett LM |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
Sequence analysis of the rat Brca1 homolog and its promoter region. |
Volume: |
10 |
Issue: |
1 |
Pages: |
19-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jackson KC |
Year: |
2014 |
Journal: |
J Lipid Res |
Title: |
BRCA1 is a novel regulator of metabolic function in skeletal muscle. |
Volume: |
55 |
Issue: |
4 |
Pages: |
668-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lowndes NF |
Year: |
2010 |
Journal: |
DNA Repair (Amst) |
Title: |
The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1112-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
DeGregorio L |
Year: |
1996 |
Journal: |
Mamm Genome |
Title: |
Genetic mapping of the Brca1 gene on mouse chromosome 11. |
Volume: |
7 |
Issue: |
3 |
Pages: |
242 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bachelier R |
Year: |
2005 |
Journal: |
Oncol Rep |
Title: |
Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice. |
Volume: |
14 |
Issue: |
5 |
Pages: |
1117-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bachelier R |
Year: |
2003 |
Journal: |
Oncogene |
Title: |
Normal lymphocyte development and thymic lymphoma formation in Brca1 exon-11-deficient mice. |
Volume: |
22 |
Issue: |
4 |
Pages: |
528-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorrini C |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival. |
Volume: |
210 |
Issue: |
8 |
Pages: |
1529-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brodie SG |
Year: |
2001 |
Journal: |
Oncogene |
Title: |
Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice. |
Volume: |
20 |
Issue: |
51 |
Pages: |
7514-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiang HC |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Drake DM |
Year: |
2021 |
Journal: |
Redox Biol |
Title: |
Novel mechanisms in alcohol neurodevelopmental disorders via BRCA1 depletion and BRCA1-dependent NADPH oxidase regulation. |
Volume: |
48 |
|
Pages: |
102148 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng CX |
Year: |
2000 |
Journal: |
Oncogene |
Title: |
Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation. |
Volume: |
19 |
Issue: |
8 |
Pages: |
1059-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pageau GJ |
Year: |
2006 |
Journal: |
J Cell Biol |
Title: |
BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin. |
Volume: |
175 |
Issue: |
5 |
Pages: |
693-701 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1811
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Bunting SF |
Year: |
2012 |
Journal: |
Mol Cell |
Title: |
BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. |
Volume: |
46 |
Issue: |
2 |
Pages: |
125-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu X |
Year: |
1999 |
Journal: |
Nat Genet |
Title: |
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. |
Volume: |
22 |
Issue: |
1 |
Pages: |
37-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Drost R |
Year: |
2011 |
Journal: |
Cancer Cell |
Title: |
BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance. |
Volume: |
20 |
Issue: |
6 |
Pages: |
797-809 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernard-Gallon DJ |
Year: |
2001 |
Journal: |
Int J Oncol |
Title: |
Brca1 and Brca2 protein expression patterns in different tissues of murine origin. |
Volume: |
18 |
Issue: |
2 |
Pages: |
271-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smart CE |
Year: |
2011 |
Journal: |
Oncogene |
Title: |
Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. |
Volume: |
30 |
Issue: |
13 |
Pages: |
1597-607 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blackshear PE |
Year: |
1998 |
Journal: |
Oncogene |
Title: |
Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice. |
Volume: |
16 |
Issue: |
1 |
Pages: |
61-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bennett LM |
Year: |
1995 |
Journal: |
Genomics |
Title: |
Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11. |
Volume: |
29 |
Issue: |
3 |
Pages: |
576-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Z |
Year: |
2020 |
Journal: |
Oncogene |
Title: |
Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA. |
Volume: |
39 |
Issue: |
47 |
Pages: |
7051-7062 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suberbielle E |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice. |
Volume: |
6 |
|
Pages: |
8897 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao C |
Year: |
2007 |
Journal: |
Cell |
Title: |
The XIST noncoding RNA functions independently of BRCA1 in X inactivation. |
Volume: |
128 |
Issue: |
5 |
Pages: |
977-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leung E |
Year: |
2023 |
Journal: |
Front Neurosci |
Title: |
BRCA1 heterozygosity promotes DNA damage-induced senescence in a sex-specific manner following repeated mild traumatic brain injury. |
Volume: |
17 |
|
Pages: |
1225226 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai L |
Year: |
2013 |
Journal: |
Exp Cell Res |
Title: |
Transgenic expression of BRCA1 disturbs hematopoietic stem and progenitor cells quiescence and function. |
Volume: |
319 |
Issue: |
17 |
Pages: |
2739-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rajan JV |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells. |
Volume: |
93 |
Issue: |
23 |
Pages: |
13078-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shukla PC |
Year: |
2011 |
Journal: |
Nat Commun |
Title: |
BRCA1 is an essential regulator of heart function and survival following myocardial infarction. |
Volume: |
2 |
|
Pages: |
593 |
|
•
•
•
•
•
|
Publication |
First Author: |
Molyneux G |
Year: |
2010 |
Journal: |
Cell Stem Cell |
Title: |
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. |
Volume: |
7 |
Issue: |
3 |
Pages: |
403-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bach K |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors. |
Volume: |
12 |
Issue: |
1 |
Pages: |
1502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai F |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development. |
Volume: |
74 |
Issue: |
21 |
Pages: |
6161-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao L |
Year: |
2003 |
Journal: |
Genes Dev |
Title: |
Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform. |
Volume: |
17 |
Issue: |
2 |
Pages: |
201-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nair SJ |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development. |
Volume: |
7 |
|
Pages: |
10913 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu X |
Year: |
2003 |
Journal: |
Development |
Title: |
Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice. |
Volume: |
130 |
Issue: |
9 |
Pages: |
2001-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun H |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing. |
Volume: |
11 |
Issue: |
20 |
Pages: |
9967-9987 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quinn BA |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53. |
Volume: |
4 |
Issue: |
12 |
Pages: |
e8404 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broering TJ |
Year: |
2014 |
Journal: |
J Cell Biol |
Title: |
BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis. |
Volume: |
205 |
Issue: |
5 |
Pages: |
663-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bidany-Mizrahi T |
Year: |
2024 |
Journal: |
Cell Death Discov |
Title: |
Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection. |
Volume: |
10 |
Issue: |
1 |
Pages: |
145 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong B |
Year: |
2008 |
Journal: |
Biol Reprod |
Title: |
BRCA1 is required for meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes. |
Volume: |
79 |
Issue: |
4 |
Pages: |
718-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kakarougkas A |
Year: |
2013 |
Journal: |
Nucleic Acids Res |
Title: |
Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection. |
Volume: |
41 |
Issue: |
22 |
Pages: |
10298-311 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang X |
Year: |
2024 |
Journal: |
BMC Biol |
Title: |
GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer. |
Volume: |
22 |
Issue: |
1 |
Pages: |
85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2000 |
Journal: |
DNA Cell Biol |
Title: |
VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells. |
Volume: |
19 |
Issue: |
5 |
Pages: |
253-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zabludoff SD |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
BRCA1 mRNA is expressed highly during meiosis and spermiogenesis but not during mitosis of male germ cells. |
Volume: |
13 |
Issue: |
3 |
Pages: |
649-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lane TF |
Year: |
2000 |
Journal: |
Oncogene |
Title: |
Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice. |
Volume: |
19 |
Issue: |
36 |
Pages: |
4085-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian F |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade. |
Volume: |
110 |
Issue: |
33 |
Pages: |
13558-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao L |
Year: |
2009 |
Journal: |
Mol Cell |
Title: |
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. |
Volume: |
35 |
Issue: |
4 |
Pages: |
534-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shakya R |
Year: |
2011 |
Journal: |
Science |
Title: |
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. |
Volume: |
334 |
Issue: |
6055 |
Pages: |
525-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tarpey MD |
Year: |
2019 |
Journal: |
J Physiol |
Title: |
Induced in vivo knockdown of the Brca1 gene in skeletal muscle results in skeletal muscle weakness. |
Volume: |
597 |
Issue: |
3 |
Pages: |
869-887 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin L |
Year: |
1998 |
Journal: |
Biochim Biophys Acta |
Title: |
cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus. |
Volume: |
1443 |
Issue: |
1-2 |
Pages: |
211-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hakem R |
Year: |
1997 |
Journal: |
Nat Genet |
Title: |
Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation. |
Volume: |
16 |
Issue: |
3 |
Pages: |
298-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasanuma H |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes. |
Volume: |
115 |
Issue: |
45 |
Pages: |
E10642-E10651 |
|
•
•
•
•
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Publication |
First Author: |
Chen J |
Year: |
2020 |
Journal: |
Cell Death Differ |
Title: |
53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice. |
Volume: |
27 |
Issue: |
9 |
Pages: |
2552-2567 |
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•
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•
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Publication |
First Author: |
Hakem R |
Year: |
1996 |
Journal: |
Cell |
Title: |
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. |
Volume: |
85 |
Issue: |
7 |
Pages: |
1009-23 |
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•
•
•
•
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Publication |
First Author: |
Chodankar R |
Year: |
2005 |
Journal: |
Curr Biol |
Title: |
Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells. |
Volume: |
15 |
Issue: |
6 |
Pages: |
561-5 |
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•
•
•
•
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Publication |
First Author: |
Mixon M |
Year: |
2000 |
Journal: |
Oncogene |
Title: |
Expression of Brca1 and splice variant Brca1delta11 RNA levels in mouse mammary gland during normal development and tumorigenesis. |
Volume: |
19 |
Issue: |
46 |
Pages: |
5237-43 |
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•
•
•
•
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Publication |
First Author: |
Xu X |
Year: |
2001 |
Journal: |
Nat Genet |
Title: |
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. |
Volume: |
28 |
Issue: |
3 |
Pages: |
266-71 |
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•
•
•
•
•
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Publication |
First Author: |
Shen SX |
Year: |
1998 |
Journal: |
Oncogene |
Title: |
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. |
Volume: |
17 |
Issue: |
24 |
Pages: |
3115-24 |
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•
•
•
•
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Publication |
First Author: |
Lane TF |
Year: |
1995 |
Journal: |
Genes Dev |
Title: |
Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. |
Volume: |
9 |
Issue: |
21 |
Pages: |
2712-22 |
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•
•
•
•
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Publication |
First Author: |
Cao L |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency. |
Volume: |
25 |
Issue: |
10 |
Pages: |
2167-77 |
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•
•
•
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Publication |
First Author: |
Schröck E |
Year: |
1996 |
Journal: |
Hum Genet |
Title: |
The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D. |
Volume: |
97 |
Issue: |
2 |
Pages: |
256-9 |
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•
•
•
•
•
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Publication |
First Author: |
Bai F |
Year: |
2022 |
Journal: |
Cell Death Dis |
Title: |
Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway. |
Volume: |
13 |
Issue: |
3 |
Pages: |
195 |
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•
•
•
•
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Publication |
First Author: |
Yen HY |
Year: |
2012 |
Journal: |
Lab Invest |
Title: |
Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs. |
Volume: |
92 |
Issue: |
6 |
Pages: |
802-11 |
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•
•
•
•
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Publication |
First Author: |
Bai F |
Year: |
2013 |
Journal: |
Oncogene |
Title: |
Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation. |
Volume: |
32 |
Issue: |
22 |
Pages: |
2715-25 |
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•
•
•
•
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Publication |
First Author: |
Whitehouse C |
Year: |
2004 |
Journal: |
Gene |
Title: |
Brca1 expression is regulated by a bidirectional promoter that is shared by the Nbr1 gene in mouse. |
Volume: |
326 |
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Pages: |
87-96 |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
580
 |
Fragment?: |
false |
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•
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Publication |
First Author: |
Wang X |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure. |
Volume: |
279 |
Issue: |
28 |
Pages: |
29606-14 |
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•
•
•
•
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Publication |
First Author: |
Marquis ST |
Year: |
1995 |
Journal: |
Nat Genet |
Title: |
The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. |
Volume: |
11 |
Issue: |
1 |
Pages: |
17-26 |
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•
•
•
•
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Publication |
First Author: |
Drake DM |
Year: |
2024 |
Journal: |
Redox Biol |
Title: |
BRCA1 protein dose-dependent risk for embryonic oxidative DNA damage, embryopathies and neurodevelopmental disorders with and without ethanol exposure. |
Volume: |
70 |
|
Pages: |
103070 |
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•
•
•
•
•
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Publication |
First Author: |
Bowen TJ |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching. |
Volume: |
65 |
Issue: |
19 |
Pages: |
8736-46 |
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•
•
•
•
•
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Publication |
First Author: |
Cao L |
Year: |
2007 |
Journal: |
Carcinogenesis |
Title: |
Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach. |
Volume: |
28 |
Issue: |
7 |
Pages: |
1401-7 |
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•
•
•
•
•
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Publication |
First Author: |
Clark-Knowles KV |
Year: |
2007 |
Journal: |
Exp Cell Res |
Title: |
Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes. |
Volume: |
313 |
Issue: |
1 |
Pages: |
133-45 |
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•
•
•
•
•
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Publication |
First Author: |
Tornillo G |
Year: |
2024 |
Journal: |
Dis Model Mech |
Title: |
Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model. |
Volume: |
17 |
Issue: |
1 |
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•
•
•
•
•
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Publication |
First Author: |
Kitami K |
Year: |
2018 |
Journal: |
PLoS Genet |
Title: |
BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development. |
Volume: |
14 |
Issue: |
5 |
Pages: |
e1007340 |
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•
•
•
•
•
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Publication |
First Author: |
Chen J |
Year: |
1998 |
Journal: |
Mol Cell |
Title: |
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. |
Volume: |
2 |
Issue: |
3 |
Pages: |
317-28 |
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•
•
•
•
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Publication |
First Author: |
Bennett LM |
Year: |
2000 |
Journal: |
Cancer Res |
Title: |
Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol. |
Volume: |
60 |
Issue: |
13 |
Pages: |
3461-9 |
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•
•
•
•
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Publication |
First Author: |
Upton DH |
Year: |
2015 |
Journal: |
Horm Cancer |
Title: |
Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors. |
Volume: |
6 |
Issue: |
4 |
Pages: |
142-52 |
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