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Search results 101 to 200 out of 2452 for Brca1

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Type Details Score
Publication
First Author: Wang L
Year: 2013
Journal: EMBO J
Title: BRCA1 is a negative modulator of the PRC2 complex.
Volume: 32
Issue: 11
Pages: 1584-97
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Khavari PA
Year: 1993
Journal: Nature
Title: BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription.
Volume: 366
Issue: 6451
Pages: 170-4
Protein
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: true
Publication
First Author: Yu X
Year: 2003
Journal: Science
Title: The BRCT domain is a phospho-protein binding domain.
Volume: 302
Issue: 5645
Pages: 639-42
Publication
First Author: Dong Y
Year: 2003
Journal: Mol Cell
Title: Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Volume: 12
Issue: 5
Pages: 1087-99
Publication
First Author: Miao K
Year: 2020
Journal: Nat Commun
Title: NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation.
Volume: 11
Issue: 1
Pages: 3256
Publication
First Author: Nacson J
Year: 2018
Journal: Cell Rep
Title: BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Volume: 24
Issue: 13
Pages: 3513-3527.e7
Publication
First Author: Gowen LC
Year: 1996
Journal: Nat Genet
Title: Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities.
Volume: 12
Issue: 2
Pages: 191-4
Publication
First Author: Vasanthakumar A
Year: 2016
Journal: Blood
Title: Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
Volume: 127
Issue: 3
Pages: 310-3
Publication
First Author: Deng CX
Year: 2001
Journal: Mutat Res
Title: Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice.
Volume: 477
Issue: 1-2
Pages: 183-9
Publication
First Author: Rao VN
Year: 1996
Journal: Oncogene
Title: Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts.
Volume: 12
Issue: 3
Pages: 523-8
Publication
First Author: Berton TR
Year: 2003
Journal: Oncogene
Title: Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.
Volume: 22
Issue: 35
Pages: 5415-26
Publication
First Author: Phillips KW
Year: 1997
Journal: Lab Invest
Title: Brca1 is expressed independently of hormonal stimulation in the mouse ovary.
Volume: 76
Issue: 3
Pages: 419-25
Publication
First Author: Moynahan ME
Year: 2002
Journal: Oncogene
Title: The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans.
Volume: 21
Issue: 58
Pages: 8994-9007
Publication
First Author: Wang H
Year: 2019
Journal: Cell
Title: Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.
Volume: 178
Issue: 1
Pages: 135-151.e19
Publication
First Author: McAllister KA
Year: 2002
Journal: Breast Cancer Res
Title: Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?
Volume: 4
Issue: 2
Pages: 54-7
Publication  
First Author: Deng CX
Year: 2003
Journal: Hum Mol Genet
Title: Roles of BRCA1 in DNA damage repair: a link between development and cancer.
Volume: 12 Spec No 1
Pages: R113-23
Publication
First Author: Chen KS
Year: 1996
Journal: Carcinogenesis
Title: Cloning, genetic mapping and expression studies of the rat Brca1 gene.
Volume: 17
Issue: 8
Pages: 1561-6
Publication
First Author: Arlt MF
Year: 2004
Journal: Mol Cell Biol
Title: BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function.
Volume: 24
Issue: 15
Pages: 6701-9
Publication
First Author: Bennett LM
Year: 1999
Journal: Mamm Genome
Title: Sequence analysis of the rat Brca1 homolog and its promoter region.
Volume: 10
Issue: 1
Pages: 19-25
Publication
First Author: Jackson KC
Year: 2014
Journal: J Lipid Res
Title: BRCA1 is a novel regulator of metabolic function in skeletal muscle.
Volume: 55
Issue: 4
Pages: 668-80
Publication
First Author: Lowndes NF
Year: 2010
Journal: DNA Repair (Amst)
Title: The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer.
Volume: 9
Issue: 10
Pages: 1112-6
Publication
First Author: DeGregorio L
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the Brca1 gene on mouse chromosome 11.
Volume: 7
Issue: 3
Pages: 242
Publication
First Author: Bachelier R
Year: 2005
Journal: Oncol Rep
Title: Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice.
Volume: 14
Issue: 5
Pages: 1117-20
Publication
First Author: Bachelier R
Year: 2003
Journal: Oncogene
Title: Normal lymphocyte development and thymic lymphoma formation in Brca1 exon-11-deficient mice.
Volume: 22
Issue: 4
Pages: 528-37
Publication
First Author: Gorrini C
Year: 2013
Journal: J Exp Med
Title: BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival.
Volume: 210
Issue: 8
Pages: 1529-44
Publication
First Author: Brodie SG
Year: 2001
Journal: Oncogene
Title: Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice.
Volume: 20
Issue: 51
Pages: 7514-23
Publication
First Author: Chiang HC
Year: 2018
Journal: Sci Rep
Title: Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development.
Volume: 8
Issue: 1
Pages: 2731
Publication  
First Author: Drake DM
Year: 2021
Journal: Redox Biol
Title: Novel mechanisms in alcohol neurodevelopmental disorders via BRCA1 depletion and BRCA1-dependent NADPH oxidase regulation.
Volume: 48
Pages: 102148
Publication
First Author: Deng CX
Year: 2000
Journal: Oncogene
Title: Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.
Volume: 19
Issue: 8
Pages: 1059-64
Publication
First Author: Pageau GJ
Year: 2006
Journal: J Cell Biol
Title: BRCA1 foci in normal S-phase nuclei are linked to interphase centromeres and replication of pericentric heterochromatin.
Volume: 175
Issue: 5
Pages: 693-701
Protein
Organism: Mus musculus/domesticus
Length: 1811  
Fragment?: false
Publication
First Author: Bunting SF
Year: 2012
Journal: Mol Cell
Title: BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Volume: 46
Issue: 2
Pages: 125-35
Publication
First Author: Xu X
Year: 1999
Journal: Nat Genet
Title: Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
Volume: 22
Issue: 1
Pages: 37-43
Publication
First Author: Drost R
Year: 2011
Journal: Cancer Cell
Title: BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.
Volume: 20
Issue: 6
Pages: 797-809
Publication
First Author: Bernard-Gallon DJ
Year: 2001
Journal: Int J Oncol
Title: Brca1 and Brca2 protein expression patterns in different tissues of murine origin.
Volume: 18
Issue: 2
Pages: 271-80
Publication
First Author: Smart CE
Year: 2011
Journal: Oncogene
Title: Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.
Volume: 30
Issue: 13
Pages: 1597-607
Publication
First Author: Blackshear PE
Year: 1998
Journal: Oncogene
Title: Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice.
Volume: 16
Issue: 1
Pages: 61-8
Publication
First Author: Bennett LM
Year: 1995
Journal: Genomics
Title: Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11.
Volume: 29
Issue: 3
Pages: 576-81
Publication
First Author: Xu Z
Year: 2020
Journal: Oncogene
Title: Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.
Volume: 39
Issue: 47
Pages: 7051-7062
Publication  
First Author: Suberbielle E
Year: 2015
Journal: Nat Commun
Title: DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.
Volume: 6
Pages: 8897
Publication
First Author: Xiao C
Year: 2007
Journal: Cell
Title: The XIST noncoding RNA functions independently of BRCA1 in X inactivation.
Volume: 128
Issue: 5
Pages: 977-89
Publication  
First Author: Leung E
Year: 2023
Journal: Front Neurosci
Title: BRCA1 heterozygosity promotes DNA damage-induced senescence in a sex-specific manner following repeated mild traumatic brain injury.
Volume: 17
Pages: 1225226
Publication
First Author: Bai L
Year: 2013
Journal: Exp Cell Res
Title: Transgenic expression of BRCA1 disturbs hematopoietic stem and progenitor cells quiescence and function.
Volume: 319
Issue: 17
Pages: 2739-46
Publication
First Author: Rajan JV
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells.
Volume: 93
Issue: 23
Pages: 13078-83
Publication  
First Author: Shukla PC
Year: 2011
Journal: Nat Commun
Title: BRCA1 is an essential regulator of heart function and survival following myocardial infarction.
Volume: 2
Pages: 593
Publication
First Author: Molyneux G
Year: 2010
Journal: Cell Stem Cell
Title: BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells.
Volume: 7
Issue: 3
Pages: 403-17
Publication
First Author: Bach K
Year: 2021
Journal: Nat Commun
Title: Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors.
Volume: 12
Issue: 1
Pages: 1502
Publication
First Author: Bai F
Year: 2014
Journal: Cancer Res
Title: BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development.
Volume: 74
Issue: 21
Pages: 6161-72
Publication
First Author: Cao L
Year: 2003
Journal: Genes Dev
Title: Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform.
Volume: 17
Issue: 2
Pages: 201-13
Publication  
First Author: Nair SJ
Year: 2016
Journal: Nat Commun
Title: Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development.
Volume: 7
Pages: 10913
Publication
First Author: Xu X
Year: 2003
Journal: Development
Title: Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice.
Volume: 130
Issue: 9
Pages: 2001-12
Publication
First Author: Sun H
Year: 2021
Journal: Theranostics
Title: Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.
Volume: 11
Issue: 20
Pages: 9967-9987
Publication
First Author: Quinn BA
Year: 2009
Journal: PLoS One
Title: Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.
Volume: 4
Issue: 12
Pages: e8404
Publication
First Author: Broering TJ
Year: 2014
Journal: J Cell Biol
Title: BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis.
Volume: 205
Issue: 5
Pages: 663-75
Publication
First Author: Bidany-Mizrahi T
Year: 2024
Journal: Cell Death Discov
Title: Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection.
Volume: 10
Issue: 1
Pages: 145
Publication
First Author: Xiong B
Year: 2008
Journal: Biol Reprod
Title: BRCA1 is required for meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes.
Volume: 79
Issue: 4
Pages: 718-26
Publication
First Author: Kakarougkas A
Year: 2013
Journal: Nucleic Acids Res
Title: Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection.
Volume: 41
Issue: 22
Pages: 10298-311
Publication
First Author: Wang X
Year: 2024
Journal: BMC Biol
Title: GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer.
Volume: 22
Issue: 1
Pages: 85
Publication
First Author: Zhang H
Year: 2000
Journal: DNA Cell Biol
Title: VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells.
Volume: 19
Issue: 5
Pages: 253-63
Publication
First Author: Zabludoff SD
Year: 1996
Journal: Oncogene
Title: BRCA1 mRNA is expressed highly during meiosis and spermiogenesis but not during mitosis of male germ cells.
Volume: 13
Issue: 3
Pages: 649-53
Publication
First Author: Lane TF
Year: 2000
Journal: Oncogene
Title: Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice.
Volume: 19
Issue: 36
Pages: 4085-90
Publication
First Author: Tian F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.
Volume: 110
Issue: 33
Pages: 13558-63
Publication
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
Publication
First Author: Shakya R
Year: 2011
Journal: Science
Title: BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Volume: 334
Issue: 6055
Pages: 525-8
Publication
First Author: Tarpey MD
Year: 2019
Journal: J Physiol
Title: Induced in vivo knockdown of the Brca1 gene in skeletal muscle results in skeletal muscle weakness.
Volume: 597
Issue: 3
Pages: 869-887
Publication
First Author: Lin L
Year: 1998
Journal: Biochim Biophys Acta
Title: cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus.
Volume: 1443
Issue: 1-2
Pages: 211-6
Publication
First Author: Hakem R
Year: 1997
Journal: Nat Genet
Title: Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.
Volume: 16
Issue: 3
Pages: 298-302
Publication
First Author: Sasanuma H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
Volume: 115
Issue: 45
Pages: E10642-E10651
Publication
First Author: Chen J
Year: 2020
Journal: Cell Death Differ
Title: 53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice.
Volume: 27
Issue: 9
Pages: 2552-2567
Publication
First Author: Hakem R
Year: 1996
Journal: Cell
Title: The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.
Volume: 85
Issue: 7
Pages: 1009-23
Publication
First Author: Chodankar R
Year: 2005
Journal: Curr Biol
Title: Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells.
Volume: 15
Issue: 6
Pages: 561-5
Publication
First Author: Mixon M
Year: 2000
Journal: Oncogene
Title: Expression of Brca1 and splice variant Brca1delta11 RNA levels in mouse mammary gland during normal development and tumorigenesis.
Volume: 19
Issue: 46
Pages: 5237-43
Publication
First Author: Xu X
Year: 2001
Journal: Nat Genet
Title: Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.
Volume: 28
Issue: 3
Pages: 266-71
Publication
First Author: Shen SX
Year: 1998
Journal: Oncogene
Title: A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.
Volume: 17
Issue: 24
Pages: 3115-24
Publication
First Author: Lane TF
Year: 1995
Journal: Genes Dev
Title: Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice.
Volume: 9
Issue: 21
Pages: 2712-22
Publication
First Author: Cao L
Year: 2006
Journal: EMBO J
Title: ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Volume: 25
Issue: 10
Pages: 2167-77
Publication
First Author: Schröck E
Year: 1996
Journal: Hum Genet
Title: The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.
Volume: 97
Issue: 2
Pages: 256-9
Publication
First Author: Bai F
Year: 2022
Journal: Cell Death Dis
Title: Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway.
Volume: 13
Issue: 3
Pages: 195
Publication
First Author: Yen HY
Year: 2012
Journal: Lab Invest
Title: Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.
Volume: 92
Issue: 6
Pages: 802-11
Publication
First Author: Bai F
Year: 2013
Journal: Oncogene
Title: Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation.
Volume: 32
Issue: 22
Pages: 2715-25
Publication  
First Author: Whitehouse C
Year: 2004
Journal: Gene
Title: Brca1 expression is regulated by a bidirectional promoter that is shared by the Nbr1 gene in mouse.
Volume: 326
Pages: 87-96
Protein
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
Publication
First Author: Wang X
Year: 2004
Journal: J Biol Chem
Title: Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.
Volume: 279
Issue: 28
Pages: 29606-14
Publication
First Author: Marquis ST
Year: 1995
Journal: Nat Genet
Title: The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.
Volume: 11
Issue: 1
Pages: 17-26
Publication  
First Author: Drake DM
Year: 2024
Journal: Redox Biol
Title: BRCA1 protein dose-dependent risk for embryonic oxidative DNA damage, embryopathies and neurodevelopmental disorders with and without ethanol exposure.
Volume: 70
Pages: 103070
Publication
First Author: Bowen TJ
Year: 2005
Journal: Cancer Res
Title: Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching.
Volume: 65
Issue: 19
Pages: 8736-46
Publication
First Author: Cao L
Year: 2007
Journal: Carcinogenesis
Title: Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach.
Volume: 28
Issue: 7
Pages: 1401-7
Publication
First Author: Clark-Knowles KV
Year: 2007
Journal: Exp Cell Res
Title: Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.
Volume: 313
Issue: 1
Pages: 133-45
Publication  
First Author: Tornillo G
Year: 2024
Journal: Dis Model Mech
Title: Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model.
Volume: 17
Issue: 1
Publication
First Author: Kitami K
Year: 2018
Journal: PLoS Genet
Title: BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development.
Volume: 14
Issue: 5
Pages: e1007340
Publication
First Author: Chen J
Year: 1998
Journal: Mol Cell
Title: Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
Volume: 2
Issue: 3
Pages: 317-28
Publication
First Author: Bennett LM
Year: 2000
Journal: Cancer Res
Title: Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol.
Volume: 60
Issue: 13
Pages: 3461-9
Publication
First Author: Upton DH
Year: 2015
Journal: Horm Cancer
Title: Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors.
Volume: 6
Issue: 4
Pages: 142-52