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Search results 101 to 125 out of 125 for Cand1

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Type Details Score
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
12504026 | -
First Author: Zheng J
Year: 2002
Journal: Mol Cell
Title: CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.
Volume: 10
Issue: 6
Pages: 1519-26
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Publication
23453757 | -
First Author: Pierce NW
Year: 2013
Journal: Cell
Title: Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins.
Volume: 153
Issue: 1
Pages: 206-15
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Protein
Q6ZQ38
Organism: Mus musculus/domesticus
Length: 1230  
Fragment?: false
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Allele
Tg(Myh6-Cand1)1Zpan | MGI:7614263
Name: transgene insertion 1, Zhenwei Pan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Cand1<em3(CAG-Cand1)Zpan> | MGI:7750861
Name: cullin associated and neddylation disassociated 1; endonuclease-mediated mutation 3, Zhenwei Pan
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Myh6-Cand1)1Zpan/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
12504025 | -
First Author: Liu J
Year: 2002
Journal: Mol Cell
Title: NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.
Volume: 10
Issue: 6
Pages: 1511-8
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Publication
12609982 | -
First Author: Min KW
Year: 2003
Journal: J Biol Chem
Title: TIP120A associates with cullins and modulates ubiquitin ligase activity.
Volume: 278
Issue: 18
Pages: 15905-10
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Publication
16449638 | -
First Author: Lo SC
Year: 2006
Journal: Mol Cell Biol
Title: CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
Volume: 26
Issue: 4
Pages: 1235-44
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Protein Domain
IPR039852 | CAND1/CAND2
Type: Family
Description: This entry includes cullin-associated NEDD8-dissociated proteins 1 (CAND1 also known as TIP120A) and 2 (CAND2); these proteins have a C-terminal TATA-binding protein interacting (TIP20) domain. CAND1 is required for the assembly of the SCF E3 ubiquitin ligase complex. The SCF ubiquitin E3 ligase consists of SKP1, CUL1 and F-box protein, and it regulates ubiquitin-dependent proteolysis. CAND1 binds to CUL1, preventing it from associating with the other components that form the ligase. Neddylation of CUL1 (or the presence of SKP1 and ATP) dissociates it from CAND1, allowing the ligase complex to form [, , ]. CAND1 also interacts with CUL3, a component of the Cul3-dependent E3 ubiquitin ligase complex []. CAND1 has been proposed to be an F-box protein exchange factor, and as substrates of the ligase complex are degraded by the proteasome and depleted, the ligase complex enters an intermediate, deneddylated state when CAND1 can bind, promoting dissociation of the substrate-recognition subunit and recruitment of a new substrate-recognition subunit []. CAND2 is uncharacterized but is assumed to have similar roles to CAND1.
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Protein
Q9CSM7
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: false
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Protein
Q6ZQ73
Organism: Mus musculus/domesticus
Length: 1235  
Fragment?: false
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Protein
Q3UM57
Organism: Mus musculus/domesticus
Length: 1235  
Fragment?: false
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Protein
Q3TD19
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: true
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Protein
D3YWC5
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
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Protein
Q3UMI9
Organism: Mus musculus/domesticus
Length: 700  
Fragment?: true
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