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Search results 101 to 200 out of 1022 for Casp1

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Type Details Score
Publication
28126413 | J:239600
 
First Author: Jessop F
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome activity.
Volume: 318
Pages: 58-68
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Publication
19179418 | J:147167
First Author: Breitbach K
Year: 2009
Journal: Infect Immun
Title: Caspase-1 mediates resistance in murine melioidosis.
Volume: 77
Issue: 4
Pages: 1589-95
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Publication
19487481 | J:151327
First Author: Liu N
Year: 2009
Journal: Infect Immun
Title: The caspase 1 inflammasome is not required for control of murine Lyme borreliosis.
Volume: 77
Issue: 8
Pages: 3320-7
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Publication
25017793 | J:218491
First Author: Gao P
Year: 2014
Journal: Biochim Biophys Acta
Title: Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathy.
Volume: 1843
Issue: 11
Pages: 2448-60
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Publication
21804020 | J:177980
First Author: Bergsbaken T
Year: 2011
Journal: J Immunol
Title: Coordinated host responses during pyroptosis: caspase-1-dependent lysosome exocytosis and inflammatory cytokine maturation.
Volume: 187
Issue: 5
Pages: 2748-54
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Publication
14734619 | J:88971
First Author: Tsuji NM
Year: 2004
Journal: Int Immunol
Title: Roles of caspase-1 in Listeria infection in mice.
Volume: 16
Issue: 2
Pages: 335-43
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Publication
8999548 | J:298991
First Author: Gu Y
Year: 1997
Journal: Science
Title: Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme.
Volume: 275
Issue: 5297
Pages: 206-9
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Publication
38672517 | J:347674
 
First Author: Wang Y
Year: 2024
Journal: Biomolecules
Title: Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism.
Volume: 14
Issue: 4
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Publication
34734155 | J:341007
 
First Author: Devant P
Year: 2021
Journal: Sci Immunol
Title: Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β converting enzyme.
Volume: 6
Issue: 62
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Publication
10353249 | J:55036
First Author: Ona VO
Year: 1999
Journal: Nature
Title: Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease.
Volume: 399
Issue: 6733
Pages: 263-7
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Publication
25127135 | J:297265
First Author: Liu T
Year: 2014
Journal: Cell Rep
Title: Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response.
Volume: 8
Issue: 4
Pages: 974-82
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Publication
32613271 | J:309363
First Author: Barber G
Year: 2020
Journal: Cancer Immunol Immunother
Title: Characterizing caspase-1 involvement during esophageal disease progression.
Volume: 69
Issue: 12
Pages: 2635-2649
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Publication
36930645 | J:346042
First Author: Devi S
Year: 2023
Journal: Cell Rep
Title: CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout.
Volume: 42
Issue: 3
Pages: 112265
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Publication
8670890 | J:113677
First Author: Chen Y
Year: 1996
Journal: EMBO J
Title: A bacterial invasin induces macrophage apoptosis by binding directly to ICE.
Volume: 15
Issue: 15
Pages: 3853-60
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Publication
8242740 | J:39908
First Author: Yuan J
Year: 1993
Journal: Cell
Title: The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme.
Volume: 75
Issue: 4
Pages: 641-52
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Publication
8242741 | J:15702
First Author: Miura M
Year: 1993
Journal: Cell
Title: Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3.
Volume: 75
Issue: 4
Pages: 653-60
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Publication
7822802 | J:23022
First Author: Miller BE
Year: 1995
Journal: J Immunol
Title: Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme.
Volume: 154
Issue: 3
Pages: 1331-8
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Publication
7498492 | J:29963
First Author: Kumar S
Year: 1995
Journal: FEBS Lett
Title: Role of multiple cellular proteases in the execution of programmed cell death.
Volume: 375
Issue: 3
Pages: 169-73
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Publication
9047242 | J:38709
First Author: Sarin A
Year: 1997
Journal: Immunity
Title: Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.
Volume: 6
Issue: 2
Pages: 209-15
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Publication
9427519 | J:46717
First Author: Yao J
Year: 1997
Journal: Brain Res Mol Brain Res
Title: Induction of interleukin-1 beta-converting enzyme (ICE) in murine microglia by lipopolysaccharide.
Volume: 51
Issue: 1-2
Pages: 170-8
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Publication
10069384 | J:53244
First Author: van Molle W
Year: 1999
Journal: FEBS Lett
Title: Caspase-1 is not involved in experimental hepatitis in mouse.
Volume: 445
Issue: 1
Pages: 115-8
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Publication
15157512 | J:36552
First Author: Whyte M
Year: 1996
Journal: Trends Cell Biol
Title: A link between cell-surface receptors and ICE proteases.
Volume: 6
Issue: 11
Pages: 418
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Publication
16301671 | J:122153
First Author: Kahlenberg JM
Year: 2005
Journal: J Immunol
Title: Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis.
Volume: 175
Issue: 11
Pages: 7611-22
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Publication
17600714 | J:124166
First Author: Feldmeyer L
Year: 2007
Journal: Curr Biol
Title: The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes.
Volume: 17
Issue: 13
Pages: 1140-5
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Publication
17303764 | J:133697
First Author: Merkle S
Year: 2007
Journal: Circ Res
Title: A role for caspase-1 in heart failure.
Volume: 100
Issue: 5
Pages: 645-53
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Publication
17599095 | J:141355
First Author: Fernandes-Alnemri T
Year: 2007
Journal: Cell Death Differ
Title: The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation.
Volume: 14
Issue: 9
Pages: 1590-604
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Publication
19001420 | J:145568
First Author: Timmer AM
Year: 2009
Journal: J Biol Chem
Title: Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis.
Volume: 284
Issue: 2
Pages: 862-71
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Publication
24481253 | J:206725
First Author: Bulau AM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Volume: 111
Issue: 7
Pages: 2650-5
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Publication
25313054 | J:216573
First Author: Yu J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy.
Volume: 111
Issue: 43
Pages: 15514-9
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Publication
25705884 | J:221900
First Author: Rothmeier AS
Year: 2015
Journal: J Clin Invest
Title: Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles.
Volume: 125
Issue: 4
Pages: 1471-84
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Publication
29432122 | J:263055
First Author: Boucher D
Year: 2018
Journal: J Exp Med
Title: Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Volume: 215
Issue: 3
Pages: 827-840
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Publication
29866702 | J:264068
First Author: Monteith AJ
Year: 2018
Journal: J Immunol
Title: mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a.
Volume: 201
Issue: 2
Pages: 371-382
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Publication
31108171 | J:295521
 
First Author: Towers AE
Year: 2019
Journal: Brain Behav Immun
Title: Handling stress impairs learning through a mechanism involving caspase-1 activation and adenosine signaling.
Volume: 80
Pages: 763-776
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Publication
34502478 | J:310899
 
First Author: Ramesova A
Year: 2021
Journal: Int J Mol Sci
Title: Caspase-1 Inhibition Impacts the Formation of Chondrogenic Nodules, and the Expression of Markers Related to Osteogenic Differentiation and Lipid Metabolism.
Volume: 22
Issue: 17
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Publication
35797768 | J:332328
 
First Author: Luo Y
Year: 2022
Journal: EBioMedicine
Title: Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
Volume: 82
Pages: 104087
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GXD Expression
GXD Expression
     
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:1329454
Age: embryonic day 4.0
Specimen Label: caspase-1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2668229
Assay Type: RT-PCR
Annotation Date: 2003-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:2668236
Age: embryonic day 12.0
Specimen Label: E12
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2668229
Assay Type: RT-PCR
Annotation Date: 2003-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:2668236
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2668229
Assay Type: RT-PCR
Annotation Date: 2003-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:2668236
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3664042
Assay Type: RNase protection
Annotation Date: 2006-10-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691018
Stage: TS18
Assay Id: MGI:3664058
Age: embryonic day 11.0
Image: 1
Specimen Label: E11
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3664042
Assay Type: RNase protection
Annotation Date: 2006-10-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691021
Stage: TS21
Assay Id: MGI:3664058
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3664042
Assay Type: RNase protection
Annotation Date: 2006-10-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691023
Stage: TS23
Assay Id: MGI:3664058
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3664042
Assay Type: RNase protection
Annotation Date: 2006-10-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691025
Stage: TS25
Assay Id: MGI:3664058
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3664042
Assay Type: RNase protection
Annotation Date: 2006-10-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1691027
Stage: TS27
Assay Id: MGI:3664058
Age: postnatal day 1
Image: 1
Specimen Label: P1
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6196370
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196561
Age: embryonic day 10.5
Specimen Label: Wt 1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6196370
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196561
Age: embryonic day 10.5
Specimen Label: Wt 2
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6196370
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196561
Age: embryonic day 10.5
Specimen Label: DKO 1
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6196370
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196561
Age: embryonic day 10.5
Specimen Label: DKO 2
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6196370
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196561
Age: embryonic day 10.5
Specimen Label: TKO 1
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6196370
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196561
Age: embryonic day 10.5
Specimen Label: TKO 2
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3027395
Assay Type: RT-PCR
Annotation Date: 2004-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1913726
Stage: TS26
Assay Id: MGI:3027398
Age: embryonic day 19.0
Specimen Label: COL2A1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3027395
Assay Type: RT-PCR
Annotation Date: 2004-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1913726
Stage: TS26
Assay Id: MGI:3027398
Age: embryonic day 19.0
Specimen Label: COL2A1 -/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3027395
Assay Type: RT-PCR
Annotation Date: 2004-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1913726
Stage: TS26
Assay Id: MGI:3027398
Age: embryonic day 19.0
Specimen Label: COL2A1 -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7469463
Assay Type: RT-PCR
Annotation Date: 2023-05-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3283426
Stage: TS26
Assay Id: MGI:7469481
Age: embryonic day 18.5
Image: 1
Specimen Label: WT
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7469463
Assay Type: RT-PCR
Annotation Date: 2023-05-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3283426
Stage: TS26
Assay Id: MGI:7469481
Age: embryonic day 18.5
Image: 1
Specimen Label: Spata2<-/->
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7469463
Assay Type: RT-PCR
Annotation Date: 2023-05-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3283426
Stage: TS26
Assay Id: MGI:7469481
Age: embryonic day 18.5
Image: 1
Specimen Label: Cyld<-/->
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469463
Assay Type: RT-PCR
Annotation Date: 2023-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283426
Stage: TS26
Assay Id: MGI:7469481
Age: embryonic day 18.5
Image: 1
Specimen Label: Cyld<-/->Spata2<-/->
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 2024-03-18
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:7612339
Age: postnatal adult
Specimen Label: O
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 2024-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:7612339
Age: embryonic day 0.5
Specimen Label: 1c
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 2024-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:7612339
Age: embryonic day 1.0
Specimen Label: 2c
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 2024-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:7612339
Age: embryonic day 2.0
Specimen Label: 8c
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1329385
Assay Type: RT-PCR
Annotation Date: 2024-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:7612339
Age: embryonic day 3.5
Specimen Label: B
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7444318
Age: embryonic day 15.0
Image: 1B
Note: Expression is in resting zones of the growth plate.
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7444318
Age: embryonic day 15.0
Image: 1C
Note: Expression is in proliferating zones of the growth plate.
Specimen Label: 1C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7444318
Age: embryonic day 15.0
Image: 1D
Note: Expression is in hypertrophic zones of the growth plate.
Specimen Label: 1D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7444318
Age: embryonic day 15.0
Image: 1E
Note: Expression is in chondroclasts and osteoclasts penetrating to the primary ossification center. Expression is absent in the zone of calcifying cartilage.
Specimen Label: 1E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7444318
Age: embryonic day 18.0
Image: 1F
Note: Expression is in resting and proliferating zones of the growth plate.
Specimen Label: 1F
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3262626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7444318
Age: embryonic day 18.0
Image: 1G
Note: Expression is in hypertrophic and ossification zones of the growth plate.
Specimen Label: 1G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7444318
Age: embryonic day 18.0
Image: 1H
Note: Expression is in osteoclasts of the ossification zones
Specimen Label: 1H
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7444123
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7444318
Age: embryonic day 12.0
Image: 1A
Note: Expression is in the bcondensed mesenchyme of the future growth plate.
Specimen Label: 1A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7428897
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7428907
Age: embryonic day 17.5
Note: Expression restricted to macrophages.
Specimen Label: 6C (left) E17 ctrl
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7428897
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7428907
Age: embryonic day 17.5
Note: Expression restricted to macrophages.
Specimen Label: 6C (left) E17 Twist2-IKK
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7428897
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7428907
Age: postnatal adult
Note: Expression restricted to macrophages.
Specimen Label: 6C (left) Adult ctrl
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7428897
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7428907
Age: postnatal adult
Note: Expression restricted to macrophages.
Specimen Label: 6C (left)) Adult Twist2-IKK
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
23567559 | J:205029
First Author: Ru H
Year: 2013
Journal: Cell Res
Title: Structural basis for termination of AIM2-mediated signaling by p202.
Volume: 23
Issue: 6
Pages: 855-8
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•
•
•
•
Publication
32122970 | J:286834
First Author: Douglas T
Year: 2020
Journal: J Biol Chem
Title: Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation.
Volume: 295
Issue: 16
Pages: 5216-5228
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Publication
29653983 | J:325839
First Author: Zeng Q
Year: 2018
Journal: Cancer Immunol Res
Title: Caspase-1 from Human Myeloid-Derived Suppressor Cells Can Promote T Cell-Independent Tumor Proliferation.
Volume: 6
Issue: 5
Pages: 566-577
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Publication
10890909 | J:63405
First Author: Wong ML
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis.
Volume: 97
Issue: 15
Pages: 8681-6
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•
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•
Publication
32346861 | J:350633
First Author: Tang Y
Year: 2020
Journal: Br J Pharmacol
Title: Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility.
Volume: 177
Issue: 15
Pages: 3519-3534
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•
•
•
Publication
11376856 | J:69589
First Author: Xu H
Year: 2001
Journal: Brain Res Mol Brain Res
Title: Attenuation of hypoxia-ischemia-induced monocyte chemoattractant protein-1 expression in brain of neonatal mice deficient in interleukin-1 converting enzyme.
Volume: 90
Issue: 1
Pages: 57-67
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•
•
•
•
Publication
24850431 | J:296300
First Author: Demon D
Year: 2014
Journal: Mucosal Immunol
Title: Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis.
Volume: 7
Issue: 6
Pages: 1480-91
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•
•
•
Publication
30089254 | J:271305
First Author: Monteleone M
Year: 2018
Journal: Cell Rep
Title: Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.
Volume: 24
Issue: 6
Pages: 1425-1433
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•
•
•
•
Publication
28345580 | J:263294
 
First Author: Man SM
Year: 2017
Journal: Sci Rep
Title: Differential roles of caspase-1 and caspase-11 in infection and inflammation.
Volume: 7
Pages: 45126
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•
•
•
•
Publication
32641037 | J:292497
First Author: Sachdev U
Year: 2020
Journal: Mol Med
Title: Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine.
Volume: 26
Issue: 1
Pages: 69
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•
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Publication
22658523 | J:187307
First Author: Akhter A
Year: 2012
Journal: Immunity
Title: Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Volume: 37
Issue: 1
Pages: 35-47
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Publication
30254377 | J:267627
First Author: Flores J
Year: 2018
Journal: Nat Commun
Title: Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model.
Volume: 9
Issue: 1
Pages: 3916
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Publication
9315289 | J:47538
First Author: Samokhvalov I
Year: 1997
Journal: Biochem Mol Biol Int
Title: Mice lacking a functional chk gene have no apparent defects in the hematopoietic system.
Volume: 43
Issue: 1
Pages: 115-22
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•
•
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•
Publication
34353890 | J:313327
 
First Author: Kim E
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of elastase enhances the adjuvanticity of alum and promotes anti-SARS-CoV-2 systemic and mucosal immunity.
Volume: 118
Issue: 34
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•
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•
Publication
28614717 | J:251828
First Author: Błażejewski AJ
Year: 2017
Journal: Cell Rep
Title: Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation.
Volume: 19
Issue: 11
Pages: 2319-2330
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•
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Publication
28990935 | J:252593
First Author: Cheng KT
Year: 2017
Journal: J Clin Invest
Title: Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.
Volume: 127
Issue: 11
Pages: 4124-4135
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•
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Publication
32350463 | J:293308
First Author: Lammert CR
Year: 2020
Journal: Nature
Title: AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment.
Volume: 580
Issue: 7805
Pages: 647-652
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•
Publication
7798197 | J:21880
First Author: Darmon AJ
Year: 1994
Journal: J Biol Chem
Title: The cytotoxic T cell proteinase granzyme B does not activate interleukin-1 beta-converting enzyme.
Volume: 269
Issue: 51
Pages: 32043-6
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•
•
•
Publication
8565829 | J:30827
First Author: Lund LR
Year: 1996
Journal: Development
Title: Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.
Volume: 122
Issue: 1
Pages: 181-93
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Publication
25452302 | J:224304
First Author: Segovia JA
Year: 2015
Journal: Mol Cell Biol
Title: Nedd8 regulates inflammasome-dependent caspase-1 activation.
Volume: 35
Issue: 3
Pages: 582-97
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Publication
29414788 | J:264197
First Author: Ramirez MLG
Year: 2018
Journal: J Biol Chem
Title: Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1.
Volume: 293
Issue: 18
Pages: 7058-7067
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Publication
30571969 | J:294379
First Author: Aira LE
Year: 2019
Journal: J Invest Dermatol
Title: Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice.
Volume: 139
Issue: 6
Pages: 1306-1317
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Publication
31998283 | J:297750
 
First Author: de Sant'Ana LP
Year: 2019
Journal: Front Immunol
Title: Absence of the Caspases 1/11 Modulates Liver Global Lipid Profile and Gut Microbiota in High-Fat-Diet-Induced Obese Mice.
Volume: 10
Pages: 2926
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Publication
27108091 | J:318416
 
First Author: Hughes CS
Year: 2016
Journal: Part Fibre Toxicol
Title: Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages.
Volume: 13
Pages: 19
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Publication
8446594 | J:17952
First Author: Molineaux SM
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Interleukin 1 beta (IL-1 beta) processing in murine macrophages requires a structurally conserved homologue of human IL-1 beta converting enzyme.
Volume: 90
Issue: 5
Pages: 1809-13
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Publication
19465481 | J:152429
First Author: Talabot-Ayer D
Year: 2009
Journal: J Biol Chem
Title: Interleukin-33 is biologically active independently of caspase-1 cleavage.
Volume: 284
Issue: 29
Pages: 19420-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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