| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoque M |
| Year: |
2024 |
| Journal: |
J Cell Biol |
| Title: |
The Cby3/ciBAR1 complex positions the annulus along the sperm flagellum during spermiogenesis. |
| Volume: |
223 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
chibby family member 1, beta catenin antagonist; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 1; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 2; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 2; targeted mutation 1, Velocigene |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2019 |
| Journal: |
J Cell Biol |
| Title: |
FAM92A1 is a BAR domain protein required for mitochondrial ultrastructure and function. |
| Volume: |
218 |
| Issue: |
1 |
| Pages: |
97-111 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6157654 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Sample 1 WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6157654 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Sample 1 Foxj1-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6157654 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Sample 2 WT |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672826 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6157654 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Sample 2 Foxj1-/- |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603911 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:6157775 |
| Age: |
embryonic day 7.5-8.0 |
|
|
| Specimen Label: |
Noto heterozygous |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603912 |
|
| Stage: |
TS12 |
| Assay Id: |
MGI:6157775 |
| Age: |
embryonic day 7.5-8.0 |
|
|
| Specimen Label: |
Noto heterozygous |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603911 |
|
| Stage: |
TS11 |
| Assay Id: |
MGI:6157775 |
| Age: |
embryonic day 7.5-8.0 |
|
|
| Specimen Label: |
Noto homozygous |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6156780 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-05-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603912 |
|
| Stage: |
TS12 |
| Assay Id: |
MGI:6157775 |
| Age: |
embryonic day 7.5-8.0 |
|
|
| Specimen Label: |
Noto homozygous |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3594419 |
| Pattern: |
Widespread |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3594419 |
| Pattern: |
Widespread |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
2D |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Areas of expression include the progress zone. |
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270519 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Areas of expression include the progress zone. |
| Specimen Label: |
2D |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274419 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274419 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Strong localization is seen at the cilia level. |
| Specimen Label: |
2E |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6376463 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274419 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:6376464 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
2D |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 1; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 2; targeted mutation 1e, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 2; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 1; targeted mutation 1b, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 1; endonuclease-mediated mutation 30, GemPharmatech Co., Ltd |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
CBY1 interacting BAR domain containing 1; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cibar1/Cibar1 |
| Background: |
C57BL/6N-Cibar1/Wtsi |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Breslow DK |
| Year: |
2018 |
| Journal: |
Nat Genet |
| Title: |
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. |
| Volume: |
50 |
| Issue: |
3 |
| Pages: |
460-471 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
6209 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
121
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
141
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lapart JA |
| Year: |
2019 |
| Journal: |
Elife |
| Title: |
Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila. |
| Volume: |
8 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu Z |
| Year: |
2020 |
| Journal: |
PLoS Biol |
| Title: |
CEP290 is essential for the initiation of ciliary transition zone assembly. |
| Volume: |
18 |
| Issue: |
12 |
| Pages: |
e3001034 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents a group of CBY1-interacting BAR domain-containing proteins formerly known as FAM92. Proteins in this family have a role in embryogenesis, being essential for ectoderm and axial mesoderm development []. They may regulate cell proliferation and apoptosis []. During spermatogenesis, these proteins regulate distal elongation of the basal-body and their anchoring to the plasma membrane and as a consequence, regulates the initiation and proper elongation of axonemal microtubules []. They have been shown to interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes [, , ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Olthof AM |
| Year: |
2021 |
| Journal: |
Nucleic Acids Res |
| Title: |
Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns. |
| Volume: |
49 |
| Issue: |
6 |
| Pages: |
3524-3545 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoque M |
| Year: |
2021 |
| Journal: |
Reproduction |
| Title: |
CEP164 is essential for efferent duct multiciliogenesis and male fertility. |
| Volume: |
162 |
| Issue: |
2 |
| Pages: |
129-139 |
|
•
•
•
•
•
|