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Search results 101 to 200 out of 258 for Ccl1

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Type Details Score
Publication
7650394 | J:28658
First Author: Youn BS
Year: 1995
Journal: J Immunol
Title: A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors.
Volume: 155
Issue: 5
Pages: 2661-7
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Publication
7594550 | J:29875
First Author: Hara T
Year: 1995
Journal: J Immunol
Title: Molecular cloning and functional characterization of a novel member of the C-C chemokine family.
Volume: 155
Issue: 11
Pages: 5352-8
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Publication
8423056 | J:4562
First Author: Byrd LG
Year: 1993
Journal: Immunogenetics
Title: Regional localization of the nu mutation on mouse chromosome 11.
Volume: 37
Issue: 2
Pages: 157-9
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Publication
27181207 | J:240215
First Author: Farmaki E
Year: 2016
Journal: Oncogene
Title: A CCL8 gradient drives breast cancer cell dissemination.
Volume: 35
Issue: 49
Pages: 6309-6318
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Publication
30294880 | J:269278
First Author: Liu X
Year: 2019
Journal: Glia
Title: MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling.
Volume: 67
Issue: 1
Pages: 101-112
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Publication
8835527 | J:31803
First Author: Baldacci PA
Year: 1996
Journal: Mamm Genome
Title: A high-resolution map around the locus Om on mouse Chromosome 11.
Volume: 7
Issue: 2
Pages: 114-6
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Publication
12383505 | J:79580
First Author: Le Bras S
Year: 2002
Journal: Gene
Title: Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.
Volume: 296
Issue: 1-2
Pages: 75-86
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Publication
7920656 | J:18978
First Author: Bollag RJ
Year: 1994
Journal: Nat Genet
Title: An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus.
Volume: 7
Issue: 3
Pages: 383-9
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Publication
1969921 | J:10423
First Author: Wilson SD
Year: 1990
Journal: J Exp Med
Title: Clustering of cytokine genes on mouse chromosome 11.
Volume: 171
Issue: 4
Pages: 1301-14
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Publication
7626882 | J:25181
First Author: Nehls M
Year: 1995
Journal: Mamm Genome
Title: YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.
Volume: 6
Issue: 5
Pages: 321-31
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Publication
7601457 | J:24223
First Author: Blackburn CC
Year: 1995
Journal: Genomics
Title: A high-resolution map of the chromosomal region surrounding the nude gene.
Volume: 26
Issue: 2
Pages: 308-17
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Publication
10995569 | J:64704
First Author: Cohen-Tannoudji M
Year: 2000
Journal: Genomics
Title: A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11.
Volume: 68
Issue: 3
Pages: 273-82
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Publication
2377456 | J:10652
First Author: Love JM
Year: 1990
Journal: Nucleic Acids Res
Title: Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites.
Volume: 18
Issue: 14
Pages: 4123-30
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Publication
8662231 | J:33556
First Author: Chiang PW
Year: 1996
Journal: Mamm Genome
Title: Linkage mapping of murine homolog of the yeast SPT6 gene to MMU11B1.
Volume: 7
Issue: 6
Pages: 459-60
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Publication
9177770 | J:40728
First Author: Krulová M
Year: 1997
Journal: Genomics
Title: IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations.
Volume: 42
Issue: 1
Pages: 11-5
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Publication
33763067 | J:307538
 
First Author: Yonebayashi S
Year: 2021
Journal: Front Immunol
Title: Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C.
Volume: 12
Pages: 620541
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Publication
12080938 | J:76755
First Author: IUIS/WHO Subcommittee on Chemokine Nomenclature.
Year: 2002
Journal: J Immunol Methods
Title: Chemokine/chemokine receptor nomenclature.
Volume: 262
Issue: 1-2
Pages: 1-3
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Publication
8884266 | J:35477
First Author: Hasson T
Year: 1996
Journal: Genomics
Title: Mapping of unconventional myosins in mouse and human.
Volume: 36
Issue: 3
Pages: 431-9
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31314754 | J:277388
First Author: Haque NS
Year: 2019
Journal: PLoS One
Title: CC chemokine CCL1 receptor CCR8 mediates conversion of mesenchymal stem cells to embryoid bodies expressing FOXP3+CCR8+ regulatory T cells.
Volume: 14
Issue: 7
Pages: e0218944
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Publication
18940934 | J:144646
First Author: Wiener Z
Year: 2008
Journal: Int Immunol
Title: IL-18 induces a marked gene expression profile change and increased Ccl1 (I-309) production in mouse mucosal mast cell homologs.
Volume: 20
Issue: 12
Pages: 1565-73
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GO Term
GO:0071610 | chemokine (C-C motif) ligand 1 production
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Allele
Ccl1<em2(CCL1)Smoc> | MGI:7288697
Name: C-C motif chemokine ligand 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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GO Term
GO:0071652 | regulation of chemokine (C-C motif) ligand 1 production
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Interaction Experiment
Liu SS (2021)
Description: The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.
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Allele
Ccl1<em1Smoc> | MGI:7288696
Name: C-C motif chemokine ligand 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428313 | C57BL/6JSmoc-Ccl1<em2(CCL1)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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GO Term
GO:0071654 | positive regulation of chemokine (C-C motif) ligand 1 production
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GO Term
GO:0071653 | negative regulation of chemokine (C-C motif) ligand 1 production
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Strain
MGI:6354582 | C57BL/6JSmoc-Ccl1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
8467814 | -
First Author: Molz L
Year: 1993
Journal: EMBO J
Title: Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity.
Volume: 12
Issue: 4
Pages: 1723-32
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Protein Domain
IPR027081 | CyclinH/Ccl1
Type: Family
Description: Cyclins are eukaryotic proteins that play an active role in controlling nuclear cell division cycles [], and regulate cyclin dependent kinases (CDKs). This entry includes cyclin-H from vertebrates, mcs2 from fission yeast and Ccl1 from budding yeasts. They are cyclins that play a role in cell cycle. They are also subunits forming the core-TFIIH basal transcription factor. Human cyclin-H regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex []. mcs2 posseses kinase activity that can be detected when myelin basic protein (MBP) is provided as an exogenous substrate []. Ccl1 is a regulatory component of the TFIIK complex, which is the protein kinase component of transcription factor IIH (TFIIH). TFIIH is essential for both basal and activated transcription and is involved in nucleotide excision repair (NER) of damaged DNA and in polymerase II transcription [].
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Publication
16769902 | -
First Author: Gaillard E
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.
Volume: 103
Issue: 25
Pages: 9548-53
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Publication
31537642 | J:285075
First Author: Knipfer L
Year: 2019
Journal: J Exp Med
Title: A CCL1/CCR8-dependent feed-forward mechanism drives ILC2 functions in type 2-mediated inflammation.
Volume: 216
Issue: 12
Pages: 2763-2777
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Publication
7715601 | -
First Author: Ritz D
Year: 1995
Journal: Mol Gen Genet
Title: The cycHJKL gene cluster plays an essential role in the biogenesis of c-type cytochromes in Bradyrhizobium japonicum.
Volume: 247
Issue: 1
Pages: 27-38
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Protein Domain
IPR003568 | Cyt_c_biogenesis_CcmF
Type: Family
Description: Within mitochondria and bacteria, a family of related proteins is involved in the assembly of periplasmic c-type cytochromes: these include CycK [], CcmF [, ], NrfE []and CcbS []. These proteins may play a role in guidance of apocytochromes and haem groups for their covalent linkage by the cytochrome-c-haem lyase. Members of the family are probably integral membrane proteins, with up to 16 predicted transmembrane (TM) helices.The gene products of the hel and ccl loci have been shown to be required specifically for the biogenesis of c-type cytochromes in the Gram-negative photosynthetic bacterium Rhodobacter capsulatus. The ccl locus contains two genes, ccl1 and ccl2, each of which possesses typical signal sequences to direct them to the periplasm []. Ccl1 is similar to proteins encoded by chloroplast and mitochondrial genes, suggesting analogous functions in these organelles. It is believed that the hel-encoded proteins are required for the export of haem to the periplasm, where it is subsequently ligated to the c-type apocytochromes []. The CycK and CycL proteins of Bradyrhizobium japonicum share up to 53% amino acid sequence identity with R. capsulatus proteins Cc11 and Cc12 proteins, respectively. CycK and CycL proteins, which are encoded by the cycHJKL-cluster, may form part of a cytochrome c-haem lyase complex whose active site faces the periplasm [].
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Publication
9235928 | J:42043
First Author: Feaver WJ
Year: 1997
Journal: J Biol Chem
Title: Genes for Tfb2, Tfb3, and Tfb4 subunits of yeast transcription/repair factor IIH. Homology to human cyclin-dependent kinase activating kinase and IIH subunits.
Volume: 272
Issue: 31
Pages: 19319-27
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Publication
16274458 | J:116833
First Author: Renninger ML
Year: 2005
Journal: Exp Dermatol
Title: Increased expression of chemokines in the skin of chronic proliferative dermatitis mutant mice.
Volume: 14
Issue: 12
Pages: 906-13
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Publication
22664870 | J:188934
First Author: Kobayashi M
Year: 2012
Journal: J Immunol
Title: Role of M2b macrophages in the acceleration of bacterial translocation and subsequent sepsis in mice exposed to whole body [137Cs] γ-irradiation.
Volume: 189
Issue: 1
Pages: 296-303
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Publication
17898285 | J:126928
First Author: Su SB
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Altered chemokine profile associated with exacerbated autoimmune pathology under conditions of genetic interferon-gamma deficiency.
Volume: 48
Issue: 10
Pages: 4616-25
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Publication
19622799 | J:153431
First Author: Shigematsu K
Year: 2009
Journal: J Leukoc Biol
Title: Enterococcus faecalis translocation in mice with severe burn injury: a pathogenic role of CCL2 and alternatively activated macrophages (M2aMphi and M2cMphi).
Volume: 86
Issue: 4
Pages: 999-1005
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Publication
30602786 | J:269382
First Author: Ito M
Year: 2019
Journal: Nature
Title: Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery.
Volume: 565
Issue: 7738
Pages: 246-250
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Publication
39044027 | J:361010
First Author: Zhang J
Year: 2024
Journal: Cell Mol Immunol
Title: Targeting the glucocorticoid receptor-CCR8 axis mediated bone marrow T cell sequestration enhances infiltration of anti-tumor T cells in intracranial cancers.
Volume: 21
Issue: 10
Pages: 1145-1157
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Publication
23999500 | J:203829
First Author: Islam SA
Year: 2013
Journal: J Exp Med
Title: Identification of human CCR8 as a CCL18 receptor.
Volume: 210
Issue: 10
Pages: 1889-98
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Publication
17404314 | J:145268
First Author: Hoshino A
Year: 2007
Journal: J Immunol
Title: Inhibition of CCL1-CCR8 interaction prevents aggregation of macrophages and development of peritoneal adhesions.
Volume: 178
Issue: 8
Pages: 5296-304
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Publication
28533380 | J:242278
First Author: Barsheshet Y
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: CCR8+FOXp3+ Treg cells as master drivers of immune regulation.
Volume: 114
Issue: 23
Pages: 6086-6091
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Publication
32948682 | J:303625
First Author: Davenport B
Year: 2020
Journal: J Immunol
Title: Chemokine Signatures of Pathogen-Specific T Cells II: Memory T Cells in Acute and Chronic Infection.
Volume: 205
Issue: 8
Pages: 2188-2206
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Protein
Q61458
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
E9PWD3
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein
Q3UUW5
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Publication
1310666 | -
First Author: Beckman DL
Year: 1992
Journal: Genes Dev
Title: Bacterial cytochromes c biogenesis.
Volume: 6
Issue: 2
Pages: 268-83
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Publication
16227271 | J:102183
First Author: Hausmann J
Year: 2005
Journal: J Virol
Title: CD8 T cells require gamma interferon to clear borna disease virus from the brain and prevent immune system-mediated neuronal damage.
Volume: 79
Issue: 21
Pages: 13509-18
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Publication
36368121 | J:344161
 
First Author: Cassidy MF
Year: 2022
Journal: Mol Immunol
Title: Splicing factor SRSF1 controls autoimmune-related molecular pathways in regulatory T cells distinct from FoxP3.
Volume: 152
Pages: 140-152
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Publication
18981157 | J:141074
First Author: Hintzen C
Year: 2008
Journal: J Immunol
Title: Oncostatin M-induced and constitutive activation of the JAK2/STAT5/CIS pathway suppresses CCL1, but not CCL7 and CCL8, chemokine expression.
Volume: 181
Issue: 10
Pages: 7341-9
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Protein
Q5DP50
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
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Protein
F6RXL0
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
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Publication
24218572 | J:202961
First Author: Guen VJ
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.
Volume: 110
Issue: 48
Pages: 19525-30
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Publication
17386261 | -
First Author: Larochelle S
Year: 2007
Journal: Mol Cell
Title: Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.
Volume: 25
Issue: 6
Pages: 839-50
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Publication
9372954 | -
First Author: Ko LJ
Year: 1997
Journal: Mol Cell Biol
Title: p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.
Volume: 17
Issue: 12
Pages: 7220-9
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Publication
9840937 | -
First Author: Schneider E
Year: 1998
Journal: Oncogene
Title: Regulation of CAK kinase activity by p53.
Volume: 17
Issue: 21
Pages: 2733-41
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Publication
16327805 | -
First Author: Larochelle S
Year: 2006
Journal: Nat Struct Mol Biol
Title: Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.
Volume: 13
Issue: 1
Pages: 55-62
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Publication
27759017 | -
 
First Author: Deshmukh AS
Year: 2016
Journal: Sci Rep
Title: Cdk7 mediates RPB1-driven mRNA synthesis in Toxoplasma gondii.
Volume: 6
Pages: 35288
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Publication
25691663 | -
First Author: Devos M
Year: 2015
Journal: Mol Cell Biol
Title: Fission yeast Cdk7 controls gene expression through both its CAK and C-terminal domain kinase activities.
Volume: 35
Issue: 9
Pages: 1480-90
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Publication
8752210 | -
First Author: Kaldis P
Year: 1996
Journal: Cell
Title: The Cdk-activating kinase (CAK) from budding yeast.
Volume: 86
Issue: 4
Pages: 553-64
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Protein Domain
IPR043198 | Cyclin/Ssn8
Type: Family
Description: Cyclins are eukaryotic proteins that play an active role in controlling nuclear cell division cycles, and regulate cyclin dependent kinases (CDKs) [].This entry represents several Cyclin families (C, L, Q, T1, T2, and H/Ccl1) and yeast RNA polymerase II holoenzyme cyclin-like subunit (also known as Ssn8/Srb11).Cyclin C can regulate both cell cycle progression and gene transcription. The Cdk8-cyclin C complex is a component of the RNA polymerase II holoenzyme [].Cyclin L is a transcriptional regulator involved in the regulation of RNA polymerase II transcription and participating in regulating the pre-mRNA splicing process [, ].Cyclin Q (also known as Cyclin M) consists of cyclin-related protein FAM58A [].Cyclin-T2 is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex [].Cyclin-H from vertebrates, mcs2 from fission yeast and Ccl1 from budding yeasts are cyclins that play a role in cell cycle [].Cyclin-T associates with CDK9 which are subunits of the positive-transcription elongation factor (P-TEFb) [].Ssn8/Srb11 is a component of the SRB8-11 complex (consists of SRB8, SSN2/SRB9, SSN3/SRB10 and SSN8/SRB11), which is a regulatory module of the mediator complex that is involved in regulation of basal and activated RNA polymerase II-dependent transcription [, ].
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Protein Domain
IPR037770 | CDK7
Type: Family
Description: Cyclin-dependent kinase 7 (CDK7) is a serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. It is activated by binding to a cyclin; binding to a different cyclin and phosphorylation of another kinase progresses the cell cycle. CDK7 binds cyclin-B and phosphorylates CDK1 during G2-M transition, and phosphorylates CDK2 and binds to cyclins during G1-S transition [, ]. CDK7 phosphorylates and activates p53 following DNA damage [], but CDK7 is then inactivated by p53, which arrests the cell cycle, allowing the cell to recover or undergo apoptosis []. CDK7 is also the catalytic subunit of the CDK-activating kinase (CAK) complex, which also contains cyclin-H (CCNH) and MAT1 [, ]. In turn, the CAK associates with the core-TFIIH to form the TFIIH basal transcription factor [].This entry includes CDK7 from animals, Kin28 from budding yeasts and Crk1 (also known as Mcs6) from fission yeasts. S. pombe possesses two CAKs, the nonessential Csk1 and the essential Mcs6 kinases, corresponding to the yeast Cak1 and the metazoan CDK7, respectively. Mcs6 modulates gene expression through both its CAK and CTD kinase activities []. Kin28 is the closest homologue of CDK7 from budding yeasts. It forms a complex with Ccl1 and Tfb3. This complex associate with TFIIH for transcription regulating activity, but does not display CAK activity []. Instead, Cak1, a single-subunit kinase distantly related to Cdk, catalyzes Cdk activation at both transitions of the budding yeast cell cycle [].
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Publication
9043133 | -
 
First Author: Page MD
Year: 1997
Journal: Microbiology
Title: The Paracoccus denitrificans ccmA, B and C genes: cloning and sequencing, and analysis of the potential of their products to form a haem or apo- c-type cytochrome transporter.
Volume: 143 ( Pt 2)
Pages: 563-76
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Protein
Q330K0
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
E9QA43
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Publication
10364329 | -
First Author: Bieniasz PD
Year: 1999
Journal: J Virol
Title: Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.
Volume: 73
Issue: 7
Pages: 5777-86
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Publication
10574912 | -
First Author: Fu TJ
Year: 1999
Journal: J Biol Chem
Title: Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription.
Volume: 274
Issue: 49
Pages: 34527-30
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Protein
Q05C55
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Publication
10024882 | -
First Author: Tirode F
Year: 1999
Journal: Mol Cell
Title: Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7.
Volume: 3
Issue: 1
Pages: 87-95
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