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Search results 101 to 200 out of 204 for Ccrl2

0.035s
Type Details Score
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945811
Age: embryonic day 11.5
Image: g01603 E11.5
Specimen Label: g01603 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945811
Age: embryonic day 15.5
Image: g01603 E15.5
Specimen Label: g01603 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Note: Expression was region specific and scattered.
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945811
Age: embryonic day 11.5
Image: g01603 E11.5
Specimen Label: g01603 E11.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945811
Age: embryonic day 11.5
Image: g01603 E11.5
Specimen Label: g01603 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945811
Age: embryonic day 15.5
Image: g01603 E15.5
Specimen Label: g01603 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945811
Age: embryonic day 15.5
Image: g01603 E15.5
Specimen Label: g01603 E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945811
Age: embryonic day 15.5
Image: g01603 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01603 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 7
Image: g01603 P7
Specimen Label: g01603 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4883135
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945811
Age: postnatal day 42
Image: g01603 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01603 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11227
Specimen Label: GUDMAP:11227
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001686
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542240
Age: embryonic day 15.5
Image: GUDMAP:11263
Specimen Label: GUDMAP:11263
Detected: false
Specimen Num: 2
Publication
First Author: Graham KL
Year: 2014
Journal: PLoS One
Title: A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease.
Volume: 9
Issue: 12
Pages: e112925
Publication
First Author: Wang F
Year: 2020
Journal: Nat Neurosci
Title: Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory.
Volume: 23
Issue: 4
Pages: 481-486
Publication
First Author: Gao JL
Year: 1995
Journal: J Biol Chem
Title: Cloning and differential tissue-specific expression of three mouse beta chemokine receptor-like genes, including the gene for a functional macrophage inflammatory protein-1 alpha receptor.
Volume: 270
Issue: 29
Pages: 17494-501
Publication
First Author: Zhi JJ
Year: 2023
Journal: J Neurosci
Title: Insufficient Oligodendrocyte Turnover in Optic Nerve Contributes to Age-Related Axon Loss and Visual Deficits.
Volume: 43
Issue: 11
Pages: 1859-1870
Publication
First Author: Quackenbush EJ
Year: 1997
Journal: J Leukoc Biol
Title: Eotaxin influences the development of embryonic hematopoietic progenitors in the mouse.
Volume: 62
Issue: 5
Pages: 661-6
Publication
First Author: Post TW
Year: 1995
Journal: J Immunol
Title: Molecular characterization of two murine eosinophil beta chemokine receptors.
Volume: 155
Issue: 11
Pages: 5299-305
Publication
First Author: Kiss H
Year: 2002
Journal: Mamm Genome
Title: Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.
Volume: 13
Issue: 11
Pages: 646-55
Publication
First Author: IUIS/WHO Subcommittee on Chemokine Nomenclature.
Year: 2002
Journal: J Immunol Methods
Title: Chemokine/chemokine receptor nomenclature.
Volume: 262
Issue: 1-2
Pages: 1-3
Publication        
First Author: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
Year: 2001
Title: GenBank Record Derived Information
Publication      
First Author: Deltagen Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Deltagen, Inc. mice into public repositories
Publication
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
Publication
First Author: Shalom-Barak T
Year: 2012
Journal: Dev Biol
Title: Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.
Volume: 372
Issue: 1
Pages: 143-55
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: C-C motif chemokine receptor-like 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: C-C motif chemokine receptor-like 2; endonuclease-mediated mutation 1, Xiaoxiao Wan
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Gosling J
Year: 2000
Journal: J Immunol
Title: Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK.
Volume: 164
Issue: 6
Pages: 2851-6
Publication
First Author: Vinet J
Year: 2013
Journal: Br J Pharmacol
Title: Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR.
Volume: 168
Issue: 6
Pages: 1375-87
Publication
First Author: Lucas B
Year: 2015
Journal: Eur J Immunol
Title: CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice.
Volume: 45
Issue: 2
Pages: 574-83
Publication
First Author: Comerford I
Year: 2006
Journal: Eur J Immunol
Title: The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro.
Volume: 36
Issue: 7
Pages: 1904-16
Protein Domain
Type: Family
Description: Just like classical chemokine receptors, atypical chemokine receptors (ACKRs) are seven-transmembrane-helix (7TM) receptors that bind chemokines []. However, they lack the canonical DRYLAIV motif necessary for GPCR coupling to G proteins and induction of classical signalling pathways. Instead, ACKRs internalise their chemokine ligands, which may subsequently affect chemokine availability. The ACKR family comprises five members: Duffy Antigen Receptor for Chemokines (DARC, ACKR1), D6 (ACKR2), CXCR7 (ACKR3), CCRL1 (ACKR4) and CCRL2 (ACKR5) [].Atypical chemokine receptor 4 (ACKR4/CCRL1/CCX-CKR) binds and scavenges the ligands of the chemokine receptors CCR7 and CCR9 (CCL19/CCL21 and CCL25, respectively) and targets them for subsequent lysosomal degradation [, ]. Apart from being a scavenger for chemokines, it may prevent CXCR3-induced chemotaxis by heteromerisation []. ACKR4 appears to have a mayor role in normal thymus development and function [].
Publication
First Author: Nibbs RJ
Year: 2013
Journal: Nat Rev Immunol
Title: Immune regulation by atypical chemokine receptors.
Volume: 13
Issue: 11
Pages: 815-29
Publication
First Author: Bachelerie F
Year: 2014
Journal: Nat Immunol
Title: New nomenclature for atypical chemokine receptors.
Volume: 15
Issue: 3
Pages: 207-8
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First Author: Burns JM
Year: 2006
Journal: J Exp Med
Title: A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development.
Volume: 203
Issue: 9
Pages: 2201-13
Publication
First Author: Sierro F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.
Volume: 104
Issue: 37
Pages: 14759-64
Publication
First Author: Gerrits H
Year: 2008
Journal: Genesis
Title: Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice.
Volume: 46
Issue: 5
Pages: 235-45
Publication
First Author: Naumann U
Year: 2010
Journal: PLoS One
Title: CXCR7 functions as a scavenger for CXCL12 and CXCL11.
Volume: 5
Issue: 2
Pages: e9175
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First Author: Shimizu N
Year: 2000
Journal: J Virol
Title: A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses.
Volume: 74
Issue: 2
Pages: 619-26
Publication
First Author: Rajagopal S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7.
Volume: 107
Issue: 2
Pages: 628-32
Publication
First Author: Hattermann K
Year: 2010
Journal: Cancer Res
Title: The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
Volume: 70
Issue: 8
Pages: 3299-308
Publication
First Author: Miao Z
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature.
Volume: 104
Issue: 40
Pages: 15735-40
Publication
First Author: Zabel BA
Year: 2009
Journal: J Immunol
Title: Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands.
Volume: 183
Issue: 5
Pages: 3204-11