Type |
Details |
Score |
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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•
•
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Publication |
First Author: |
Bowen MA |
Year: |
1995 |
Journal: |
J Exp Med |
Title: |
Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. |
Volume: |
181 |
Issue: |
6 |
Pages: |
2213-20 |
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•
•
•
•
•
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Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
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•
•
•
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Publication |
First Author: |
Kashyap R |
Year: |
2015 |
Journal: |
Front Pharmacol |
Title: |
Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells. |
Volume: |
6 |
|
Pages: |
241 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
91
 |
Fragment?: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Kang BS |
Year: |
2003 |
Journal: |
Structure |
Title: |
PDZ tandem of human syntenin: crystal structure and functional properties. |
Volume: |
11 |
Issue: |
4 |
Pages: |
459-68 |
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•
•
•
•
•
|
Publication |
First Author: |
Zimmermann P |
Year: |
2001 |
Journal: |
Mol Biol Cell |
Title: |
Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments. |
Volume: |
12 |
Issue: |
2 |
Pages: |
339-50 |
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•
•
•
•
•
|
Publication |
First Author: |
Geijsen N |
Year: |
2001 |
Journal: |
Science |
Title: |
Cytokine-specific transcriptional regulation through an IL-5Ralpha interacting protein. |
Volume: |
293 |
Issue: |
5532 |
Pages: |
1136-8 |
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•
•
•
•
•
|
Publication |
First Author: |
Grootjans JJ |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Syntenin, a PDZ protein that binds syndecan cytoplasmic domains. |
Volume: |
94 |
Issue: |
25 |
Pages: |
13683-8 |
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•
•
•
•
•
|
Publication |
First Author: |
Kegelman TP |
Year: |
2015 |
Journal: |
Expert Opin Ther Targets |
Title: |
Targeting tumor invasion: the roles of MDA-9/Syntenin. |
Volume: |
19 |
Issue: |
1 |
Pages: |
97-112 |
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•
•
•
•
•
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Publication |
First Author: |
Liu X |
Year: |
2014 |
Journal: |
Oncol Rep |
Title: |
Overexpression of syntenin enhances hepatoma cell proliferation and invasion: potential roles in human hepatoma. |
Volume: |
32 |
Issue: |
6 |
Pages: |
2810-6 |
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•
•
•
•
•
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Publication |
First Author: |
Philley JV |
Year: |
2016 |
Journal: |
J Cell Physiol |
Title: |
MDA-9/Syntenin Control. |
Volume: |
231 |
Issue: |
3 |
Pages: |
545-50 |
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•
•
•
•
•
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Publication |
First Author: |
Hwangbo C |
Year: |
2016 |
Journal: |
Oncogene |
Title: |
Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization. |
Volume: |
35 |
Issue: |
3 |
Pages: |
389-401 |
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•
•
•
•
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Protein Domain |
Type: |
Family |
Description: |
Syntenin-1 was originally identified as a syndecan-binding PDZ protein []. Later, Syntenin-1 is found to be a scaffolding protein that interacts with several membrane receptors, such as the lymphocyte receptor CD6 and the interleukin 5 (IL-5) receptor [, , ]. It has diverse cellular roles including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis [, , , ]. Its structure has been solved [, ]. |
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•
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Publication |
First Author: |
Cayrol R |
Year: |
2008 |
Journal: |
Nat Immunol |
Title: |
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system. |
Volume: |
9 |
Issue: |
2 |
Pages: |
137-45 |
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•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2022 |
Journal: |
JCI Insight |
Title: |
CDCP1 regulates retinal pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis. |
Volume: |
7 |
Issue: |
18 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
298
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
298
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
298
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
209
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
298
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
249
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
199
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
298
 |
Fragment?: |
false |
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•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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