Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603925 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 17.5 |
Image: |
6C |
Note: |
Expression is in most tissues. |
Specimen Label: |
6C |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1842625 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 17.5 |
Image: |
6C |
|
Specimen Label: |
6C |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Strong |
Sex: |
Male |
Emaps: |
EMAPS:3575728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5498271 |
Age: |
postnatal adult |
Image: |
4A/B |
|
Specimen Label: |
4A/B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5498271 |
Age: |
postnatal adult |
Image: |
4A/B |
|
Specimen Label: |
4A/B |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 10.7 |
Image: |
6A |
|
Specimen Label: |
6A |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 13.5 |
Image: |
6B |
|
Specimen Label: |
6B |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684625 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 17.5 |
Image: |
6D |
|
Specimen Label: |
6D |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1624717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 10.7 |
Image: |
6A |
|
Specimen Label: |
6A |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1842521 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 13.5 |
Image: |
6B |
Note: |
Expression is in the adrenal gland. |
Specimen Label: |
6B |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876825 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 17.5 |
Image: |
6E |
|
Specimen Label: |
6E |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Weak |
Sex: |
Female |
Emaps: |
EMAPS:3563328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5498271 |
Age: |
postnatal adult |
Image: |
4C/D |
|
Specimen Label: |
4C/D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 10.7 |
Image: |
6A |
|
Specimen Label: |
6A |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5498271 |
Age: |
postnatal adult |
Image: |
4C/D |
Note: |
In preantral and antral follicles. |
Specimen Label: |
4C/D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 10.7 |
Image: |
6A |
|
Specimen Label: |
6A |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5498269 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-07-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5498271 |
Age: |
embryonic day 13.5 |
Image: |
6B |
|
Specimen Label: |
6B |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto H |
Year: |
1999 |
Journal: |
Genomics |
Title: |
Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor. |
Volume: |
58 |
Issue: |
1 |
Pages: |
90-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gariboldi M |
Year: |
1994 |
Journal: |
Genomics |
Title: |
Genetic mapping of the mouse CDC25Mm gene, a ras-specific guanine nucleotide-releasing factor, to chromosome 9. |
Volume: |
21 |
Issue: |
2 |
Pages: |
451-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hardiman G |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Genetic structure and chromosomal mapping of MyD88. |
Volume: |
45 |
Issue: |
2 |
Pages: |
332-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Motoyama N |
Year: |
2004 |
Journal: |
Curr Opin Genet Dev |
Title: |
DNA damage tumor suppressor genes and genomic instability. |
Volume: |
14 |
Issue: |
1 |
Pages: |
11-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang KH |
Year: |
2012 |
Journal: |
J Cell Sci |
Title: |
Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death. |
Volume: |
125 |
Issue: |
Pt 21 |
Pages: |
5124-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li N |
Year: |
2023 |
Journal: |
Stem Cell Reports |
Title: |
CFIm-mediated alternative polyadenylation safeguards the development of mammalian pre-implantation embryos. |
Volume: |
18 |
Issue: |
1 |
Pages: |
81-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Su YQ |
Year: |
2012 |
Journal: |
Science |
Title: |
MARF1 regulates essential oogenic processes in mice. |
Volume: |
335 |
Issue: |
6075 |
Pages: |
1496-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mitchem KL |
Year: |
2002 |
Journal: |
Hum Mol Genet |
Title: |
Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6. |
Volume: |
11 |
Issue: |
16 |
Pages: |
1887-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Houlihan SL |
Year: |
2014 |
Journal: |
Elife |
Title: |
The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation. |
Volume: |
3 |
|
Pages: |
e03297 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kafer GR |
Year: |
2020 |
Journal: |
Front Cell Dev Biol |
Title: |
A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis. |
Volume: |
8 |
|
Pages: |
416 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tapias A |
Year: |
2014 |
Journal: |
Cell Stem Cell |
Title: |
Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions. |
Volume: |
14 |
Issue: |
5 |
Pages: |
632-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Otto T |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. |
Volume: |
114 |
Issue: |
40 |
Pages: |
10660-10665 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lock LF |
Year: |
1996 |
Journal: |
Mamm Genome |
Title: |
The Cdc25 genes map to mouse chromosomes 2, 9, and 18. |
Volume: |
7 |
Issue: |
10 |
Pages: |
771-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie L |
Year: |
2012 |
Journal: |
Dev Cell |
Title: |
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. |
Volume: |
23 |
Issue: |
2 |
Pages: |
280-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tane S |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes. |
Volume: |
289 |
Issue: |
26 |
Pages: |
18033-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki T |
Year: |
2019 |
Journal: |
Development |
Title: |
Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. |
Volume: |
146 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yu C |
Year: |
2016 |
Journal: |
Cell Res |
Title: |
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. |
Volume: |
26 |
Issue: |
3 |
Pages: |
275-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu J |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. |
Volume: |
111 |
Issue: |
28 |
Pages: |
E2851-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lexicon Genetics Inc |
Year: |
2005 |
Journal: |
MGI Direct Data Submission |
Title: |
NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koss M |
Year: |
2012 |
Journal: |
Dev Cell |
Title: |
Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. |
Volume: |
22 |
Issue: |
5 |
Pages: |
913-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Backcross DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX BSS Panel Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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Publication |
First Author: |
Ray D |
Year: |
2007 |
Journal: |
Cancer Res |
Title: |
Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. |
Volume: |
67 |
Issue: |
3 |
Pages: |
984-91 |
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•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
514
 |
Fragment?: |
false |
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•
•
•
•
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Publication |
First Author: |
Biswas K |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage. |
Volume: |
9 |
Issue: |
1 |
Pages: |
537 |
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•
•
•
•
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Publication |
First Author: |
Gautier EF |
Year: |
2012 |
Journal: |
Blood |
Title: |
The cell cycle regulator CDC25A is a target for JAK2V617F oncogene. |
Volume: |
119 |
Issue: |
5 |
Pages: |
1190-9 |
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•
•
•
•
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Publication |
First Author: |
Chiu YT |
Year: |
2009 |
Journal: |
J Mol Biol |
Title: |
CDC25A functions as a novel Ar corepressor in prostate cancer cells. |
Volume: |
385 |
Issue: |
2 |
Pages: |
446-56 |
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•
•
•
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Publication |
First Author: |
Myer DL |
Year: |
2011 |
Journal: |
Mutat Res |
Title: |
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. |
Volume: |
714 |
Issue: |
1-2 |
Pages: |
1-10 |
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•
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Publication |
First Author: |
Zhuang S |
Year: |
2000 |
Journal: |
Mutat Res |
Title: |
Genetic analysis of Raf1, Mdm2, c-Myc, Cdc25a and Cdc25b proto-oncogenes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced lymphomas in B6C3F1 mice. |
Volume: |
452 |
Issue: |
1 |
Pages: |
19-26 |
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•
•
•
•
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Publication |
First Author: |
Llobet-Navas D |
Year: |
2014 |
Journal: |
Mol Cell Biol |
Title: |
The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells. |
Volume: |
34 |
Issue: |
23 |
Pages: |
4216-31 |
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Publication |
First Author: |
Nguyen DX |
Year: |
2002 |
Journal: |
J Virol |
Title: |
Human papillomavirus type 16 E7 maintains elevated levels of the cdc25A tyrosine phosphatase during deregulation of cell cycle arrest. |
Volume: |
76 |
Issue: |
2 |
Pages: |
619-32 |
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Pathway |
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Publication |
First Author: |
Jinno S |
Year: |
1994 |
Journal: |
EMBO J |
Title: |
Cdc25A is a novel phosphatase functioning early in the cell cycle. |
Volume: |
13 |
Issue: |
7 |
Pages: |
1549-56 |
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Allele |
Name: |
transgene insertion, Sophia Y Tsai |
Allele Type: |
Transgenic |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
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Publication |
First Author: |
McMurray HR |
Year: |
2001 |
Journal: |
Int J Exp Pathol |
Title: |
Biology of human papillomaviruses. |
Volume: |
82 |
Issue: |
1 |
Pages: |
15-33 |
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•
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•
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Protein Domain |
Type: |
Family |
Description: |
This family includes the E7 oncoprotein from various papillomaviruses []. Along with E5 and E6 their activities seem to be especially important for viral oncogenesis. E5 is located at the cell surface and reduces cell gap-gap junction communication. In cervical cancer E5 is expressed in earlier stages of neoplastic transformation of the cervical epithelium during viral infection. The role of E7 is less well understood but it has been shown to impede growth arrest signals in both NIH 3T3 cells and HFKs and that this correlates with elevated cdc25A gene expression. This deregulation of cdc25A islinked to disruption of cell cycle arrest []. |
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Publication |
First Author: |
Pandey A |
Year: |
2024 |
Journal: |
Sci Adv |
Title: |
Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome. |
Volume: |
10 |
Issue: |
4 |
Pages: |
eadh3409 |
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•
•
•
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Publication |
First Author: |
Leduc I |
Year: |
2000 |
Journal: |
Int Immunol |
Title: |
The Pim-1 kinase stimulates maturation of TCRbeta-deficient T cell progenitors: implications for the mechanism of Pim-1 action. |
Volume: |
12 |
Issue: |
10 |
Pages: |
1389-96 |
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•
•
•
•
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Publication |
First Author: |
Gao X |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells. |
Volume: |
11 |
Issue: |
1 |
Pages: |
3904 |
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•
•
•
•
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Publication |
First Author: |
Liu X |
Year: |
2017 |
Journal: |
EMBO J |
Title: |
The E3 ubiquitin ligase APC/CCdh1 degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis. |
Volume: |
36 |
Issue: |
24 |
Pages: |
3666-3681 |
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•
•
•
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Publication |
First Author: |
Lin H |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
MARCH3 attenuates IL-1β-triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI. |
Volume: |
115 |
Issue: |
49 |
Pages: |
12483-12488 |
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•
•
•
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Publication |
First Author: |
Tetsu O |
Year: |
1998 |
Journal: |
Immunity |
Title: |
mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25. |
Volume: |
9 |
Issue: |
4 |
Pages: |
439-48 |
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•
•
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Publication |
First Author: |
Yao Y |
Year: |
1999 |
Journal: |
Oncogene |
Title: |
Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice. |
Volume: |
18 |
Issue: |
37 |
Pages: |
5159-66 |
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•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
546
 |
Fragment?: |
false |
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•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
476
 |
Fragment?: |
false |
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•
•
•
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Publication |
First Author: |
Stolfi C |
Year: |
2014 |
Journal: |
Cell Death Dis |
Title: |
A functional role for Smad7 in sustaining colon cancer cell growth and survival. |
Volume: |
5 |
|
Pages: |
e1073 |
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•
•
•
•
•
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Publication |
First Author: |
Grimm SL |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. |
Volume: |
280 |
Issue: |
43 |
Pages: |
36301-9 |
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•
•
•
•
•
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Publication |
First Author: |
Hsu SH |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure. |
Volume: |
183 |
Issue: |
6 |
Pages: |
1719-30 |
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•
•
•
•
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Publication |
First Author: |
Wang X |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. |
Volume: |
99 |
Issue: |
26 |
Pages: |
16881-6 |
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•
•
•
•
•
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Publication |
First Author: |
Madson JG |
Year: |
2009 |
Journal: |
Am J Pathol |
Title: |
Erbb2 suppresses DNA damage-induced checkpoint activation and UV-induced mouse skin tumorigenesis. |
Volume: |
174 |
Issue: |
6 |
Pages: |
2357-66 |
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•
•
•
•
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Publication |
First Author: |
Chen MS |
Year: |
2001 |
Journal: |
Mol Cell Biol |
Title: |
Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase. |
Volume: |
21 |
Issue: |
12 |
Pages: |
3853-61 |
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•
•
•
•
•
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Publication |
First Author: |
Ferguson AM |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. |
Volume: |
25 |
Issue: |
7 |
Pages: |
2853-60 |
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