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Search results 101 to 200 out of 238 for Cdc25c

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 6B
Specimen Label: 6B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 6C
Specimen Label: 6C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 6B
Note: Expression is in early elongated and round spermatids.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 6C
Note: Expression is in early elongated and round spermatids.
Specimen Label: 6C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Present
Sex: Female
Emaps: EMAPS:3526728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:4416727
Assay Type: RNA in situ
Annotation Date: 2024-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7623562
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Present
Sex: Female
Emaps: EMAPS:3563328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5140507
Assay Type: RNA in situ
Annotation Date: 2011-08-22
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:5140520
Age: postnatal adult
Image: 7A
Specimen Label: 7A
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6444114
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604011
Pattern: Single cells
Stage: TS11
Assay Id: MGI:6445619
Age: embryonic day 7.5
Image: 7A
Note: The phosphorylated protein indicates cells at the G2/M checkpoint.
Specimen Label: 7A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6444114
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360407
Pattern: Single cells
Stage: TS07
Assay Id: MGI:6445619
Age: embryonic day 5.5
Image: 7C
Note: The phosphorylated protein indicates cells at the G2/M checkpoint.
Specimen Label: 7C
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6444114
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360408
Pattern: Single cells
Stage: TS08
Assay Id: MGI:6445619
Age: embryonic day 7.5
Image: 7B
Note: The phosphorylated protein indicates cells at the G2/M checkpoint. There were significantly more of these cells in the mutant compared to wild type. Mutants appear to stall just prior to the onset of gastrulation.
Specimen Label: 7B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6444114
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360408
Pattern: Single cells
Stage: TS08
Assay Id: MGI:6445619
Age: embryonic day 7.5
Note: These results were reported in Fig. 7E. The phosphorylated protein indicates cells at the G2/M checkpoint. There were significantly more of these cells in the mutant compared to wild type. Mutants appear to stall just prior to the onset of gastrulation.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6444114
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360408
Pattern: Single cells
Stage: TS08
Assay Id: MGI:6445619
Age: embryonic day 7.5
Note: These results were reported in Fig. 7E. The phosphorylated protein indicates cells at the G2/M checkpoint. There were significantly more of these cells in the mutant compared to wild type. Mutants appear to stall just prior to the onset of gastrulation.
Specimen Label: not shown
Detected: true
Specimen Num: 4
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Publication
9199335 | J:41106
First Author: Busfield SJ
Year: 1997
Journal: Mol Cell Biol
Title: Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus.
Volume: 17
Issue: 7
Pages: 4007-14
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Publication
28607169 | J:353775
First Author: Iyirhiaro GO
Year: 2017
Journal: J Neurosci
Title: Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo.
Volume: 37
Issue: 28
Pages: 6729-6740
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Publication
7690561 | J:14453
First Author: Yokoi H
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Non-radioisotopic quantitative RT-PCR to detect changes in mRNA levels during early mouse embryo development.
Volume: 195
Issue: 2
Pages: 769-75
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Publication
28094252 | J:243924
 
First Author: Xu X
Year: 2017
Journal: Nat Commun
Title: A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Volume: 8
Pages: 14059
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Publication
12471023 | J:81991
First Author: Schmidt EE
Year: 2003
Journal: J Biol Chem
Title: Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein.
Volume: 278
Issue: 8
Pages: 6168-74
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Publication
25002142 | J:215645
First Author: Hung V
Year: 2014
Journal: Mol Cell
Title: Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging.
Volume: 55
Issue: 2
Pages: 332-41
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Publication
32527007 | J:292025
 
First Author: Gómez-Redondo I
Year: 2020
Journal: Int J Mol Sci
Title: Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.
Volume: 21
Issue: 11
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Publication
28659827 | J:307972
 
First Author: Farrell ET
Year: 2017
Journal: Front Physiol
Title: Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy.
Volume: 8
Pages: 414
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Publication
22442484 | J:181834
First Author: Su YQ
Year: 2012
Journal: Science
Title: MARF1 regulates essential oogenic processes in mice.
Volume: 335
Issue: 6075
Pages: 1496-9
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Publication
30410445 | J:307828
 
First Author: Farrell E
Year: 2018
Journal: Front Physiol
Title: Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling.
Volume: 9
Pages: 1442
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Publication
29530878 | J:264126
 
First Author: Yaghmaeian Salmani B
Year: 2018
Journal: Development
Title: Evolutionarily conserved anterior expansion of the central nervous system promoted by a common PcG-Hox program.
Volume: 145
Issue: 7
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Publication
24143284 | J:201041
First Author: Park DS
Year: 2013
Journal: Biol Open
Title: Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system.
Volume: 2
Issue: 9
Pages: 968-78
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Publication
8854867 | J:35909
First Author: Lock LF
Year: 1996
Journal: Mamm Genome
Title: The Cdc25 genes map to mouse chromosomes 2, 9, and 18.
Volume: 7
Issue: 10
Pages: 771-2
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Publication
31634485 | J:294628
 
First Author: Gong H
Year: 2019
Journal: J Mol Cell Cardiol
Title: Shp2 in myocytes is essential for cardiovascular and neointima development.
Volume: 137
Pages: 71-81
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Publication
21093383 | J:168590
First Author: LeBoeuf M
Year: 2010
Journal: Dev Cell
Title: Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells.
Volume: 19
Issue: 6
Pages: 807-18
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Publication
30389914 | J:267889
First Author: Moon S
Year: 2018
Journal: Cell Death Dis
Title: Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Volume: 9
Issue: 11
Pages: 1118
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Publication
32376682 | J:290315
 
First Author: Cheong A
Year: 2020
Journal: Development
Title: Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation.
Volume: 147
Issue: 10
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Publication
21737879 | J:176173
First Author: Passemard S
Year: 2011
Journal: J Clin Invest
Title: VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
Volume: 121
Issue: 8
Pages: 3071-87
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Publication
34851661 | J:316473
First Author: Tampakakis E
Year: 2021
Journal: Sci Adv
Title: Heart neurons use clock genes to control myocyte proliferation.
Volume: 7
Issue: 49
Pages: eabh4181
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Publication
30635555 | J:270210
First Author: Loo L
Year: 2019
Journal: Nat Commun
Title: Single-cell transcriptomic analysis of mouse neocortical development.
Volume: 10
Issue: 1
Pages: 134
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
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First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
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First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
21041626 | J:245344
First Author: Wang R
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation.
Volume: 107
Issue: 46
Pages: 19885-90
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Publication
9543386 | J:261160
First Author: Peng CY
Year: 1998
Journal: Cell Growth Differ
Title: C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.
Volume: 9
Issue: 3
Pages: 197-208
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Publication
7479023 | J:29447
First Author: Zwicker J
Year: 1995
Journal: Nucleic Acids Res
Title: Cell cycle regulation of cdc25C transcription is mediated by the periodic repression of the glutamine-rich activators NF-Y and Sp1.
Volume: 23
Issue: 19
Pages: 3822-30
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Protein
P48967
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Publication
10761933 | J:61319
First Author: Chen P
Year: 2000
Journal: Cell
Title: The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation.
Volume: 100
Issue: 6
Pages: 681-92
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Publication
19164942 | -
First Author: Petrinac S
Year: 2009
Journal: Cell Cycle
Title: Polo-like kinase 4 phosphorylates Chk2.
Volume: 8
Issue: 2
Pages: 327-9
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Publication
15173822 | -
First Author: Barr FA
Year: 2004
Journal: Nat Rev Mol Cell Biol
Title: Polo-like kinases and the orchestration of cell division.
Volume: 5
Issue: 6
Pages: 429-40
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Publication
26786872 | -
First Author: Vaid R
Year: 2016
Journal: Protein Pept Lett
Title: Functions of Polo-Like Kinases: A Journey From Yeast To Humans.
Volume: 23
Issue: 2
Pages: 185-97
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Publication
21968988 | -
First Author: Nigg EA
Year: 2011
Journal: Nat Cell Biol
Title: The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries.
Volume: 13
Issue: 10
Pages: 1154-60
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Publication
16326102 | -
First Author: Bettencourt-Dias M
Year: 2005
Journal: Curr Biol
Title: SAK/PLK4 is required for centriole duplication and flagella development.
Volume: 15
Issue: 24
Pages: 2199-207
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Publication
16244668 | -
First Author: Habedanck R
Year: 2005
Journal: Nat Cell Biol
Title: The Polo kinase Plk4 functions in centriole duplication.
Volume: 7
Issue: 11
Pages: 1140-6
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Publication
26755742 | -
First Author: Hori A
Year: 2016
Journal: EMBO Rep
Title: A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation.
Volume: 17
Issue: 3
Pages: 326-37
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Publication
17383880 | -
First Author: Nigg EA
Year: 2007
Journal: Trends Cell Biol
Title: Centrosome duplication: of rules and licenses.
Volume: 17
Issue: 5
Pages: 215-21
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Publication
18239451 | -
First Author: Bonni S
Year: 2008
Journal: Cell Cycle
Title: Human Plk4 phosphorylates Cdc25C.
Volume: 7
Issue: 4
Pages: 545-7
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Protein Domain
IPR033700 | Plk4
Type: Family
Description: Polo-like kinases (Plks) belong to the serine/threonine kinase subfamily, and are characterized by the presence of the signature motif called Polo-box domain. Plks are key regulators of cell cycle and cell division in eukaryotes [, ]. Unicellular organisms contain one Plk whereas higher eukaryotes have as many as four Plks: Plk1, Plk2, Plk3 andPlk4.Plk4 (also called Sak) is the most structurally divergent member of the Plks. It plays a pivotal role in centriole duplication [, , , , ]and is required for centriolar satellite function and ciliogenesis []. Substrates identified for Plk4 include Cdc25C and Chk2 [, ].
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Publication
9836640 | J:61425
First Author: Matsuoka S
Year: 1998
Journal: Science
Title: Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Volume: 282
Issue: 5395
Pages: 1893-7
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Publication
9278511 | J:42767
First Author: Sanchez Y
Year: 1997
Journal: Science
Title: Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Volume: 277
Issue: 5331
Pages: 1497-501
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Publication
19699177 | J:154327
First Author: Cheng Y
Year: 2009
Journal: Arch Biochem Biophys
Title: Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells.
Volume: 490
Issue: 1
Pages: 70-5
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Publication
37682709 | J:351657
First Author: Xu N
Year: 2023
Journal: Cell Rep
Title: PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C.
Volume: 42
Issue: 9
Pages: 113041
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Publication
8798343 | J:35815
First Author: Wang W
Year: 1996
Journal: J Mol Evol
Title: Molecular evolution of the 14-3-3 protein family.
Volume: 43
Issue: 4
Pages: 384-98
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Publication
16103198 | -
First Author: Surjit M
Year: 2005
Journal: J Virol
Title: The severe acute respiratory syndrome coronavirus nucleocapsid protein is phosphorylated and localizes in the cytoplasm by 14-3-3-mediated translocation.
Volume: 79
Issue: 17
Pages: 11476-86
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Publication
11080204 | -
First Author: Malaspina A
Year: 2000
Journal: J Neurochem
Title: A 14-3-3 mRNA is up-regulated in amyotrophic lateral sclerosis spinal cord.
Volume: 75
Issue: 6
Pages: 2511-20
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Publication
12527748 | -
First Author: Martin D
Year: 2003
Journal: J Cell Biol
Title: Tenascin-C signaling through induction of 14-3-3 tau.
Volume: 160
Issue: 2
Pages: 171-5
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Protein Domain
IPR042584 | 14-3-3_theta
Type: Family
Description: 14-3-3 tau/theta (tau in humans, theta in mice) isoform is encoded by the YWHAQ gene in humans and plays an important role in controlling apoptosis through interactions with ASK1, c-jun NH-terminal kinase, and p38 mitogen-activated protein kinase (MAPK). Its interaction with CDC25c regulates entry into the cell cycle and subsequent interaction with Bad prevents apoptosis. 14-3-3 theta protein expression is induced in patients with amyotrophic lateral sclerosis []. 14-3-3 tau is often overexpressed in breast cancer, which is associated with the downregulation of p21, a p53 target gene, and thus leads to tamoxifen resistance in MCF7 breast cancer cells and shorter patientsurvival. Therefore, 14-3-3 tau may be a potential therapeutic target in breast cancer []. Additionally, 14-3-3 theta mediates nucleocytoplasmic shuttling of the coronavirus nucleocapsid protein which causes severe acute respiratory syndrome []. 14-3-3 domain is an essential part of 14-3-3 proteins, a ubiquitous class of regulatory, phosphoserine/threonine-binding proteins found in all eukaryotic cells, including yeast, protozoa and mammalian cells [].
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Publication
17079455 | J:114921
First Author: Knock E
Year: 2006
Journal: Cancer Res
Title: Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators polo-like kinase 1 and cell division cycle 25c.
Volume: 66
Issue: 21
Pages: 10349-56
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Publication
11912493 | J:87011
First Author: Lincoln AJ
Year: 2002
Journal: Nat Genet
Title: Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation.
Volume: 30
Issue: 4
Pages: 446-9
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Publication
15459478 | J:95087
First Author: Park CE
Year: 2004
Journal: Cells Tissues Organs
Title: Expression of wee1 and its related cell cycle components in mouse early stage follicles.
Volume: 177
Issue: 4
Pages: 221-8
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Publication
12941695 | J:326246
First Author: Müller J
Year: 2003
Journal: EMBO J
Title: Functional analysis of C-TAK1 substrate binding and identification of PKP2 as a new C-TAK1 substrate.
Volume: 22
Issue: 17
Pages: 4431-42
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Publication
9788881 | J:51521
 
First Author: Gowdy PM
Year: 1998
Journal: J Cell Sci
Title: Entry into mitosis without Cdc2 kinase activation.
Volume: 111 ( Pt 22)
Pages: 3401-10
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Publication
18367163 | J:136042
First Author: Solc P
Year: 2008
Journal: Dev Biol
Title: CDC25A phosphatase controls meiosis I progression in mouse oocytes.
Volume: 317
Issue: 1
Pages: 260-9
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Publication
18345025 | J:138506
First Author: Wang IC
Year: 2008
Journal: Oncogene
Title: Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors.
Volume: 27
Issue: 30
Pages: 4137-49
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Publication
18538787 | J:168882
First Author: Gabant G
Year: 2008
Journal: J Mol Biol
Title: Autophosphorylated residues involved in the regulation of human chk2 in vitro.
Volume: 380
Issue: 3
Pages: 489-503
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Publication
22064854 | J:197738
First Author: Müller GA
Year: 2012
Journal: Nucleic Acids Res
Title: The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.
Volume: 40
Issue: 4
Pages: 1561-78
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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