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Search results 101 to 151 out of 151 for Cdnf

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Note: Expression most intense in hippocampus and thalamus.
Specimen Label: S3e
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Note: Expression most intense in hippocampus and thalamus.
Specimen Label: S3n
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6719233
Age: postnatal day 1
Specimen Label: S3u
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6719235
Age: postnatal day 1
Specimen Label: S5f
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719235
Age: postnatal day 10
Specimen Label: S5b
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6719233
Age: postnatal day 1
Specimen Label: S3q
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:3527628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719235
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Specimen Label: S3a
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6719224
Assay Type: RNA in situ
Annotation Date: 2021-07-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719233
Age: postnatal day 10
Specimen Label: S3k
Specimen Num: 6
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Publication
32005751 | J:287361
 
First Author: Pakarinen E
Year: 2020
Journal: eNeuro
Title: MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
Volume: 7
Issue: 1
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
27425895 | -
First Author: Lindahl M
Year: 2017
Journal: Neurobiol Dis
Title: Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential.
Volume: 97
Issue: Pt B
Pages: 90-102
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Allele
Cdnf<em1Smoc> | MGI:7288913
Name: cerebral dopamine neurotrophic factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7717983 | C57BL/6JSmoc-Cdnf<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
25975173 | J:227149
 
First Author: Kemppainen S
Year: 2015
Journal: Behav Brain Res
Title: Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice.
Volume: 291
Pages: 1-11
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Publication
17507765 | -
First Author: Mizobuchi N
Year: 2007
Journal: Cell Struct Funct
Title: ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element.
Volume: 32
Issue: 1
Pages: 41-50
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Publication
16462600 | -
First Author: Zhou C
Year: 2006
Journal: Neuroreport
Title: Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release.
Volume: 17
Issue: 3
Pages: 293-7
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Protein Domain
IPR019345 | ARMET_C
Type: Domain
Description: This entry represents the C-terminal domain of ARMET.ARMET, also known as mesencephalic astrocyte-derived neurotrophic factor (MANF) or arginine-rich protein, is a small protein of approximately 170 residues which contains four di-sulphide bridges that are highly conserved from nematodes to humans. It is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress []. ARMET from Rattus norvegicus (Rat) selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra, and enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons [].Proteins containing this domain includes the related neurotrophic factor CDNF (cerebral dopamine neurotrophic factor) [].
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Protein Domain
IPR045332 | ARMET_N
Type: Domain
Description: This entry represents the N-terminal domain of ARMET.ARMET, also known as mesencephalic astrocyte-derived neurotrophic factor (MANF) or arginine-rich protein, is a small protein of approximately 170 residues which contains four di-sulphide bridges that are highly conserved from nematodes to humans. It is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress []. ARMET from Rattus norvegicus (Rat) selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra, and enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons [].Proteins containing this domain includes the related neurotrophic factor CDNF (cerebral dopamine neurotrophic factor) [].
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Protein Domain
IPR045333 | ARMET-like
Type: Family
Description: ARMET, also known as mesencephalic astrocyte-derived neurotrophic factor (MANF) or arginine-rich protein, is a small protein of approximately 170 residues which contains four di-sulphide bridges that are highly conserved from nematodes to humans. It is a soluble protein resident in the endoplasmic reticulum and induced by ER stress. It appears to be involved with dealing with mis-folded proteins in the ER, thus in quality control of ER stress []. ARMET from Rattus norvegicus (Rat) selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra, and enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons [].This entry also includes the related neurotrophic factor CDNF (cerebral dopamine neurotrophic factor) [].
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Protein
F7C1S6
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Protein
F6T4L3
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
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Protein
F6USD5
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
Q9CXI5
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
Q8CC36
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: false
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Protein
A8C1V1
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: true
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Protein
Q3TMX5
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
Q80ZP8
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: false
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