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Search results 101 to 115 out of 115 for Cep63

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0.016s
Type Details Score
DO Term
Protein Domain
Type: Domain
Description: This entry represents the N-terminal domain of the centrosomal proteins Cep63 and Deup1. Cep63 regulates mother-centriole-dependent centriole duplication, whereas Deup1 governs deuterosome assembly for large-scale de novo centriole biogenesis [].
Publication    
First Author: Kodani A
Year: 2015
Journal: Elife
Title: Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.
Volume: 4
Protein
Organism: Mus musculus/domesticus
Length: 601  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 536  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: true
Publication
First Author: Oshimori N
Year: 2009
Journal: EMBO J
Title: Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.
Volume: 28
Issue: 14
Pages: 2066-76
Protein Domain
Type: Family
Description: Cep72 is a centrosomal protein that interacts with Kizuna and plays an important role in maintaining microtubule-organizing activity and structural integrity of the centrosome. It is required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) []and for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization [].
Protein Domain
Type: Family
Description: Centriole amplification is controlled by two duplicated genes, Cep63 (centrosomal protein of 63kDa) and Deup1 (Deuterosome assembly protein 1).Cep63 regulates mother-centriole-dependent centriole duplication, whereas Deup1 is involved in large-scale de novo centriole biogenesis. Deup1, previously known as coiled-coil domain-containing protein 67, is a structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deup1 binds to Cep152 and then recruits Plk4 to activate centriole biogenesis [].
Publication  
First Author: Watanabe Y
Year: 2016
Journal: Nat Commun
Title: Autophagy controls centrosome number by degrading Cep63.
Volume: 7
Pages: 13508
Protein
Organism: Mus musculus/domesticus
Length: 646  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 470  
Fragment?: true