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Search results 101 to 182 out of 182 for Cers2

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Type Details Score
Publication
31971349 | J:329349
First Author: Alatibi KI
Year: 2020
Journal: FEBS J
Title: Sex-specific perturbation of complex lipids in response to medium-chain fatty acids in very long-chain acyl-CoA dehydrogenase deficiency.
Volume: 287
Issue: 16
Pages: 3511-3525
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Publication
28369476 | J:242353
First Author: Pichery M
Year: 2017
Journal: Hum Mol Genet
Title: PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Volume: 26
Issue: 10
Pages: 1787-1800
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Publication
38485951 | J:346053
First Author: Zhang J
Year: 2024
Journal: Nat Commun
Title: Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.
Volume: 15
Issue: 1
Pages: 2315
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Publication
23096701 | J:196477
First Author: Wang Z
Year: 2013
Journal: J Invest Dermatol
Title: Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.
Volume: 133
Issue: 3
Pages: 668-76
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Publication
25269881 | J:216600
First Author: Lau CG
Year: 2014
Journal: Mol Reprod Dev
Title: Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.
Volume: 81
Issue: 11
Pages: 994-1008
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Publication
29044125 | J:255485
First Author: Li S
Year: 2017
Journal: Sci Rep
Title: Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.
Volume: 7
Issue: 1
Pages: 13427
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Strain
MGI:5496704 | B6;129S4-Cers2<Gt(S16-4B1)Sor>/Cnrm
Attribute String: mutant stock, gene trap
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Allele
Cers2<tm1.1Kwi> | MGI:7621218
Name: ceramide synthase 2; targeted mutation 1.1, Klaus Willecke
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Cers2<tm2.1Kwi> | MGI:7621219
Name: ceramide synthase 2; targeted mutation 2.1, Klaus Willecke
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Cers2<tm1Kwi> | MGI:7621226
Name: ceramide synthase 2; targeted mutation 1, Klaus Willecke
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Cers2<tm1.2Kwi> | MGI:7621227
Name: ceramide synthase 2; targeted mutation 1.2, Klaus Willecke
Allele Type: Targeted
Attribute String: Reporter
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Allele
Cers2<tm2Kwi> | MGI:7621228
Name: ceramide synthase 2; targeted mutation 2, Klaus Willecke
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Cers2<tm2.2Kwi> | MGI:7621229
Name: ceramide synthase 2; targeted mutation 2.2, Klaus Willecke
Allele Type: Targeted
Attribute String: Reporter
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Publication
25213553 | -
First Author: Fan SH
Year: 2015
Journal: J Cell Biochem
Title: CERS2 suppresses tumor cell invasion and is associated with decreased V-ATPase and MMP-2/MMP-9 activities in breast cancer.
Volume: 116
Issue: 4
Pages: 502-13
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Protein
Q924Z4
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Publication
12105227 | -
First Author: Venkataraman K
Year: 2002
Journal: J Biol Chem
Title: Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells.
Volume: 277
Issue: 38
Pages: 35642-9
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Protein
H3BKZ9
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
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Publication
10198056 | -
First Author: Barz WP
Year: 1999
Journal: Mol Biol Cell
Title: Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins.
Volume: 10
Issue: 4
Pages: 1043-59
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Publication
15692566 | -
First Author: Vallée B
Year: 2005
Journal: EMBO J
Title: Lip1p: a novel subunit of acyl-CoA ceramide synthase.
Volume: 24
Issue: 4
Pages: 730-41
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Publication
15236759 | -
First Author: Jiang JC
Year: 2004
Journal: Exp Gerontol
Title: Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity.
Volume: 39
Issue: 7
Pages: 999-1009
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Publication
12445127 | -
First Author: Spassieva SD
Year: 2002
Journal: Plant J
Title: The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death.
Volume: 32
Issue: 4
Pages: 561-72
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Publication
26276842 | -
First Author: Luttgeharm KD
Year: 2015
Journal: Plant Physiol
Title: Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance.
Volume: 169
Issue: 2
Pages: 1108-17
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Protein Domain
IPR016439 | Lag1/Lac1-like
Type: Family
Description: Yeast ceramide synthase component Lag1 has a paralog, Lac1. This entry includes Lac1, Lag1 and their homologues from plants and animals [, , ], involved in sphingolipid synthesis.LAG1 and LAC1 contain multiple membrane-spanning domains and are localised to the endoplasmic reticulum (ER) []. They are essential subunits of the acyl-CoA-dependent ceramide synthase that is involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine [, , ].Human Lac1/Lag1 homologue CERS2 (ceramide synthase 2) is a tumour metastasis suppressor that can inhibit breast cancer cell invasion []. Tomato Lac1/Lag1 homologue ASC1 can mediate resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis [].Arabidopsis thaliana contains three ceramide synthases with distinct substrate specificities: LOH1 and LOH3 (LONGEVITY ASSURANCE GENE ONE HOMOLOG1 At3g25540 and 3 At1g19260) use very-long-chain fatty acyl-CoA and trihydroxy LCB substrates, and LOH2 (At3g19260) uses palmitoyl-CoA and dihydroxy LCB substrates [].
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Protein
H3BLB3
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: true
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Protein
Q3UK15
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Publication
11694577 | -
First Author: Schorling S
Year: 2001
Journal: Mol Biol Cell
Title: Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae.
Volume: 12
Issue: 11
Pages: 3417-27
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Publication
28320857 | J:242498
First Author: Ferreira NS
Year: 2017
Journal: J Biol Chem
Title: Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.
Volume: 292
Issue: 18
Pages: 7588-7597
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Publication
30251650 | J:270156
First Author: Edagawa M
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Widespread tissue distribution and synthetic pathway of polyunsaturated C24:2 sphingolipids in mammals.
Volume: 1863
Issue: 12
Pages: 1441-1448
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Publication
37466006 | J:339567
 
First Author: Qian X
Year: 2023
Journal: Dis Model Mech
Title: Ceramide compensation by ceramide synthases preserves retinal function and structure in a retinal dystrophy mouse model.
Volume: 16
Issue: 7
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Publication
22579584 | J:192993
First Author: Sassa T
Year: 2012
Journal: Biochim Biophys Acta
Title: A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells.
Volume: 1821
Issue: 7
Pages: 1031-7
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Publication
31766565 | J:283870
 
First Author: Sen NE
Year: 2019
Journal: Int J Mol Sci
Title: In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.
Volume: 20
Issue: 23
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Protein
Q9D6K9
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
Q8C172
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
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Protein
Q1A3B0
Organism: Mus musculus/domesticus
Length: 383  
Fragment?: false
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Protein
Q9D6J1
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
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Protein
H3BL08
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
D3YTM0
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
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Protein
H3BJ49
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
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Protein
D3Z0Z2
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: true
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Protein
H3BL50
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: false
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Protein
H3BJH5
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
D3Z4M2
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Protein
H3BJQ0
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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