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Search results 101 to 197 out of 197 for Chst4

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0.025s
Type Details Score
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752422
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267322
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1718522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283722
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Note: Expression was not detected in the endocrine system.
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1781522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1759722
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672722
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274122
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266022
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1624622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Image: ES403; Specimen S225
Note: Expression was weak in the digestive system.
Specimen Label: ES403; Specimen S225
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1646922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Image: ES403; Specimen S225
Specimen Label: ES403; Specimen S225
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1683322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Image: ES403; Specimen S225
Specimen Label: ES403; Specimen S225
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Image: ES403; Specimen S225
Specimen Label: ES403; Specimen S225
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5310207
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423531
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: ES403; Specimen S225
Detected: false
Specimen Num: 1
Publication
First Author: Hiraoka N
Year: 1999
Journal: Immunity
Title: A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34.
Volume: 11
Issue: 1
Pages: 79-89
Publication
First Author: Hiraoka N
Year: 2004
Journal: J Biol Chem
Title: Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing.
Volume: 279
Issue: 4
Pages: 3058-67
Publication
First Author: Uchimura K
Year: 2005
Journal: Nat Immunol
Title: A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules.
Volume: 6
Issue: 11
Pages: 1105-13
Publication
First Author: Lee JK
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue.
Volume: 263
Issue: 2
Pages: 543-9
Publication
First Author: Ito Z
Year: 2010
Journal: J Neurosci
Title: N-acetylglucosamine 6-O-sulfotransferase-1-deficient mice show better functional recovery after spinal cord injury.
Volume: 30
Issue: 17
Pages: 5937-47
Publication
First Author: Ohmichi Y
Year: 2011
Journal: J Exp Med
Title: Essential role of peripheral node addressin in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses.
Volume: 208
Issue: 5
Pages: 1015-25
Publication
First Author: Gauguet JM
Year: 2004
Journal: Blood
Title: Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes.
Volume: 104
Issue: 13
Pages: 4104-12
Publication
First Author: Patnode ML
Year: 2013
Journal: Glycobiology
Title: KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing.
Volume: 23
Issue: 3
Pages: 381-94
Publication
First Author: van Zante A
Year: 2003
Journal: J Exp Med
Title: Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouse.
Volume: 198
Issue: 9
Pages: 1289-300
Publication
First Author: Liu W
Year: 2023
Journal: Sci Rep
Title: A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses.
Volume: 13
Issue: 1
Pages: 15740
Publication
First Author: Narentuya
Year: 2019
Journal: Sci Rep
Title: GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain.
Volume: 9
Issue: 1
Pages: 4387
Publication
First Author: Hemmerich S
Year: 2001
Journal: Glycobiology
Title: Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.
Volume: 11
Issue: 1
Pages: 75-87
Publication
First Author: Kawashima H
Year: 2005
Journal: Nat Immunol
Title: N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules.
Volume: 6
Issue: 11
Pages: 1096-104
Publication
First Author: Anderson BE
Year: 2008
Journal: Blood
Title: Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells.
Volume: 111
Issue: 10
Pages: 5242-51
Publication
First Author: Hirakawa J
Year: 2010
Journal: J Biol Chem
Title: Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing.
Volume: 285
Issue: 52
Pages: 40864-78
Publication
First Author: Arata-Kawai H
Year: 2011
Journal: Am J Pathol
Title: Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.
Volume: 178
Issue: 1
Pages: 423-33
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: carbohydrate sulfotransferase 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase, Reporter
Allele
Name: transgene insertion 1, Hiroto Kawashima
Allele Type: Transgenic
Attribute String: Recombinase
Genotype
Symbol: Tg(Chst4-cre)1Hkwa/?
Background: involves: C3H/HeN * C57BL/6
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Tsuboi K
Year: 2013
Journal: J Immunol
Title: Role of high endothelial venule-expressed heparan sulfate in chemokine presentation and lymphocyte homing.
Volume: 191
Issue: 1
Pages: 448-55
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Chst4-cre)1Hkwa/?
Background: involves: 129S4/SvJaeSor * C3H/HeN * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Li X
Year: 2001
Journal: J Leukoc Biol
Title: CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin.
Volume: 69
Issue: 4
Pages: 565-74
Publication
First Author: Hermanns P
Year: 2008
Journal: Am J Hum Genet
Title: Congenital joint dislocations caused by carbohydrate sulfotransferase 3 deficiency in recessive Larsen syndrome and humero-spinal dysostosis.
Volume: 82
Issue: 6
Pages: 1368-74
Publication  
First Author: Liu NP
Year: 2000
Journal: Mol Vis
Title: Mutations in corneal carbohydrate sulfotransferase 6 gene (CHST6) cause macular corneal dystrophy in Iceland.
Volume: 6
Pages: 261-4
Protein Domain
Type: Family
Description: This entry represents carbohydrate sulphotransferase, which catalyses the transfer of a sulphate to position 6 of the galactose (Gal) residues in keratan. It may function in the sulphation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins and participate in the biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Carbohydrate sulphotransferase CHST1, CHST2, CHST3, and CHST4 are all involved in producing functional L-selectin ligands [].Deficiency of CHST3 (also known as chondroitin-6-sulphotransferase) has been associated with severe chondrodysplasia with progressive spinal involvement []. Macular corneal dystrophy (MCD) has also been shown to be caused by mutations in the carbohydrate sulphotransferase 6 gene (CHST6) [].
Publication
First Author: Tsuboi K
Year: 2015
Journal: J Biol Chem
Title: Autophagy Protects against Colitis by the Maintenance of Normal Gut Microflora and Secretion of Mucus.
Volume: 290
Issue: 33
Pages: 20511-26
Protein
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 472  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 471  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false