Type |
Details |
Score |
Protein Domain |
Type: |
Family |
Description: |
Testis-expressed protein 10 (TEX10) is a vertebrate protein and a component of the Five Friends of Methylated CHTOP (5FMC) [], PELP1 []and MLL1/MLL []complexes. Pre-rRNA-processing protein Ipi1 is found in fungi and is a component of the RIX1 complex, which is a critical determinant of DNA replication licensing []. |
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•
•
•
•
•
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Publication |
First Author: |
Takai H |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex. |
Volume: |
9 |
Issue: |
1 |
Pages: |
48-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huo L |
Year: |
2012 |
Journal: |
Cell Cycle |
Title: |
The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis. |
Volume: |
11 |
Issue: |
7 |
Pages: |
1325-39 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
273
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang Y |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
A Role of hIPI3 in DNA Replication Licensing in Human Cells. |
Volume: |
11 |
Issue: |
4 |
Pages: |
e0151803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamaki H |
Year: |
2009 |
Journal: |
Plant J |
Title: |
Identification of novel meristem factors involved in shoot regeneration through the analysis of temperature-sensitive mutants of Arabidopsis. |
Volume: |
57 |
Issue: |
6 |
Pages: |
1027-39 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of WD repeat-containing proteins, including Ipi3 from yeasts, WDR18 from animals and RID3 from Arabidopsis. Ipi3 is part of the Rix1 complex required for the processing of 35S pre-rRNA in pre-60S ribosomal particles and for the initiation of DNA replication []. It interacts with pre-RC proteins, binds chromatin predominantly at ARS sequences in a cell cycle-regulated and ORC- and Noc3-dependent manner []. WDR18, the human Ipi3 homologue, is a component of the Five Friends of Methylated CHTOP (5FMC) complex, which is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes []. It is also involved in human DNA replication licensing [, ]. RID3 acts as negative regulator of the CUC-STM pathway in shoot apical meristem (SAM) neo-formation []. |
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•
•
•
•
•
|
Publication |
First Author: |
Fanis P |
Year: |
2012 |
Journal: |
Mol Cell Proteomics |
Title: |
Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. |
Volume: |
11 |
Issue: |
11 |
Pages: |
1263-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finkbeiner E |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1067-78 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
928
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
338
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
431
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
332
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Dou Y |
Year: |
2005 |
Journal: |
Cell |
Title: |
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. |
Volume: |
121 |
Issue: |
6 |
Pages: |
873-85 |
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•
•
•
•
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