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Search results 101
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Clic1
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Type
Details
Score
Publication
First Author:
Mouse Genome Informatics Scientific Curators
Year:
2009
Journal:
Database Download
Title:
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
First Author:
Milton RH
Year:
2008
Journal:
J Neurosci
Title:
CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia.
Volume:
28
Issue:
45
Pages:
11488-99
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Publication
First Author:
Tulk BM
Year:
2002
Journal:
Am J Physiol Cell Physiol
Title:
CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel.
Volume:
282
Issue:
5
Pages:
C1103-12
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Publication
First Author:
Harrop SJ
Year:
2001
Journal:
J Biol Chem
Title:
Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
Volume:
276
Issue:
48
Pages:
44993-5000
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Publication
First Author:
Littler DR
Year:
2004
Journal:
J Biol Chem
Title:
The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition.
Volume:
279
Issue:
10
Pages:
9298-305
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Publication
First Author:
Warton K
Year:
2002
Journal:
J Biol Chem
Title:
Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1.
Volume:
277
Issue:
29
Pages:
26003-11
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Publication
First Author:
Valenzuela SM
Year:
2000
Journal:
J Physiol
Title:
The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle.
Volume:
529 Pt 3
Pages:
541-52
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Protein Domain
Type:
Family
Description:
Intracellular chloride ion channel proteins (CLICs) has been shown to exist in both soluble and integral membrane forms. Chloride intracellular channel protein 1 (CLIC1) can insert into membranes and form chloride ion channels []. Membrane insertion seems to be redox-regulated and may occur only under oxydising conditions []. Channel activity has been shown to have a strong pH dependence []. The soluble form of CLIC1 is monomeric and structurally homologous to the glutathione S-transferase superfamily, with a redox-active site resembling glutaredoxin [].CLIC-1 (also known as NCC27) is involved in regulation of the cell cycle [].
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Publication
First Author:
MartÃnez-Solano L
Year:
2009
Journal:
Proteomics
Title:
Proteomics of RAW 264.7 macrophages upon interaction with heat-inactivated Candida albicans cells unravel an anti-inflammatory response.
Volume:
9
Issue:
11
Pages:
2995-3010
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Publication
First Author:
Kleinjan ML
Year:
2023
Journal:
Arterioscler Thromb Vasc Biol
Title:
CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA.
Volume:
43
Issue:
8
Pages:
1441-1454
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Protein
Organism:
Mus musculus/domesticus
Length:
241
Fragment?:
false
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Protein
Organism:
Mus musculus/domesticus
Length:
241
Fragment?:
false
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Protein
Organism:
Mus musculus/domesticus
Length:
241
Fragment?:
false
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