Type |
Details |
Score |
Publication |
First Author: |
Yan Q |
Year: |
2017 |
Journal: |
Mol Pharmacol |
Title: |
Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death. |
Volume: |
92 |
Issue: |
6 |
Pages: |
640-652 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duncan PI |
Year: |
1997 |
Journal: |
Mol Cell Biol |
Title: |
In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase. |
Volume: |
17 |
Issue: |
10 |
Pages: |
5996-6001 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
242 |
Description: |
Phosphoserine; by CLK1 and CLK2 |
Type: |
modified residue |
End: |
242 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
243 |
Description: |
Phosphoserine; by CLK1 and CLK2 |
Type: |
modified residue |
End: |
243 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Dual specificity protein kinase CLK1 |
Type: |
chain |
End: |
483 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
483
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
135
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
The CLK family kinases, CLK1 and CLK2, phosphorylate and activate the tyrosine phosphatase, PTP-1B. |
|
•
•
•
•
•
|
Publication |
First Author: |
Colwill K |
Year: |
1996 |
Journal: |
EMBO J |
Title: |
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. |
Volume: |
15 |
Issue: |
2 |
Pages: |
265-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moeslein FM |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
The CLK family kinases, CLK1 and CLK2, phosphorylate and activate the tyrosine phosphatase, PTP-1B. |
Volume: |
274 |
Issue: |
38 |
Pages: |
26697-704 |
|
•
•
•
•
•
|
Publication |
First Author: |
Debdab M |
Year: |
2011 |
Journal: |
J Med Chem |
Title: |
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing. |
Volume: |
54 |
Issue: |
12 |
Pages: |
4172-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duncan PI |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Alternative splicing of STY, a nuclear dual specificity kinase. |
Volume: |
270 |
Issue: |
37 |
Pages: |
21524-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vajo Z |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1000-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kojima T |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Cloning of human PRP4 reveals interaction with Clk1. |
Volume: |
276 |
Issue: |
34 |
Pages: |
32247-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Villén J |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Large-scale phosphorylation analysis of mouse liver. |
Volume: |
104 |
Issue: |
5 |
Pages: |
1488-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
|
•
•
•
•
•
|