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Search results 101 to 169 out of 169 for Clstn1

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7573056
Assay Type: RNA in situ
Annotation Date: 2024-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1756326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7573095
Age: embryonic day 18.0
Specimen Label: 4A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4886187
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945105
Age: embryonic day 15.5
Image: g00560 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00560 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4886187
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945105
Age: postnatal day 7
Image: g00560 P7
Note: Expression was region specific and scattered.
Specimen Label: g00560 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7573056
Assay Type: RNA in situ
Annotation Date: 2024-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7573095
Age: embryonic day 18.0
Specimen Label: 4A
Detected: true
Specimen Num: 1
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Publication
- | J:67035
   
First Author: Vogt L
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for calsyntenin-1 protein
Pages: AJ289016
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Publication
12498782 | J:80943
First Author: Hintsch G
Year: 2002
Journal: Mol Cell Neurosci
Title: The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns.
Volume: 21
Issue: 3
Pages: 393-409
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Publication
20925061 | J:182473
First Author: Steuble M
Year: 2010
Journal: Proteomics
Title: Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles.
Volume: 10
Issue: 21
Pages: 3775-88
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Publication
21385839 | J:182978
First Author: Vagnoni A
Year: 2011
Journal: J Cell Sci
Title: Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.
Volume: 124
Issue: Pt 7
Pages: 1032-42
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Publication
23213470 | J:186387
First Author: Steuble M
Year: 2012
Journal: Biol Open
Title: Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport.
Volume: 1
Issue: 8
Pages: 761-74
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Publication
16760430 | J:113428
First Author: Konecna A
Year: 2006
Journal: Mol Biol Cell
Title: Calsyntenin-1 docks vesicular cargo to kinesin-1.
Volume: 17
Issue: 8
Pages: 3651-63
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Publication
11161476 | J:67326
First Author: Vogt L
Year: 2001
Journal: Mol Cell Neurosci
Title: Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain.
Volume: 17
Issue: 1
Pages: 151-66
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Publication
37585286 | J:342467
First Author: Shiraki Y
Year: 2023
Journal: Mol Biol Cell
Title: Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1.
Volume: 34
Issue: 11
Pages: ar110
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Publication
32467230 | J:297152
First Author: Gotoh N
Year: 2020
Journal: J Biol Chem
Title: Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice.
Volume: 295
Issue: 28
Pages: 9650-9662
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Publication
39122814 | J:353365
First Author: Honda K
Year: 2024
Journal: Sci Rep
Title: Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.
Volume: 14
Issue: 1
Pages: 18471
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Publication
21083616 | J:167050
First Author: Khan QE
Year: 2010
Journal: Eur J Oral Sci
Title: Expression of prion gene and presence of prion protein during development of mouse molar tooth germ.
Volume: 118
Issue: 6
Pages: 559-65
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Publication
30902970 | J:276486
First Author: Dinamarca MC
Year: 2019
Journal: Nat Commun
Title: Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.
Volume: 10
Issue: 1
Pages: 1331
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Publication
15172686 | J:92208
First Author: Takasato M
Year: 2004
Journal: Mech Dev
Title: Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.
Volume: 121
Issue: 6
Pages: 547-57
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Publication
24613359 | J:211830
First Author: Um JW
Year: 2014
Journal: Cell Rep
Title: Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Volume: 6
Issue: 6
Pages: 1096-1109
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Publication
28558017 | J:245526
First Author: Bibollet-Bahena O
Year: 2017
Journal: PLoS One
Title: A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.
Volume: 12
Issue: 5
Pages: e0177977
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
A0A0N4SW90
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein Domain
IPR026914 | Calsyntenin
Type: Family
Description: This family includes calsyntenin 1/2/3 (also known as alcadein-alpha/beta/gamma). They are single-pass type I membrane proteins that may modulate calcium-mediated postsynaptic signals [].CLSTN (also known as Alc) forms a tripartite complex with APP (amyloid beta-protein precursor) and X11L (a neuron-specific adaptor protein) in brain; this complex stabilizes both APP and CLSTN proteins metabolically. Deficiencies in the X11L-mediated interaction between CLSTN and APP and/or CTFbeta enhances the production of amyloid beta-protein and have been linked to the development or progression of Alzheimer's disease []. Moreover, CLSTN1 strongly associates with kinesin-1 light chains (KLC1) and acts as a cargo that regulates kinesin-1 function. It may affect the transport of APP-containing vesicles by kinesin-1 [].
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Publication
12972431 | -
First Author: Araki Y
Year: 2003
Journal: J Biol Chem
Title: Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.
Volume: 278
Issue: 49
Pages: 49448-58
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Protein
A0A4P8DYG6
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: false
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Protein Domain
IPR045588 | CLSTN_C
Type: Domain
Description: This entry represents the cytoplasmic C-terminal domain of calsyntenin (CLSTN) proteins 1, 2 and 3 (also known as alcadein-alpha, beta and gamma). These are postsynaptic Ca2-binding proteins, evolutionarily conserved type I membrane proteins. CLSTN (also known as Alc) forms a tripartite complex with APP (amyloid beta-protein precursor) and X11L (a neuron-specific adaptor protein) in brain; this complex stabilizes both APP and CLSTN proteins metabolically. Deficiencies in the X11L-mediated interaction between CLSTN and APP and/or CTFbeta enhances the production of amyloid beta-protein and have been linked to the development or progression of Alzheimer's disease []. Moreover, CLSTN1 strongly associates with kinesin-1 light chains (KLC1) and acts as a cargo that regulates kinesin-1 function. It may affect the transport of APP-containing vesicles by kinesin-1 []. This domain includes the WD motifs required for KLC1 interaction (although one WD motif is sufficient), and the NP motif [].
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Publication
31680833 | J:291923
 
First Author: Cheng K
Year: 2019
Journal: Front Neurosci
Title: Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome.
Volume: 13
Pages: 1098
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Protein
Q99JH7
Organism: Mus musculus/domesticus
Length: 956  
Fragment?: false
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Protein
Q9ER65
Organism: Mus musculus/domesticus
Length: 966  
Fragment?: false
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Protein
Q9EPL2
Organism: Mus musculus/domesticus
Length: 979  
Fragment?: false
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Protein
D3Z601
Organism: Mus musculus/domesticus
Length: 919  
Fragment?: false
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