Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:7711137 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711359 |
Age: |
postnatal day 21 |
Image: |
6F Ctcf Nkx-Cre |
Note: |
Significantly reduced number of positive cells compared with controls. |
Specimen Label: |
6F Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711139 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711373 |
Age: |
postnatal day 21 |
Image: |
6D Ctcf Nkx-Cre |
Note: |
Significantly reduced number of positive cells compared with controls. |
Specimen Label: |
6D Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711136 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711376 |
Age: |
postnatal day 21 |
Image: |
7G Ctcf Nkx-Cre |
Note: |
Similar as in the control. |
Specimen Label: |
7G Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711149 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711378 |
Age: |
postnatal day 21 |
Image: |
7K Ctcf Nkx-Cre |
Note: |
Similar as in the control. |
Specimen Label: |
7K Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711144 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711375 |
Age: |
postnatal day 21 |
Image: |
7A Ctcf Nkx-Cre |
Note: |
The total number (Gad1+) was not significantly different compared with the control. |
Specimen Label: |
7A Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711138 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711374 |
Age: |
postnatal day 21 |
Image: |
7D Ctcf Nkx-Cre |
Note: |
There was no difference in the number of positive interneurons, although tended to occupy upper cortical layers at the expense of deeper ones compared with the control. |
Specimen Label: |
7D Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711145 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7711377 |
Age: |
postnatal day 21 |
Image: |
7I Ctcf Nkx-Cre |
Note: |
Similar as in the control. |
Specimen Label: |
7I Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711137 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:7711359 |
Age: |
embryonic day 13.5 |
Image: |
2C Ctcf Nes-Cre |
Note: |
Fewer positive cells migrating tangentially from the medial ganglionic eminence toward the cortex in the mutant compared with control embryos. |
Specimen Label: |
2C Ctcf Nes-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711137 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:7711359 |
Age: |
embryonic day 13.5 |
Image: |
2E Ctcf Nes-Cre;Puma-/- |
Note: |
Fewer positive cells migrating tangentially from the medial ganglionic eminence toward the cortex in the mutant compared with control embryos. Preventing apoptosis of cells via removal of PUMA/Bbc3 failed to rescue the change. |
Specimen Label: |
2E Ctcf Nes-Cre;Puma-/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711143 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691021 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7711364 |
Age: |
embryonic day 13.5 |
Image: |
3C Ctcf Nes-Cre |
Note: |
Increased expression compared with the control. |
Specimen Label: |
3C Ctcf Nes-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711137 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691021 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:7711359 |
Age: |
embryonic day 13.5 |
Image: |
5D Ctcf Nkx-Cre |
Note: |
Fewer positive cells migrating tangentially from the medial ganglionic eminence toward the cortex in the mutant compared with control embryos. |
Specimen Label: |
5D Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 10.5 |
Image: |
S1F Ctcf fl/fl (upper) |
|
Specimen Label: |
S1F Ctcf fl/fl (upper) |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 10.5 |
Image: |
S1F Ctcf fl/fl (lower) |
|
Specimen Label: |
S1F Ctcf fl/fl (lower) |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186613 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 8.5 |
Image: |
2B E8.5 Ctcf fl/fl |
|
Specimen Label: |
2B E8.5 Ctcf fl/fl |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 9.5 |
Image: |
2B E9.5 Ctcf fl/fl |
|
Specimen Label: |
2B E9.5 Ctcf fl/fl |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 10.5 |
Image: |
2B E10.5 Ctcf fl/fl |
|
Specimen Label: |
2B E10.5 Ctcf fl/fl |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 9.5 |
Image: |
S2A Ctcf fl/+; Tie2-cre |
|
Specimen Label: |
S2A Ctcf fl/+; Tie2-cre |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 9.5 |
Image: |
S2A Ctcf fl/fl; Tie2-cre |
|
Specimen Label: |
S2A Ctcf fl/fl; Tie2-cre |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 9.5 |
Image: |
S2B Ctcf fl/+; Tie2-cre |
|
Specimen Label: |
S2B Ctcf fl/+; Tie2-cre |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 9.5 |
Image: |
S2B Ctcf fl/fl; Tie2-cre |
|
Specimen Label: |
S2B Ctcf fl/fl; Tie2-cre |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2674976 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7624265 |
Age: |
embryonic day 9.5 |
Image: |
S2A Ctcf fl/+; Tie2-cre |
|
Specimen Label: |
S2A Ctcf fl/+; Tie2-cre |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2674976 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7624265 |
Age: |
embryonic day 9.5 |
Image: |
S2A Ctcf fl/fl; Tie2-cre |
|
Specimen Label: |
S2A Ctcf fl/fl; Tie2-cre |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3672817 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 10.5 |
Image: |
S1A Ctcf fl/fl |
|
Specimen Label: |
S1A Ctcf fl/fl |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3672817 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 10.5 |
Image: |
S1A Ctcf fl/fl; Tie2-cre |
|
Specimen Label: |
S1A Ctcf fl/fl; Tie2-cre |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711141 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7711342 |
Age: |
embryonic day 13.5 |
Image: |
2B Ctcf Nes-Cre |
Note: |
Decreased expression compared with the control. In a subset of embryos, the reduction in expression was restricted to the caudal region. |
Specimen Label: |
2B Ctcf Nes-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711141 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:7711342 |
Age: |
embryonic day 12.5 |
Image: |
2G Ctcf Nes-Cre rostral |
Note: |
A subtle decrease compared with control. |
Specimen Label: |
2G Ctcf Nes-Cre rostral |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711141 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:7711342 |
Age: |
embryonic day 12.5 |
Image: |
2G Ctcf Nes-Cre caudal |
Note: |
A subtle decrease compared with control. |
Specimen Label: |
2G Ctcf Nes-Cre caudal |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711141 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7711342 |
Age: |
embryonic day 13.5 |
Image: |
2D Ctcf Nes-Cre;Puma-/- |
Note: |
Decreased expression compared with the control. Preventing apoptosis of cells via removal of PUMA/Bbc3 failed to rescue the change. |
Specimen Label: |
2D Ctcf Nes-Cre;Puma-/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711140 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7711363 |
Age: |
embryonic day 13.5 |
Image: |
3B Ctcf Nes-Cre |
Note: |
Increased expression compared with the control. |
Specimen Label: |
3B Ctcf Nes-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711154 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7711366 |
Age: |
embryonic day 13.5 |
Image: |
4B Ctcf Nes-Cre |
Note: |
Similar as in the control, in expression levels or spatial expression. |
Specimen Label: |
4B Ctcf Nes-Cre |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7711141 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-08-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747121 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7711342 |
Age: |
embryonic day 13.5 |
Image: |
5C Ctcf Nkx-Cre |
Note: |
Decreased expression compared with the control. |
Specimen Label: |
5C Ctcf Nkx-Cre |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGill BE |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons. |
Volume: |
38 |
Issue: |
1 |
Pages: |
200-219 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ling JQ |
Year: |
2006 |
Journal: |
Science |
Title: |
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. |
Volume: |
312 |
Issue: |
5771 |
Pages: |
269-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bergström R |
Year: |
2007 |
Journal: |
Cell Cycle |
Title: |
CTCF regulates asynchronous replication of the imprinted H19/Igf2 domain. |
Volume: |
6 |
Issue: |
4 |
Pages: |
450-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
MacPherson MJ |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
The CTCF insulator protein is posttranslationally modified by SUMO. |
Volume: |
29 |
Issue: |
3 |
Pages: |
714-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ideraabdullah FY |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
Novel cis-regulatory function in ICR-mediated imprinted repression of H19. |
Volume: |
355 |
Issue: |
2 |
Pages: |
349-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo Y |
Year: |
2022 |
Journal: |
Mol Cell |
Title: |
Chromatin jets define the properties of cohesin-driven in vivo loop extrusion. |
Volume: |
82 |
Issue: |
20 |
Pages: |
3769-3780.e5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 10.5 |
Image: |
S1F Ctcf fl/fl; Tie2-Cre (upper) |
Note: |
Authors report an overall normal vasculature pattern. |
Specimen Label: |
S1F Ctcf fl/fl; Tie2-Cre (upper) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 10.5 |
Image: |
S1F Ctcf fl/fl; Tie2-Cre (lower) |
Note: |
Authors report an overall normal vasculature pattern. |
Specimen Label: |
S1F Ctcf fl/fl; Tie2-Cre (lower) |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3661015 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 9.5 |
Image: |
1C E9.5 Ctcf fl/fl Right |
|
Specimen Label: |
1C E9.5 Ctcf fl/fl Right |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3661015 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 9.5 |
Image: |
1C E9.5 Ctcf fl/fl Left |
|
Specimen Label: |
1C E9.5 Ctcf fl/fl Left |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3661017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 10.5 |
Image: |
1C E10.5 Ctcf fl/fl Right |
|
Specimen Label: |
1C E10.5 Ctcf fl/fl Right |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3661017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624267 |
Age: |
embryonic day 10.5 |
Image: |
1C E10.5 Ctcf fl/fl Left |
|
Specimen Label: |
1C E10.5 Ctcf fl/fl Left |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186613 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 8.5 |
Image: |
2B E8.5 Ctcf fl/fl; Tie2-cre |
Note: |
Blood vessel area, vessel length and lacunarity comparable to control. |
Specimen Label: |
2B E8.5 Ctcf fl/fl; Tie2-cre |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 9.5 |
Image: |
2B E9.5 Ctcf fl/fl; Tie2-cre |
Note: |
Blood vessel area and length decreased, and lacunarity increased, compared to control. |
Specimen Label: |
2B E9.5 Ctcf fl/fl; Tie2-cre |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1328239 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-04-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3186617 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7624263 |
Age: |
embryonic day 10.5 |
Image: |
2B E10.5 Ctcf fl/fl; Tie2-cre |
Note: |
Blood vessel area and length decreased, and lacunarity increased, compared to control. |
Specimen Label: |
2B E10.5 Ctcf fl/fl; Tie2-cre |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee DH |
Year: |
2010 |
Journal: |
PLoS Genet |
Title: |
CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-Igf2 imprinting control region in prospermatogonia. |
Volume: |
6 |
Issue: |
11 |
Pages: |
e1001224 |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
|
|
|
|
Notes: |
CTCF binding |
Curation Status: |
Not curated (Different assay type) |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
|
|
|
|
Notes: |
CTCF binding |
Curation Status: |
Not curated (Different assay type) |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
|
|
|
|
Notes: |
CTCF binding |
Curation Status: |
Not curated (Different assay type) |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
|
|
|
|
Notes: |
CTCF binding |
Curation Status: |
Not curated (Different assay type) |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
|
|
|
|
Notes: |
CTCF binding |
Curation Status: |
Not curated (Different assay type) |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
|
|
|
|
Notes: |
CTCF binding |
Curation Status: |
Not curated (Different assay type) |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo C |
Year: |
2011 |
Journal: |
Nature |
Title: |
CTCF-binding elements mediate control of V(D)J recombination. |
Volume: |
477 |
Issue: |
7365 |
Pages: |
424-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu C |
Year: |
2024 |
Journal: |
Immunity |
Title: |
A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification. |
Volume: |
57 |
Issue: |
5 |
Pages: |
1005-1018.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Loukinov DI |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. |
Volume: |
99 |
Issue: |
10 |
Pages: |
6806-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair. |
Volume: |
11 |
Issue: |
1 |
Pages: |
4133 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barutcu AR |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus. |
Volume: |
9 |
Issue: |
1 |
Pages: |
1444 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kung JT |
Year: |
2015 |
Journal: |
Mol Cell |
Title: |
Locus-specific targeting to the X chromosome revealed by the RNA interactome of CTCF. |
Volume: |
57 |
Issue: |
2 |
Pages: |
361-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Narendra V |
Year: |
2016 |
Journal: |
Genes Dev |
Title: |
CTCF-mediated topological boundaries during development foster appropriate gene regulation. |
Volume: |
30 |
Issue: |
24 |
Pages: |
2657-2662 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanssen LLP |
Year: |
2017 |
Journal: |
Nat Cell Biol |
Title: |
Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo. |
Volume: |
19 |
Issue: |
8 |
Pages: |
952-961 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren G |
Year: |
2017 |
Journal: |
Mol Cell |
Title: |
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression. |
Volume: |
67 |
Issue: |
6 |
Pages: |
1049-1058.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung YH |
Year: |
2019 |
Journal: |
Mol Cell |
Title: |
Maintenance of CTCF- and Transcription Factor-Mediated Interactions from the Gametes to the Early Mouse Embryo. |
Volume: |
75 |
Issue: |
1 |
Pages: |
154-171.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun S |
Year: |
2013 |
Journal: |
Cell |
Title: |
Jpx RNA activates Xist by evicting CTCF. |
Volume: |
153 |
Issue: |
7 |
Pages: |
1537-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Q |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function. |
Volume: |
12 |
Issue: |
1 |
Pages: |
43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoon B |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. |
Volume: |
25 |
Issue: |
24 |
Pages: |
11184-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ortabozkoyun H |
Year: |
2022 |
Journal: |
Nat Genet |
Title: |
CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters. |
Volume: |
54 |
Issue: |
2 |
Pages: |
202-212 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Transcriptional repressor CTCF |
Type: |
chain |
End: |
736 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isbel L |
Year: |
2016 |
Journal: |
Elife |
Title: |
Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mikkelsen TS |
Year: |
2010 |
Journal: |
Cell |
Title: |
Comparative epigenomic analysis of murine and human adipogenesis. |
Volume: |
143 |
Issue: |
1 |
Pages: |
156-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ribeiro de Almeida C |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Critical role for the transcription regulator CCCTC-binding factor in the control of Th2 cytokine expression. |
Volume: |
182 |
Issue: |
2 |
Pages: |
999-1010 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim TG |
Year: |
2015 |
Journal: |
J Allergy Clin Immunol |
Title: |
CCCTC-binding factor controls the homeostatic maintenance and migration of Langerhans cells. |
Volume: |
136 |
Issue: |
3 |
Pages: |
713-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee DP |
Year: |
2019 |
Journal: |
Circulation |
Title: |
Robust CTCF-Based Chromatin Architecture Underpins Epigenetic Changes in the Heart Failure Stress-Gene Response. |
Volume: |
139 |
Issue: |
16 |
Pages: |
1937-1956 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim TG |
Year: |
2017 |
Journal: |
Exp Mol Med |
Title: |
CCCTC-binding factor is essential to the maintenance and quiescence of hematopoietic stem cells in mice. |
Volume: |
49 |
Issue: |
8 |
Pages: |
e371 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishihara K |
Year: |
2002 |
Journal: |
Hum Mol Genet |
Title: |
An evolutionarily conserved putative insulator element near the 3' boundary of the imprinted Igf2/H19 domain. |
Volume: |
11 |
Issue: |
14 |
Pages: |
1627-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magdinier F |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Both CTCF-dependent and -independent insulators are found between the mouse T cell receptor alpha and Dad1 genes. |
Volume: |
279 |
Issue: |
24 |
Pages: |
25381-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu D |
Year: |
2006 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Effect of CTCF-binding motif on regulation of PAX6 transcription. |
Volume: |
47 |
Issue: |
6 |
Pages: |
2422-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang M |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation. |
Volume: |
108 |
Issue: |
37 |
Pages: |
15231-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pham D |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf. |
Volume: |
29 |
Issue: |
5 |
Pages: |
1203-1220.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stadhouders R |
Year: |
2012 |
Journal: |
EMBO J |
Title: |
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. |
Volume: |
31 |
Issue: |
4 |
Pages: |
986-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sekimata M |
Year: |
2009 |
Journal: |
Immunity |
Title: |
CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. |
Volume: |
31 |
Issue: |
4 |
Pages: |
551-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosa-Garrido M |
Year: |
2017 |
Journal: |
Circulation |
Title: |
High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure. |
Volume: |
136 |
Issue: |
17 |
Pages: |
1613-1625 |
|
•
•
•
•
•
|
Publication |
First Author: |
Defossez PA |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso. |
Volume: |
280 |
Issue: |
52 |
Pages: |
43017-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Majumder P |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
B cell differentiation is associated with reprogramming the CCCTC binding factor-dependent chromatin architecture of the murine MHC class II locus. |
Volume: |
192 |
Issue: |
8 |
Pages: |
3925-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Monte E |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. |
Volume: |
291 |
Issue: |
30 |
Pages: |
15428-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim S |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Remote Memory and Cortical Synaptic Plasticity Require Neuronal CCCTC-Binding Factor (CTCF). |
Volume: |
38 |
Issue: |
22 |
Pages: |
5042-5052 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andreu MJ |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF. |
Volume: |
41 |
Issue: |
3 |
Pages: |
111501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shih HY |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. |
Volume: |
109 |
Issue: |
50 |
Pages: |
E3493-502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Follows GA |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Mapping and functional characterisation of a CTCF-dependent insulator element at the 3' border of the murine Scl transcriptional domain. |
Volume: |
7 |
Issue: |
3 |
Pages: |
e31484 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kopp ND |
Year: |
2020 |
Journal: |
Hum Mol Genet |
Title: |
Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. |
Volume: |
29 |
Issue: |
9 |
Pages: |
1498-1519 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Epidermal growth factor (EGF)-induced corneal epithelial wound healing through nuclear factor κB subtype-regulated CCCTC binding factor (CTCF) activation. |
Volume: |
288 |
Issue: |
34 |
Pages: |
24363-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Weerd JH |
Year: |
2014 |
Journal: |
Circ Res |
Title: |
A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system. |
Volume: |
115 |
Issue: |
4 |
Pages: |
432-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang J |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Nicotinamide adenine dinucleotide (NAD)-regulated DNA methylation alters CCCTC-binding factor (CTCF)/cohesin binding and transcription at the BDNF locus. |
Volume: |
107 |
Issue: |
50 |
Pages: |
21836-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Degner SC |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. |
Volume: |
108 |
Issue: |
23 |
Pages: |
9566-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Y |
Year: |
2023 |
Journal: |
Cell Death Differ |
Title: |
Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf. |
Volume: |
30 |
Issue: |
10 |
Pages: |
2293-2308 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy AR |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells. |
Volume: |
293 |
Issue: |
22 |
Pages: |
8449-8461 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
Long-Range Chromosome Interactions Mediated by Cohesin Shape Circadian Gene Expression. |
Volume: |
12 |
Issue: |
5 |
Pages: |
e1005992 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
272
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Faure AJ |
Year: |
2012 |
Journal: |
Genome Res |
Title: |
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules. |
Volume: |
22 |
Issue: |
11 |
Pages: |
2163-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ye A |
Year: |
2016 |
Journal: |
Epigenetics |
Title: |
PEG3 binds to H19-ICR as a transcriptional repressor. |
Volume: |
11 |
Issue: |
12 |
Pages: |
889-900 |
|
•
•
•
•
•
|