| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3527627 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
3D,E |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3527628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3527628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
4B |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3527628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
4C,D |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
3C |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
3D,E |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
4B |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3822153 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
4C,D |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7520892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7521973 |
| Age: |
postnatal week 10 |
|
|
| Specimen Label: |
1E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7520892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3540828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7521973 |
| Age: |
postnatal week 10 |
|
| Note: |
Expression highly co-localized with Gfap-positive astrocytes. |
| Specimen Label: |
1F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267924 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:3822153 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
3A,B |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7520892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3541028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7521973 |
| Age: |
postnatal week 10 |
|
|
| Specimen Label: |
1E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7520892 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3541028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7521973 |
| Age: |
postnatal week 10 |
|
| Note: |
Expression highly co-localized with Gfap-positive astrocytes. |
| Specimen Label: |
1F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4818657 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-08-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689420 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4818660 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
2a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4818657 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-08-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4818660 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
2b |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4818657 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-08-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689424 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:4818660 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
2c |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3822137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-05 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1609822 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:3822153 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression was strong in the facial mesoderm. |
| Specimen Label: |
2G,H |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:978886 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824153 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000633_08 |
|
| Specimen Label: |
euxassay_000633_08 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:978886 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824153 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000633_11 |
|
| Specimen Label: |
euxassay_000633_11 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:978886 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824153 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000633_12 |
|
| Specimen Label: |
euxassay_000633_12 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:978886 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824153 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000633_16 |
|
| Specimen Label: |
euxassay_000633_16 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:978886 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824153 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000633_18 |
|
| Specimen Label: |
euxassay_000633_18 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:978886 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824153 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000633_19 |
|
| Specimen Label: |
euxassay_000633_19 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
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Kumar V |
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2013 |
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Science |
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•
•
•
•
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Wellcome Trust Sanger Institute |
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2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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•
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| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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| First Author: |
Hansen GM |
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2008 |
| Journal: |
Genome Res |
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
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10 |
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1670-9 |
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
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| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
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| Title: |
MGI Sequence Curation Reference |
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•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
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•
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| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
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•
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| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
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| Title: |
Nomenclature Committee Use |
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•
•
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| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
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| First Author: |
GemPharmatech |
| Year: |
2020 |
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| Title: |
GemPharmatech Website. |
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| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
•
•
•
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| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
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| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
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| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
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| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
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| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
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•
•
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| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
•
•
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| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
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•
•
•
•
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| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
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•
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
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•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
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| Title: |
Annotation inferences using phylogenetic trees |
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•
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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•
•
•
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| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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•
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•
•
•
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| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
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•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
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| Publication |
| First Author: |
Nebel RA |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
e0148039 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Silva JM |
| Year: |
2009 |
| Journal: |
Cell |
| Title: |
Cyfip1 is a putative invasion suppressor in epithelial cancers. |
| Volume: |
137 |
| Issue: |
6 |
| Pages: |
1047-61 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
265
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
948
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
229
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
182
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bogdan S |
| Year: |
2004 |
| Journal: |
Development |
| Title: |
Sra-1 interacts with Kette and Wasp and is required for neuronal and bristle development in Drosophila. |
| Volume: |
131 |
| Issue: |
16 |
| Pages: |
3981-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Basu D |
| Year: |
2004 |
| Journal: |
Development |
| Title: |
Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development. |
| Volume: |
131 |
| Issue: |
17 |
| Pages: |
4345-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tiwari SS |
| Year: |
2016 |
| Journal: |
Brain |
| Title: |
Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss. |
| Volume: |
139 |
| Issue: |
Pt 10 |
| Pages: |
2751-2765 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry includes cytoplasmic fragile X messenger ribonucleoprotein 1-interacting proteins from humans and their homologues, such as Sra-1 (specifically Rac1-associated protein 1) from Drosophila and PIROGI from Arabidopsis. In humans, there are two members, CYFIP1 and CYFIP2. They both interact with FMRP (Fragile X messenger ribonucleoprotein 1), which is responsible for pathologic manifestations in the Fragile X Syndrome. CYFIP1 interacts with the small GTPase Rac1 [, ]. CYFIP1 represses cap-dependent translation of mRNA by interacting with the initiation factor eIF4E []. CYFIP1 and CYFIP2 are part of the Wiskott-Aldrich syndrome protein-family verprolin-homologous protein (WAVE) complex that regulates actin polymerization at synapses []. Drosophila Sra-1 interacts with the Kette and Wasp. It is required for neuronal and bristle development in Drosophila []. PIROGI is part of a WAVE complex that activates the ARP2/3 complex and is Involved in regulation of actin organization []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1253
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1253
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
451
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1251
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
969
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
894
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Santini E |
| Year: |
2017 |
| Journal: |
Sci Signal |
| Title: |
Reducing eIF4E-eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice. |
| Volume: |
10 |
| Issue: |
504 |
|
|
•
•
•
•
•
|