| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668514 |
| Pattern: |
Not Specified |
| Stage: |
TS14 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 9.0 |
| Image: |
2C |
|
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 14.5 |
| Image: |
3C |
|
| Specimen Label: |
3C |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668614 |
| Pattern: |
Not Specified |
| Stage: |
TS14 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 9.0 |
| Image: |
2C |
|
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618414 |
| Pattern: |
Regionally restricted |
| Stage: |
TS14 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 9.0 |
| Image: |
2C |
| Note: |
Expression is in the ventral domain of more mature somites, located centrally along the rostral/caudal axis. |
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618417 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 10.5 |
| Image: |
2F |
| Note: |
Expression is in maturing somites. |
| Specimen Label: |
2F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618417 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 10.5 |
| Image: |
2Q |
| Note: |
Expression is in the ventral domain of more mature somites, located centrally along the rostral/caudal axis. |
| Specimen Label: |
2Q |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 14.5 |
| Image: |
3C |
|
| Specimen Label: |
3C |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1609814 |
| Pattern: |
Not Specified |
| Stage: |
TS14 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 9.0 |
| Image: |
2C |
|
| Specimen Label: |
2C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2006-12-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1609814 |
| Pattern: |
Not Specified |
| Stage: |
TS14 |
| Assay Id: |
MGI:3691493 |
| Age: |
embryonic day 9.0 |
| Image: |
2P |
|
| Specimen Label: |
2P |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3691492 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-10-26 |
| Strength: |
Trace |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:5439650 |
| Age: |
postnatal |
|
| Note: |
Little or no expression in incisor pulp. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xue H |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Disruption of the Dapper3 gene aggravates ureteral obstruction-mediated renal fibrosis by amplifying Wnt/β-catenin signaling. |
| Volume: |
288 |
| Issue: |
21 |
| Pages: |
15006-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kivimäe S |
| Year: |
2011 |
| Journal: |
BMC Biochem |
| Title: |
All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. |
| Volume: |
12 |
|
| Pages: |
33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Youlten SE |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
2444 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ingham NJ |
| Year: |
2019 |
| Journal: |
PLoS Biol |
| Title: |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
| Volume: |
17 |
| Issue: |
4 |
| Pages: |
e3000194 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dickinson ME |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
High-throughput discovery of novel developmental phenotypes. |
| Volume: |
537 |
| Issue: |
7621 |
| Pages: |
508-514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
757
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
150
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Dact (dapper) proteins were identified through binding to dishevelled, a cytoplasmic protein central to Wnt signaling. The different dact proteins seem to have distinct signaling and developmental roles. In Zebrafish, dact1 but not dact2 is required to enhance Wnt/beta-catenin activity, while functional interaction with Wnt/Ca2+-PCP signaling has been described for dact2, but not dact1 []. Data from other vertebrates seems to be consistent with a distinct signaling and developmental role for dact1, dact2 and dact3 [].This entry represents dact2. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Dact (dapper) proteins were identified through binding to dishevelled, a cytoplasmic protein central to Wnt signaling. The different dact proteins seem to have distinct signaling and developmental roles. In Zebrafish, dact1 but not dact2 is required to enhance Wnt/beta-catenin activity, while functional interaction with Wnt/Ca2+-PCP signaling has been described for dact2, but not dact1 []. Data from other vertebrates seems to be consistent with a distinct signaling and developmental role for dact1, dact2 and dact3 []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Katoh M |
| Year: |
2005 |
| Journal: |
Int J Mol Med |
| Title: |
Identification and characterization of rat Dact1 and Dact2 genes in silico. |
| Volume: |
15 |
| Issue: |
6 |
| Pages: |
1045-9 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Dact (dapper) proteins were identified through binding to dishevelled, a cytoplasmic protein central to Wnt signaling. The different dact proteins seem to have distinct signaling and developmental roles. In Zebrafish, dact1 but not dact2 is required to enhance Wnt/beta-catenin activity, while functional interaction with Wnt/Ca2+-PCP signaling has been described for dact2, but not dact1 []. Data from other vertebrates seems to be consistent with a distinct signaling and developmental role for dact1, dact2 and dact3 [].This entry represents dact1. Dact1 is the orthologue of a protein known in Xenopus as dapper or frodo []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
778
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
778
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
815
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Costa Cruz PH |
| Year: |
2020 |
| Journal: |
RNA |
| Title: |
A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing. |
| Volume: |
26 |
| Issue: |
4 |
| Pages: |
454-469 |
|
•
•
•
•
•
|