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Search results 101 to 105 out of 105 for Dcaf1

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Type Details Score
Publication
First Author: Kim K
Year: 2013
Journal: Mol Cell
Title: VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.
Volume: 52
Issue: 3
Pages: 459-67
Protein Domain
Type: Family
Description: This entry represents the VPRBP/DCAF1 family, whose members include protein VPRBP from mammals [], protein mahjong form fruit flies []and DCAF1 from worms and plants []. They are the substrate recognition component of the E3 ubiquitin-protein ligase complex. Human VPRBP is part of the CUL4A-RBX1-DDB1-DCAF1/VPRBP complex that mediates ubiquitination and proteasome-dependent degradation of proteins []. VPRBP also has kinase activity and is capable of phosphorylating histone H2A on threonine 120 (H2AT120p) in a nucleosomal context [].
Publication  
First Author: Yu C
Year: 2015
Journal: Nat Commun
Title: CRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation.
Volume: 6
Pages: 8017
Publication
First Author: Angers S
Year: 2006
Journal: Nature
Title: Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Volume: 443
Issue: 7111
Pages: 590-3
Protein
Organism: Mus musculus/domesticus
Length: 1506  
Fragment?: false