Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
408
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
399
 |
Fragment?: |
false |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Protein DDI1 homolog 1 |
Type: |
chain |
End: |
408 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Protein DDI1 homolog 2 |
Type: |
chain |
End: |
399 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaplun L |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease. |
Volume: |
25 |
Issue: |
13 |
Pages: |
5355-62 |
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•
•
•
•
•
|
Publication |
First Author: |
Trempe JF |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family. |
Volume: |
6 |
|
Pages: |
33671 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Y |
Year: |
2001 |
Journal: |
Mol Genet Genomics |
Title: |
Two alternative cell cycle checkpoint pathways differentially control DNA damage-dependent induction of MAG1 and DDI1 expression in yeast. |
Volume: |
266 |
Issue: |
3 |
Pages: |
436-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lehrbach NJ |
Year: |
2016 |
Journal: |
Elife |
Title: |
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain is found in eukaryotic aspartyl protease DDI1 (DNA Damage Inducible protein 1; MEROPS identifier A28.001). The remarkable structural similarity between this central domain of DDI1 and the retroviral proteases suggests that DDI1 functions proteolytically during regulated protein turnover [, ]. DDI1 has been shown to activate an endoplasmic-reticulum isoform of the transcription factor SKN-1 in Caenorhabditis elegans when the proteasome is dysfunctional []. DDI1 also has an amino-terminal ubiquitin-like domain and/or a UBA (ubiquitin-associated) domain []. |
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•
•
•
•
•
|
Publication |
First Author: |
Bertolaet BL |
Year: |
2001 |
Journal: |
Nat Struct Biol |
Title: |
UBA domains of DNA damage-inducible proteins interact with ubiquitin. |
Volume: |
8 |
Issue: |
5 |
Pages: |
417-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertolaet BL |
Year: |
2001 |
Journal: |
J Mol Biol |
Title: |
UBA domains mediate protein-protein interactions between two DNA damage-inducible proteins. |
Volume: |
313 |
Issue: |
5 |
Pages: |
955-63 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
DDI1 (DNA damage inducible protein 1) has an amino-terminal ubiquitin-like domain, an retroviral protease-like (RVP-like) domain, and a UBA (ubiquitin-associated) domain. This entry represents the amino-terminal ubiquitin-like domain of DDI1 [, , ].Ubiquitin is a globular protein, the last four C-terminal residues (Leu-Arg-Gly-Gly) extending from the compact structure to form a 'tail', important for its function. The latter is mediatedby the covalent conjugation of ubiquitin to target proteins, by an isopeptide linkage between the C-terminal glycine and the epsilon amino group of lysine residues in the target proteins. |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
270
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
219
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
190
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
240
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
251
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sirkis R |
Year: |
2006 |
Journal: |
J Mol Biol |
Title: |
Ddi1, a eukaryotic protein with the retroviral protease fold. |
Volume: |
364 |
Issue: |
3 |
Pages: |
376-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Villén J |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Large-scale phosphorylation analysis of mouse liver. |
Volume: |
104 |
Issue: |
5 |
Pages: |
1488-93 |
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•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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•
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•
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