| Type |
Details |
Score |
| Publication |
| First Author: |
Jiang Y |
| Year: |
2017 |
| Journal: |
Protein Cell |
| Title: |
The emerging roles of the DDX41 protein in immunity and diseases. |
| Volume: |
8 |
| Issue: |
2 |
| Pages: |
83-89 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
DDX41 interacts with several spliceosomal proteins and may recognise the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response []. DDX41 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. Mutations of the DDX41 gene cause myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF) [].This entry represents the DEAD-box domain of DDX41. It contains the ATP-binding region []. |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Del(11Nmur2-Sparc)2Anjm/+ Del(11Sparc-Gpx3)91Anjm/+ |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Smim3/Smim3<+> Cd74/Cd74<+> Lmo2/Lmo2<+> |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cd74/Cd74<+> Lmo2/Lmo2<+> Smim3/Smim3<+> |
| Background: |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Smim3/Smim3<+> Cd74/Cd74<+> Lmo2/Lmo2<+> Trp53/Trp53 |
| Background: |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schütz P |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
Comparative structural analysis of human DEAD-box RNA helicases. |
| Volume: |
5 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
622
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
622
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
633
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Messaoud-Nacer Y |
| Year: |
2022 |
| Journal: |
Cell Death Dis |
| Title: |
STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS). |
| Volume: |
13 |
| Issue: |
3 |
| Pages: |
269 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Villén J |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Large-scale phosphorylation analysis of mouse liver. |
| Volume: |
104 |
| Issue: |
5 |
| Pages: |
1488-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huttlin EL |
| Year: |
2010 |
| Journal: |
Cell |
| Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
| Volume: |
143 |
| Issue: |
7 |
| Pages: |
1174-89 |
|
•
•
•
•
•
|