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Search results 101 to 155 out of 155 for Det1

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0.03s
Type Details Score
GXD Expression    
Probe: MGI:7356324
Assay Type: RNA in situ
Annotation Date: 2022-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7367204
Age: embryonic day 15.5
Specimen Label: Table 1 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7356324
Assay Type: RNA in situ
Annotation Date: 2022-10-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7367204
Age: embryonic day 15.5
Specimen Label: Table 1 Emx2<-/->
Detected: true
Specimen Num: 2
Allele    
Name: DET1 partner of COP1 E3 ubiquitin ligase; wild type
Allele  
Name: DET1 and DDB1 associated 1; gene trap OST218022, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap OST379387, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap RRY275, BayGenomics
Allele Type: Gene trapped
Allele
Name: DET1 and DDB1 associated 1; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele  
Name: DET1 and DDB1 associated 1; gene trap PST7386, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: DET1 partner of COP1 E3 ubiquitin ligase; gene trap D054C12, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap E031G06, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap E305B11, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: DET1 partner of COP1 E3 ubiquitin ligase; gene trap OST61773, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: DET1 partner of COP1 E3 ubiquitin ligase; gene trap OST149285, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: DET1 partner of COP1 E3 ubiquitin ligase; gene trap OST259573, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap PST8030, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap IST13375B10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: DET1 and DDB1 associated 1; gene trap Ayu21-KBW167, Institute of Molecular Embryology and Genetics
Allele Type: Gene trapped
Allele
Name: DET1 and DDB1 associated 1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: DET1 and DDB1 associated 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: DET1 and DDB1 associated 1; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: DET1 partner of COP1 E3 ubiquitin ligase; endonuclease-mediated mutation 16, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: DET1 partner of COP1 E3 ubiquitin ligase; endonuclease-mediated mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: DET1 and DDB1 associated 1; endonuclease-mediated mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: DET1 partner of COP1 E3 ubiquitin ligase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: DET1 partner of COP1 E3 ubiquitin ligase; targeted mutation 1, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: DET1 partner of COP1 E3 ubiquitin ligase; gene trap 505G1, Centre for Modeling Human Disease
Allele Type: Gene trapped
Strain
Attribute String: coisogenic
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Det1/Det1
Background: C57BL/6N-Det1/Bay
Zygosity: hm
Has Mutant Allele: true
Protein Domain
Type: Domain
Description: This entry represents the N-terminal domain of DDA1 (DET1- and DDB1-associated protein 1) ubiquitin ligase, which binds strongly with Det1 (De-etiolated 1) and DDB1 (Damaged DNA binding protein 1 associated 1). Together DDA1, DDB1 and Det1 form the DDD core complex, which recruits a specific UBE2E enzyme to form specific DDD-E2 complexes []. Component of the DDD-E2 complexes which may provide a platform for interaction with cul4a and WD repeat proteins. These proteins may be involved in ubiquitination and subsequent proteasomal degradation of target proteins.
Protein
Organism: Mus musculus/domesticus
Length: 37  
Fragment?: false
Publication
First Author: Irigoyen ML
Year: 2014
Journal: Plant Cell
Title: Targeted degradation of abscisic acid receptors is mediated by the ubiquitin ligase substrate adaptor DDA1 in Arabidopsis.
Volume: 26
Issue: 2
Pages: 712-28
Publication
First Author: Olma MH
Year: 2009
Journal: J Cell Sci
Title: An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.
Volume: 122
Issue: Pt 7
Pages: 1035-44
Protein Domain
Type: Family
Description: DDA1 is a core subunit of multiple Cul4-based E3 ligases (CRL4s), involved in ubiquitination and subsequent proteasomal degradation of target proteins, which regulate key developmental and stress responses in eukaryotes [, ]. In mammals, DDA1 binds to DET1 and DDB1 to form DDD complexes, which recruit specific ubiquitin-conjugating UBE2E enzymes to form DDD-E2 complexes []. The DDD-E2 complex provides a platform for interaction with Cul4A and beta-transducing (also called WD40) repeat proteins. DDA1 is conserved in higher eukaryotes, including Arabidopsis [].
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
Publication
First Author: Li H
Year: 2006
Journal: Mol Cell Neurosci
Title: Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.
Volume: 33
Issue: 2
Pages: 136-49
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Download
Title: MGI cDNA Clone Load
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112