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Search results 101 to 176 out of 176 for Diablo

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3762882
Assay Type: Immunohistochemistry
Annotation Date: 2007-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Spotted
Stage: TS02
Assay Id: MGI:3762887
Age: embryonic day 1.0
Note: Staining is in the mitochondrial area.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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Publication
15814844 | J:100749
First Author: Burri L
Year: 2005
Journal: Mol Biol Cell
Title: Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane.
Volume: 16
Issue: 6
Pages: 2926-33
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Publication
16239929 | J:126299
First Author: Hansen TM
Year: 2006
Journal: Cell Death Differ
Title: Smac/DIABLO is not released from mitochondria during apoptotic signalling in cells deficient in cytochrome c.
Volume: 13
Issue: 7
Pages: 1181-90
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Publication
15509788 | J:94227
First Author: Martins LM
Year: 2004
Journal: Mol Cell Biol
Title: Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice.
Volume: 24
Issue: 22
Pages: 9848-62
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Publication
15882989 | J:98322
First Author: Mendoza FJ
Year: 2005
Journal: Biochem Biophys Res Commun
Title: MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondria.
Volume: 331
Issue: 4
Pages: 1089-98
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Publication
21722859 | J:186803
First Author: Cheng J
Year: 2011
Journal: Am J Hum Genet
Title: Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64.
Volume: 89
Issue: 1
Pages: 56-66
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Publication
11604410 | J:182411
First Author: Verhagen AM
Year: 2002
Journal: J Biol Chem
Title: HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.
Volume: 277
Issue: 1
Pages: 445-54
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Publication
22751125 | J:198020
First Author: Qiu W
Year: 2013
Journal: Oncogene
Title: An apoptosis-independent role of SMAC in tumor suppression.
Volume: 32
Issue: 19
Pages: 2380-9
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Publication
15207275 | J:91241
First Author: Wang X
Year: 2004
Journal: Neurobiol Dis
Title: X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
Volume: 16
Issue: 1
Pages: 179-89
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Publication
21041628 | J:166608
First Author: Qiu W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
Volume: 107
Issue: 46
Pages: 20027-32
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Publication
17562856 | J:125016
First Author: Ho AT
Year: 2007
Journal: Mol Cell Biol
Title: XIAP activity dictates Apaf-1 dependency for caspase 9 activation.
Volume: 27
Issue: 16
Pages: 5673-85
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Publication
21454573 | J:172677
First Author: Kang BH
Year: 2011
Journal: J Biol Chem
Title: Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein.
Volume: 286
Issue: 19
Pages: 16758-67
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Publication
17218959 | J:139242
First Author: Vaughn AE
Year: 2007
Journal: Cell Death Differ
Title: Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons.
Volume: 14
Issue: 5
Pages: 973-81
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Publication
19875445 | J:161686
First Author: Owens TW
Year: 2010
Journal: J Biol Chem
Title: Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.
Volume: 285
Issue: 2
Pages: 1081-8
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Publication
25056906 | J:214844
First Author: Andree M
Year: 2014
Journal: EMBO J
Title: BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.
Volume: 33
Issue: 19
Pages: 2171-87
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Publication
12011074 | J:78039
First Author: Li S
Year: 2002
Journal: J Biol Chem
Title: Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis.
Volume: 277
Issue: 30
Pages: 26912-20
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Publication
14623868 | J:86711
First Author: Potts PR
Year: 2003
Journal: J Cell Biol
Title: Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.
Volume: 163
Issue: 4
Pages: 789-99
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Publication
29073098 | J:252907
First Author: Stewart K
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.
Volume: 114
Issue: 43
Pages: E9016-E9025
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Publication
17376863 | J:120125
First Author: Wiley SE
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.
Volume: 104
Issue: 13
Pages: 5318-23
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Publication
19060338 | J:147600
First Author: Ni HM
Year: 2009
Journal: J Biol Chem
Title: Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice.
Volume: 284
Issue: 7
Pages: 4373-82
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Publication
18309324 | J:180458
First Author: Galluzzi L
Year: 2008
Journal: Cell Death Differ
Title: No death without life: vital functions of apoptotic effectors.
Volume: 15
Issue: 7
Pages: 1113-23
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Publication
18385140 | J:137567
First Author: Rardin MJ
Year: 2008
Journal: J Biol Chem
Title: Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane.
Volume: 283
Issue: 22
Pages: 15440-50
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Publication
20614026 | J:161997
First Author: Hostager BS
Year: 2010
Journal: PLoS One
Title: HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.
Volume: 5
Issue: 6
Pages: e11380
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Publication
23055939 | J:193641
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
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Publication
37813816 | J:358134
First Author: Soma S
Year: 2024
Journal: Stem Cells
Title: O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation.
Volume: 42
Issue: 1
Pages: 55-63
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume: 16
Issue: 4
Pages: 968-984
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Publication
12819136 | J:84168
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 54
Description: Diablo IAP-binding mitochondrial protein
Type: chain
End: 237
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Publication
15178455 | -
First Author: Yoon K
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis.
Volume: 319
Issue: 2
Pages: 649-54
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DO Term
DOID:0110585 | autosomal dominant nonsyndromic deafness 64
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Publication
17336467 | -
First Author: Montesanti A
Year: 2007
Journal: Gene
Title: Cloning and characterization of Xenopus laevis Smac/DIABLO.
Volume: 392
Issue: 1-2
Pages: 187-95
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Protein Domain
IPR015142 | Smac_DIABLO
Type: Family
Description: This entry represents DIABLO (Direct IAP-Binding protein with Low PI) proteins, also known as Smac (Second Mitochondria-derived Activator of Caspases) and and their homologues. DIABLO promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway, and by opposing the inhibitory activity of inhibitor of apoptosis proteins (XIAP-BIR3). The protein assumes an elongated three-helix bundle structure, and forms a dimer in solution [, ].
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Protein
Q8R1D8
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
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Protein
Q3TEL3
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
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Protein
Q7TPS3
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Protein
D3Z3K5
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
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Protein
A0A0G2JGS0
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
D3Z2Q3
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
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Publication
11140638 | -
First Author: Wu G
Year: 2000
Journal: Nature
Title: Structural basis of IAP recognition by Smac/DIABLO.
Volume: 408
Issue: 6815
Pages: 1008-12
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Publication
10972280 | -
First Author: Chai J
Year: 2000
Journal: Nature
Title: Structural and biochemical basis of apoptotic activation by Smac/DIABLO.
Volume: 406
Issue: 6798
Pages: 855-62
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Protein Domain
IPR009062 | Smac/DIABLO-like_sf
Type: Homologous_superfamily
Description: Smac (Second Mitochondria-derived Activator of Caspase) and DIABLO (Direct IAP-Binding protein with Low PI) are 29kDa mitochondrial precursor proteins. Apoptosis, or programmed cell death, is an essential process in metazoan development and homeostasis. Apoptosis is carried out by caspases, which are under tight regulatory control. Inhibitor-of-apoptosis proteins (IAP) suppress apoptosis by inhibiting caspases, while the mitochondrial protein Smac/Diablo promotes apoptosis by suppressing IAPs. The N-terminal four sequences in Smac/Diablo are responsible for the protein's interaction with IAPs []. The crystal structure of Smac/Diablo reveals a closed, three-helical bundle structure with a left-handed twist, and that the protein homodimerises through an extensive hydrophobic interface [].
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Publication
16469770 | J:110069
First Author: Vera Y
Year: 2006
Journal: Mol Endocrinol
Title: Involvement of p38 mitogen-activated protein kinase and inducible nitric oxide synthase in apoptotic signaling of murine and human male germ cells after hormone deprivation.
Volume: 20
Issue: 7
Pages: 1597-609
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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