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Dnajb2
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0.019s
Type
Details
Score
Protein Domain
Type:
Family
Description:
DNAJB2 (also known as HSJ-1) contains an N-terminal J-domain and the C-terminal UIMs (ubiquitin (Ub)-interacting motifs)-containing domain. It binds and stimulates ATPase activity of HSP70 through its J-domain []. It also binds to polyUb chains through its UIM domain and contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins [, ].
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Publication
First Author:
Novoselov SS
Year:
2013
Journal:
PLoS One
Title:
Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Volume:
8
Issue:
8
Pages:
e73944
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Publication
First Author:
Labbadia J
Year:
2012
Journal:
Brain
Title:
Suppression of protein aggregation by chaperone modification of high molecular weight complexes.
Volume:
135
Issue:
Pt 4
Pages:
1180-96
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Protein
Organism:
Mus musculus/domesticus
Length:
110
Fragment?:
true
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Protein
Organism:
Mus musculus/domesticus
Length:
76
Fragment?:
true
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Protein
Organism:
Mus musculus/domesticus
Length:
324
Fragment?:
false
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