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Search results 101 to 200 out of 1714 for Dnmt3a

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Type Details Score
Publication
31703632 | J:290465
First Author: Shi X
Year: 2019
Journal: BMC Cancer
Title: Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study.
Volume: 19
Issue: 1
Pages: 1072
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Publication
11919202 | J:150927
First Author: Gowher H
Year: 2002
Journal: J Biol Chem
Title: Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases.
Volume: 277
Issue: 23
Pages: 20409-14
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Publication
33159179 | J:307150
First Author: Sportoletti P
Year: 2021
Journal: Leukemia
Title: Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice.
Volume: 35
Issue: 7
Pages: 1949-1963
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Publication
33846253 | J:313790
 
First Author: Chen DY
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Dnmt3a deficiency in the skin causes focal, canonical DNA hypomethylation and a cellular proliferation phenotype.
Volume: 118
Issue: 16
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Publication
12897133 | J:84782
First Author: Chen T
Year: 2003
Journal: Mol Cell Biol
Title: Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.
Volume: 23
Issue: 16
Pages: 5594-605
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Publication
28425913 | J:256852
   
First Author: Rinaldi L
Year: 2017
Journal: Elife
Title: Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ.
Volume: 6
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Publication
17477386 | J:121563
First Author: Nguyen S
Year: 2007
Journal: Dev Dyn
Title: Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan.
Volume: 236
Issue: 6
Pages: 1663-76
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Publication
30321403 | J:269535
First Author: Veland N
Year: 2019
Journal: Nucleic Acids Res
Title: DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells.
Volume: 47
Issue: 1
Pages: 152-167
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Publication
32222282 | J:305728
First Author: Sun W
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Virus-mediated Dnmt1 and Dnmt3a deletion disrupts excitatory synaptogenesis and synaptic function in primary cultured hippocampal neurons.
Volume: 526
Issue: 2
Pages: 361-367
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Publication
17713477 | J:245372
First Author: Jia D
Year: 2007
Journal: Nature
Title: Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
Volume: 449
Issue: 7159
Pages: 248-51
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Publication
27016502 | J:236830
First Author: Meyer SE
Year: 2016
Journal: Cancer Discov
Title: DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.
Volume: 6
Issue: 5
Pages: 501-15
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Publication
27865785 | J:314514
 
First Author: Singh RK
Year: 2017
Journal: Exp Eye Res
Title: Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina.
Volume: 159
Pages: 132-146
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Publication
29027601 | J:255612
First Author: Uysal F
Year: 2017
Journal: J Mol Histol
Title: DNMT1, DNMT3A and DNMT3B proteins are differently expressed in mouse oocytes and early embryos.
Volume: 48
Issue: 5-6
Pages: 417-426
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Publication
15672446 | J:97492
First Author: Feng J
Year: 2005
Journal: J Neurosci Res
Title: Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system.
Volume: 79
Issue: 6
Pages: 734-46
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Publication
17938196 | J:128981
First Author: Li JY
Year: 2007
Journal: Mol Cell Biol
Title: Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog.
Volume: 27
Issue: 24
Pages: 8748-59
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Publication
34048432 | J:306258
First Author: Kibe K
Year: 2021
Journal: PLoS Genet
Title: The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.
Volume: 17
Issue: 5
Pages: e1009570
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Publication
37527244 | J:349016
First Author: Uehara R
Year: 2023
Journal: PLoS Genet
Title: The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes.
Volume: 19
Issue: 8
Pages: e1010855
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Publication
16973295 | J:113145
First Author: Watanabe D
Year: 2006
Journal: Neuroscience
Title: Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development.
Volume: 142
Issue: 3
Pages: 727-37
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Publication
29146735 | J:259618
First Author: Hatazawa Y
Year: 2018
Journal: FASEB J
Title: Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration.
Volume: 32
Issue: 3
Pages: 1452-1467
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Publication
38627502 | J:347433
First Author: Kubo N
Year: 2024
Journal: Nat Commun
Title: Combined and differential roles of ADD domains of DNMT3A and DNMT3L on DNA methylation landscapes in mouse germ cells.
Volume: 15
Issue: 1
Pages: 3266
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Publication
16682412 | J:116430
First Author: Li H
Year: 2006
Journal: J Biol Chem
Title: The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.
Volume: 281
Issue: 28
Pages: 19489-500
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Publication
25801914 | J:224952
First Author: Chang YI
Year: 2015
Journal: Leukemia
Title: Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
Volume: 29
Issue: 9
Pages: 1847-56
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Publication
26059604 | J:229113
First Author: Manoharan A
Year: 2015
Journal: Eur J Immunol
Title: De novo DNA Methyltransferases Dnmt3a and Dnmt3b regulate the onset of Igκ light chain rearrangement during early B-cell development.
Volume: 45
Issue: 8
Pages: 2343-55
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Publication
32445940 | J:298162
 
First Author: Casellas Román HL
Year: 2020
Journal: Leuk Res
Title: DNMT3A alterations associated with myeloid malignancies dictate differential responses to hypomethylating agents.
Volume: 94
Pages: 106372
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Publication
24497509 | J:206830
First Author: Xu J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells.
Volume: 111
Issue: 7
Pages: 2620-5
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Publication
16824199 | J:123369
First Author: Tsumura A
Year: 2006
Journal: Genes Cells
Title: Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b.
Volume: 11
Issue: 7
Pages: 805-14
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Publication
12787669 | J:83987
First Author: Reither S
Year: 2003
Journal: J Mol Biol
Title: Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme.
Volume: 329
Issue: 4
Pages: 675-84
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Publication
27824296 | J:264903
First Author: Hoang TV
Year: 2017
Journal: Epigenetics
Title: Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity.
Volume: 12
Issue: 1
Pages: 27-40
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Publication
24292811 | J:209078
First Author: Peters SL
Year: 2014
Journal: Leukemia
Title: Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis.
Volume: 28
Issue: 5
Pages: 1138-42
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GXD Expression
GXD Expression
Probe: MGI:3525854
Assay Type: Immunohistochemistry
Annotation Date: 2005-03-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3148228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3528428
Age: postnatal adult
Image: 5L
Note: Dnmt3a and Dnmt3b were not significantly expressed in the same spermatogonia.
Specimen Label: 5L
Detected: true
Specimen Num: 4
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Publication
21092094 | J:201511
First Author: Whitelaw NC
Year: 2010
Journal: Genome Biol
Title: Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.
Volume: 11
Issue: 11
Pages: R111
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Publication
11399089 | J:72444
First Author: Gowher H
Year: 2001
Journal: J Mol Biol
Title: Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites.
Volume: 309
Issue: 5
Pages: 1201-8
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Publication
10575238 | J:58633
First Author: Okano M
Year: 1999
Journal: Cytogenet Cell Genet
Title: Assignment of cytosine-5 DNA methyltransferases Dnmt3a and Dnmt3b to mouse chromosome bands 12A2-A3 and 2H1 by in situ hybridization.
Volume: 86
Issue: 3-4
Pages: 333-4
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Publication
19798101 | J:161259
First Author: Meilinger D
Year: 2009
Journal: EMBO Rep
Title: Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.
Volume: 10
Issue: 11
Pages: 1259-64
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Publication
15456878 | J:93321
First Author: Chen T
Year: 2004
Journal: Mol Cell Biol
Title: The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.
Volume: 24
Issue: 20
Pages: 9048-58
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Publication
12138111 | J:79451
First Author: Chen T
Year: 2002
Journal: J Biol Chem
Title: A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.
Volume: 277
Issue: 41
Pages: 38746-54
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Publication
37045808 | J:334894
First Author: Zioni N
Year: 2023
Journal: Nat Commun
Title: Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.
Volume: 14
Issue: 1
Pages: 2070
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Publication
29326230 | J:263288
First Author: Duncan CG
Year: 2018
Journal: G3 (Bethesda)
Title: Base-Resolution Analysis of DNA Methylation Patterns Downstream of Dnmt3a in Mouse Naïve B Cells.
Volume: 8
Issue: 3
Pages: 805-813
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Publication
34686499 | J:316880
First Author: Biran A
Year: 2021
Journal: Cancer Res
Title: Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Volume: 81
Issue: 24
Pages: 6117-6130
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Publication
24074865 | J:206847
First Author: Neri F
Year: 2013
Journal: Cell
Title: Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.
Volume: 155
Issue: 1
Pages: 121-34
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Publication
17687327 | J:123743
First Author: Ooi SK
Year: 2007
Journal: Nature
Title: DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.
Volume: 448
Issue: 7154
Pages: 714-7
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Publication
30834655 | J:294800
First Author: Sasaki K
Year: 2019
Journal: Mol Reprod Dev
Title: Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice.
Volume: 86
Issue: 6
Pages: 614-623
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Publication
30692594 | J:272803
     
First Author: Loberg MA
Year: 2019
Journal: Leukemia
Title: Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis.
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Publication
24599402 | J:210999
First Author: Hara S
Year: 2014
Journal: Hum Mol Genet
Title: Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting.
Volume: 23
Issue: 14
Pages: 3853-64
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Publication
38000729 | J:352183
 
First Author: Schwartz LS
Year: 2024
Journal: Exp Hematol
Title: Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells.
Volume: 130
Pages: 104131
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Publication
34698806 | J:325744
 
First Author: Kim PG
Year: 2021
Journal: J Exp Med
Title: Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.
Volume: 218
Issue: 12
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Publication
23399934 | J:195327
First Author: Qi L
Year: 2013
Journal: FEBS Lett
Title: miR-370 is stage-specifically expressed during mouse embryonic development and regulates Dnmt3a.
Volume: 587
Issue: 6
Pages: 775-81
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DO Term
DOID:0112339 | Tatton-Brown-Rahman syndrome
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Publication
33826889 | J:306547
First Author: Swahari V
Year: 2021
Journal: Cell Rep
Title: MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation.
Volume: 35
Issue: 1
Pages: 108946
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Publication
27134162 | J:235483
First Author: Haney SL
Year: 2016
Journal: Cell Rep
Title: Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.
Volume: 15
Issue: 6
Pages: 1190-201
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Publication
20651149 | J:162873
First Author: Wu H
Year: 2010
Journal: Science
Title: Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes.
Volume: 329
Issue: 5990
Pages: 444-8
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Publication
31792207 | J:284003
First Author: MacKay H
Year: 2019
Journal: Nat Commun
Title: DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice.
Volume: 10
Issue: 1
Pages: 5364
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Publication
17439403 | J:125563
First Author: Li B
Year: 2007
Journal: Biochem J
Title: Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a.
Volume: 405
Issue: 2
Pages: 369-78
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Publication
25634742 | J:222053
First Author: Hu W
Year: 2015
Journal: Blood
Title: miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a.
Volume: 125
Issue: 14
Pages: 2206-16
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Publication
29748607 | J:294778
First Author: Sun H
Year: 2018
Journal: Cell Death Dis
Title: MiR-455-3p inhibits the degenerate process of chondrogenic differentiation through modification of DNA methylation.
Volume: 9
Issue: 5
Pages: 537
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Publication
27387481 | J:240132
First Author: Kyono Y
Year: 2016
Journal: Endocrinology
Title: Liganded Thyroid Hormone Receptors Transactivate the DNA Methyltransferase 3a Gene in Mouse Neuronal Cells.
Volume: 157
Issue: 9
Pages: 3647-57
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Publication
14752048 | J:150923
First Author: Ling Y
Year: 2004
Journal: Nucleic Acids Res
Title: Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.
Volume: 32
Issue: 2
Pages: 598-610
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Publication
37024683 | J:355687
First Author: Ramabadran R
Year: 2023
Journal: Nat Cell Biol
Title: DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Volume: 25
Issue: 4
Pages: 528-539
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Publication
16362968 | J:106875
First Author: Yaman R
Year: 2006
Journal: Mol Reprod Dev
Title: Timing of entry of meiosis depends on a mark generated by DNA methyltransferase 3a in testis.
Volume: 73
Issue: 3
Pages: 390-7
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Publication
28872462 | J:247625
First Author: Cole CB
Year: 2017
Journal: J Clin Invest
Title: Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies.
Volume: 127
Issue: 10
Pages: 3657-3674
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Publication
33513138 | J:302985
First Author: Small L
Year: 2021
Journal: PLoS Genet
Title: Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity.
Volume: 17
Issue: 1
Pages: e1009325
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Publication
36271073 | J:346804
First Author: Fazio A
Year: 2022
Journal: Nat Commun
Title: DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon.
Volume: 13
Issue: 1
Pages: 6266
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Publication
12406579 | J:80002
First Author: Weisenberger DJ
Year: 2002
Journal: Gene
Title: Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells.
Volume: 298
Issue: 1
Pages: 91-9
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Publication
18191145 | J:166582
First Author: Dhayalan A
Year: 2008
Journal: J Mol Biol
Title: Mapping of protein-protein interaction sites by the 'absence of interference' approach.
Volume: 376
Issue: 4
Pages: 1091-9
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Publication
27306334 | J:239632
First Author: Fang X
Year: 2016
Journal: FASEB J
Title: Knockdown of DNA methyltransferase 3a alters gene expression and inhibits function of embryonic cardiomyocytes.
Volume: 30
Issue: 9
Pages: 3238-55
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Publication
33110091 | J:298101
First Author: Richard Albert J
Year: 2020
Journal: Nat Commun
Title: Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo.
Volume: 11
Issue: 1
Pages: 5417
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Publication
27582468 | J:238279
First Author: Ladle BH
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation.
Volume: 113
Issue: 38
Pages: 10631-6
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Publication
24941955 | J:212184
First Author: Lee SM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators.
Volume: 111
Issue: 26
Pages: 9555-60
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Publication
18541703 | J:137224
First Author: Jaco I
Year: 2008
Journal: J Cell Biol
Title: Centromere mitotic recombination in mammalian cells.
Volume: 181
Issue: 6
Pages: 885-92
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Publication
21706000 | J:176177
First Author: Smallwood SA
Year: 2011
Journal: Nat Genet
Title: Dynamic CpG island methylation landscape in oocytes and preimplantation embryos.
Volume: 43
Issue: 8
Pages: 811-4
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Publication
36169447 | J:347574
First Author: SanMiguel JM
Year: 2022
Journal: Cancer Discov
Title: Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis.
Volume: 12
Issue: 12
Pages: 2763-2773
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Publication
29765016 | J:263710
First Author: Barwick BG
Year: 2018
Journal: Nat Commun
Title: B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
Volume: 9
Issue: 1
Pages: 1900
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Publication
32203468 | J:316243
First Author: Izzo F
Year: 2020
Journal: Nat Genet
Title: DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Volume: 52
Issue: 4
Pages: 378-387
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Publication
29236683 | J:255701
First Author: Youngblood B
Year: 2017
Journal: Nature
Title: Effector CD8 T cells dedifferentiate into long-lived memory cells.
Volume: 552
Issue: 7685
Pages: 404-409
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Publication
26674863 | J:228501
First Author: Hodes GE
Year: 2015
Journal: J Neurosci
Title: Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress.
Volume: 35
Issue: 50
Pages: 16362-76
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Publication
26751286 | J:236575
First Author: Amouroux R
Year: 2016
Journal: Nat Cell Biol
Title: De novo DNA methylation drives 5hmC accumulation in mouse zygotes.
Volume: 18
Issue: 2
Pages: 225-233
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Publication
32561758 | J:292233
First Author: Dahlet T
Year: 2020
Journal: Nat Commun
Title: Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity.
Volume: 11
Issue: 1
Pages: 3153
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Publication
30644360 | J:278750
   
First Author: Luo C
Year: 2019
Journal: Elife
Title: Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons.
Volume: 8
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Publication
18953337 | J:245277
First Author: Epsztejn-Litman S
Year: 2008
Journal: Nat Struct Mol Biol
Title: De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes.
Volume: 15
Issue: 11
Pages: 1176-1183
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Publication
23393137 | J:203508
First Author: Chen CC
Year: 2013
Journal: J Biol Chem
Title: DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases.
Volume: 288
Issue: 13
Pages: 9084-91
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Publication
30832495 | J:297375
First Author: Ponnusamy M
Year: 2019
Journal: Circulation
Title: Long Noncoding RNA CPR (Cardiomyocyte Proliferation Regulator) Regulates Cardiomyocyte Proliferation and Cardiac Repair.
Volume: 139
Issue: 23
Pages: 2668-2684
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Publication
19625655 | J:151787
First Author: Gamper CJ
Year: 2009
Journal: J Immunol
Title: Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation.
Volume: 183
Issue: 4
Pages: 2267-76
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Publication
33850140 | J:305275
First Author: Mahajan VS
Year: 2021
Journal: Nat Commun
Title: B1a and B2 cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers.
Volume: 12
Issue: 1
Pages: 2208
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30385711 | J:280237
 
First Author: Kawakami-Mori F
Year: 2018
Journal: JCI Insight
Title: Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension.
Volume: 3
Issue: 21
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38795327 | J:350368
First Author: Yao S
Year: 2024
Journal: FASEB J
Title: Liver-specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high-fat diet-fed male mice.
Volume: 38
Issue: 10
Pages: e23690
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22190484 | J:179995
First Author: Yu Q
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation.
Volume: 109
Issue: 2
Pages: 541-6
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15757890 | J:99079
First Author: Dodge JE
Year: 2005
Journal: J Biol Chem
Title: Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.
Volume: 280
Issue: 18
Pages: 17986-91
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30684388 | J:295281
First Author: Mao Q
Year: 2019
Journal: Int J Cancer
Title: DNMT3a-triggered downregulation of K2p 1.1 gene in primary sensory neurons contributes to paclitaxel-induced neuropathic pain.
Volume: 145
Issue: 8
Pages: 2122-2134
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Publication
26876596 | J:231922
First Author: Scourzic L
Year: 2016
Journal: Leukemia
Title: DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
Volume: 30
Issue: 6
Pages: 1388-98
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Publication
16999741 | J:123366
First Author: Nimura K
Year: 2006
Journal: Genes Cells
Title: Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation.
Volume: 11
Issue: 10
Pages: 1225-37
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Publication
20507910 | J:173424
First Author: Shen L
Year: 2010
Journal: Nucleic Acids Res
Title: A single amino acid substitution confers enhanced methylation activity of mammalian Dnmt3b on chromatin DNA.
Volume: 38
Issue: 18
Pages: 6054-64
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Publication
27335278 | J:236423
First Author: Rau RE
Year: 2016
Journal: Blood
Title: DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
Volume: 128
Issue: 7
Pages: 971-81
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18559477 | J:137187
First Author: Hirasawa R
Year: 2008
Journal: Genes Dev
Title: Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development.
Volume: 22
Issue: 12
Pages: 1607-16
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Publication
29056337 | J:251368
First Author: Stroud H
Year: 2017
Journal: Cell
Title: Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States.
Volume: 171
Issue: 5
Pages: 1151-1164.e16
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11934864 | J:75938
First Author: Hata K
Year: 2002
Journal: Development
Title: Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice.
Volume: 129
Issue: 8
Pages: 1983-93
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Publication
25686699 | J:218442
First Author: Wang L
Year: 2015
Journal: Cell Res
Title: LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration.
Volume: 25
Issue: 3
Pages: 335-50
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Publication
17989773 | J:130349
First Author: Grandjean V
Year: 2007
Journal: PLoS One
Title: Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation.
Volume: 2
Issue: 11
Pages: e1136
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Publication
29464054 | J:310955
First Author: Deng L
Year: 2018
Journal: Oncotarget
Title: Rapid development of myeloproliferative neoplasm in mice with Ptpn11D61Y mutation and haploinsufficient for Dnmt3a.
Volume: 9
Issue: 5
Pages: 6055-6061
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Publication
34903841 | J:322606
First Author: Spohr C
Year: 2022
Journal: Leukemia
Title: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
Volume: 36
Issue: 4
Pages: 970-982
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Publication
35858425 | J:332877
First Author: Yue Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window.
Volume: 119
Issue: 30
Pages: e2201168119
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