Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Kinetochore-associated protein DSN1 homolog |
Type: |
chain |
End: |
348 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
348
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
232
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
124
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
65
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap E198C08, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap PST118, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap OST209869, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap OST374878, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; targeted mutation 1e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap EUCJ0019c07, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST12286C5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST10947B11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST13327F7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST13537E9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST14274H7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST15029D1, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
DSN1 homolog, MIS12 kinetochore complex component; gene trap IST15073A2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the kinetochore-associated protein Dsn1/Mis13.In Saccharomyces cerevisiae, Dsn1 acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules [, ].In Schizosaccharomyces pombe, Mis13 acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. It is required for correct segregation of chromosomes and for maintaining the inner centromere structure [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Wurzenberger C |
Year: |
2012 |
Journal: |
J Cell Biol |
Title: |
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. |
Volume: |
198 |
Issue: |
2 |
Pages: |
173-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayashi A |
Year: |
2006 |
Journal: |
Mol Biol Cell |
Title: |
Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe. |
Volume: |
17 |
Issue: |
12 |
Pages: |
5173-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Euskirchen GM |
Year: |
2002 |
Journal: |
Eukaryot Cell |
Title: |
Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae. |
Volume: |
1 |
Issue: |
2 |
Pages: |
229-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Wulf P |
Year: |
2003 |
Journal: |
Genes Dev |
Title: |
Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. |
Volume: |
17 |
Issue: |
23 |
Pages: |
2902-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu X |
Year: |
2005 |
Journal: |
EMBO J |
Title: |
Molecular analysis of kinetochore architecture in fission yeast. |
Volume: |
24 |
Issue: |
16 |
Pages: |
2919-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
|
•
•
•
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•
|