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Search results 101 to 192 out of 192 for Dtx3l

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0.024s
Type Details Score
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Weak
Sex: Female
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3783451
Age: postnatal week 12
Image: 5H
Specimen Label: 5H
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1741120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3783451
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1741122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3783451
Age: embryonic day 14.5
Image: 5B
Specimen Label: 5B
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10242
Specimen Label: GUDMAP:10242
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Male
Emaps: EMAPS:3580928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3783451
Age: postnatal week 12
Image: 5D
Specimen Label: 5D
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3783451
Age: postnatal week 12
Image: 5G
Specimen Label: 5G
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10242
Specimen Label: GUDMAP:10242
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10242
Specimen Label: GUDMAP:10242
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10242
Specimen Label: GUDMAP:10242
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Male
Emaps: EMAPS:1885228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3783451
Age: postnatal week 12
Note: Expression is in the epithelium.
Specimen Label: Not shown
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:3280922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3783451
Age: embryonic day 14.5
Image: 5B
Specimen Label: 5B
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1760420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3783451
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1760422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3783451
Age: embryonic day 14.5
Image: 5B
Specimen Label: 5B
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3783451
Age: postnatal week 12
Image: 5E
Note: Expression is in the epithelium.
Specimen Label: 5E
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10242
Specimen Label: GUDMAP:10242
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1789622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3783451
Age: embryonic day 14.5
Image: 5B
Specimen Label: 5B
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10242
Specimen Label: GUDMAP:10242
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1751520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3783451
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Female
Emaps: EMAPS:1751522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3783451
Age: embryonic day 14.5
Image: 5B
Specimen Label: 5B
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3783434
Assay Type: RNA in situ
Annotation Date: 2008-05-01
Strength: Present
Sex: Male
Emaps: EMAPS:3287328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3783451
Age: postnatal week 12
Note: Expression is in the follicle associated epithelium.
Specimen Label: Not shown
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:5001977
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542531
Age: embryonic day 15.5
Image: GUDMAP:10243
Specimen Label: GUDMAP:10243
Detected: true
Specimen Num: 2
Publication
First Author: Zhang Y
Year: 2015
Journal: Nat Immunol
Title: PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Volume: 16
Issue: 12
Pages: 1215-27
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
UniProt Feature
Begin: 2
Description: E3 ubiquitin-protein ligase DTX3L
Type: chain
End: 748
Publication
First Author: Huang J
Year: 2023
Journal: J Virol
Title: DTX3L Enhances Type I Interferon Antiviral Response by Promoting the Ubiquitination and Phosphorylation of TBK1.
Volume: 97
Issue: 6
Pages: e0068723
Interaction Experiment
Description: DTX3L Enhances Type I Interferon Antiviral Response by Promoting the Ubiquitination and Phosphorylation of TBK1.
Publication
First Author: Juszczynski P
Year: 2006
Journal: Mol Cell Biol
Title: BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate.
Volume: 26
Issue: 14
Pages: 5348-59
Publication
First Author: Holleman J
Year: 2014
Journal: Mol Biol Cell
Title: The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Volume: 25
Issue: 12
Pages: 1892-904
Protein Domain
Type: Domain
Description: DTX3L is a RING-domain E3 ubiquitin-protein ligase that regulates endosomal sorting of the G protein-coupled receptor CXCR4 from endosomes to lysosomes []. It also regulates subcellular localization of its partner protein, B aggressive lymphoma (BAL), by a dynamic nucleocytoplasmic trafficking mechanism [, }. DTX3L has a unique N terminus, but lacks the highly basic N-terminal motif and the central proline-rich motif present in other Deltex (DTX) family members, such as DTX1, DTX2, and DTX4. Moreover, its C-terminal region is highly homologous to DTX3. It includes a C3HC4-type RING-HC finger, and a previously unidentified C-terminal domain. DTX3L can associate with DTX1 through its unique N terminus and further enhance self-ubiquitination [].
Publication
First Author: Obiero J
Year: 2012
Journal: Proteins
Title: Fold of the conserved DTC domain in Deltex proteins.
Volume: 80
Issue: 5
Pages: 1495-9
Publication
First Author: Takeyama K
Year: 2003
Journal: J Biol Chem
Title: The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity.
Volume: 278
Issue: 24
Pages: 21930-7
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
Protein Domain
Type: Family
Description: The deltex family of proteins is involved in the regulation of Notch signaling, and therefore may play roles in cell-to-cell communications that regulate mechanisms determining cell fate []. They have a central RING-type zinc finger domain and contain a C-terminal domain that is also found inother domain architectures. Deltex-1 (DTX1) contains a RING finger and two WWE domains, indicating that it may be an E3 ubiquitin ligase []. Human deltex 3-like, which contains an additional N-terminal domain (presumably with ubiquitin ligase activity) is also described as E3 ubiquitin-protein ligase DTX3L, B-lymphoma- and BAL-associated protein (BBAP), or rhysin-2. DTX3L mediates monoubiquitination of K91 of histone H4 in response to DNA damage [, ].
Publication
First Author: Matsuno K
Year: 1998
Journal: Nat Genet
Title: Human deltex is a conserved regulator of Notch signalling.
Volume: 19
Issue: 1
Pages: 74-8
Publication
First Author: Zhang P
Year: 2010
Journal: Oncogene
Title: Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness.
Volume: 29
Issue: 20
Pages: 2916-26
Protein Domain
Type: Domain
Description: The deltex family of proteins is involved in the regulation of Notch signaling, and therefore may play roles in cell-to-cell communications that regulate mechanisms determining cell fate []. They have a central RING-type zinc finger domain and contain a C-terminal domain that is also found in other domain architectures. Deltex-1 (DTX1) contains a RING finger and two WWE domains, indicating that it may be an E3 ubiquitin ligase []. Human deltex 3-like, which contains an additional N-terminal domain (presumably with ubiquitin ligase activity) is also described as E3 ubiquitin-protein ligase DTX3L, B-lymphoma- and BAL-associated protein (BBAP), or rhysin-2. DTX3L mediates monoubiquitination of K91 of histone H4 in response to DNA damage [, ].This entry represents the C-terminal domain of the Deltex proteins.
Protein Domain
Type: Homologous_superfamily
Description: The deltex family of proteins is involved in the regulation of Notch signaling, and therefore may play roles in cell-to-cell communications that regulate mechanisms determining cell fate []. They have a central RING-type zinc finger domain and contain a C-terminal domain that is also found in other domain architectures. Deltex-1 (DTX1) contains a RING finger and two WWE domains, indicating that it may be an E3 ubiquitin ligase []. Human deltex 3-like, which contains an additional N-terminal domain (presumably with ubiquitin ligase activity) is also described as E3 ubiquitin-protein ligase DTX3L, B-lymphoma- and BAL-associated protein (BBAP), or rhysin-2. DTX3L mediates monoubiquitination of K91 of histone H4 in response to DNA damage [, ].This entry represents the C-terminal domain of the Deltex proteins. It contains a fold composed of central β-sheet lined with two long parallel α-helices [].
Protein
Organism: Mus musculus/domesticus
Length: 34  
Fragment?: false
Publication
First Author: Choi D
Year: 2022
Journal: Circ Res
Title: Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion.
Volume: 131
Issue: 2
Pages: e2-e21
Protein
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 627  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 619  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 616  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89