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Search results 101 to 200 out of 605 for Dyrk1a

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:2663745
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666304
Age: embryonic day 10.5
Image: Dyrk1a 10.5dpc
Specimen Label: Dyrk1a 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2663746
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666305
Age: embryonic day 10.5
Image: Dyrk1a 10.5dpc
Specimen Label: Dyrk1a 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2663745
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796222
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666304
Age: embryonic day 14.5
Image: Dyrk1a 14.5dpc
Specimen Label: Dyrk1a 14.5dpc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2663746
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796222
Pattern: Uniform
Stage: TS22
Assay Id: MGI:2666305
Age: embryonic day 14.5
Image: Dyrk1a 14.5dpc
Specimen Label: Dyrk1a 14.5dpc
Detected: true
Specimen Num: 2
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Publication
27216978 | J:256279
First Author: Renon M
Year: 2016
Journal: Biochim Biophys Acta
Title: Impact of Dyrk1A level on alcohol metabolism.
Volume: 1862
Issue: 9
Pages: 1495-503
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Protein
Q61158
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
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Publication
21965663 | J:178153
First Author: Jung MS
Year: 2011
Journal: J Biol Chem
Title: Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.
Volume: 286
Issue: 46
Pages: 40401-12
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Publication
19801542 | J:156321
First Author: Lee Y
Year: 2009
Journal: J Biol Chem
Title: Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis.
Volume: 284
Issue: 48
Pages: 33343-51
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Publication
26953159 | J:249662
First Author: Dirice E
Year: 2016
Journal: Diabetes
Title: Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Volume: 65
Issue: 6
Pages: 1660-71
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Publication
20696760 | J:166796
First Author: Park J
Year: 2010
Journal: J Biol Chem
Title: Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
Volume: 285
Issue: 41
Pages: 31895-906
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Publication
24870561 | J:223497
First Author: Rachdi L
Year: 2014
Journal: Cell Cycle
Title: Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance.
Volume: 13
Issue: 14
Pages: 2221-9
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Publication
24801365 | J:214001
 
First Author: Souchet B
Year: 2014
Journal: Neurobiol Dis
Title: Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.
Volume: 69
Pages: 65-75
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Publication
34828406 | J:324151
 
First Author: Dard R
Year: 2021
Journal: Genes (Basel)
Title: DYRK1A Overexpression in Mice Downregulates the Gonadotropic Axis and Disturbs Early Stages of Spermatogenesis.
Volume: 12
Issue: 11
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Publication
16455265 | J:111293
First Author: Ahn KJ
Year: 2006
Journal: Neurobiol Dis
Title: DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects.
Volume: 22
Issue: 3
Pages: 463-72
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Publication
20167603 | J:165940
First Author: Guo X
Year: 2010
Journal: J Biol Chem
Title: DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.
Volume: 285
Issue: 17
Pages: 13223-32
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Publication
25490145 | J:221510
First Author: Kariyawasam D
Year: 2015
Journal: Endocrinology
Title: DYRK1A BAC transgenic mouse: a new model of thyroid dysgenesis in Down syndrome.
Volume: 156
Issue: 3
Pages: 1171-80
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Publication
29742440 | J:270830
First Author: Rozen EJ
Year: 2018
Journal: Cell Rep
Title: DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.
Volume: 23
Issue: 6
Pages: 1867-1878
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Publication
22765017 | J:187626
First Author: Park JH
Year: 2012
Journal: J Neurochem
Title: Phosphorylation of Munc18-1 by Dyrk1A regulates its interaction with Syntaxin 1 and X11α.
Volume: 122
Issue: 5
Pages: 1081-91
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Publication
20123978 | J:161722
First Author: Kurabayashi N
Year: 2010
Journal: Mol Cell Biol
Title: DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping.
Volume: 30
Issue: 7
Pages: 1757-68
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Publication
23920041 | J:205302
First Author: Tlili A
Year: 2013
Journal: Mol Genet Metab
Title: DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels.
Volume: 110
Issue: 3
Pages: 371-7
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Publication
27056896 | J:252570
First Author: Hille S
Year: 2016
Journal: Cardiovasc Res
Title: Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.
Volume: 110
Issue: 3
Pages: 381-94
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Publication
20600907 | J:163008
First Author: Toiber D
Year: 2010
Journal: Neurobiol Dis
Title: Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.
Volume: 40
Issue: 1
Pages: 348-59
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Publication
19081073 | J:144220
First Author: Laguna A
Year: 2008
Journal: Dev Cell
Title: The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.
Volume: 15
Issue: 6
Pages: 841-53
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Publication
22178546 | J:182642
First Author: Noll C
Year: 2012
Journal: Mol Genet Metab
Title: Dyrk1a activates antioxidant NQO1 expression through an ERK1/2-Nrf2 dependent mechanism.
Volume: 105
Issue: 3
Pages: 484-8
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Publication
23512985 | J:198546
First Author: Laguna A
Year: 2013
Journal: Hum Mol Genet
Title: Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.
Volume: 22
Issue: 14
Pages: 2775-84
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Publication
37797581 | J:341983
First Author: Shih YT
Year: 2023
Journal: Neuron
Title: An inhibitory circuit-based enhancer of DYRK1A function reverses Dyrk1a-associated impairment in social recognition.
Volume: 111
Issue: 19
Pages: 3084-3101.e5
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Publication
25998054 | J:223409
   
First Author: Khor B
Year: 2015
Journal: Elife
Title: The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
Volume: 4
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Publication
- | J:361105
     
First Author: Tateossian H
Year: 2025
Journal: Elife
Title: DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome.
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Publication
16554754 | J:109139
First Author: Arron JR
Year: 2006
Journal: Nature
Title: NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Volume: 441
Issue: 7093
Pages: 595-600
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Publication
34255829 | J:335034
First Author: Li Y
Year: 2021
Journal: Blood
Title: DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.
Volume: 138
Issue: 23
Pages: 2360-2371
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Publication
26373433 | J:315860
First Author: Kurabayashi N
Year: 2015
Journal: EMBO Rep
Title: DYRK1A overexpression enhances STAT activity and astrogliogenesis in a Down syndrome mouse model.
Volume: 16
Issue: 11
Pages: 1548-62
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Publication
14751778 | J:128773
First Author: Martínez de Lagrán M
Year: 2004
Journal: Neurobiol Dis
Title: Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction.
Volume: 15
Issue: 1
Pages: 132-42
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Publication
37992782 | J:343255
 
First Author: Hawley LE
Year: 2023
Journal: Neurobiol Dis
Title: Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model.
Volume: 190
Pages: 106359
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Publication
22215728 | J:203029
First Author: Martinez de Lagran M
Year: 2012
Journal: Cereb Cortex
Title: Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons.
Volume: 22
Issue: 12
Pages: 2867-77
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Publication
15199138 | J:91599
First Author: Sitz JH
Year: 2004
Journal: Mol Cell Biol
Title: Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4.
Volume: 24
Issue: 13
Pages: 5821-34
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Publication
24477974 | J:210093
First Author: Rachdi L
Year: 2014
Journal: Diabetologia
Title: Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass.
Volume: 57
Issue: 5
Pages: 960-9
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Publication
26008897 | J:223138
First Author: Thompson BJ
Year: 2015
Journal: J Exp Med
Title: DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3.
Volume: 212
Issue: 6
Pages: 953-70
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Publication
12192061 | J:78597
First Author: Fotaki V
Year: 2002
Journal: Mol Cell Biol
Title: Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice.
Volume: 22
Issue: 18
Pages: 6636-47
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Publication
30831192 | J:278114
 
First Author: Arranz J
Year: 2019
Journal: Neurobiol Dis
Title: Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome.
Volume: 127
Pages: 210-222
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Publication
37310920 | J:341033
First Author: Strine MS
Year: 2023
Journal: PLoS Biol
Title: DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Volume: 21
Issue: 6
Pages: e3002097
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Publication
35925681 | J:344352
 
First Author: Elagib KE
Year: 2022
Journal: J Clin Invest
Title: Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes.
Volume: 132
Issue: 19
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Publication
18940310 | J:140647
First Author: Ortiz-Abalia J
Year: 2008
Journal: Am J Hum Genet
Title: Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.
Volume: 83
Issue: 4
Pages: 479-88
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Publication
24922073 | J:316661
 
First Author: Barallobre MJ
Year: 2014
Journal: Cell Death Dis
Title: DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease.
Volume: 5
Pages: e1289
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Publication
15301607 | J:105130
First Author: Fotaki V
Year: 2004
Journal: Behav Neurosci
Title: Haploinsufficiency of Dyrk1A in mice leads to specific alterations in the development and regulation of motor activity.
Volume: 118
Issue: 4
Pages: 815-21
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Publication
12576186 | J:81873
First Author: Martí E
Year: 2003
Journal: Brain Res
Title: Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system.
Volume: 964
Issue: 2
Pages: 250-63
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Publication
19218269 | J:146836
First Author: Lepagnol-Bestel AM
Year: 2009
Journal: Hum Mol Genet
Title: DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome.
Volume: 18
Issue: 8
Pages: 1405-14
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Publication
28137862 | J:240939
First Author: Xiang J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome.
Volume: 114
Issue: 7
Pages: E1224-E1233
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Publication
29434250 | J:262731
First Author: Neumann F
Year: 2018
Journal: Sci Rep
Title: DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives.
Volume: 8
Issue: 1
Pages: 2859
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Publication
23429073 | J:202433
First Author: Tlili A
Year: 2013
Journal: Biochim Biophys Acta
Title: Hepatocyte-specific Dyrk1a gene transfer rescues plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic mice.
Volume: 1832
Issue: 6
Pages: 718-28
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Publication
28172997 | J:241781
First Author: McElyea SD
Year: 2016
Journal: Hum Mol Genet
Title: Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.
Volume: 25
Issue: 22
Pages: 4856-4869
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Publication
38266108 | J:345472
First Author: Lana-Elola E
Year: 2024
Journal: Sci Transl Med
Title: Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome.
Volume: 16
Issue: 731
Pages: eadd6883
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Publication
24352425 | J:205486
First Author: Kurabayashi N
Year: 2013
Journal: Genes Dev
Title: Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells.
Volume: 27
Issue: 24
Pages: 2708-21
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Publication
33840455 | J:321249
First Author: Levy JA
Year: 2021
Journal: Biol Psychiatry
Title: Dyrk1a Mutations Cause Undergrowth of Cortical Pyramidal Neurons via Dysregulated Growth Factor Signaling.
Volume: 90
Issue: 5
Pages: 295-306
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Publication
11555628 | J:71821
First Author: Altafaj X
Year: 2001
Journal: Hum Mol Genet
Title: Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.
Volume: 10
Issue: 18
Pages: 1915-23
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Publication
23342120 | J:195697
First Author: Arque G
Year: 2013
Journal: PLoS One
Title: Dyrk1A is dynamically expressed on subsets of motor neurons and in the neuromuscular junction: possible role in Down syndrome.
Volume: 8
Issue: 1
Pages: e54285
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Publication
21273244 | J:186004
First Author: Grebe C
Year: 2011
Journal: Cardiovasc Res
Title: Enhanced expression of DYRK1A in cardiomyocytes inhibits acute NFAT activation but does not prevent hypertrophy in vivo.
Volume: 90
Issue: 3
Pages: 521-8
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Publication
25188425 | J:223423
First Author: García-Cerro S
Year: 2014
Journal: PLoS One
Title: Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome.
Volume: 9
Issue: 9
Pages: e106572
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Publication
23220201 | J:197665
 
First Author: Altafaj X
Year: 2013
Journal: Neurobiol Dis
Title: Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome.
Volume: 52
Pages: 117-27
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Publication
32081899 | J:297885
First Author: Classen J
Year: 2020
Journal: Sci Rep
Title: A Munc18-1 mutant mimicking phosphorylation by Down Syndrome-related kinase Dyrk1a supports normal synaptic transmission and promotes recovery after intense activity.
Volume: 10
Issue: 1
Pages: 3181
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Publication
20804972 | J:164437
First Author: Ferron SR
Year: 2010
Journal: Cell Stem Cell
Title: Regulated segregation of kinase Dyrk1A during asymmetric neural stem cell division is critical for EGFR-mediated biased signaling.
Volume: 7
Issue: 3
Pages: 367-79
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Publication
28647555 | J:260246
 
First Author: García-Cerro S
Year: 2017
Journal: Neurobiol Dis
Title: Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
Volume: 106
Pages: 76-88
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Publication
20736167 | J:183209
First Author: Li D
Year: 2010
Journal: J Biol Chem
Title: Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions.
Volume: 285
Issue: 46
Pages: 35374-85
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Publication
37102702 | J:335294
 
First Author: Redhead Y
Year: 2023
Journal: Development
Title: Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes.
Volume: 150
Issue: 8
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Publication
15198122 | J:292873
First Author: Branchi I
Year: 2004
Journal: J Neuropathol Exp Neurol
Title: Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration.
Volume: 63
Issue: 5
Pages: 429-40
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Publication
22354171 | J:184564
First Author: Malinge S
Year: 2012
Journal: J Clin Invest
Title: Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.
Volume: 122
Issue: 3
Pages: 948-62
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Publication
34587162 | J:311493
First Author: Brault V
Year: 2021
Journal: PLoS Genet
Title: Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.
Volume: 17
Issue: 9
Pages: e1009777
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Publication
24453307 | J:206860
First Author: Thomazeau A
Year: 2014
Journal: J Neurosci
Title: Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.
Volume: 34
Issue: 4
Pages: 1138-47
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Publication
17906291 | J:128996
First Author: Ryoo SR
Year: 2007
Journal: J Biol Chem
Title: DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Volume: 282
Issue: 48
Pages: 34850-7
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Publication
35914814 | J:333903
 
First Author: Viard J
Year: 2022
Journal: Life Sci Alliance
Title: Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.
Volume: 5
Issue: 12
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Publication
7857639 | J:37070
First Author: Tejedor F
Year: 1995
Journal: Neuron
Title: minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.
Volume: 14
Issue: 2
Pages: 287-301
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Publication
30649339 | J:273645
First Author: Marechal D
Year: 2019
Journal: Hum Mol Genet
Title: Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a.
Volume: 28
Issue: 9
Pages: 1561-1577
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Publication
26374847 | J:224899
First Author: Jiang X
Year: 2015
Journal: Hum Mol Genet
Title: Genetic dissection of the Down syndrome critical region.
Volume: 24
Issue: 22
Pages: 6540-51
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Publication
22293606 | J:182294
First Author: Guedj F
Year: 2012
Journal: Neurobiol Dis
Title: DYRK1A: a master regulatory protein controlling brain growth.
Volume: 46
Issue: 1
Pages: 190-203
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Publication
16137572 | J:102616
First Author: Benavides-Piccione R
Year: 2005
Journal: Neurobiol Dis
Title: Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse.
Volume: 20
Issue: 1
Pages: 115-22
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Publication
31086297 | J:278677
First Author: Granno S
Year: 2019
Journal: Sci Rep
Title: Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Volume: 9
Issue: 1
Pages: 7322
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Publication
38569042 | J:349700
First Author: Cortes DE
Year: 2024
Journal: Sci Adv
Title: An in vitro neurogenetics platform for precision disease modeling in the mouse.
Volume: 10
Issue: 14
Pages: eadj9305
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Publication
29223763 | J:259596
 
First Author: Raveau M
Year: 2018
Journal: Neurobiol Dis
Title: DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures.
Volume: 110
Pages: 180-191
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Publication
38461326 | J:346987
First Author: Hu K
Year: 2024
Journal: Commun Biol
Title: MicroRNA-221-3p inhibits the inflammatory response of keratinocytes by regulating the DYRK1A/STAT3 signaling pathway to promote wound healing in diabetes.
Volume: 7
Issue: 1
Pages: 300
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Publication
18773961 | J:142428
First Author: Altafaj X
Year: 2008
Journal: Neurobiol Dis
Title: Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.
Volume: 32
Issue: 3
Pages: 377-84
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Publication
29746474 | J:262380
First Author: Watson-Scales S
Year: 2018
Journal: PLoS Genet
Title: Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.
Volume: 14
Issue: 5
Pages: e1007383
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Publication
17137466 | J:137755
First Author: Martinez de Lagran M
Year: 2007
Journal: Genes Brain Behav
Title: Dopaminergic deficiency in mice with reduced levels of the dual-specificity tyrosine-phosphorylated and regulated kinase 1A, Dyrk1A(+/-).
Volume: 6
Issue: 6
Pages: 569-78
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Publication
26206885 | J:226041
First Author: Blazek JD
Year: 2015
Journal: Hum Mol Genet
Title: Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a.
Volume: 24
Issue: 20
Pages: 5687-96
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Publication
37997361 | J:354660
 
First Author: Manubens-Gil L
Year: 2024
Journal: Cereb Cortex
Title: Deficits in neuronal architecture but not over-inhibition are main determinants of reduced neuronal network activity in a mouse model of overexpression of Dyrk1A.
Volume: 34
Issue: 1
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Publication
21878370 | J:182785
 
First Author: Kida E
Year: 2011
Journal: Neuroscience
Title: Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.
Volume: 195
Pages: 112-27
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Publication
19383720 | J:150493
First Author: Fernandez-Martinez J
Year: 2009
Journal: J Cell Sci
Title: Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A.
Volume: 122
Issue: Pt 10
Pages: 1574-83
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Publication
18938227 | J:144655
First Author: Sitz JH
Year: 2008
Journal: Neuroscience
Title: The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4.
Volume: 157
Issue: 3
Pages: 596-605
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Publication
21470964 | J:182960
First Author: Qian W
Year: 2011
Journal: Nucleic Acids Res
Title: Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A.
Volume: 39
Issue: 14
Pages: 6161-71
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Publication
19844572 | J:154042
First Author: Noll C
Year: 2009
Journal: PLoS One
Title: DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.
Volume: 4
Issue: 10
Pages: e7540
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Publication
24327345 | J:252003
First Author: Kaczmarski W
Year: 2014
Journal: J Neurosci Res
Title: Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).
Volume: 92
Issue: 2
Pages: 162-73
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Publication
18678649 | J:140347
First Author: Aranda S
Year: 2008
Journal: Mol Cell Biol
Title: Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.
Volume: 28
Issue: 19
Pages: 5899-911
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Publication
28775333 | J:319245
First Author: Wang P
Year: 2017
Journal: Sci Rep
Title: Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D.
Volume: 7
Issue: 1
Pages: 7240
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Publication
18648535 | J:138236
First Author: Arqué G
Year: 2008
Journal: PLoS One
Title: Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).
Volume: 3
Issue: 7
Pages: e2575
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Publication
27030752 | J:231752
First Author: Ruiz-Mejias M
Year: 2016
Journal: J Neurosci
Title: Overexpression of Dyrk1A, a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex.
Volume: 36
Issue: 13
Pages: 3648-59
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Publication
31240602 | J:295562
First Author: Velazquez R
Year: 2019
Journal: Mol Neurobiol
Title: Chronic Dyrk1 Inhibition Delays the Onset of AD-Like Pathology in 3xTg-AD Mice.
Volume: 56
Issue: 12
Pages: 8364-8375
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Publication
31723029 | J:282802
First Author: Tian S
Year: 2019
Journal: J Biol Chem
Title: Dual-specificity tyrosine phosphorylation-regulated kinase 1A ameliorates insulin resistance in neurons by up-regulating IRS-1 expression.
Volume: 294
Issue: 52
Pages: 20164-20176
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Publication
18771760 | J:140118
First Author: Canzonetta C
Year: 2008
Journal: Am J Hum Genet
Title: DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome.
Volume: 83
Issue: 3
Pages: 388-400
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Publication
35810562 | J:326761
 
First Author: Lan C
Year: 2022
Journal: EBioMedicine
Title: Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction.
Volume: 82
Pages: 104139
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Publication
- | J:343786
     
First Author: Lana-Elola E
Year: 2023
Journal: bioRxiv
Title: Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A.
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Publication
9748265 | J:50326
First Author: Becker W
Year: 1998
Journal: J Biol Chem
Title: Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.
Volume: 273
Issue: 40
Pages: 25893-902
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Publication
28779511 | J:248482
First Author: Branca C
Year: 2017
Journal: Aging Cell
Title: Dyrk1 inhibition improves Alzheimer's disease-like pathology.
Volume: 16
Issue: 5
Pages: 1146-1154
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